Reciprocal modulation of toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids

Journal of Biological Chemistry

Volumn 278, Issue 39, 2003, Pages 37041-37051

  Lee, Joo Y ^a,b   Ye, Jianping ^c   Gao, Zhanguo ^a,b   Youn, Hyung S ^a,b   Lee, Won H ^a,b   Zhao, Ling ^a,b   Sizemore, Nywana ^d   Hwang, Daniel H ^a,b  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; FATTY ACIDS; GENES; MUTAGENESIS;

MOLECULAR TARGETS;

BIOCHEMISTRY;

2 MORPHOLINO 8 PHENYLCHROMONE; ADAPTOR PROTEIN; CYCLOOXYGENASE 2; DOCOSAHEXAENOIC ACID; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; LAURIC ACID; LIPOPOLYSACCHARIDE; MUTANT PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHATIDYLINOSITOL 3 KINASE; POLYUNSATURATED FATTY ACID; PROTEIN; PROTEIN KINASE B; PROTEIN MD 2; SATURATED FATTY ACID; SYNAPTOTAGMIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; CELL STRAIN 293T; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; CELL LINE; CYCLOOXYGENASE 2; DOCOSAHEXAENOIC ACIDS; FATTY ACIDS; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; ISOENZYMES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PHOSPHORYLATION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0141844653     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M305213200     Document Type: Article

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