Accounting for global protein deformability during protein-protein and protein-ligand docking

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1754, Issue 1-2, 2005, Pages 225-231

  May, Andreas ^a   Zacharias, Martin ^a  

^a JACOBS UNIVERSITY BREMEN   (Germany)

Author keywords

Approximate normal mode; Docking minimization; Domain motion; Induced fit binding; Ligand receptor interaction; Receptor flexibility

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; ESTERASE INHIBITOR; FK 506 BINDING PROTEIN; IMMUNOSUPPRESSIVE AGENT; LIGAND; PROTEIN KINASE INHIBITOR; RIBONUCLEASE A; STAUROSPORINE; TACROLIMUS;

BINDING KINETICS; BINDING SITE; CATALYSIS; CONFERENCE PAPER; LIGAND BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SCREENING; STRUCTURE ANALYSIS;

BINDING SITES; COMPUTER SIMULATION; CYCLIC AMP-DEPENDENT PROTEIN KINASES; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTEINS; STAUROSPORINE;

EID: 29144485503     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2005.07.045     Document Type: Conference Paper

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