Liver X receptor agonist T0901317 reduces neuropathological changes and improves memory in mouse models of experimental dementia

European Journal of Pharmacology

Volumn 732, Issue 1, 2014, Pages 50-59

  Sodhi, Rupinder K ^a   Singh, Nirmal ^a  

^a PUNJABI UNIVERSITY   (India)

Author keywords

Dementia; High fat diet; Liver X receptors; Streptozotocin; T0901317

Indexed keywords

ACETYLCHOLINESTERASE; AMYLOID; CHOLESTEROL; GLUTATHIONE; LIVER X RECEPTOR; MYELOPEROXIDASE; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; STREPTOZOCIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; FLUORINATED HYDROCARBON; ORPHAN NUCLEAR RECEPTOR; SULFONAMIDE; TO-901317;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN HOMOGENATE; BRAIN LEVEL; CHOLESTEROL BLOOD LEVEL; COGNITION; CONTROLLED STUDY; DEMENTIA; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HISTOPATHOLOGY; LEARNING DISORDER; LIPID DIET; MALE; MEMORY DISORDER; MORRIS WATER MAZE TEST; MOUSE; MOUSE MODEL; NEUROPATHOLOGY; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; TREATMENT DURATION; AGONISTS; ANIMAL; BRAIN; CHEMICALLY INDUCED; DRUG EFFECTS; ENZYMOLOGY; MAZE TEST; MEMORY; METABOLISM; PATHOLOGY; PSYCHOLOGY;

ACETYLCHOLINESTERASE; ANIMALS; BRAIN; BRAIN CHEMISTRY; DEMENTIA; DIET, HIGH-FAT; FEMALE; HYDROCARBONS, FLUORINATED; MALE; MAZE LEARNING; MEMORY; MICE; ORPHAN NUCLEAR RECEPTORS; STREPTOZOCIN; SULFONAMIDES;

EID: 84908091587     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.03.025     Document Type: Article

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