Computer-based de novo design of drug-like molecules

Nature Reviews Drug Discovery

Volumn 4, Issue 8, 2005, Pages 649-663

  Schneider, Gisbert ^a   Fechner, Uli ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOID 1 RECEPTOR; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR; LIGAND; PHOSPHOTRANSFERASE INHIBITOR; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; STEROL 14ALPHA DEMETHYLASE; THROMBIN INHIBITOR;

ALGORITHM; AUTOMATION; BINDING AFFINITY; COMPUTER AIDED DESIGN; COMPUTER MODEL; COMPUTER PROGRAM; COST EFFECTIVENESS ANALYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; LIGAND BINDING; MONTE CARLO METHOD; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; REVIEW;

COMPUTER-AIDED DESIGN; DRUG DESIGN; MODELS, MOLECULAR; TECHNOLOGY, PHARMACEUTICAL;

EID: 23844449940     PISSN: 14741776     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrd1799     Document Type: Review

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