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Volumn 24, Issue 4, 2013, Pages 307-319

Ameliorative effect of Noni fruit extract on streptozotocin-induced memory impairment in mice

Author keywords

Acetylcholine; Brain derived neurotrophic factor; Memory; Morinda citrifolia; Mouse; Streptozotocin

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ADENOSINE TRIPHOSPHATE; BRAIN DERIVED NEUROTROPHIC FACTOR; KAEMPFEROL; MESSENGER RNA; NEUROPROTECTIVE AGENT; NONI FRUIT EXTRACT; PLANT EXTRACT; QUERCETIN; RUTOSIDE; SCOPOLETIN; STREPTOZOCIN; UNCLASSIFIED DRUG;

EID: 84880592855     PISSN: 09558810     EISSN: 14735849     Source Type: Journal    
DOI: 10.1097/FBP.0b013e3283637a51     Document Type: Article
Times cited : (34)

References (52)
  • 2
    • 73549106545 scopus 로고    scopus 로고
    • Protective effect of curcumin against intracerebral streptozotocin induced impairment in memory and cerebral blood flow
    • Awasthi H, Tota S, Hanif K, Nath C, Shukla R (2010). Protective effect of curcumin against intracerebral streptozotocin induced impairment in memory and cerebral blood flow. Life Sci 86:87-94.
    • (2010) Life Sci , vol.86 , pp. 87-94
    • Awasthi, H.1    Tota, S.2    Hanif, K.3    Nath, C.4    Shukla, R.5
  • 3
    • 77957223169 scopus 로고    scopus 로고
    • Ameliorative effect of quercetin on memory dysfunction in streptozotocin-induced diabetic rats
    • Bhutada P, Mundhada Y, Bansod K, Bhutada C, Tawari S, Dixit P, et al. (2010). Ameliorative effect of quercetin on memory dysfunction in streptozotocin-induced diabetic rats. Neurobiol Learn Mem 94:293-302.
    • (2010) Neurobiol Learn Mem , vol.94 , pp. 293-302
    • Bhutada, P.1    Mundhada, Y.2    Bansod, K.3    Bhutada, C.4    Tawari, S.5    Dixit, P.6
  • 4
    • 0030980379 scopus 로고    scopus 로고
    • A study of the neurotoxic effect of MDMA ('ecstasy') on 5-HT neurones in the brains of mothers and neonates following administration of the drug during pregnancy
    • Colado MI, O'Shea E, Granados R, Misra A, Murray TK, Green AR (1997). A study of the neurotoxic effect of MDMA ('ecstasy') on 5-HT neurones in the brains of mothers and neonates following administration of the drug during pregnancy. Br J Pharmacol 121:827-833.
    • (1997) Br J Pharmacol , vol.121 , pp. 827-833
    • Colado, M.I.1    O'Shea, E.2    Granados, R.3    Misra, A.4    Murray, T.K.5    Green, A.R.6
  • 5
    • 34447565946 scopus 로고    scopus 로고
    • Noni as an anxiolytic and sedative: A mechanism involving its gamma-aminobutyric acidergic effects
    • Deng S, West BJ, Palu AK, Zhou BN, Jensen CJ (2007). Noni as an anxiolytic and sedative: a mechanism involving its gamma-aminobutyric acidergic effects. Phytomedicine 14:517-522.
    • (2007) Phytomedicine , vol.14 , pp. 517-522
    • Deng Swest, B.J.1    Palu, A.K.2    Zhou, B.N.3    Jensen, C.J.4
  • 6
    • 84856496197 scopus 로고    scopus 로고
    • Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease
    • De la Monte SM (2012). Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease. Curr Alzheimer Res 9:35-66.
    • (2012) Curr Alzheimer Res , vol.9 , pp. 35-66
    • De La Monte, S.M.1
  • 7
    • 84855904096 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and Alzheimer's disease: Physiopathology and beyond
    • Diniz BS, Teixeira AL (2011). Brain-derived neurotrophic factor and Alzheimer's disease: physiopathology and beyond. Neuromolecular Med 13:217-222.
    • (2011) Neuromolecular Med , vol.13 , pp. 217-222
    • Diniz, B.S.1    Teixeira, A.L.2
  • 8
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • Ellman GL (1959). Tissue sulfhydryl groups. Arch Biochem Biophys 82:70-77.
    • (1959) Arch Biochem Biophys , vol.82 , pp. 70-77
    • Ellman, G.L.1
  • 9
    • 33750030719 scopus 로고    scopus 로고
    • Opinion on a request from the Commission related to the safety of noni juice (juice of the fruits of Morinda citrifolia)
    • [EFSA] European Food Safety Authority
    • [EFSA] European Food Safety Authority (2006). Opinion on a request from the Commission related to the safety of noni juice (juice of the fruits of Morinda citrifolia). EFSA J 376:1-12.
    • (2006) EFSA J , vol.376 , pp. 1-12
  • 10
    • 79551587282 scopus 로고    scopus 로고
    • ® Morinda citrifolia (noni) fruit puree and concentrate' as a novel food ingredient
    • European Food Safety Authority [EFSA
    • ® Morinda citrifolia (noni) fruit puree and concentrate' as a novel food ingredient. EFSA J 998:1-16.
    • (2009) EFSA J , vol.998 , pp. 1-16
  • 11
    • 70450153028 scopus 로고    scopus 로고
    • European Commission. Scientific Committee on Food. SCF/CS/NF/DOS/18 ADD 2 Final. [Accessed 11 December 2002]
    • ® Juice. SCF/CS/NF/DOS/18 ADD 2 Final. Available at: http://ec.europa.eu/food/fs/sc/scf/ out151-en.pdf [Accessed 11 December 2002].
    • (2002) ® Juice
  • 12
    • 33644530183 scopus 로고    scopus 로고
    • 2003/426/EC: Commission decision of 5 June 2003 authorising the placing on the market of 'noni juice' (juice of the fruit of Morinda citrifolia L.) as a novel food ingredient under regulation (EC)No 258/97 of the European Parliament and of the council
    • European Commission
    • European Commission (2003). 2003/426/EC: Commission decision of 5 June 2003 authorising the placing on the market of 'noni juice' (juice of the fruit of Morinda citrifolia L.) as a novel food ingredient under regulation (EC)No 258/97 of the European Parliament and of the council. Official J Eur Union L 144, p 0012-0012.
    • (2003) Official J Eur Union L , vol.144 , pp. 0012-0012
  • 13
    • 0017112552 scopus 로고
    • Impaired synthesis of acetylcholine in brain accompanying mild hypoxia and hypoglycemia
    • Gibson GE, Blass JP (1976). Impaired synthesis of acetylcholine in brain accompanying mild hypoxia and hypoglycemia. J Neurochem 27:37-42.
    • (1976) J Neurochem , vol.27 , pp. 37-42
    • Gibson, G.E.1    Blass, J.P.2
  • 15
    • 77049106590 scopus 로고    scopus 로고
    • Pharmacological treatment of Alzheimer's disease: Effect of race and demographic variables
    • Hernandez S, McClendon MJ, Zhou XH, Sachs M, Lerner AJ (2010). Pharmacological treatment of Alzheimer's disease: effect of race and demographic variables. J Alzheimers Dis 19:665-672.
    • (2010) J Alzheimers Dis , vol.19 , pp. 665-672
    • Hernandez, S.1    McClendon, M.J.2    Zhou, X.H.3    Sachs, M.4    Lerner, A.J.5
  • 16
    • 82855172099 scopus 로고    scopus 로고
    • The coumarin scopoletin potentiates acetylcholine release from synaptosomes, amplifies hippocampal long-term potentiation and ameliorates anticholinergicand age-impaired memory
    • Hornick A, Lieb A, Vo NP, Rollinger JM, Stuppner H, Prast H (2011). The coumarin scopoletin potentiates acetylcholine release from synaptosomes, amplifies hippocampal long-term potentiation and ameliorates anticholinergicand age-impaired memory. Neuroscience 197:280-292.
    • (2011) Neuroscience , vol.197 , pp. 280-292
    • Hornick, A.1    Lieb, A.2    Vo, N.P.3    Rollinger, J.M.4    Stuppner, H.5    Prast, H.6
  • 17
    • 84863337843 scopus 로고    scopus 로고
    • Alzheimer mechanisms and therapeutic strategies
    • Huang Y, Mucke L (2012). Alzheimer mechanisms and therapeutic strategies. Cell 148:1204-1222.
    • (2012) Cell , vol.148 , pp. 1204-1222
    • Huang, Y.1    Mucke, L.2
  • 18
    • 84861200675 scopus 로고    scopus 로고
    • Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type
    • Javed H, Khan MM, Ahmad A, Vaibhav K, Ahmad ME, Khan A, et al. (2012). Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type. Neuroscience 210:340-352.
    • (2012) Neuroscience , vol.210 , pp. 340-352
    • Javed, H.1    Khan, M.M.2    Ahmad, A.3    Vaibhav, K.4    Ahmad, M.E.5    Khan, A.6
  • 19
    • 49349098548 scopus 로고    scopus 로고
    • Protective effect of rutin against spatial memory impairment induced by trimethyltin in rats
    • Koda T, Kuroda Y, Imai H (2008). Protective effect of rutin against spatial memory impairment induced by trimethyltin in rats. Nutr Res 28:629-634.
    • (2008) Nutr Res , vol.28 , pp. 629-634
    • Koda, T.1    Kuroda, Y.2    Imai, H.3
  • 20
    • 6944230015 scopus 로고    scopus 로고
    • Acetylcholinesterase inhibitors from the twigs of Vaccinium oldhami Miquel
    • Lee JH, Lee KT, Yang JH, Baek NI, Kim DK (2004). Acetylcholinesterase inhibitors from the twigs of Vaccinium oldhami Miquel. Arch Pharm Res 27:53-56.
    • (2004) Arch Pharm Res , vol.27 , pp. 53-56
    • Lee, J.H.1    Lee, K.T.2    Yang, J.H.3    Baek, N.I.4    Kim, D.K.5
  • 22
    • 80051512571 scopus 로고    scopus 로고
    • Neuroprotective effect of kaempferol against a 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced mouse model of Parkinson's disease
    • Li S, Pu XP (2011). Neuroprotective effect of kaempferol against a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease. Biol Pharm Bull 34:1291-1296.
    • (2011) Biol Pharm Bull , vol.34 , pp. 1291-1296
    • Li, S.1    Pu, X.P.2
  • 24
    • 0037925192 scopus 로고    scopus 로고
    • From Polynesian healers to health food stores: Changing perspectives of Morinda citrifolia (Rubiaceae)
    • discussion 120
    • McClatchey W (2002). From Polynesian healers to health food stores: changing perspectives of Morinda citrifolia (Rubiaceae). Integr Cancer Ther 1:110-120, discussion 120.
    • (2002) Integr Cancer Ther , vol.1 , pp. 110-120
    • McClatchey, W.1
  • 25
    • 75849123785 scopus 로고    scopus 로고
    • Protective effect of Morinda citrifolia fruits on beta-amyloid (25-35) induced cognitive dysfunction in mice: An experimental and biochemical study
    • Muralidharan P, Kumar VR, Balamurugan G (2010). Protective effect of Morinda citrifolia fruits on beta-amyloid (25-35) induced cognitive dysfunction in mice: an experimental and biochemical study. Phytother Res 24:252-258.
    • (2010) Phytother Res , vol.24 , pp. 252-258
    • Muralidharan, P.1    Kumar, V.R.2    Balamurugan, G.3
  • 27
    • 79959400409 scopus 로고    scopus 로고
    • Decreased cerebrovascular brain-derived neurotrophic factor-mediated neuroprotection in the diabetic brain
    • Navaratna D, Guo SZ, Hayakawa K, Wang X, Gerhardinger C, Lo EH (2011). Decreased cerebrovascular brain-derived neurotrophic factor-mediated neuroprotection in the diabetic brain. Diabetes 60:1789-1796.
    • (2011) Diabetes , vol.60 , pp. 1789-1796
    • Navaratna, D.1    Guo, S.Z.2    Hayakawa, K.3    Wang, X.4    Gerhardinger, C.5    Lo, E.H.6
  • 28
    • 48249087702 scopus 로고    scopus 로고
    • Coumarin, anthroquinone and stilbene derivatives with anticholinesterase activity
    • Orhan I, Tosun F, Sener B (2008). Coumarin, anthroquinone and stilbene derivatives with anticholinesterase activity. Z Naturforsch C 63:366-370.
    • (2008) Z Naturforsch C , vol.63 , pp. 366-370
    • Orhan, I.1    Tosun, F.2    Sener, B.3
  • 29
    • 83555161656 scopus 로고    scopus 로고
    • Protective effect of fruits of Morinda citrifolia L. On scopolamine induced memory impairment in mice: A behavioral, biochemical and cerebral blood flow study
    • Pachauri SD, Tota S, Khandelwal K, Verma PR, Nath C, Hanif K, et al. (2012). Protective effect of fruits of Morinda citrifolia L. on scopolamine induced memory impairment in mice: a behavioral, biochemical and cerebral blood flow study. J Ethnopharmacol 139:34-41.
    • (2012) J Ethnopharmacol , vol.139 , pp. 34-41
    • Pachauri, S.D.1    Tota, S.2    Khandelwal, K.3    Verma, P.R.4    Nath, C.5    Hanif, K.6
  • 30
    • 37349130599 scopus 로고    scopus 로고
    • The effects of Morinda citrifolia L. (noni) on the immune system: Its molecular mechanisms of action
    • Palu AK, Kim AH, West BJ, Deng S, Jensen J, White L (2008). The effects of Morinda citrifolia L. (noni) on the immune system: its molecular mechanisms of action. J Ethnopharmacol 115:502-506.
    • (2008) J Ethnopharmacol , vol.115 , pp. 502-506
    • Palu, A.K.1    Kim, A.H.2    West, B.J.3    Deng, S.4    Jensen, J.5    White, L.6
  • 31
    • 33750454798 scopus 로고    scopus 로고
    • Chronic administration of pioglitazone attenuates intracerebroventricular streptozotocin induced-memory impairment in rats
    • Pathan AR, Viswanad B, Sonkusare SK, Ramarao P (2006). Chronic administration of pioglitazone attenuates intracerebroventricular streptozotocin induced-memory impairment in rats. Life Sci 79:2209-2216.
    • (2006) Life Sci , vol.79 , pp. 2209-2216
    • Pathan, A.R.1    Viswanad, B.2    Sonkusare, S.K.3    Ramarao, P.4
  • 32
    • 36849033330 scopus 로고    scopus 로고
    • Review of the ethnobotany, chemistry, biological activity and safety of the botanical dietary supplement Morinda citrifolia (noni)
    • Pawlus AD, Kinghorn DA (2007). Review of the ethnobotany, chemistry, biological activity and safety of the botanical dietary supplement Morinda citrifolia (noni). J Pharm Pharmacol 59:1587-1609.
    • (2007) J Pharm Pharmacol , vol.59 , pp. 1587-1609
    • Pawlus, A.D.1    Kinghorn, D.A.2
  • 33
    • 33747286388 scopus 로고    scopus 로고
    • Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: A review of their intracellular targets
    • Ramassamy C (2006). Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets. Eur J Pharmacol 545:51-64.
    • (2006) Eur J Pharmacol , vol.545 , pp. 51-64
    • Ramassamy, C.1
  • 35
    • 9744238799 scopus 로고    scopus 로고
    • Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products
    • Rollinger JM, Hornick A, Langer T, Stuppner H, Prast H (2004). Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products. J Med Chem 47:6248-6254.
    • (2004) J Med Chem , vol.47 , pp. 6248-6254
    • Rollinger, J.M.1    Hornick, A.2    Langer, T.3    Stuppner, H.4    Prast, H.5
  • 37
    • 34249661686 scopus 로고    scopus 로고
    • Gugulipid, an extract of Commiphora whighitii with lipid-lowering properties, has protective effects against streptozotocin-induced memory deficits in mice
    • Saxena G, Singh SP, Pal R, Singh S, Pratap R, Nath C (2007). Gugulipid, an extract of Commiphora whighitii with lipid-lowering properties, has protective effects against streptozotocin-induced memory deficits in mice. Pharmacol Biochem Behav 86:797-805.
    • (2007) Pharmacol Biochem Behav , vol.86 , pp. 797-805
    • Saxena, G.1    Singh, S.P.2    Pal, R.3    Singh, S.4    Pratap, R.5    Nath, C.6
  • 39
    • 0034005306 scopus 로고    scopus 로고
    • Identification of kaempferol as a monoamine oxidase inhibitor and potential Neuroprotectant in extracts of Ginkgo biloba leaves
    • Sloley BD, Urichuk LJ, Morley P, Durkin J, Shan JJ, Pang PK, et al. (2000). Identification of kaempferol as a monoamine oxidase inhibitor and potential Neuroprotectant in extracts of Ginkgo biloba leaves. J Pharm Pharmacol 52:451-459.
    • (2000) J Pharm Pharmacol , vol.52 , pp. 451-459
    • Sloley, B.D.1    Urichuk, L.J.2    Morley, P.3    Durkin, J.4    Shan, J.J.5    Pang, P.K.6
  • 40
    • 33645817531 scopus 로고    scopus 로고
    • Rutin improves glucose homeostasis in streptozotocin diabetic tissues by altering glycolytic and gluconeogenic enzymes
    • Stanley Mainzen Prince P, Kamalakkannan N (2006). Rutin improves glucose homeostasis in streptozotocin diabetic tissues by altering glycolytic and gluconeogenic enzymes. J Biochem Mol Toxicol 20:96-102.
    • (2006) J Biochem Mol Toxicol , vol.20 , pp. 96-102
    • Stanley Mainzen Prince, P.1    Kamalakkannan, N.2
  • 41
    • 17844393868 scopus 로고    scopus 로고
    • Chemical constituents of the fruits of Morinda citrifolia (Noni) and their antioxidant activity
    • Su BN, Pawlus AD, Jung HA, Keller WJ, McLaughlin JL, Kinghorn AD (2005). Chemical constituents of the fruits of Morinda citrifolia (Noni) and their antioxidant activity. J Nat Prod 68:592-595.
    • (2005) J Nat Prod , vol.68 , pp. 592-595
    • Su, B.N.1    Pawlus, A.D.2    Jung, H.A.3    Keller, W.J.4    McLaughlin, J.L.5    Kinghorn, A.D.6
  • 42
    • 79953252716 scopus 로고    scopus 로고
    • Improvement of brain energy metabolism and cholinergic functions contributes to the beneficial effects of silibinin against streptozotocin induced memory impairment
    • Tota S, Kamat PK, Shukla R, Nath C (2011). Improvement of brain energy metabolism and cholinergic functions contributes to the beneficial effects of silibinin against streptozotocin induced memory impairment. Behav Brain Res 221:207-215.
    • (2011) Behav Brain Res , vol.221 , pp. 207-215
    • Tota, S.1    Kamat, P.K.2    Shukla, R.3    Nath, C.4
  • 43
    • 77249130189 scopus 로고    scopus 로고
    • Protective effect of quercetin against intracerebral streptozotocin induced reduction in cerebral blood flow and impairment of memory in mice
    • Tota S, Awasthi H, Kamat PK, Nath C, Hanif K (2010). Protective effect of quercetin against intracerebral streptozotocin induced reduction in cerebral blood flow and impairment of memory in mice. Behav Brain Res 209:73-79.
    • (2010) Behav Brain Res , vol.209 , pp. 73-79
    • Tota, S.1    Awasthi, H.2    Kamat, P.K.3    Nath, C.4    Hanif, K.5
  • 44
    • 84864474059 scopus 로고    scopus 로고
    • Role of central angiotensin receptors in scopolamine-induced impairment in memory, cerebral blood flow, and cholinergic function
    • Tota S, Hanif K, Kamat PK, Najmi AK, Nath C (2012a). Role of central angiotensin receptors in scopolamine-induced impairment in memory, cerebral blood flow, and cholinergic function. Psychopharmacology (Berl) 222:185-202.
    • (2012) Psychopharmacology (Berl) , vol.222 , pp. 185-202
    • Tota, S.1    Hanif, K.2    Kamat, P.K.3    Najmi, A.K.4    Nath, C.5
  • 45
    • 84859929771 scopus 로고    scopus 로고
    • Inhibition of central angiotensin converting enzyme ameliorates scopolamine induced memory impairment in mice: Role of cholinergic neurotransmission, cerebral blood flow and brain energy metabolism
    • Tota S, Nath C, Najmi AK, Shukla R, Hanif K (2012b). Inhibition of central angiotensin converting enzyme ameliorates scopolamine induced memory impairment in mice: role of cholinergic neurotransmission, cerebral blood flow and brain energy metabolism. Behav Brain Res 232:66-76.
    • (2012) Behav Brain Res , vol.232 , pp. 66-76
    • Tota, S.1    Nath, C.2    Najmi, A.K.3    Shukla, R.4    Hanif, K.5
  • 46
    • 61349185049 scopus 로고    scopus 로고
    • Candesartan improves memory decline in mice: Involvement of AT1 receptors in memory deficit induced by intracerebral streptozotocin
    • Tota S, Kamat PK, Awasthi H, Singh N, Raghubir R, Nath C, et al. (2009). Candesartan improves memory decline in mice: involvement of AT1 receptors in memory deficit induced by intracerebral streptozotocin. Behav Brain Res 199:235-240.
    • (2009) Behav Brain Res , vol.199 , pp. 235-240
    • Tota, S.1    Kamat, P.K.2    Awasthi, H.3    Singh, N.4    Raghubir, R.5    Nath, C.6
  • 47
    • 0016637041 scopus 로고
    • Lowry determination of protein in the presence of Triton X-100%
    • Wang C, Smith RL (1975). Lowry determination of protein in the presence of Triton X-100. Anal Biochem 63:414-417.
    • (1975) Anal Biochem , vol.63 , pp. 414-417
    • Wang, C.1    Smith, R.L.2
  • 48
    • 0035680416 scopus 로고    scopus 로고
    • Cancer preventive effect of Morinda citrifolia (Noni)
    • Wang MY, Su C (2001). Cancer preventive effect of Morinda citrifolia (Noni). Ann N Y Acad Sci 952:161-168.
    • (2001) Ann N y Acad Sci , vol.952 , pp. 161-168
    • Wang, M.Y.1    Su, C.2
  • 49
    • 48749100908 scopus 로고    scopus 로고
    • Hepatic protection by noni fruit juice against CCl(4)-induced chronic liver damage in female SD rats
    • Wang MY, Anderson G, Nowicki D, Jensen J (2008). Hepatic protection by noni fruit juice against CCl(4)-induced chronic liver damage in female SD rats. Plant Foods Hum Nutr 63:141-145.
    • (2008) Plant Foods Hum Nutr , vol.63 , pp. 141-145
    • Wang, M.Y.1    Anderson, G.2    Nowicki, D.3    Jensen, J.4
  • 50
    • 0036902226 scopus 로고    scopus 로고
    • Morinda citrifolia (Noni): A literature review and recent advances in Noni research
    • Wang MY, West BJ, Jensen CJ, Nowicki D, Su C, Palu AK, et al. (2002). Morinda citrifolia (Noni): a literature review and recent advances in Noni research. Acta Pharmacol Sin 23:1127-1141.
    • (2002) Acta Pharmacol Sin , vol.23 , pp. 1127-1141
    • Wang Mywest, B.J.1    Jensen, C.J.2    Nowicki, D.3    Su, C.4    Palu, A.K.5
  • 52
    • 80053143566 scopus 로고    scopus 로고
    • Anti-diabetic effects of a kaempferol glycosiderich fraction from unripe soybean (Edamame, Glycine max L. Merrill. 'Jindai') leaves on KK-A(y) mice
    • Zang Y, Sato H, Igarashi K (2011). Anti-diabetic effects of a kaempferol glycosiderich fraction from unripe soybean (Edamame, Glycine max L. Merrill. 'Jindai') leaves on KK-A(y) mice. Biosci Biotechnol Biochem. 75:pp. 1677-1684.
    • (2011) Biosci Biotechnol Biochem , vol.75 , pp. 1677-1684
    • Zang, Y.1    Sato, H.2    Igarashi, K.3


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