Surfing the protein-protein interaction surface using docking methods: Application to the design of PPI inhibitors

Molecules

Volumn 20, Issue 6, 2015, Pages 11569-11603

  Sable, Rushikesh ^a   Jois, Seetharama ^a  

^a UNIVERSITY OF LOUISIANA AT MONROE   (United States)

Author keywords

Docking; Drug like molecules; Hot spots; Protein docking; Protein protein interactions; Virtual screening

Indexed keywords

LEAD; MOLECULAR LIBRARY; PROTEIN BINDING;

CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; HUMAN; MOLECULAR DOCKING; MOLECULAR LIBRARY; PHARMACOLOGY; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

DRUG DESIGN; HUMANS; LEAD; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPS; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84938243230     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules200611569     Document Type: Review

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