Glial activation and post-synaptic neurotoxicity: The key events in Streptozotocin (ICV) induced memory impairment in rats

Pharmacology Biochemistry and Behavior

Volumn 117, Issue , 2014, Pages 104-117

  Rai, Shivika ^a   Kamat, Pradeep K ^b   Nath, Chandishwar ^a   Shukla, Rakesh ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b University of Louisville School of Medicine   (United States)

Author keywords

Free radicals; Glial activation; Memory impairment; Streptozotocin; Synaptic markers

Indexed keywords

CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CASPASE 3; CD11B ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; IBUPROFEN; MEMANTINE; NITRITE; POSTSYNAPTIC DENSITY PROTEIN 95; REACTIVE OXYGEN METABOLITE; STREPTOZOCIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; CELL ACTIVATION; CELL DEATH; CONTROLLED STUDY; EXCITOTOXICITY; GLIA CELL; HIPPOCAMPUS; LOCOMOTION; MALE; MEMORY DISORDER; METABOLIC ACTIVITY ASSAY; MORRIS WATER MAZE TEST; NERVOUS SYSTEM INFLAMMATION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

1-(NAPHTHYL) ETHYLENEDIAMINE DIHYDROCHLORIDE; 2, 7 DICHLOROFLUORESCEIN; 3-[4,5-DIMETHYL-THIOZOL-2-YL]-2,5 DIPHENYL TETRAZOLIUM BROMIDE; ACSF; ARTIFICIAL CEREBROSPINAL FLUID; CALMODULIN KINASEIIΑ; CAMKIIΑ; DCF; ELT; ESCAPE LATENCY TIMES; FREE RADICALS; FURA-2 ACETOXY-METHYL ESTER; FURA-2AM; GFAP; GLIAL ACTIVATION; GLIAL FIBRIC ACIDIC PROTEIN; ICV; INTRACEREBROVENTRICULAR; MEMORY IMPAIRMENT; MTT; NEDA; POST SYNAPTIC DENSITY; PSD; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; RNS; ROS; SNAP25; STREPTOZOTOCIN; STZ; SYNAPTIC MARKERS; SYNAPTOSOME ASSOCIATED PROTEIN;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; INJECTIONS, INTRAVENTRICULAR; LOCOMOTION; MALE; MEMORY DISORDERS; NEUROGLIA; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN; SYNAPSES;

EID: 84891686758     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2013.11.035     Document Type: Article

References (44)

1. A. Alvarez, R. Cacabelos, C. Sanpedro, M. Garcia-Fantini, and M. Aleixandre Serum TNF-alpha Levels are increased and correlate negatively with free IGF-I in Alzheimer disease Neurobiol Aging 28 2006 533 536
2. A. Araque, N. Li, R.T. Doyle, and P.G. Haydon SNARE protein-dependent glutamate release from astrocytes J Neurosci 20 2000 666 673 (Pubitemid 30225569)
3. R. Agrawal, E. Tyagi, R. Shukla, and C. Nath A study of brain insulin receptors, AChE activity and oxidative stress in rat model of ICV STZ induced dementia Neuropharmacology 56 2009 779 787
4. M.J. Berridge, P. Lipp, and M.D. Bootman The versatility and universality of calcium signalling Nat Rev Mol Cell Biol 1 2000 11 21
5. S. Bleich, K. Romer, J. Wiltfang, and J. Kornhuber Glutamate and the glutamate receptor system: a target for drug action Int J Geriatr Psychiatry 18 Suppl. 1 2003 S33 S40
6. A.P. Braun, and H. Schulman The multifunctional calcium/calmodulin- dependent protein kinase: from form to function Annu Rev Physiol 57 1995 417 445
7. L. Crews, and E. Masliah Molecular mechanisms of neurodegeneration in Alzheimer's disease Hum Mol Genet 19 2010 R12 R20
8. J. Cheriyan, P. Kumar, M. Mayadevi, A. Surolia, R.V. Omkumar, and R. Linden Calcium/calmodulin dependent protein kinase II bound to NMDA receptor 2B subunit exhibits increased ATP affinity and attenuated dephosphorylation PLoS One 6 2011 e16495
9. W. Danysz, and C.G. Parsons The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence Int J Geriatr Psychiatry 18 2003 S23 S32
10. T. Deak, C. Bellamy, and L.G. D'Agostino Exposure to forced swim stress does not alter central production of IL-1 Brain Res 972 2003 53 63 (Pubitemid 36507077)
11. E. Engidawork, T. Gulesserian, B.C. Yoo, N. Cairns, and G. Lubec Alteration of caspases and apoptosis-related proteins in brains of patients with Alzheimer's disease Biochem Biophys Res Commun 281 2001 84 93 (Pubitemid 32924403)
12. J. Glowinski, and L.L. Iversen Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain J Neurochem 13 1966 655 669
13. L.C. Green, D.A. Wagner, J. Glogowski, P.L. Skipper, J.S. Wishnok, and S.R. Tannenbaum Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids Anal Biochem 126 1982 131 138 (Pubitemid 13203451)
14. 2 + indicators with greatly improved fluorescence properties J Biol Chem 260 1985 3440 3450 (Pubitemid 15114340)
15. B. Halliwell, O.I. Aruoma, M. Wasil, and J.M. Gutteridge The resistance of transferrin, lactoferrin and caeruloplasmin to oxidative damage Biochem J 256 1988 311 312
16. P.K. Kamat, S. Tota, G. Saxena, R. Shukla, and C. Nath Okadaic acid (ICV) induced memory impairment in rats: a suitable experimental model to test anti-dementia activity Brain Res 1309 2010 66 74
17. P.K. Kamat, S. Tota, R. Shukla, S. Ali, A.K. Najmi, and C. Nath Mitochondrial dysfunction: a crucial event in okadaic acid (I.C.V) induced memory impairment and apoptotic cell death in rat brain Pharmacol Biochem Behav 100 2011 311 319
18. P.K. Kamat, S. Rai, S. Swarnkar, R. Shukla, S. Ali, and A.K. Najmi et al. Okadaic acid-induced Tau phosphorylation in rat brain: role of NMDA receptor Neuroscience 238 2013 97 113 [5]
19. J.N. Keller, M.S. Kindy, F.W. Holtsberg, D.K. St Clair, H.C. Yen, and A. Germeyer et al. Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction J Neurosci 18 1998 687 697 (Pubitemid 28041905)
20. M.B. Kennedy Signal-processing machines at the postsynaptic density Science 290 2000 750 754
21. P.R. Kennedy, and R.A. Bakay Activity of single action potentials in monkey motor cortex during long-term task learning Brain Res 760 1997 251 254 (Pubitemid 27304160)
22. D.Y. Lee, Y.J. Oh, and B.K. Jin Thrombin-activated microglia contribute to death of dopaminergic neurons in rat mesencephalic cultures: dual roles of mitogen-activated protein kinase signaling pathways Glia 51 2005 98 110 (Pubitemid 41277344)
23. J. Lisman The CaM kinase II hypothesis for the storage of synaptic memory Trends Neurosci 17 1994 406 412 (Pubitemid 24288205)
24. Y.W. Liu, T. Sakaeda, K. Takara, T. Nakamura, N. Ohmoto, and C. Komoto et al. Effects of reactive oxygen species on cell proliferation and death in HeLa cells and its MDR1-overexpressing derivative cell line Biol Pharm Bull 26 2003 278 281 (Pubitemid 41699680)
25. K.P. Loh, S.H. Huang, R. De Silva, B.K. Tan, and Y.Z. Zhu Oxidative stress: apoptosis in neuronal injury Curr Alzheimer Res 3 2006 327 337 (Pubitemid 44351476)
26. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent J Biol Chem 193 1951 265 275
27. + and ATP-stimulated rodent cortex synaptosomes Neurosci Res Commun 27 2000 103 107
28. E. Masliah, M. Mallory, M. Alford, R. DeTeresa, L.A. Hansen, and D.W. McKeel Jr. et al. Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease Neurology 56 2001 127 129 (Pubitemid 32059669)
29. M.P. Mattson, B. Cheng, D. Davis, K. Bryant, I. Lieberburg, and R.E. Rydel Beta-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity J Neurosci 12 1992 376 389
30. S. McGovern, M.E. Maguire, R.S. Gurd, H.R. Mahler, and W.J. Moore Separation of adrenergic and cholinergic synaptosomes from immature rat brain FEBS Lett 31 1973 193 198
31. L. Meda, P. Baron, and G. Scarlato Glial activation in Alzheimer's disease: the role of A beta and its associated proteins Neurobiol Aging 22 2001 885 893 (Pubitemid 34066555)
32. R.L. Michaels, and S.M. Rothman Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations J Neurosci 10 1990 283 292 (Pubitemid 20059264)
33. R.E. Mrak, and W.S. Griffin Interleukin-1, neuroinflammation, and Alzheimer's disease Neurobiol Aging 22 2001 903 908 (Pubitemid 34066557)
34. X. Mungarro-Menchaca, P. Ferrera, J. Moran, and C. Arias beta-Amyloid peptide induces ultrastructural changes in synaptosomes and potentiates mitochondrial dysfunction in the presence of ryanodine J Neurosci Res 68 2002 89 96 (Pubitemid 34275001)
35. O. Myhre, J.M. Andersen, H. Aarnes, and F. Fonnum Evaluation of the probes 2′,7′-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation Biochem Pharmacol 65 2003 1575 1582 (Pubitemid 36581871)
36. T. Nagatsu, M. Mogi, H. Ichinose, and A. Togari Changes in cytokines and neurotrophins in Parkinson's disease J Neural Transm 2000 277 290 [Suppl.] (Pubitemid 32037200)
37. G. Paxinos, C.R. Watson, and P.C. Emson AChE-stained horizontal sections of the rat brain in stereotaxic coordinates J Neurosci Methods 3 1980 129 149 (Pubitemid 11162950)
38. S. Rai, P.K. Kamat, C. Nath, and R. Shukla A study on neuroinflammation and NMDA receptor function in STZ (ICV) induced memory impaired rats J Neuroimmunol 254 2013 1 9
39. D.J. Selkoe Alzheimer's disease: genes, proteins, and therapy Physiol Rev 81 2001 741 766 (Pubitemid 32267077)
40. C.G. Schipke, C. Ohlemeyer, M. Matyash, C. Nolte, H. Kettenmann, and F. Kirchhoff Astrocytes of the mouse neocortex express functional N-methyl-D-aspartate receptors FASEB J 15 2001 1270 1272
41. A.J. Silva, C.F. Stevens, S. Tonegawa, and Y. Wang Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice Science 257 1992 201 206
42. S. Shoham, C. Bejar, E. Kovalev, and M. Weinstock Intracerebroventricular injection of streptozotocin causes neurotoxicity to myelin that contributes to spatial memory deficits in rats Exp Neurol 184 2003 1043 1052 (Pubitemid 38182835)
43. M. Valko, D. Leibfritz, J. Moncol, M.T. Cronin, M. Mazur, and J. Telser Free radicals and antioxidants in normal physiological functions and human disease Int J Biochem Cell Biol 39 2007 44 84 (Pubitemid 44566469)
44. J. Yuan, and B.A. Yankner Apoptosis in the nervous system Nature 407 2000 802 809