Xanthoceraside attenuates learning and memory deficits via improving insulin signaling in STZ-induced AD rats

Neuroscience Letters

Volumn 543, Issue , 2013, Pages 115-120

  Liu, Peng ^a   Zou, Libo ^a   Jiao, Qing ^a   Chi, Tianyan ^a   Ji, Xuefei ^a   Qi, Yue ^a   Xu, Qian ^a   Wang, Lihua ^b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b INSTITUTE OF APPLIED ECOLOGY   (China)

Author keywords

Alzheimer's disease; CREB; Insulin signaling; Learning and memory; Xanthoceraside

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DONEPEZIL; HERBACEOUS AGENT; INSULIN; INSULIN RECEPTOR; MEMANTINE; MITOGEN ACTIVATED PROTEIN KINASE; NOOTROPIC AGENT; RAF PROTEIN; SAPONIN DERIVATIVE; SOMATOMEDIN C RECEPTOR; STREPTOZOCIN; UNCLASSIFIED DRUG; XANTHOCERASIDE;

ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MECHANISM; FEMALE; HIPPOCAMPUS; INSULIN SIGNALING; LEARNING DISORDER; MALE; MAZE TEST; MEMORY DISORDER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ALZHEIMER DISEASE; ANIMALS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HIPPOCAMPUS; INJECTIONS, INTRAVENTRICULAR; INSULIN; LEARNING DISORDERS; MALE; MAZE LEARNING; MEMORY DISORDERS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-RAF; RATS; RATS, WISTAR; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; SAPONINS; SIGNAL TRANSDUCTION; STREPTOZOCIN; TRITERPENES;

EID: 84877138257     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.02.065     Document Type: Article

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