Improvement of brain energy metabolism and cholinergic functions contributes to the beneficial effects of silibinin against streptozotocin induced memory impairment

Behavioural Brain Research

Volumn 221, Issue 1, 2011, Pages 207-215

  Tota, Santoshkumar ^a   Kamat, Pradeep Kumar ^a   Shukla, Rakesh ^a   Nath, Chandishwar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Acetylcholinesterase expression; Brain energy metabolism; Memory impairment; Oxidative stress; Silibinin; Streptozotocin

Indexed keywords

ACETYLCHOLINESTERASE; ADENOSINE TRIPHOSPHATE; BUNGAROTOXIN RECEPTOR; CALCIUM; GLUTATHIONE; MALONALDEHYDE; MESSENGER RNA; NITRITE; REACTIVE OXYGEN METABOLITE; SILIBININ; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN METABOLISM; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; DRUG DOSE COMPARISON; ENERGY METABOLISM; ENZYME ACTIVITY; MALE; MAZE TEST; MEMORY DISORDER; MOUSE; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPTOSOME; TREATMENT OUTCOME;

ACETYLCHOLINESTERASE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIOXIDANTS; BRAIN; CALCIUM; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; ENERGY METABOLISM; GLUTATHIONE; MALE; MALONDIALDEHYDE; MAZE LEARNING; MEMORY DISORDERS; MICE; MOTOR ACTIVITY; OXIDATIVE STRESS; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; RECEPTORS, NICOTINIC; SILYMARIN; STREPTOZOCIN; SYNAPTOSOMES;

EID: 79953252716     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.02.041     Document Type: Article

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