Extracellular nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism

Journal of Biological Chemistry

Volumn 283, Issue 50, 2008, Pages 34833-34843

  Li, Yankun ^a,f   Zhang, Yuan ^a,f   Dorweiler, Bernhard ^a,c   Cui, Dongying ^a   Wang, Tao ^d   Woo, Connie W ^a   Brunkan, Cynthia S ^e   Wolberger, Cynthia ^d   Imai, Shin Ichiro ^e   Tabas, Ira ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NewYork Presbyterian Hospital   (United States)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDES; CELL DEATH; CHEMICAL ACTIVATION; ELECTRIC LOAD MANAGEMENT; ELECTRIC RESISTANCE; ENZYME ACTIVITY; ENZYMES; NUTRITION;

ADIPOCYTES; APOPTOSIS; B CELLS; CELL SURVIVALS; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; ER STRESSES; EXTRACELLULAR; INDUCED APOPTOSIS; NICOTINAMIDE MONONUCLEOTIDE; NONENZYMATIC; PATHO PHYSIOLOGIES; PLASMA LEVELS; SEQUENTIAL PROCESSES; SIGNAL TRANSDUCERS; SIGNALING MECHANISMS; SIGNALING PATHWAYS;

MACROPHAGES;

CHOLESTEROL; INTERLEUKIN 6; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; STAT3 PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; MACROPHAGE; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACRYLAMIDES; ANIMALS; APOPTOSIS; CELL SURVIVAL; CYTOKINES; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; INTERLEUKIN-6; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; NICOTINAMIDE MONONUCLEOTIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PIPERIDINES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 58049200121     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805866200     Document Type: Article

References (61)

1. Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., and Ferrante, A. W., Jr. (2003) J. Clin. Invest. 112, 1796-1808
2. Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., and Chen, H. (2003) J. Clin. Invest. 112, 1821-1830
3. Wellen, K. E., and Hotamisligil, G. S. (2005) J. Clin. Invest. 115, 1111-1119
4. Wilson, P. W., D'Agostino, R. B., Parise, H., Sullivan, L., and Meigs, J. B. (2005) Circulation 112, 3066-3072
5. Irigaray, P., Newby, J. A., Lacomme, S., and Belpomme, D. (2007) Biomed. Pharmacother. 61, 665-678
6. Porta, C., Subhra, K. B., Larghi, P., Rubino, L., Mancino, A., and Sica, A. (2007) Adv. Exp. Med. Biol. 604, 67-86
7. Miselis, N. R., Wu, Z. J., Van, R. N., and Kane, A. B. (2008) Mol. Cancer Ther. 7, 788-799
8. Vandivier, R. W., Henson, P. M., and Douglas, I. S. (2006) Chest 129, 1673-1682
9. Liu, J., Thewke, D. P., Su, Y. R., Linton, M. F., Fazio, S., and Sinensky, M. S. (2005) Arterioscler. Thromb. Vasc. Biol. 25, 174-179
10. Arai, S., Shelton, J. M., Chen, M., Bradley, M. N., Castrillo, A., Bookout, A. L., Mak, P. A., Edwards, P. A., Mangelsdorf, D. J., Tontonoz, P., and Miyazaki, T. (2005) Cell Metab. 1, 201-213
11. Tabas, I. (2005) Arterioscler. Thromb. Vasc. Biol. 25, 2255-2264
12. Schrijvers, D. M., De Meyer, G. R., Herman, A. G., and Martinet, W. (2007) Cardiovasc. Res. 73, 470-480
13. Matarese, G., Mantzoros, C., and La, C. A. (2007) Curr. Pharm. Des. 13, 3676-3680
14. Tilg, H., and Moschen, A. R. (2008) Clin. Sci. (Lond.) 114, 275-288
15. Luk, T., Malam, Z., and Marshall, J. C. (2008) J. Leukocyte Biol. 83, 804-816
16. Revollo, J. R., Grimm, A. A., and Imai, S. (2004) J. Biol. Chem. 279, 50754-50763
17. Revollo, J. R., Grimm, A. A., and Imai, S. (2007) Curr. Opin. Gastroenterol. 23, 164-170
18. Samal, B., Sun, Y., Stearns, G., Xie, C., Suggs, S., and McNiece, I. (1994) Mol. Cell. Biol. 14, 1431-1437
19. Jia, S. H., Li, Y., Parodo, J., Kapus, A., Fan, L., Rotstein, O. D., and Marshall, J. C. (2004) J. Clin. Invest. 113, 1318-1327
20. Revollo, J. R., Korner, A., Mills, K. F., Satoh, A., Wang, T., Garten, A., Dasgupta, B., Sasaki, Y., Wolberger, C., Townsend, R. R., Milbrandt, J., Kiess, W., and Imai, S. (2007) Cell Metab. 6, 363-375
21. Berndt, J., Kloting, N., Kralisch, S., Kovacs, P., Fasshauer, M., Schon, M. R., Stumvoll, M., and Bluher, M. (2005) Diabetes 54, 2911-2916
22. Haider, D. G., Holzer, G., Schaller, G., Weghuber, D., Widhalm, K., Wagner, O., Kapiotis, S., and Wolzt, M. (2006) J. Pediatr. Gastroenterol. Nutr. 43, 548-549
23. Sandeep, S., Velmurugan, K., Deepa, R., and Mohan, V. (2007) Metabolism 56, 565-570
24. Chen, M. P., Chung, F. M., Chang, D. M., Tsai, J. C., Huang, H. F., Shin, S. J., and Lee, Y. J. (2006) J. Clin. Endocrinol. Metab. 91, 295-299
25. Moschen, A. R., Kaser, A., Enrich, B., Mosheimer, B., Theurl, M., Niederegger, H., and Tilg, H. (2007) J. Immunol. 178, 1748-1758
26. Busso, N., Karababa, M., Nobile, M., Rolaz, A., Van, G. F., Galli, M., Leo, O., So, A., and De, S. T. (2008) PLoS ONE 3, e2267
27. Fukuhara, A., Matsuda, M., Nishizawa, M., Segawa, K., Tanaka, M., Kishimoto, K., Matsuki, Y., Murakami, M., Ichisaka, T., Murakami, H., Watanabe, E., Takagi, T., Akiyoshi, M., Ohtsubo, T., Kihara, S., Yamashita, S., Makishima, M., Funahashi, T., Yamanaka, S., Hiramatsu, R., Matsuzawa, Y., and Shimomura, I. (2005) Science 307, 426-430
28. Fukuhara, A., Matsuda, M., Nishizawa, M., Segawa, K., Tanaka, M., Kishimoto, K., Matsuki, Y., Murakami, M., Ichisaka, T., Murakami, H., Watanabe, E., Takagi, T., Akiyoshi, M., Ohtsubo, T., Kihara, S., Yamashita, S., Makishima, M., Funahashi, T., Yamanaka, S., Hiramatsu, R., Matsuzawa, Y., and Shimomura, I. (2007) Science 318, 565
29. Ozcan, U., Cao, Q., Yilmaz, E., Lee, A. H., Iwakoshi, N. N., Ozdelen, E., Tuncman, G., Gorgun, C., Glimcher, L. H., and Hotamisligil, G. S. (2004) Science 306, 457-461
30. Boden, G., Duan, X., Homko, C., Molina, E. J., Song, W., Perez, O., Cheung, P., and Merali, S. (2008) Diabetes 57, 2438-2444
31. Feng, B., Yao, P. M., Li, Y., Devlin, C. M., Zhang, D., Harding, H. P., Sweeney, M., Rong, J. X., Kuriakose, G., Fisher, E. A., Marks, A. R., Ron, D., and Tabas, I. (2003) Nat. Cell Biol. 5, 781-792
32. DeVries-Seimon, T., Li, Y., Yao, P. M., Stone, E., Wang, Y., Davis, R. J., Flavell, R., and Tabas, I. (2005) J. Cell Biol. 171, 61-73
33. Zhou, J., Lhotak, S., Hilditch, B. A., and Austin, R. C. (2005) Circulation 111, 1814-1821
34. Gargalovic, P. S., Gharavi, N. M., Clark, M. J., Pagnon, J., Yang, W. P., He, A., Truong, A., Baruch-Oren, T., Berliner, J. A., Kirchgessner, T. G., and Lusis, A. J. (2006) Arterioscler. Thromb. Vasc. Biol. 26, 2490-2496
35. Myoishi, M., Hao, H., Minamino, T., Watanabe, K., Nishihira, K., Hatakeyama, K., Asada, Y., Okada, K., Ishibashi-Ueda, H., Gabbiani, G., Bochaton-Piallat, M. L., Mochizuki, N., and Kitakaze, M. (2007) Circulation 116, 1226-1233
36. Han, S., Liang, C. P., DeVries-Seimon, T., Ranalletta, M., Welch, C. L., Collins-Fletcher, K., Accili, D., Tabas, I., and Tall, A. R. (2006) Cell Metab. 3, 257-266
37. Lee, A. S., and Hendershot, L. M. (2006) Cancer Biol. Ther. 5, 721-722
38. Havel, R. J., Eder, H., and Bragdon, J. (1955) J. Clin. Invest. 34, 1345-1353
39. Basu, S. K., Goldstein, J. L., Anderson, R. G. W., and Brown, M. S. (1976) Proc. Natl. Acad. Sci. U. S. A 73, 3178-3182
40. Cook, A. D., Braine, E. L., and Hamilton, J. A. (2003) J. Immunol. 171, 4816-4823
41. Li, Y., Ge, M., Ciani, L., Kuriakose, G., Westover, E., Dura, M., Covey, D., Freed, J. H., Maxfield, F. R., Lytton, J., and Tabas, I. (2004) J. Biol. Chem. 279, 37030-37039
42. Seimon, T. A., Obstfeld, A., Moore, K. J., Golenbock, D. T., and Tabas, I. (2006) Proc. Natl. Acad. Sci. U. S. A 103, 19794-19799
43. Yao, P. M., and Tabas, I. (2000) J. Biol. Chem. 275, 23807-23813
44. Wang, T., Zhang, X., Bheda, P., Revollo, J. R., Imai, S., and Wolberger, C. (2006) Nat. Struct. Mol. Biol. 13, 661-662
45. Brown, A. J., and Jessup, W. (1999) Atherosclerosis 142, 1-28
46. Hirano, T., Ishihara, K., and Hibi, M. (2000) Oncogene 19, 2548-2556
47. Nielsen, M., Kaltoft, K., Nordahl, M., Ropke, C., Geisler, C., Mustelin, T., Dobson, P., Svejgaard, A., and Odum, N. (1997) Proc. Natl. Acad. Sci. U. S. A 94, 6764-6769
48. Lang, R. (2005) Immunobiology 210, 63-76
49. Tsutsumi, S., Gupta, S. K., Hogan, V., Tanaka, N., Nakamura, K. T., Nabi, I. R., and Raz, A. (2003) FEBS Lett. 534, 49-53
50. Nowell, M. A., Richards, P. J., Fielding, C. A., Ognjanovic, S., Topley, N., Williams, A. S., Bryant-Greenwood, G., and Jones, S. A. (2006) Arthritis Rheum. 54, 2084-2095
51. Marriott, H. M., Hellewell, P. G., Cross, S. S., Ince, P. G., Whyte, M. K., and Dockrell, D. H. (2006) J. Immunol. 177, 6480-6488
52. Deng, J., Lu, P. D., Zhang, Y., Scheuner, D., Kaufman, R. J., Sonenberg, N., Harding, H. P., and Ron, D. (2004) Mol. Cell. Biol. 24, 10161-10168
53. Endo, M., Mori, M., Akira, S., and Gotoh, T. (2006) J. Immunol. 176, 6245-6253
54. Knorre, A., Wagner, M., Schaefer, H. E., Colledge, W. H., and Pahl, H. L. (2002) Biol. Chem. 383, 271-282
55. Li, Y., Schwabe, R. F., DeVries-Seimon, T., Yao, P. M., Gerbod-Giannone, M. C., Tall, A. R., Davis, R. J., Flavell, R., Brenner, D. A., and Tabas, I. (2005) J. Biol. Chem. 280, 21763-21772
56. Naugler, W. E., and Karin, M. (2008) Trends Mol. Med. 14, 109-119
57. Libby, P., and Clinton, S. K. (1993) Curr. Opin. Lipidol. 4, 355-363
58. Hodge, D. R., Hurt, E. M., and Farrar, W. L. (2005) Eur. J. Cancer 41, 2502-2512
59. Zhu, P., Baek, S. H., Bourk, E. M., Ohgi, K. A., Garcia-Bassets, I., Sanjo, H., Akira, S., Kotol, P. F., Glass, C. K., Rosenfeld, M. G., and Rose, D. W. (2006) Cell 124, 615-629
60. Olesen, U. H., Christensen, M. K., Bjorkling, F., Jaattela, M., Jensen, P. B., Sehested, M., and Nielsen, S. J. (2008) Biochem. Biophys. Res. Commun. 367, 799-804
61. Dahl, T. B., Yndestad, A., Skjelland, M., Oie, E., Dahl, A., Michelsen, A., Damas, J. K., Tunheim, S. H., Ueland, T., Smith, C., Bendz, B., Tonstad, S., Gullestad, L., Froland, S. S., Krohg-Sorensen, K., Russell, D., Aukrust, P., and Halvorsen, B. (2007) Circulation 115, 972-980