Protein-protein interactions: General trends in the relationship between binding affinity and interfacial buried surface area

Protein Science

Volumn 22, Issue 4, 2013, Pages 510-515

  Chen, Jieming ^a   Sawyer, Nicholas ^a   Regan, Lynne ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

Buried surface area; Dissociation constant; Hot spot; Hydrophobicity; Protein protein interaction; Surface energy density

Indexed keywords

HETERODIMER;

ARTICLE; BINDING AFFINITY; CHEMICAL COMPOSITION; DENSITY; DISSOCIATION CONSTANT; ENERGY; HISTONE MODIFICATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SURFACE PROPERTY; THERMODYNAMICS;

DATABASES, PROTEIN; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTEIN MULTIMERIZATION; PROTEIN SUBUNITS; PROTEINS; SURFACE PROPERTIES; THERMODYNAMICS;

EID: 84878306995     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.2230     Document Type: Article

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