-
1
-
-
0344517353
-
Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration
-
Alvarez G., Munoz-Montano J.R., Satrustegui J., Avila J., Bogonez E., and Diaz-Nido J. Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration. FEBS Lett. 453 (1999) 260-264
-
(1999)
FEBS Lett.
, vol.453
, pp. 260-264
-
-
Alvarez, G.1
Munoz-Montano, J.R.2
Satrustegui, J.3
Avila, J.4
Bogonez, E.5
Diaz-Nido, J.6
-
2
-
-
33644502516
-
NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation
-
Amadoro G., Ciotti M.T., Costanzi M., Cestari V., Calissano P., and Canu N. NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 2892-2897
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 2892-2897
-
-
Amadoro, G.1
Ciotti, M.T.2
Costanzi, M.3
Cestari, V.4
Calissano, P.5
Canu, N.6
-
3
-
-
0027757042
-
Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5
-
Baumann K., Mandelkow E.M., Biernat J., Piwnica-Worms H., and Mandelkow E. Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5. FEBS Lett. 336 (1993) 417-424
-
(1993)
FEBS Lett.
, vol.336
, pp. 417-424
-
-
Baumann, K.1
Mandelkow, E.M.2
Biernat, J.3
Piwnica-Worms, H.4
Mandelkow, E.5
-
5
-
-
44849144122
-
I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A
-
Chen S., Li B., Grundke-Iqbal I., and Iqbal K. I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A. J. Biol. Chem. 283 (2008) 10513-10521
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 10513-10521
-
-
Chen, S.1
Li, B.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
6
-
-
34248222543
-
Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression
-
Dickey C.A., Ash P., Klosak N., Lee W.C., Petrucelli L., Hutton M., and Eckman C.B. Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression. Mol. Neurodegener. 1 (2006) 6
-
(2006)
Mol. Neurodegener.
, vol.1
, pp. 6
-
-
Dickey, C.A.1
Ash, P.2
Klosak, N.3
Lee, W.C.4
Petrucelli, L.5
Hutton, M.6
Eckman, C.B.7
-
7
-
-
0019026208
-
Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase
-
Embi N., Rylatt D.B., and Cohen P. Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur. J. Biochem. 107 (1980) 519-527
-
(1980)
Eur. J. Biochem.
, vol.107
, pp. 519-527
-
-
Embi, N.1
Rylatt, D.B.2
Cohen, P.3
-
8
-
-
0034329543
-
Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants
-
Flaherty D.B., Soria J.P., Tomasiewicz H.G., and Wood J.G. Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants. J. Neurosci. Res. 62 (2000) 463-472
-
(2000)
J. Neurosci. Res.
, vol.62
, pp. 463-472
-
-
Flaherty, D.B.1
Soria, J.P.2
Tomasiewicz, H.G.3
Wood, J.G.4
-
9
-
-
0024745894
-
Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease
-
Goedert M., Spillantini M.G., Jakes R., Rutherford D., and Crowther R.A. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3 (1989) 519-526
-
(1989)
Neuron
, vol.3
, pp. 519-526
-
-
Goedert, M.1
Spillantini, M.G.2
Jakes, R.3
Rutherford, D.4
Crowther, R.A.5
-
10
-
-
0027214404
-
Phosphoprotein phosphatase activities in Alzheimer disease brain
-
Gong C.X., Singh T.J., Grundke-Iqbal I., and Iqbal K. Phosphoprotein phosphatase activities in Alzheimer disease brain. J. Neurochem. 61 (1993) 921-927
-
(1993)
J. Neurochem.
, vol.61
, pp. 921-927
-
-
Gong, C.X.1
Singh, T.J.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
11
-
-
0034859101
-
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
-
Grimes C.A., and Jope R.S. The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog. Neurobiol. 65 (2001) 391-426
-
(2001)
Prog. Neurobiol.
, vol.65
, pp. 391-426
-
-
Grimes, C.A.1
Jope, R.S.2
-
12
-
-
39849110726
-
The GSK3 hypothesis of Alzheimer's disease
-
Hooper C., Killick R., and Lovestone S. The GSK3 hypothesis of Alzheimer's disease. J. Neurochem. 104 (2008) 1433-1439
-
(2008)
J. Neurochem.
, vol.104
, pp. 1433-1439
-
-
Hooper, C.1
Killick, R.2
Lovestone, S.3
-
13
-
-
0033969771
-
Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice
-
Ikegami S., Harada A., and Hirokawa N. Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice. Neurosci. Lett. 279 (2000) 129-132
-
(2000)
Neurosci. Lett.
, vol.279
, pp. 129-132
-
-
Ikegami, S.1
Harada, A.2
Hirokawa, N.3
-
14
-
-
0036170771
-
Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta
-
Ivaska J., Nissinen L., Immonen N., Eriksson J.E., Kahari V.M., and Heino J. Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta. Mol. Cell. Biol. 22 (2002) 1352-1359
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1352-1359
-
-
Ivaska, J.1
Nissinen, L.2
Immonen, N.3
Eriksson, J.E.4
Kahari, V.M.5
Heino, J.6
-
15
-
-
0032947795
-
Anti-bipolar therapy: mechanism of action of lithium
-
Jope R.S. Anti-bipolar therapy: mechanism of action of lithium. Mol. Psychiatry 4 (1999) 117-128
-
(1999)
Mol. Psychiatry
, vol.4
, pp. 117-128
-
-
Jope, R.S.1
-
16
-
-
0035851175
-
Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice
-
Kins S., Crameri A., Evans D.R., Hemmings B.A., Nitsch R.M., and Gotz J. Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice. J. Biol. Chem. 276 (2001) 38193-38200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38193-38200
-
-
Kins, S.1
Crameri, A.2
Evans, D.R.3
Hemmings, B.A.4
Nitsch, R.M.5
Gotz, J.6
-
17
-
-
0029776032
-
A molecular mechanism for the effect of lithium on development
-
Klein P.S., and Melton D.A. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 8455-8459
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 8455-8459
-
-
Klein, P.S.1
Melton, D.A.2
-
18
-
-
0036103182
-
Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection
-
Li X., Bijur G.N., and Jope R.S. Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection. Bipolar Disord. 4 (2002) 137-144
-
(2002)
Bipolar Disord.
, vol.4
, pp. 137-144
-
-
Li, X.1
Bijur, G.N.2
Jope, R.S.3
-
19
-
-
47849120642
-
decrease of protein phosphatase 2a and its association with accumulation and hyperphosphorylation of tau in down syndrome
-
Liang Z., Liu F., Iqbal K., Grundke-Iqbal I., Wegiel J., and Gong C.X. decrease of protein phosphatase 2a and its association with accumulation and hyperphosphorylation of tau in down syndrome. J. Alzheimer's Dis. 13 (2008) 295-302
-
(2008)
J. Alzheimer's Dis.
, vol.13
, pp. 295-302
-
-
Liang, Z.1
Liu, F.2
Iqbal, K.3
Grundke-Iqbal, I.4
Wegiel, J.5
Gong, C.X.6
-
20
-
-
34548568958
-
GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis
-
Lin C.F., Chen C.L., Chiang C.W., Jan M.S., Huang W.C., and Lin Y.S. GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis. J. Cell. Sci. 120 (2007) 2935-2943
-
(2007)
J. Cell. Sci.
, vol.120
, pp. 2935-2943
-
-
Lin, C.F.1
Chen, C.L.2
Chiang, C.W.3
Jan, M.S.4
Huang, W.C.5
Lin, Y.S.6
-
21
-
-
27644478606
-
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
-
Liu F., Grundke-Iqbal I., Iqbal K., and Gong C.X. Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. Eur. J. Neurosci. 22 (2005) 1942-1950
-
(2005)
Eur. J. Neurosci.
, vol.22
, pp. 1942-1950
-
-
Liu, F.1
Grundke-Iqbal, I.2
Iqbal, K.3
Gong, C.X.4
-
22
-
-
47049089041
-
Activation of glycogen synthase kinase-3 inhibits protein phosphatase-2A and the underlying mechanisms
-
Liu G.P., Zhang Y., Yao X.Q., Zhang C.E., Fang J., Wang Q., and Wang J.Z. Activation of glycogen synthase kinase-3 inhibits protein phosphatase-2A and the underlying mechanisms. Neurobiol. Aging 29 9 (2007) 1348-1358
-
(2007)
Neurobiol. Aging
, vol.29
, Issue.9
, pp. 1348-1358
-
-
Liu, G.P.1
Zhang, Y.2
Yao, X.Q.3
Zhang, C.E.4
Fang, J.5
Wang, Q.6
Wang, J.Z.7
-
23
-
-
24144440042
-
Acute anoxia induces tau dephosphorylation in rat brain slices and its possible underlying mechanisms
-
Liu R., Pei J.J., Wang X.C., Zhou X.W., Tian Q., Winblad B., and Wang J.Z. Acute anoxia induces tau dephosphorylation in rat brain slices and its possible underlying mechanisms. J. Neurochem. 94 (2005) 1225-1234
-
(2005)
J. Neurochem.
, vol.94
, pp. 1225-1234
-
-
Liu, R.1
Pei, J.J.2
Wang, X.C.3
Zhou, X.W.4
Tian, Q.5
Winblad, B.6
Wang, J.Z.7
-
24
-
-
41149086325
-
Phosphorylated PP2A (tyrosine 307) is associated with Alzheimer neurofibrillary pathology
-
Liu R., Zhou X.W., Tanila H., Bjorkdahl C., Wang J.Z., Guan Z.Z., Cao Y., Gustafsson J.A., Winblad B., and Pei J.J. Phosphorylated PP2A (tyrosine 307) is associated with Alzheimer neurofibrillary pathology. J. Cell. Mol. Med. 12 (2008) 241-257
-
(2008)
J. Cell. Mol. Med.
, vol.12
, pp. 241-257
-
-
Liu, R.1
Zhou, X.W.2
Tanila, H.3
Bjorkdahl, C.4
Wang, J.Z.5
Guan, Z.Z.6
Cao, Y.7
Gustafsson, J.A.8
Winblad, B.9
Pei, J.J.10
-
25
-
-
34247865533
-
A chaperone-dependent GSK3beta transitional intermediate mediates activation-loop autophosphorylation
-
Lochhead P.A., Kinstrie R., Sibbet G., Rawjee T., Morrice N., and Cleghon V. A chaperone-dependent GSK3beta transitional intermediate mediates activation-loop autophosphorylation. Mol. Cell 24 (2006) 627-633
-
(2006)
Mol. Cell
, vol.24
, pp. 627-633
-
-
Lochhead, P.A.1
Kinstrie, R.2
Sibbet, G.3
Rawjee, T.4
Morrice, N.5
Cleghon, V.6
-
26
-
-
33244456786
-
Increased levels of granular tau oligomers: an early sign of brain aging and Alzheimer's disease
-
Maeda S., Sahara N., Saito Y., Murayama S., Ikai A., and Takashima A. Increased levels of granular tau oligomers: an early sign of brain aging and Alzheimer's disease. Neurosci. Res. 54 (2006) 197-201
-
(2006)
Neurosci. Res.
, vol.54
, pp. 197-201
-
-
Maeda, S.1
Sahara, N.2
Saito, Y.3
Murayama, S.4
Ikai, A.5
Takashima, A.6
-
27
-
-
0031037714
-
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5
-
Meijer L., Borgne A., Mulner O., Chong J.P., Blow J.J., Inagaki N., Inagaki M., Delcros J.G., and Moulinoux J.P. Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. Eur. J. Biochem. 243 (1997) 527-536
-
(1997)
Eur. J. Biochem.
, vol.243
, pp. 527-536
-
-
Meijer, L.1
Borgne, A.2
Mulner, O.3
Chong, J.P.4
Blow, J.J.5
Inagaki, N.6
Inagaki, M.7
Delcros, J.G.8
Moulinoux, J.P.9
-
28
-
-
0346875916
-
GSK-3-selective inhibitors derived from Tyrian purple indirubins
-
Meijer L., Skaltsounis A.L., Magiatis P., Polychronopoulos P., Knockaert M., Leost M., Ryan X.P., Vonica C.A., Brivanlou A., Dajani R., Crovace C., Tarricone C., Musacchio A., Roe S.M., Pearl L., and Greengard P. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem. Biol. 10 (2003) 1255-1266
-
(2003)
Chem. Biol.
, vol.10
, pp. 1255-1266
-
-
Meijer, L.1
Skaltsounis, A.L.2
Magiatis, P.3
Polychronopoulos, P.4
Knockaert, M.5
Leost, M.6
Ryan, X.P.7
Vonica, C.A.8
Brivanlou, A.9
Dajani, R.10
Crovace, C.11
Tarricone, C.12
Musacchio, A.13
Roe, S.M.14
Pearl, L.15
Greengard, P.16
-
29
-
-
38049170722
-
Coupling of mammalian target of rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of Tau
-
Meske V., Albert F., and Ohm T.G. Coupling of mammalian target of rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of Tau. J. Biol. Chem. 283 (2008) 100-109
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 100-109
-
-
Meske, V.1
Albert, F.2
Ohm, T.G.3
-
30
-
-
28844481487
-
Chronic lithium treatment decreases tau lesions by promoting ubiquitination in a mouse model of tauopathies
-
Nakashima H., Ishihara T., Suguimoto P., Yokota O., Oshima E., Kugo A., Terada S., Hamamura T., Trojanowski J.Q., Lee V.M., and Kuroda S. Chronic lithium treatment decreases tau lesions by promoting ubiquitination in a mouse model of tauopathies. Acta Neuropathol. 110 (2005) 547-556
-
(2005)
Acta Neuropathol.
, vol.110
, pp. 547-556
-
-
Nakashima, H.1
Ishihara, T.2
Suguimoto, P.3
Yokota, O.4
Oshima, E.5
Kugo, A.6
Terada, S.7
Hamamura, T.8
Trojanowski, J.Q.9
Lee, V.M.10
Kuroda, S.11
-
31
-
-
21044449225
-
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
-
Noble W., Planel E., Zehr C., Olm V., Meyerson J., Suleman F., Gaynor K., Wang L., LaFrancois J., Feinstein B., Burns M., Krishnamurthy P., Wen Y., Bhat R., Lewis J., Dickson D., and Duff K. Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 6990-6995
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 6990-6995
-
-
Noble, W.1
Planel, E.2
Zehr, C.3
Olm, V.4
Meyerson, J.5
Suleman, F.6
Gaynor, K.7
Wang, L.8
LaFrancois, J.9
Feinstein, B.10
Burns, M.11
Krishnamurthy, P.12
Wen, Y.13
Bhat, R.14
Lewis, J.15
Dickson, D.16
Duff, K.17
-
32
-
-
0032577899
-
WNT-1 and HGF regulate GSK3 beta activity and beta-catenin signaling in mammary epithelial cells
-
Papkoff J., and Aikawa M. WNT-1 and HGF regulate GSK3 beta activity and beta-catenin signaling in mammary epithelial cells. Biochem. Biophys. Res. Commun. 247 (1998) 851-858
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.247
, pp. 851-858
-
-
Papkoff, J.1
Aikawa, M.2
-
33
-
-
0035823496
-
Inhibition of protein phosphatase 2A overrides tau protein kinase I/glycogen synthase kinase 3 beta and cyclin-dependent kinase 5 inhibition and results in tau hyperphosphorylation in the hippocampus of starved mouse
-
Planel E., Yasutake K., Fujita S.C., and Ishiguro K. Inhibition of protein phosphatase 2A overrides tau protein kinase I/glycogen synthase kinase 3 beta and cyclin-dependent kinase 5 inhibition and results in tau hyperphosphorylation in the hippocampus of starved mouse. J. Biol. Chem. 276 (2001) 34298-34306
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34298-34306
-
-
Planel, E.1
Yasutake, K.2
Fujita, S.C.3
Ishiguro, K.4
-
34
-
-
11144227267
-
Linking alterations in tau phosphorylation and cleavage during neuronal apoptosis
-
Rametti A., Esclaire F., Yardin C., and Terro F. Linking alterations in tau phosphorylation and cleavage during neuronal apoptosis. J. Biol. Chem. 279 (2004) 54518-54528
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 54518-54528
-
-
Rametti, A.1
Esclaire, F.2
Yardin, C.3
Terro, F.4
-
35
-
-
40849095832
-
Lithium down-regulates tau in cultured cortical neurons: a possible mechanism of neuroprotection
-
Rametti A., Esclaire F., Yardin C., Cogne N., and Terro F. Lithium down-regulates tau in cultured cortical neurons: a possible mechanism of neuroprotection. Neurosci. Lett. 434 (2008) 93-98
-
(2008)
Neurosci. Lett.
, vol.434
, pp. 93-98
-
-
Rametti, A.1
Esclaire, F.2
Yardin, C.3
Cogne, N.4
Terro, F.5
-
36
-
-
0037197836
-
Tau is essential to beta -amyloid-induced neurotoxicity
-
Rapoport M., Dawson H.N., Binder L.I., Vitek M.P., and Ferreira A. Tau is essential to beta -amyloid-induced neurotoxicity. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 6364-6369
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 6364-6369
-
-
Rapoport, M.1
Dawson, H.N.2
Binder, L.I.3
Vitek, M.P.4
Ferreira, A.5
-
37
-
-
34248181511
-
Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model
-
Roberson E.D., Scearce-Levie K., Palop J.J., Yan F., Cheng I.H., Wu T., Gerstein H., Yu G.Q., and Mucke L. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science 316 (2007) 750-754
-
(2007)
Science
, vol.316
, pp. 750-754
-
-
Roberson, E.D.1
Scearce-Levie, K.2
Palop, J.J.3
Yan, F.4
Cheng, I.H.5
Wu, T.6
Gerstein, H.7
Yu, G.Q.8
Mucke, L.9
-
38
-
-
22344438508
-
Tau suppression in a neurodegenerative mouse model improves memory function
-
Santacruz K., Lewis J., Spires T., Paulson J., Kotilinek L., Ingelsson M., Guimaraes A., DeTure M., Ramsden M., McGowan E., Forster C., Yue M., Orne J., Janus C., Mariash A., Kuskowski M., Hyman B., Hutton M., and Ashe K.H. Tau suppression in a neurodegenerative mouse model improves memory function. Science 309 (2005) 476-481
-
(2005)
Science
, vol.309
, pp. 476-481
-
-
Santacruz, K.1
Lewis, J.2
Spires, T.3
Paulson, J.4
Kotilinek, L.5
Ingelsson, M.6
Guimaraes, A.7
DeTure, M.8
Ramsden, M.9
McGowan, E.10
Forster, C.11
Yue, M.12
Orne, J.13
Janus, C.14
Mariash, A.15
Kuskowski, M.16
Hyman, B.17
Hutton, M.18
Ashe, K.H.19
-
39
-
-
0033605639
-
Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A
-
Seeling J.M., Miller J.R., Gil R., Moon R.T., White R., and Virshup D.M. Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A. Science 283 (1999) 2089-2091
-
(1999)
Science
, vol.283
, pp. 2089-2091
-
-
Seeling, J.M.1
Miller, J.R.2
Gil, R.3
Moon, R.T.4
White, R.5
Virshup, D.M.6
-
40
-
-
0028978701
-
Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau
-
Seubert P., Mawal-Dewan M., Barbour R., Jakes R., Goedert M., Johnson G.V., Litersky J.M., Schenk D., Lieberburg I., Trojanowski J.Q., et al. Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau. J. Biol. Chem. 270 (1995) 18917-18922
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18917-18922
-
-
Seubert, P.1
Mawal-Dewan, M.2
Barbour, R.3
Jakes, R.4
Goedert, M.5
Johnson, G.V.6
Litersky, J.M.7
Schenk, D.8
Lieberburg, I.9
Trojanowski, J.Q.10
-
41
-
-
0027960448
-
Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation
-
Stambolic V., and Woodgett J.R. Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation. Biochem. J. 303 Pt 3 (1994) 701-704
-
(1994)
Biochem. J.
, vol.303
, Issue.PART 3
, pp. 701-704
-
-
Stambolic, V.1
Woodgett, J.R.2
-
42
-
-
44649141999
-
Lithium treatment decreases activities of tau kinases in a murine model of senescence
-
Tajes M., Gutierrez-Cuesta J., Folch J., Ferrer I., Caballero B., Smith M.A., Casadesus G., Camins A., and Pallas M. Lithium treatment decreases activities of tau kinases in a murine model of senescence. J. Neuropathol. Exp. Neurol. 67 (2008) 612-623
-
(2008)
J. Neuropathol. Exp. Neurol.
, vol.67
, pp. 612-623
-
-
Tajes, M.1
Gutierrez-Cuesta, J.2
Folch, J.3
Ferrer, I.4
Caballero, B.5
Smith, M.A.6
Casadesus, G.7
Camins, A.8
Pallas, M.9
-
43
-
-
19544362550
-
Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease
-
Tanimukai H., Grundke-Iqbal I., and Iqbal K. Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease. Am. J. Pathol. 166 (2005) 1761-1771
-
(2005)
Am. J. Pathol.
, vol.166
, pp. 1761-1771
-
-
Tanimukai, H.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
44
-
-
40449098952
-
Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice
-
Terwel D., Muyllaert D., Dewachter I., Borghgraef P., Croes S., Devijver H., and Van Leuven F. Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice. Am. J. Pathol. 172 (2008) 786-798
-
(2008)
Am. J. Pathol.
, vol.172
, pp. 786-798
-
-
Terwel, D.1
Muyllaert, D.2
Dewachter, I.3
Borghgraef, P.4
Croes, S.5
Devijver, H.6
Van Leuven, F.7
-
45
-
-
0037390480
-
Lithium, but not valproate, induces the serine/threonine phosphatase activity of protein phosphatase 2A in the rat brain, without affecting its expression
-
Tsuji S., Morinobu S., Tanaka K., Kawano K., and Yamawaki S. Lithium, but not valproate, induces the serine/threonine phosphatase activity of protein phosphatase 2A in the rat brain, without affecting its expression. J. Neural Transm. 110 (2003) 413-425
-
(2003)
J. Neural Transm.
, vol.110
, pp. 413-425
-
-
Tsuji, S.1
Morinobu, S.2
Tanaka, K.3
Kawano, K.4
Yamawaki, S.5
-
46
-
-
0035075793
-
PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus
-
Vogelsberg-Ragaglia V., Schuck T., Trojanowski J.Q., and Lee V.M. PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus. Exp. Neurol. 168 (2001) 402-412
-
(2001)
Exp. Neurol.
, vol.168
, pp. 402-412
-
-
Vogelsberg-Ragaglia, V.1
Schuck, T.2
Trojanowski, J.Q.3
Lee, V.M.4
-
47
-
-
34548190489
-
An aluminum-based rat model for Alzheimer's disease exhibits oxidative damage, inhibition of PP2A activity, hyperphosphorylated tau, and granulovacuolar degeneration
-
Walton J.R. An aluminum-based rat model for Alzheimer's disease exhibits oxidative damage, inhibition of PP2A activity, hyperphosphorylated tau, and granulovacuolar degeneration. J. Inorg. Biochem. 101 (2007) 1275-1284
-
(2007)
J. Inorg. Biochem.
, vol.101
, pp. 1275-1284
-
-
Walton, J.R.1
-
48
-
-
0028902487
-
Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B
-
Wang J.Z., Gong C.X., Zaidi T., Grundke-Iqbal I., and Iqbal K. Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B. J. Biol. Chem. 270 (1995) 4854-4860
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 4854-4860
-
-
Wang, J.Z.1
Gong, C.X.2
Zaidi, T.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
49
-
-
0028176021
-
Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation
-
Wang Q.M., Fiol C.J., DePaoli-Roach A.A., and Roach P.J. Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation. J. Biol. Chem. 269 (1994) 14566-14574
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 14566-14574
-
-
Wang, Q.M.1
Fiol, C.J.2
DePaoli-Roach, A.A.3
Roach, P.J.4
-
50
-
-
14944347390
-
Inactivation of GSK-3beta in okadaic acid-induced neurodegeneration: relevance to Alzheimer's disease
-
Yoon S.Y., Choi J.E., Huh J.W., Hwang O., Nam Hong H., and Kim D. Inactivation of GSK-3beta in okadaic acid-induced neurodegeneration: relevance to Alzheimer's disease. NeuroReport 16 (2005) 223-227
-
(2005)
NeuroReport
, vol.16
, pp. 223-227
-
-
Yoon, S.Y.1
Choi, J.E.2
Huh, J.W.3
Hwang, O.4
Nam Hong, H.5
Kim, D.6
-
51
-
-
36048962439
-
Inverse in silico screening for identification of kinase inhibitor targets
-
Zahler S., Tietze S., Totzke F., Kubbutat M., Meijer L., Vollmar A.M., and Apostolakis J. Inverse in silico screening for identification of kinase inhibitor targets. Chem. Biol. 14 (2007) 1207-1214
-
(2007)
Chem. Biol.
, vol.14
, pp. 1207-1214
-
-
Zahler, S.1
Tietze, S.2
Totzke, F.3
Kubbutat, M.4
Meijer, L.5
Vollmar, A.M.6
Apostolakis, J.7
|