Age-associated weight gain, leptin, and SIRT1: A possible role for hypothalamic SIRT1 in the prevention of weight gain and aging through modulation of leptin sensitivity

Frontiers in Endocrinology

Volumn 6, Issue JUL, 2015, Pages

  Sasaki, Tsutomu ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Aging; Energy homeostasis; Energy sensing; Inflammation; Insulin resistance; Leptin resistance; Sirtuin; Ubiquitin proteasome system

Indexed keywords

AGOUTI RELATED PROTEIN; HISTONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEPTIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PROOPIOMELANOCORTIN; SIRTUIN 1; TRANSCRIPTION FACTOR;

AGING; ARCUATE NUCLEUS; BODY MASS; CALORIC INTAKE; DIET; ENERGY BALANCE; ENERGY EXPENDITURE; HOMEOSTASIS; HUMAN; HYPOTHALAMUS; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; NONHUMAN; OBESITY; PREVALENCE; REVIEW; SIGNAL TRANSDUCTION;

EID: 84938866188     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2015.00109     Document Type: Review

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