메뉴 건너뛰기




Volumn 63, Issue 12, 2014, Pages 4083-4088

Central insulin administration improves whole-body insulin sensitivity via hypothalamus and parasympathetic outputs in men

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; PLACEBO; ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL;

EID: 84911916822     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0477     Document Type: Article
Times cited : (138)

References (26)
  • 1
    • 45749158925 scopus 로고    scopus 로고
    • Central insulin action regulates peripheral glucose and fat metabolism in mice
    • Koch L, Wunderlich FT, Seibler J, et al. Central insulin action regulates peripheral glucose and fat metabolism in mice. J Clin Invest 2008;118:2132-2147
    • (2008) J Clin Invest , vol.118 , pp. 2132-2147
    • Koch, L.1    Wunderlich, F.T.2    Seibler, J.3
  • 2
    • 84896315769 scopus 로고    scopus 로고
    • Risk of postprandial insulin resistance: The liver/vagus rapport
    • Macedo MP, Lima IS, Gaspar JM, et al. Risk of postprandial insulin resistance: the liver/vagus rapport. Rev Endocr Metab Disord 2014;15:67-77
    • (2014) Rev Endocr Metab Disord , vol.15 , pp. 67-77
    • Macedo, M.P.1    Lima, I.S.2    Gaspar, J.M.3
  • 3
    • 84867033830 scopus 로고    scopus 로고
    • Insulin activates Erk1/2 signaling in the dorsal vagal complex to inhibit glucose production
    • Filippi BM, Yang CS, Tang C, Lam TKT. Insulin activates Erk1/2 signaling in the dorsal vagal complex to inhibit glucose production. Cell Metab 2012;16:500-510
    • (2012) Cell Metab , vol.16 , pp. 500-510
    • Filippi, B.M.1    Yang, C.S.2    Tang, C.3    Lam, T.K.T.4
  • 4
    • 0036267472 scopus 로고    scopus 로고
    • Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats
    • Obici S, Feng Z, Karkanias G, Baskin DG, Rossetti L. Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats. Nat Neurosci 2002;5:566-572
    • (2002) Nat Neurosci , vol.5 , pp. 566-572
    • Obici, S.1    Feng, Z.2    Karkanias, G.3    Baskin, D.G.4    Rossetti, L.5
  • 5
    • 78649466467 scopus 로고    scopus 로고
    • CNS leptin and insulin action in the control of energy homeostasis
    • Belgardt BF, Brüning JC. CNS leptin and insulin action in the control of energy homeostasis. Ann N Y Acad Sci 2010;1212:97-113
    • (2010) Ann N Y Acad Sci , vol.1212 , pp. 97-113
    • Belgardt, B.F.1    Brüning, J.C.2
  • 6
    • 0036913187 scopus 로고    scopus 로고
    • Hypothalamic insulin signaling is required for inhibition of glucose production
    • Obici S, Zhang BB, Karkanias G, Rossetti L. Hypothalamic insulin signaling is required for inhibition of glucose production. Nat Med 2002;8:1376-1382
    • (2002) Nat Med , vol.8 , pp. 1376-1382
    • Obici, S.1    Zhang, B.B.2    Karkanias, G.3    Rossetti, L.4
  • 8
    • 82255181871 scopus 로고    scopus 로고
    • Stimulatory effect of insulin on glucose uptake by muscle involves the central nervous system in insulin-sensitive mice
    • Coomans CP, Biermasz NR, Geerling JJ, et al. Stimulatory effect of insulin on glucose uptake by muscle involves the central nervous system in insulin-sensitive mice. Diabetes 2011;60:3132-3140
    • (2011) Diabetes , vol.60 , pp. 3132-3140
    • Coomans, C.P.1    Biermasz, N.R.2    Geerling, J.J.3
  • 9
    • 79551506567 scopus 로고    scopus 로고
    • Brain insulin controls adipose tissue lipolysis and lipogenesis
    • Scherer T, O'Hare J, Diggs-Andrews K, et al. Brain insulin controls adipose tissue lipolysis and lipogenesis. Cell Metab 2011;13:183-194
    • (2011) Cell Metab , vol.13 , pp. 183-194
    • Scherer, T.1    O'Hare, J.2    Diggs-Andrews, K.3
  • 10
    • 84893726788 scopus 로고    scopus 로고
    • Intranasal insulin suppresses systemic but not subcutaneous lipolysis in healthy humans
    • Iwen KA, Scherer T, Heni M, et al. Intranasal insulin suppresses systemic but not subcutaneous lipolysis in healthy humans. J Clin Endocrinol Metab 2014;99:E246-E251
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. E246-E251
    • Iwen, K.A.1    Scherer, T.2    Heni, M.3
  • 11
    • 84860435420 scopus 로고    scopus 로고
    • Evidence against a physiologic role for acute changes in CNS insulin action in the rapid regulation of hepatic glucose production
    • Ramnanan CJ, Edgerton DS, Cherrington AD. Evidence against a physiologic role for acute changes in CNS insulin action in the rapid regulation of hepatic glucose production. Cell Metab 2012;15:656-664
    • (2012) Cell Metab , vol.15 , pp. 656-664
    • Ramnanan, C.J.1    Edgerton, D.S.2    Cherrington, A.D.3
  • 12
    • 32444447035 scopus 로고    scopus 로고
    • Insulin's effect on the liver: "direct or indirect?" continues to be the question
    • Girard J. Insulin's effect on the liver: "direct or indirect?" continues to be the question. J Clin Invest 2006;116:302-304
    • (2006) J Clin Invest , vol.116 , pp. 302-304
    • Girard, J.1
  • 14
    • 84859540472 scopus 로고    scopus 로고
    • Is insulin action in the brain clinically relevant?
    • Filippi BM, Mighiu PI, Lam TKT. Is insulin action in the brain clinically relevant? Diabetes 2012;61:773-775
    • (2012) Diabetes , vol.61 , pp. 773-775
    • Filippi, B.M.1    Mighiu, P.I.2    Lam, T.K.T.3
  • 16
    • 84876283390 scopus 로고    scopus 로고
    • Intranasal insulin modulates intrinsic reward and prefrontal circuitry of the human brain in lean women
    • Kullmann S, Frank S, Heni M, et al. Intranasal insulin modulates intrinsic reward and prefrontal circuitry of the human brain in lean women. Neuroendocrinology 2013;97:176-182
    • (2013) Neuroendocrinology , vol.97 , pp. 176-182
    • Kullmann, S.1    Frank, S.2    Heni, M.3
  • 17
    • 33747058235 scopus 로고    scopus 로고
    • The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: A magnetoencephalographic study
    • Tschritter O, Preissl H, Hennige AM, et al. The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: a magnetoencephalographic study. Proc Natl Acad Sci U S A 2006;103:12103-12108
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 12103-12108
    • Tschritter, O.1    Preissl, H.2    Hennige, A.M.3
  • 18
    • 84859438415 scopus 로고    scopus 로고
    • The obese brain: Association of body mass index and insulin sensitivity with resting state network functional connectivity
    • Kullmann S, Heni M, Veit R, et al. The obese brain: association of body mass index and insulin sensitivity with resting state network functional connectivity. Hum Brain Mapp 2012;33:1052-1061
    • (2012) Hum Brain Mapp , vol.33 , pp. 1052-1061
    • Kullmann, S.1    Heni, M.2    Veit, R.3
  • 19
    • 78751485383 scopus 로고    scopus 로고
    • Intranasal insulin enhances postprandial thermogenesis and lowers postprandial serum insulin levels in healthy men
    • Benedict C, Brede S, Schiöth HB, et al. Intranasal insulin enhances postprandial thermogenesis and lowers postprandial serum insulin levels in healthy men. Diabetes 2011;60:114-118
    • (2011) Diabetes , vol.60 , pp. 114-118
    • Benedict, C.1    Brede, S.2    Schiöth, H.B.3
  • 20
    • 84865434170 scopus 로고    scopus 로고
    • Nasal insulin changes peripheral insulin sensitivity simultaneously with altered activity in homeostatic and reward-related human brain regions
    • Heni M, Kullmann S, Ketterer C, et al. Nasal insulin changes peripheral insulin sensitivity simultaneously with altered activity in homeostatic and reward-related human brain regions. Diabetologia 2012;55:1773-1782
    • (2012) Diabetologia , vol.55 , pp. 1773-1782
    • Heni, M.1    Kullmann, S.2    Ketterer, C.3
  • 21
    • 38349131004 scopus 로고    scopus 로고
    • Empirical optimization of ASL data analysis using an ASL data processing toolbox: ASLtbx
    • Wang Z, Aquirre GK, Rao H, et al. Empirical optimization of ASL data analysis using an ASL data processing toolbox: ASLtbx. Magn Reson Imaging 2008;26:261-269
    • (2008) Magn Reson Imaging , vol.26 , pp. 261-269
    • Wang, Z.1    Aquirre, G.K.2    Rao, H.3
  • 22
    • 84861564552 scopus 로고    scopus 로고
    • Fat intake modulates cerebral blood flow in homeostatic and gustatory brain areas in humans
    • Frank S, Linder K, Kullmann S, et al. Fat intake modulates cerebral blood flow in homeostatic and gustatory brain areas in humans. Am J Clin Nutr 2012;95:1342-1349
    • (2012) Am J Clin Nutr , vol.95 , pp. 1342-1349
    • Frank, S.1    Linder, K.2    Kullmann, S.3
  • 23
    • 0025297310 scopus 로고
    • Peripheral effects of insulin dominate suppression of fasting hepatic glucose production
    • Ader M, Bergman RN. Peripheral effects of insulin dominate suppression of fasting hepatic glucose production. Am J Physiol 1990;258:E1020-E1032
    • (1990) Am J Physiol , vol.258 , pp. E1020-E1032
    • Ader, M.1    Bergman, R.N.2
  • 25
    • 84893766301 scopus 로고    scopus 로고
    • Differential effect of glucose ingestion on the neural processing of food stimuli in lean and overweight adults
    • Heni M, Kullmann S, Ketterer C, et al. Differential effect of glucose ingestion on the neural processing of food stimuli in lean and overweight adults. Hum Brain Mapp 2014;35:918-928
    • (2014) Hum Brain Mapp , vol.35 , pp. 918-928
    • Heni, M.1    Kullmann, S.2    Ketterer, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.