The obesity susceptibility gene cpe links foxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake

Nature Medicine

Volumn 15, Issue 10, 2009, Pages 1195-1201

  Plum, Leona ^a,e   Lin, Hua V ^a   Dutia, Roxanne ^a   Tanaka, Jun ^a   Aizawa, Kumiko S ^a   Matsumoto, Michihiro ^a,b   Kim, Andrea J ^a   Cawley, Niamh X ^c   Paik, Ji Hye ^d   Loh, Y Peng ^c   Depinho, Ronald A ^d   Wardlaw, Sharon L ^a   Accili, Domenico ^a  

^a NewYork Presbyterian Hospital   (United States)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^c Eunice Kennedy Shriver National Institute   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e DR WILLMAR SCHWABE GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; BETA ENDORPHIN; CARBOXYPEPTIDASE H; PROOPIOMELANOCORTIN; TRANSCRIPTION FACTOR FKHR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENERGY EXPENDITURE; FEMALE; FOOD INTAKE; GENE DELETION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE MUTATION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HORMONAL REGULATION; HYPOTHALAMUS; MALE; MOUSE; NERVE CELL; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; WEIGHT GAIN; WEIGHT REDUCTION;

ALPHA-MSH; ANIMALS; ARCUATE NUCLEUS; BETA-ENDORPHIN; CARBOXYPEPTIDASE H; EATING; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HYPOTHALAMUS; MALE; MICE; MICE, KNOCKOUT; NEURONS; OBESITY; PRO-OPIOMELANOCORTIN; SIGNAL TRANSDUCTION;

MUS;

EID: 70350369729     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2026     Document Type: Article

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