Crystal structure of Rattus norvegicus Visfatin/PBEF/Nampt in complex with an FK866-based inhibitor

Molecules and Cells

Volumn 27, Issue 6, 2009, Pages 667-671

  Kang, Gil Bu ^a   Bae, Man Ho ^a   Kim, Mun Kyoung ^a   Im, Isak ^a   Kim, Yong Chul ^a   Eom, Soo Hyun ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

Crystal structure; FK866; Nicotinamide phosphoribosyltransferase (Nampt); Pre B cell colony enhancing factor (PBEF); Visfatin

Indexed keywords

FK 866; GLYCOSYLTRANSFERASE INHIBITOR; IS 001; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOSYNTHESIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT; SOLUBILITY; STRUCTURAL BIOINFORMATICS; STRUCTURE ACTIVITY RELATION; TUMOR CELL;

ACRYLAMIDES; ANIMALS; BINDING SITES; CALORIMETRY; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PIPERIDINES; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PYRIDINIUM COMPOUNDS; RATS;

RATTUS; RATTUS NORVEGICUS;

EID: 67650314923     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10059-009-0088-x     Document Type: Article

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