Inhibitors of protein-protein interactions: New methodologies to tackle this challenge

Drug Discovery Today: Technologies

Volumn 10, Issue 4, 2013, Pages

  Silvian, Laura ^a   Enyedy, Istvan ^a   Kumaravel, Gnanasambandam ^a  

^a BIOGEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HORMONE RECEPTOR; HYDROXYPROLINE; MACROCYCLIC COMPOUND; PEPTIDOMIMETIC AGENT; SYNTHETIC DNA; TETRAPEPTIDE; UBIQUITIN PROTEIN LIGASE; WITHAFERIN A;

ANISOTROPY; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; BINDING AFFINITY; BINDING SITE; BIOINFORMATICS; CAPILLARY ELECTROPHORESIS; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; CRYSTALLIZATION; DRUG DESIGN; ELECTROSPRAY MASS SPECTROMETRY; HIGH THROUGHPUT SCREENING; HUMAN; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR MODEL; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; RIBOSOME; SPATIAL ORIENTATION; STOICHIOMETRY; SUPPORT VECTOR MACHINE; X RAY CRYSTALLOGRAPHY;

CRYSTALLIZATION; DRUG DESIGN; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEINS; SMALL MOLECULE LIBRARIES;

EID: 84886286398     PISSN: None     EISSN: 17406749     Source Type: Journal    
DOI: 10.1016/j.ddtec.2012.10.004     Document Type: Review

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