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Volumn 7, Issue 1, 1999, Pages 29-38

Two new β-strand mimics

Author keywords

Amino acids and derivs; Mimetics; Peptides and polypeptides; Solid phase synthesis

Indexed keywords

BENZOIC ACID DERIVATIVE; HYDRAZINE DERIVATIVE;

EID: 0032982070     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00225-9     Document Type: Article
Times cited : (29)

References (40)
  • 32
    • 0344125579 scopus 로고    scopus 로고
    • note
    • In an early attempt to synthesize artificial β-sheet 2, we used TFA instead of HCl and obtained a product in which the nitrile group hydrolyzed to the corresponding primary amide. As a result, the overall yield of 2 was only 11%. In other studies, we have also observed that the nitrile group is sensitive to hydrolysis by acids, and its sensitivity appears to be a general problem.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.