-
1
-
-
1842734659
-
The source of cerebral insulin
-
Banks WA (2004) The source of cerebral insulin. Eur J Pharmacol 490:5-12
-
(2004)
Eur. J. Pharmacol.
, vol.490
, pp. 5-12
-
-
Banks, W.A.1
-
3
-
-
0029820954
-
Changes of activity and isoenzyme pattern of phosphofructokinase in the brains of patients with Alzheimer's disease
-
Bigl M, Bleyl AD, Zedlick D, Arendt T, Bigl V, Eschrich K (1996) Changes of activity and isoenzyme pattern of phosphofructokinase in the brains of patients with Alzheimer's disease. J Neurochem 67:1164-1171
-
(1996)
J. Neurochem.
, vol.67
, pp. 1164-1171
-
-
Bigl, M.1
Bleyl, A.D.2
Zedlick, D.3
Arendt, T.4
Bigl, V.5
Eschrich, K.6
-
4
-
-
0032983691
-
Activities of key glycolytic enzymes in the brains of patients with Alzheimer's disease
-
Bigl M, Brüuckner MK, Arendt T, Bigl V, Eschrich K (1999) Activities of key glycolytic enzymes in the brains of patients with Alzheimer's disease. J Neural Transm 100:499-511
-
(1999)
J. Neural. Transm.
, vol.100
, pp. 499-511
-
-
Bigl, M.1
Brüuckner, M.K.2
Arendt, T.3
Bigl, V.4
Eschrich, K.5
-
5
-
-
0034728597
-
Altered phosphofruktokinase mRNA levels but unchanged isoenzyme pattern in brains from patients with Alzheimer's disease
-
Bigl M, Beck M, Bleyl AD, Bigl V, Eschrich K (2000) Altered phosphofruktokinase mRNA levels but unchanged isoenzyme pattern in brains from patients with Alzheimer's disease. Mol Brain Res 76:411-414
-
(2000)
Mol. Brain Res.
, vol.76
, pp. 411-414
-
-
Bigl, M.1
Beck, M.2
Bleyl, A.D.3
Bigl, V.4
Eschrich, K.5
-
6
-
-
0027518372
-
Spatial learning deficit and reduced hippocampal ChAT activity in rats after an icv injection of streptozotocin
-
Blokland A, Jolles J (1993) Spatial learning deficit and reduced hippocampal ChAT activity in rats after an icv injection of streptozotocin. Pharmacol Biochem Behav 44:491-494
-
(1993)
Pharmacol. Biochem. Behav.
, vol.44
, pp. 491-494
-
-
Blokland, A.1
Jolles, J.2
-
7
-
-
33845293444
-
Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease
-
Brooks WM, Lynch PJ, Ingle CC, Hatton A, Emson PC, Faull RLM, Starkey MP (2007) Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease. Brain Res 1127:127-135
-
(2007)
Brain Res.
, vol.1127
, pp. 127-135
-
-
Brooks, W.M.1
Lynch, P.J.2
Ingle, C.C.3
Hatton, A.4
Emson, P.C.5
Faull, R.L.M.6
Starkey, M.P.7
-
8
-
-
0024856331
-
31P-NMR profiles of Alzheimer disease and multiple subcortical infarct dementia
-
31P-NMR profiles of Alzheimer disease and multiple subcortical infarct dementia. Neurology 39:1423-1427
-
(1989)
Neurology
, vol.39
, pp. 1423-1427
-
-
Brown, G.G.1
Levine, S.R.2
Gorell, J.M.3
Pettegrew, J.W.4
Gdowski, J.E.5
Bueri, J.A.6
Helpern, J.A.7
Welch, K.M.A.8
-
9
-
-
18244390483
-
Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
-
Bubber P, Haroutunian V, Fisch G, Blass JP, Gibson GE (2005) Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications. Ann Neurol 57:695-703
-
(2005)
Ann. Neurol.
, vol.57
, pp. 695-703
-
-
Bubber, P.1
Haroutunian, V.2
Fisch, G.3
Blass, J.P.4
Gibson, G.E.5
-
10
-
-
0025650037
-
Thiamine-dependent enzyme changes in temporal cortex of patients with Alzheimer's disease
-
Butterworth RF, Besnard AM (1990) Thiamine-dependent enzyme changes in temporal cortex of patients with Alzheimer's disease. Metab Brain Dis 5:179-184
-
(1990)
Metab. Brain Dis.
, vol.5
, pp. 179-184
-
-
Butterworth, R.F.1
Besnard, A.M.2
-
11
-
-
0028802746
-
A hierarchy of ATP-consuming processes in mammalian cells
-
Buttgereit F, Brand MD (1995) A hierarchy of ATP-consuming processes in mammalian cells. Biochem J 312:163-167
-
(1995)
Biochem. J.
, vol.312
, pp. 163-167
-
-
Buttgereit, F.1
Brand, M.D.2
-
12
-
-
33748755428
-
Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: Relevance to Alzheimer's disease
-
de la Monte S, Tong M, Lester-Coll N, Plater Jr M, Wands JR (2006) Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: Relevance to Alzheimer's disease. J Alzheimers Dis 10:89-109
-
(2006)
J. Alzheimers Dis.
, vol.10
, pp. 89-109
-
-
De La Monte, S.1
Tong, M.2
Lester-Coll, N.3
Plater Jr., M.4
Wands, J.R.5
-
13
-
-
0028310417
-
Insulin gene expression and insulin synthesis in mammalian neuronal cells
-
Devaskar SU, Giddings SJ, Rajakumar PA, Carnaghi LR, Menon RK, Zahm DS (1994) Insulin gene expression and insulin synthesis in mammalian neuronal cells. J Biol Chem 269:8445-8454
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8445-8454
-
-
Devaskar, S.U.1
Giddings, S.J.2
Rajakumar, P.A.3
Carnaghi, L.R.4
Menon, R.K.5
Zahm, D.S.6
-
14
-
-
0028598190
-
Intracerebroventricular injection of streptozotocin induces discrete local changes in cerebral glucose utilization in rats
-
Duelli R, Schröck H, Kuschinsky W, Hoyer S (1994) Intracerebroventricular injection of streptozotocin induces discrete local changes in cerebral glucose utilization in rats. Int J Dev Neurosci 12:737-743
-
(1994)
Int. J. Dev. Neurosci.
, vol.12
, pp. 737-743
-
-
Duelli, R.1
Schröck, H.2
Kuschinsky, W.3
Hoyer, S.4
-
15
-
-
4143138616
-
Association of elevated phospho-tau levels with Alzheimer-typical 18F-Fluoro-2-deoxy-D-glucose positron emission tomography findings in patients with mild cognitive impairment
-
Fellgiebel A, Siesmeier T, Scheurich A, Winterer G, Bartenstein P, Schmidt LG, Müuller MJ (2004) Association of elevated phospho-tau levels with Alzheimer-typical 18F-Fluoro-2-deoxy-D-glucose positron emission tomography findings in patients with mild cognitive impairment. Biol Psychiatry 56:279-283
-
(2004)
Biol. Psychiatry
, vol.56
, pp. 279-283
-
-
Fellgiebel, A.1
Siesmeier, T.2
Scheurich, A.3
Winterer, G.4
Bartenstein, P.5
Schmidt, L.G.6
Müuller, M.J.7
-
16
-
-
15444339756
-
Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease
-
Frölich L, Blum-Degen D, Bernstein HG, Engelsberger S, Humrich J, Laufer S, Muschner D, Thalheimer A, Turk A, Hoyer S, Zochling R, Boissl KW, Jellinger K, Riederer P (1998) Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease. J Neural Transm 105:423-438
-
(1998)
J. Neural. Transm.
, vol.105
, pp. 423-438
-
-
Frölich, L.1
Blum-Degen, D.2
Bernstein, H.G.3
Engelsberger, S.4
Humrich, J.5
Laufer, S.6
Muschner, D.7
Thalheimer, A.8
Turk, A.9
Hoyer, S.10
Zochling, R.11
Boissl, K.W.12
Jellinger, K.13
Riederer, P.14
-
17
-
-
0037303635
-
Brain insulin: Regulation, mechanism of action and functions
-
Gerozissis K (2003) Brain insulin: Regulation, mechanism of action and functions. Cell Mol Neurobiol 23:1-25
-
(2003)
Cell. Mol. Neurobiol.
, vol.23
, pp. 1-25
-
-
Gerozissis, K.1
-
18
-
-
0016741395
-
Decreased synthesis of acetylcholine accompanying impaired oxidation of pyruvic acid in rat brain minces
-
Gibson GE, Jope R, Blass JP (1975) Decreased synthesis of acetylcholine accompanying impaired oxidation of pyruvic acid in rat brain minces. Biochem J 148:17-23
-
(1975)
Biochem. J.
, vol.148
, pp. 17-23
-
-
Gibson, G.E.1
Jope, R.2
Blass, J.P.3
-
19
-
-
0026531943
-
Changes in tyrosine phosphorylation of insulin receptors and a 170, 000 molecular weight nonreceptor protein in vivo in skeletal muscle of streptozotocin-induced diabetic rats: Effects of insulin and glucose
-
Giorgino F, Chen JH, Smith RJ (1992) Changes in tyrosine phosphorylation of insulin receptors and a 170, 000 molecular weight nonreceptor protein in vivo in skeletal muscle of streptozotocin-induced diabetic rats: Effects of insulin and glucose. Endocrinology 130:1433-1444
-
(1992)
Endocrinology
, vol.130
, pp. 1433-1444
-
-
Giorgino, F.1
Chen, J.H.2
Smith, R.J.3
-
20
-
-
0014011226
-
Effects of changes in brain metabolism on the levels of critic cycle intermediates
-
Goldberg ND, Passonneau JV, Lowry OH (1966) Effects of changes in brain metabolism on the levels of critic cycle intermediates. J Biol Chem 241:3997-4003
-
(1966)
J. Biol. Chem.
, vol.241
, pp. 3997-4003
-
-
Goldberg, N.D.1
Passonneau, J.V.2
Lowry, O.H.3
-
21
-
-
33646002650
-
Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlycNAcylation
-
Gong CX, Liu F, Grundke-Iqbal I, Iqbal K (2006) Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlycNAcylation. J Alzheimers Dis 9:1-12
-
(2006)
J. Alzheimers Dis.
, vol.9
, pp. 1-12
-
-
Gong, C.X.1
Liu, F.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
22
-
-
33747399431
-
Gene expression alterations in brain areas of intracerebroventricular streptozotocin treated rat
-
Grüunblatt E, Koutsilieri E, Hoyer S, Riederer P (2000) Gene expression alterations in brain areas of intracerebroventricular streptozotocin treated rat. J Alzheimers Dis 9:261-271
-
(2000)
J. Alzheimers Dis.
, vol.9
, pp. 261-271
-
-
Grüunblatt, E.1
Koutsilieri, E.2
Hoyer, S.3
Riederer, P.4
-
23
-
-
1542313775
-
Gene expression profile in stroptozotocin rat model for sporadic Alzheimer's disease
-
Grüunblatt E, Hoyer S, Riederer P (2004) Gene expression profile in stroptozotocin rat model for sporadic Alzheimer's disease. J Neural Transm 111:367-386
-
(2004)
J. Neural. Transm.
, vol.111
, pp. 367-386
-
-
Grüunblatt, E.1
Hoyer, S.2
Riederer, P.3
-
24
-
-
34247324303
-
Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau-protein
-
Grüunblatt E, Salkovic-Petrisic M, Osmanovic J, Riederer P, Hoyer S (2007) Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau-protein. J Neurochem 101:757-770
-
(2007)
J. Neurochem.
, vol.101
, pp. 757-770
-
-
Grüunblatt, E.1
Salkovic-Petrisic, M.2
Osmanovic, J.3
Riederer, P.4
Hoyer, S.5
-
26
-
-
0030943923
-
Dynamic O-linked glycosylation of nuclear and cytoskeletal proteins
-
Hart GW (1997) Dynamic O-linked glycosylation of nuclear and cytoskeletal proteins. Ann Rev Biochem 66:315-335
-
(1997)
Ann. Rev. Biochem.
, vol.66
, pp. 315-335
-
-
Hart, G.W.1
-
27
-
-
0026754136
-
Nerve growth factor and choline acetyltransferase activity level in rat brain following experimental impairment of cerebral glucose and energy metabolism
-
Hellweg R, Nitsch R, Hock C, Jaksch M, Hoyer S (1992) Nerve growth factor and choline acetyltransferase activity level in rat brain following experimental impairment of cerebral glucose and energy metabolism. J Neurosci Res 31:479-486
-
(1992)
J. Neurosci. Res.
, vol.31
, pp. 479-486
-
-
Hellweg, R.1
Nitsch, R.2
Hock, C.3
Jaksch, M.4
Hoyer, S.5
-
28
-
-
0022510796
-
Autoradiographic localization of insulin receptors in rat brain: Prominence in olfactory and limbic areas
-
Hill JM, Lesniak MA, Pert CB, Roth J (1986) Autoradiographic localization of insulin receptors in rat brain: prominence in olfactory and limbic areas. Neuroscience 17:1127-1138
-
(1986)
Neuroscience
, vol.17
, pp. 1127-1138
-
-
Hill, J.M.1
Lesniak, M.A.2
Pert, C.B.3
Roth, J.4
-
29
-
-
0028966818
-
Increased levels of tau-protein in cerebrospinal fluid of patients with Alzheimer's disease-correlation with degree of cognitive impairment
-
Hock C, Golombowski S, Naser W, Müuller-Spahn F (1995) Increased levels of tau-protein in cerebrospinal fluid of patients with Alzheimer's disease-correlation with degree of cognitive impairment. Ann Neurol 37:414-415
-
(1995)
Ann. Neurol.
, vol.37
, pp. 414-415
-
-
Hock, C.1
Golombowski, S.2
Naser, W.3
Müuller-Spahn, F.4
-
30
-
-
0026781603
-
Oxidative energy metabolism in Alzheimer brain. Studies in early-onset and late-onset cases
-
Hoyer S (1992) Oxidative energy metabolism in Alzheimer brain. Studies in early-onset and late-onset cases. Mol Chem Neuropathol 16:207-224
-
(1992)
Mol. Chem. Neuropathol.
, vol.16
, pp. 207-224
-
-
Hoyer, S.1
-
31
-
-
0031928535
-
Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis
-
Hoyer S (1998) Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis. J Neural Transm 105:415-422
-
(1998)
J. Neural. Transm.
, vol.105
, pp. 415-422
-
-
Hoyer, S.1
-
32
-
-
1842785179
-
Glucose metabolism and insulin signal transduction in Alzheimer disease
-
Hoyer S (2004) Glucose metabolism and insulin signal transduction in Alzheimer disease. Eur J Pharmacol 490:115-125
-
(2004)
Eur. J. Pharmacol.
, vol.490
, pp. 115-125
-
-
Hoyer, S.1
-
34
-
-
0022598348
-
Ischemia and the aging brain. Studies on glucose and energy metabolism in rat cerebral cortex
-
Hoyer S, Krier C (1986) Ischemia and the aging brain. Studies on glucose and energy metabolism in rat cerebral cortex. Neurobiol Aging 7:23-29
-
(1986)
Neurobiol. Aging
, vol.7
, pp. 23-29
-
-
Hoyer, S.1
Krier, C.2
-
35
-
-
0016260870
-
The effect of stepwise arterial hypotension on blood flow and oxidative metabolism of the brain
-
Hoyer S, Hamer J, Alberti E, Stoeckel H, Weinhardt F (1974) The effect of stepwise arterial hypotension on blood flow and oxidative metabolism of the brain. Pflüugers Arch 351:161-172
-
(1974)
Pflüugers Arch.
, vol.351
, pp. 161-172
-
-
Hoyer, S.1
Hamer, J.2
Alberti, E.3
Stoeckel, H.4
Weinhardt, F.5
-
36
-
-
1942500867
-
Relationship between cerebral energy metabolism in parietotemporal cortex and hippocampus and mental activity during aging in rats
-
Hoyer S, Lannert H, Latteier E, Meisel T (2004) Relationship between cerebral energy metabolism in parietotemporal cortex and hippocampus and mental activity during aging in rats. J Neural Transm 111:575-589
-
(2004)
J. Neural. Transm.
, vol.111
, pp. 575-589
-
-
Hoyer, S.1
Lannert, H.2
Latteier, E.3
Meisel, T.4
-
37
-
-
0014772292
-
The effect of arterial hypotension upon the lactate, pyruvate and bicarbonate concentration of the brain tissue and cisternal CSF, and upon the tissue concentrations of phosphocreatine and adenine nucleotides in anesthetized rats
-
Kaasik AE, Nilsson L, Siesjö BK (1970) The effect of arterial hypotension upon the lactate, pyruvate and bicarbonate concentration of the brain tissue and cisternal CSF, and upon the tissue concentrations of phosphocreatine and adenine nucleotides in anesthetized rats. Acta Physiol Scand 78:448-458
-
(1970)
Acta Physiol. Scand.
, vol.78
, pp. 448-458
-
-
Kaasik, A.E.1
Nilsson, L.2
Siesjö, B.K.3
-
38
-
-
0021745904
-
Decreased autophoysphorylation of the insulin receptor-kinase in streptozotocindiabetic rats
-
Kadowaki T, Kasuga M, Akanuma Y, Ezaki O, Takaku F (1984) Decreased autophoysphorylation of the insulin receptor-kinase in streptozotocindiabetic rats. J Biol Chem 259:14208-14216
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 14208-14216
-
-
Kadowaki, T.1
Kasuga, M.2
Akanuma, Y.3
Ezaki, O.4
Takaku, F.5
-
39
-
-
0014558933
-
The regulation of extra-and intracellular acid-base parameters in the rat brain during hyper-and hypocapnia
-
Kjäallquist A, Nardini M, Siesjö BK (1969) The regulation of extra-and intracellular acid-base parameters in the rat brain during hyper-and hypocapnia. Acta Physiol Scand 76:485-494
-
(1969)
Acta Physiol. Scand.
, vol.76
, pp. 485-494
-
-
Kjäallquist, A.1
Nardini, M.2
Siesjö, B.K.3
-
40
-
-
0029257151
-
Nitric oxide generation during cellular metabolization of the diabetogenic N-methyl-N-nitroso-urea streptozotocin contributes to islet cell DNA damage
-
Kröncke KD, Fehsel K, Sommer A, Rodriguez ML, Kolb-Bachofen V (1995) Nitric oxide generation during cellular metabolization of the diabetogenic N-methyl-N-nitroso-urea streptozotocin contributes to islet cell DNA damage. Biol Chem Hoppe-Seyler 376:179-185
-
(1995)
Biol. Chem. Hoppe-seyler
, vol.376
, pp. 179-185
-
-
Kröncke, K.D.1
Fehsel, K.2
Sommer, A.3
Rodriguez, M.L.4
Kolb-Bachofen, V.5
-
41
-
-
0025092112
-
Streptozotocin and alloxan produce alterations in rat brain monoamines independently of pancreatic beta cell destruction
-
Lackovic Z, Salkovic M (1990) Streptozotocin and alloxan produce alterations in rat brain monoamines independently of pancreatic beta cell destruction. Life Sci 46:49-54
-
(1990)
Life Sci.
, vol.46
, pp. 49-54
-
-
Lackovic, Z.1
Salkovic, M.2
-
42
-
-
0021913950
-
Differential effects of monovalent, divalent and trivalent metal ions on rat brain hexokinase
-
Lai JCK, Baker A, Carlson K, Blass JP (1985) Differential effects of monovalent, divalent and trivalent metal ions on rat brain hexokinase. Comp Biochem Physiol 80:291-294
-
(1985)
Comp. Biochem. Physiol.
, vol.80
, pp. 291-294
-
-
Lai, J.C.K.1
Baker, A.2
Carlson, K.3
Blass, J.P.4
-
43
-
-
0031797937
-
Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats
-
Lannert H, Hoyer S (1998) Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats. Behav Neurosci 112:1199-1208
-
(1998)
Behav. Neurosci.
, vol.112
, pp. 1199-1208
-
-
Lannert, H.1
Hoyer, S.2
-
44
-
-
0031593920
-
Effects of estradiol (-17β) on learning, memory and cerebral energy metabolism in male rats after intracerebroventricular administration of streptozotocin
-
Lannert H, Wirtz P, Schuhmann V, Galmbacher R (1998) Effects of estradiol (-17β) on learning, memory and cerebral energy metabolism in male rats after intracerebroventricular administration of streptozotocin. J Neural Transm 105:1045-1063
-
(1998)
J. Neural. Transm.
, vol.105
, pp. 1045-1063
-
-
Lannert, H.1
Wirtz, P.2
Schuhmann, V.3
Galmbacher, R.4
-
45
-
-
0019731594
-
Energy-metabolizing enzymes in the brain regions of adult and aging rats
-
Leong SF, Lai JCK, Lim L, Clark JB (1981) Energy-metabolizing enzymes in the brain regions of adult and aging rats. J Neurochem 37:1548-1556
-
(1981)
J. Neurochem.
, vol.37
, pp. 1548-1556
-
-
Leong, S.F.1
Lai, J.C.K.2
Lim, L.3
Clark, J.B.4
-
46
-
-
33645960672
-
Intracerebral streptozotocin model of type 3 diabetes: Relevance to sporadic Alzheimer's disease
-
Lester-Coll N, Rivera EJ, Soscia SJ, Doiron K, Wands JR, de la Monte SM (2006) Intracerebral streptozotocin model of type 3 diabetes: Relevance to sporadic Alzheimer's disease. J Alzheimers Dis 9:13-33
-
(2006)
J. Alzheimers Dis.
, vol.9
, pp. 13-33
-
-
Lester-Coll, N.1
Rivera, E.J.2
Soscia, S.J.3
Doiron, K.4
Wands, J.R.5
De La Monte, S.M.6
-
47
-
-
0016116659
-
Changes in carbohydrate substrates, amino acids and ammonia in the brain during insulin-induced hypoglycaemia
-
Lewis LD, Ljunggren B, Norberg K, Siesjö BK (1974) Changes in carbohydrate substrates, amino acids and ammonia in the brain during insulin-induced hypoglycaemia. J Neurochem 23:659-671
-
(1974)
J. Neurochem.
, vol.23
, pp. 659-671
-
-
Lewis, L.D.1
Ljunggren, B.2
Norberg, K.3
Siesjö, B.K.4
-
48
-
-
3242739968
-
O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease
-
Liu F, Iqbal K, Grundke-Iqbal I, Hart GW, Gong CX (2004) O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease. Proc Natl Acad Sci USA 101:10804-10809
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10804-10809
-
-
Liu, F.1
Iqbal, K.2
Grundke-Iqbal, I.3
Hart, G.W.4
Gong, C.X.5
-
51
-
-
0027332651
-
Brain a-ketoglutarate dehydrogenase complex activity in Alzheimer's disease
-
Mastrogiacomo F, Bergeron C, Kish SJ (1983) Brain a-ketoglutarate dehydrogenase complex activity in Alzheimer's disease. J Neurochem 61:2007-2014
-
(1983)
J. Neurochem.
, vol.61
, pp. 2007-2014
-
-
Mastrogiacomo, F.1
Bergeron, C.2
Kish, S.J.3
-
52
-
-
33750486501
-
Alois Alzheimer revisited: Differences in origin of the disease carrying his name
-
Maurer K, Hoyer S (2006) Alois Alzheimer revisited: differences in origin of the disease carrying his name. J Neural Transm 113:1645-1658
-
(2006)
J. Neural. Transm.
, vol.113
, pp. 1645-1658
-
-
Maurer, K.1
Hoyer, S.2
-
53
-
-
0024990390
-
Effects of changes in peripheral and cerebral glucose metabolism on locomotor activity learning and memory in adult male rats
-
Mayer G, Nitsch R, Hoyer S (1990) Effects of changes in peripheral and cerebral glucose metabolism on locomotor activity learning and memory in adult male rats. Brain Res 532:95-100
-
(1990)
Brain Res.
, vol.532
, pp. 95-100
-
-
Mayer, G.1
Nitsch, R.2
Hoyer, S.3
-
54
-
-
0032973711
-
Inhibition of cholesterol production but not of nonsterol isoprenoid products induces neuronal cell death
-
Michikawa M, Yanagisawa K (1999) Inhibition of cholesterol production but not of nonsterol isoprenoid products induces neuronal cell death. J Neurochem 72:2278-2285
-
(1999)
J. Neurochem.
, vol.72
, pp. 2278-2285
-
-
Michikawa, M.1
Yanagisawa, K.2
-
55
-
-
0028008696
-
Clinical deterioration in probable Alzheimer's disease correlates with progressive metabolic impairment of association areas
-
Mielke R, Herholz K, Grond M, Heiss WD (1994) Clinical deterioration in probable Alzheimer's disease correlates with progressive metabolic impairment of association areas. Dementia 5:36-41
-
(1994)
Dementia
, vol.5
, pp. 36-41
-
-
Mielke, R.1
Herholz, K.2
Grond, M.3
Heiss, W.D.4
-
56
-
-
0030874251
-
Metabolic reduction in the posterior cingulated cortex in very early Alzheimer's disease
-
Minoshima S, Giordani B, Berent S, Frey KA, Foster NL, Kuhl DE (1997) Metabolic reduction in the posterior cingulated cortex in very early Alzheimer's disease. Ann Neurol 42:85-94
-
(1997)
Ann. Neurol.
, vol.42
, pp. 85-94
-
-
Minoshima, S.1
Giordani, B.2
Berent, S.3
Frey, K.A.4
Foster, N.L.5
Kuhl, D.E.6
-
57
-
-
0344097391
-
Streptozotocin increases free fatty acids and decreases phospholipids in rat brain
-
Muller D, Nitsch RM, Wurtman RJ, Hoyer S (1998) Streptozotocin increases free fatty acids and decreases phospholipids in rat brain. J Neural Transm 105:1271-1281
-
(1998)
J. Neural. Transm.
, vol.105
, pp. 1271-1281
-
-
Muller, D.1
Nitsch, R.M.2
Wurtman, R.J.3
Hoyer, S.4
-
58
-
-
0025737376
-
Local action of the diabetogenic drug, streptozotocin, on glucose and energy metabolism in rat brain cortex
-
Nitsch R, Hoyer S (1991) Local action of the diabetogenic drug, streptozotocin, on glucose and energy metabolism in rat brain cortex. Neurosci Lett 128:199-202
-
(1991)
Neurosci. Lett.
, vol.128
, pp. 199-202
-
-
Nitsch, R.1
Hoyer, S.2
-
59
-
-
0008685722
-
Impairment of cerebral glucose metabolism parallels learning and memory dysfunction after intracerebral streptozotocin
-
Maurer K, Riederer P, Beckmann H eds, Springer, Wien New York
-
Nitsch RM, Mayer G, Galmbacher R, Galmbacher G, Apell V, Hoyer S (1990) Impairment of cerebral glucose metabolism parallels learning and memory dysfunction after intracerebral streptozotocin. In: Maurer K, Riederer P, Beckmann H (eds) Alzheimer's disease. Epidermiology, neuropathology, neurochemistry, and clinics. Springer, Wien New York, pp 201-209
-
(1990)
Alzheimer's Disease. Epidermiology, Neuropathology, Neurochemistry, and Clinics
, pp. 201-209
-
-
Nitsch, R.M.1
Mayer, G.2
Galmbacher, R.3
Galmbacher, G.4
Apell, V.5
Hoyer, S.6
-
60
-
-
0017233305
-
Oxidative metabolism of the cerebral cortex of the rat in insulin-induced hypoglycaemia
-
Norberg K, Siesjö BK (1976) Oxidative metabolism of the cerebral cortex of the rat in insulin-induced hypoglycaemia. J Neurochem 26:345-352
-
(1976)
J. Neurochem.
, vol.26
, pp. 345-352
-
-
Norberg, K.1
Siesjö, B.K.2
-
61
-
-
0034938160
-
Cognitive effects of insulin in the central nervous system
-
Park CR (2001) Cognitive effects of insulin in the central nervous system. Neurosci Biobehav Rev 25:311-323
-
(2001)
Neurosci. Biobehav Rev.
, vol.25
, pp. 311-323
-
-
Park, C.R.1
-
62
-
-
0018826694
-
Coenzyme A-acetylating enzymes in Alzheimer's disease: Possible cholinergic "compartment" of pyruvate dehydrogenase
-
Perry EK, Perry RG, Tomlinson BE, Blessed G, Gibson PH (1980) Coenzyme A-acetylating enzymes in Alzheimer's disease: possible cholinergic "compartment" of pyruvate dehydrogenase. Neurosci Lett 18:105-110
-
(1980)
Neurosci. Lett.
, vol.18
, pp. 105-110
-
-
Perry, E.K.1
Perry, R.G.2
Tomlinson, B.E.3
Blessed, G.4
Gibson, P.H.5
-
63
-
-
0027304893
-
Action of the diabetogenic drug streptozotocin on glycolytic and glycogenolytic metabolism in adult rat brain cortex and hippocampus
-
Plaschke K, Hoyer S (1993) Action of the diabetogenic drug streptozotocin on glycolytic and glycogenolytic metabolism in adult rat brain cortex and hippocampus. Int J Dev Neurosci 11:477-483
-
(1993)
Int. J. Dev. Neurosci.
, vol.11
, pp. 477-483
-
-
Plaschke, K.1
Hoyer, S.2
-
64
-
-
17844377864
-
Insulin signalling in the central nervous system. A critical role in metabolic homeostasis and disease. From C elegant to humans
-
Porte Jr D, Baskin DG, Schwartz MW (2005) Insulin signalling in the central nervous system. A critical role in metabolic homeostasis and disease. From C elegant to humans. Diabetes 54:1264-1276
-
(2005)
Diabetes
, vol.54
, pp. 1264-1276
-
-
Porte Jr., D.1
Baskin, D.G.2
Schwartz, M.W.3
-
65
-
-
0033009497
-
Cognitive performance and biochemical markers in septum, hippocampus and striatum of rats after an icv injection of streptozotocin: A correlation analysis
-
Prickaerts J, Fahring T, Blokland A (1999) Cognitive performance and biochemical markers in septum, hippocampus and striatum of rats after an icv injection of streptozotocin: a correlation analysis. Behav Brain Res 102:73-88
-
(1999)
Behav. Brain Res.
, vol.102
, pp. 73-88
-
-
Prickaerts, J.1
Fahring, T.2
Blokland, A.3
-
66
-
-
0023876591
-
Insulin receptors in the brain: Structural and physiological characterization
-
Raizada MK, Shemer J, Judkins JH, Clarke DW, Masters BA, Le Roith D (1988) Insulin receptors in the brain: structural and physiological characterization. Neurochem Res 13:297-303
-
(1988)
Neurochem. Res.
, vol.13
, pp. 297-303
-
-
Raizada, M.K.1
Shemer, J.2
Judkins, J.H.3
Clarke, D.W.4
Masters, B.A.5
Le Roith, D.6
-
67
-
-
33644591150
-
Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetylcholine
-
Rivera EJ, Goldin A, Fulmer N, Tavares R, Wands JR, de la Monte SM (2005) Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetylcholine. J Alzheimers Dis 8:247-268
-
(2005)
J. Alzheimers Dis.
, vol.8
, pp. 247-268
-
-
Rivera, E.J.1
Goldin, A.2
Fulmer, N.3
Tavares, R.4
Wands, J.R.5
De La Monte, S.M.6
-
68
-
-
0025719976
-
Two novel kinases phosphorylate tau and the KSP site of heavy neurofilament subunits in high stoichiometric ratios
-
Röder HM, Ingram VM (1991) Two novel kinases phosphorylate tau and the KSP site of heavy neurofilament subunits in high stoichiometric ratios. J Neurosci 11:3325-3342
-
(1991)
J. Neurosci.
, vol.11
, pp. 3325-3342
-
-
Röder, H.M.1
Ingram, V.M.2
-
69
-
-
0347274349
-
Cerebral metabolism of isotopic glucose in normal brain subjects
-
Sacks W (1957) Cerebral metabolism of isotopic glucose in normal brain subjects. J Appl Physiol 10:37-44
-
(1957)
J. Appl. Physiol.
, vol.10
, pp. 37-44
-
-
Sacks, W.1
-
70
-
-
33645100144
-
Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway
-
Salkovic-Petrisic M, Tribl F, Schmidt M, Hoyer S, Riederer P (2006) Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway. J Neurochem 96:1005-1015
-
(2006)
J. Neurochem.
, vol.96
, pp. 1005-1015
-
-
Salkovic-Petrisic, M.1
Tribl, F.2
Schmidt, M.3
Hoyer, S.4
Riederer, P.5
-
71
-
-
0026780273
-
Developmental regulation of insulin in the mammalian central nervous system
-
Schechter R, Whitmire J, Holtzclaw L, George M, Harlow R, Devaskar SU (1992) Developmental regulation of insulin in the mammalian central nervous system. Brain Res 582:27-37
-
(1992)
Brain Res.
, vol.582
, pp. 27-37
-
-
Schechter, R.1
Whitmire, J.2
Holtzclaw, L.3
George, M.4
Harlow, R.5
Devaskar, S.U.6
-
72
-
-
0030583645
-
Prepoinsulin I and II mRNAs and insulin electron microscopic immunoreaction are present within the rat fetal nervous system
-
Schechter R, Beju D, Gaffney T, Schaefer F, Whetsell L (1996) Prepoinsulin I and II mRNAs and insulin electron microscopic immunoreaction are present within the rat fetal nervous system. Brain Res 736:16-27
-
(1996)
Brain Res.
, vol.736
, pp. 16-27
-
-
Schechter, R.1
Beju, D.2
Gaffney, T.3
Schaefer, F.4
Whetsell, L.5
-
73
-
-
0013359320
-
Cerebrospinal fluid tau levels in Alzheimer's disease are elevated when compared with vascular dementia but do not correlate with measures of cerebral atrophy
-
Schönknecht P, Pantel J, Hartmann T, Werle E, Volkmann M, Essig M, Amann M, Zanabili N, Bardenheuer H, Hunt A, Schröder J (2003) Cerebrospinal fluid tau levels in Alzheimer's disease are elevated when compared with vascular dementia but do not correlate with measures of cerebral atrophy. Psychiatr Res 120:231-238
-
(2003)
Psychiatr. Res.
, vol.120
, pp. 231-238
-
-
Schönknecht, P.1
Pantel, J.2
Hartmann, T.3
Werle, E.4
Volkmann, M.5
Essig, M.6
Amann, M.7
Zanabili, N.8
Bardenheuer, H.9
Hunt, A.10
Schröder, J.11
-
75
-
-
0026786571
-
Tissue specific regulation of insulin receptor mRNA levels in rats with STZ-induced diabetes mellitus
-
Sechi LA, Griffin CA, Grady EF, Grunfeld C, Kalinyak JE, Schambelan M (1992) Tissue specific regulation of insulin receptor mRNA levels in rats with STZ-induced diabetes mellitus. Diabetes 41:1113-1118
-
(1992)
Diabetes
, vol.41
, pp. 1113-1118
-
-
Sechi, L.A.1
Griffin, C.A.2
Grady, E.F.3
Grunfeld, C.4
Kalinyak, J.E.5
Schambelan, M.6
-
77
-
-
0024451819
-
Mitochondrial and peroxisomal betaoxidation of stearic and lignoceric acids by rat brain
-
Singh H, Usher S, Poulos A (1989) Mitochondrial and peroxisomal betaoxidation of stearic and lignoceric acids by rat brain. J Neurochem 53:1711-1718
-
(1989)
J. Neurochem.
, vol.53
, pp. 1711-1718
-
-
Singh, H.1
Usher, S.2
Poulos, A.3
-
78
-
-
0029608958
-
A population-based study of tau-protein and ubiquitin in cerebrospinal fluid in 85-year-olds: Relation to severity of dementia and cerebral atrophy, but not to the apolipoprotein E4 allele
-
Skoog I, Vanmechelen E, Andreasson LA, Palmertz B, Davidson P, Hesse C, Blennow K (1995) A population-based study of tau-protein and ubiquitin in cerebrospinal fluid in 85-year-olds: relation to severity of dementia and cerebral atrophy, but not to the apolipoprotein E4 allele. Neurodegeneration 4:433-442
-
(1995)
Neurodegeneration
, vol.4
, pp. 433-442
-
-
Skoog, I.1
Vanmechelen, E.2
Andreasson, L.A.3
Palmertz, B.4
Davidson, P.5
Hesse, C.6
Blennow, K.7
-
79
-
-
33845707784
-
PETof brain amyloid and tau in mild cognitive impairment
-
Small GW, Kepe V, Ercoli LM, Siddarth P, Bookheimer SY, Miller KJ, Lavretsky H, Burggren AC, Cole GM, Vinters HV, Thompson PM, Huang SC, Satyamurthy N, Phelps ME, Barrio JR (2006) PETof brain amyloid and tau in mild cognitive impairment. N Engl J Med 355:2652-2663
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 2652-2663
-
-
Small, G.W.1
Kepe, V.2
Ercoli, L.M.3
Siddarth, P.4
Bookheimer, S.Y.5
Miller, K.J.6
Lavretsky, H.7
Burggren, A.C.8
Cole, G.M.9
Vinters, H.V.10
Thompson, P.M.11
Huang, S.C.12
Satyamurthy, N.13
Phelps, M.E.14
Barrio, J.R.15
-
80
-
-
77957369183
-
Decreased pyurvate dehydrogenase complex activity in Huntington and Alzheimer brain
-
Sorbi S, Bird ED, Blass JP (1983) Decreased pyurvate dehydrogenase complex activity in Huntington and Alzheimer brain. Ann Neurol 21:509-510
-
(1983)
Ann. Neurol.
, vol.21
, pp. 509-510
-
-
Sorbi, S.1
Bird, E.D.2
Blass, J.P.3
-
81
-
-
0037128935
-
Tau blocks traffic organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
-
Stamer K, Vogel R, Thies E, Mandelkow E, Mandelkow EM (2002) Tau blocks traffic organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J Cell Biol 156:1051-1063
-
(2002)
J. Cell. Biol.
, vol.156
, pp. 1051-1063
-
-
Stamer, K.1
Vogel, R.2
Thies, E.3
Mandelkow, E.4
Mandelkow, E.M.5
-
82
-
-
15244351255
-
Impaired insulin and insulin-like growth factor expression and signalling mechanisms in Alzheimer's disease - Is this type 3 diabetes?
-
Steen E, Terry BM, Rivera EJ, Cannon JL, Neely TR, Tavares R, Xu XJ, Wands JR, de la Monte SM (2005) Impaired insulin and insulin-like growth factor expression and signalling mechanisms in Alzheimer's disease - is this type 3 diabetes? J Alzheimers Dis 7:63-80
-
(2005)
J. Alzheimers Dis.
, vol.7
, pp. 63-80
-
-
Steen, E.1
Terry, B.M.2
Rivera, E.J.3
Cannon, J.L.4
Neely, T.R.5
Tavares, R.6
Xu, X.J.7
Wands, J.R.8
De La Monte, S.M.9
-
83
-
-
0035691617
-
The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas
-
Szkudelski T (2001) The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Rev 50:536-546
-
(2001)
Physiol. Rev.
, vol.50
, pp. 536-546
-
-
Szkudelski, T.1
-
85
-
-
0028882328
-
Brain enzyme activities after intracerebroventricular injection of streptozotocin in rats receiving acetyl-L-carnitine
-
Terwel D, Prickaerts J, Mery F, Jolles J (1995) Brain enzyme activities after intracerebroventricular injection of streptozotocin in rats receiving acetyl-L-carnitine. Eur J Pharmacol 287:65-71
-
(1995)
Eur. J. Pharmacol.
, vol.287
, pp. 65-71
-
-
Terwel, D.1
Prickaerts, J.2
Mery, F.3
Jolles, J.4
-
86
-
-
0024345665
-
Distribution of insulin receptor-like immunoreactivity in the rat forebrain
-
Unger J, McNeill TH, Moxley RT, White M, Moss A, Livingston JN (1989) Distribution of insulin receptor-like immunoreactivity in the rat forebrain. Neuroscience 31:143-157
-
(1989)
Neuroscience
, vol.31
, pp. 143-157
-
-
Unger, J.1
McNeill, T.H.2
Moxley, R.T.3
White, M.4
Moss, A.5
Livingston, J.N.6
-
87
-
-
0019981647
-
Streptozotocin: A review on its pharmacology, efficacy, and toxicity
-
Weiss RB (1982) Streptozotocin: A review on its pharmacology, efficacy, and toxicity. Cancer Treat Rep 66:427-438
-
(1982)
Cancer Treat Rep.
, vol.66
, pp. 427-438
-
-
Weiss, R.B.1
-
88
-
-
0023271871
-
Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry
-
Werther GA, Hogg A, Oldfield BJ, McKinley MJ, Figdor R, Allen AM, Mendelsohn FA (1987) Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry. Endocrinology 121:1562-1570
-
(1987)
Endocrinology
, vol.121
, pp. 1562-1570
-
-
Werther, G.A.1
Hogg, A.2
Oldfield, B.J.3
McKinley, M.J.4
Figdor, R.5
Allen, A.M.6
Mendelsohn, F.A.7
-
89
-
-
0014314635
-
Bicarbonate and chloride shifts in rat brain during acute and prolonged respiratory acid-base changes
-
Weyne J, Demester G, Leusen I (1968a) Bicarbonate and chloride shifts in rat brain during acute and prolonged respiratory acid-base changes. Arch Int Physiol 76:415-433
-
(1968)
Arch. Int. Physiol.
, vol.76
, pp. 415-433
-
-
Weyne, J.1
Demester, G.2
Leusen, I.3
-
90
-
-
0014246942
-
Brain and blood lactate during acute and prologned respiratory acidosis and alkalosis
-
Weyne J, Demester G, Leusen I (1968b) Brain and blood lactate during acute and prologned respiratory acidosis and alkalosis. Arch Int Physiol 76:157-159
-
(1968)
Arch. Int. Physiol.
, vol.76
, pp. 157-159
-
-
Weyne, J.1
Demester, G.2
Leusen, I.3
-
91
-
-
0020544901
-
Glucose and amino acid metabolism in rat brain during sustained hypoglycaemia
-
Wong KL, Tyce GM (1983) Glucose and amino acid metabolism in rat brain during sustained hypoglycaemia. Neurochem Res 8:401-415
-
(1983)
Neurochem. Res.
, vol.8
, pp. 401-415
-
-
Wong, K.L.1
Tyce, G.M.2
-
92
-
-
0014801176
-
The influence of an increased intracranial pressure on the lactate, pyruvate, bicarbonate, phosphocreatine, ATP, ADP and AMP concentrations of the cerebral cortex of dogs
-
Zwetnow NN (1970) The influence of an increased intracranial pressure on the lactate, pyruvate, bicarbonate, phosphocreatine, ATP, ADP and AMP concentrations of the cerebral cortex of dogs. Acta Physiol Scand 79:158-166
-
(1970)
Acta Physiol. Scand.
, vol.79
, pp. 158-166
-
-
Zwetnow, N.N.1
|