Comparison of weak affinity chromatography and surface plasmon resonance in determining affinity of small molecules

Analytical Biochemistry

Volumn 461, Issue , 2014, Pages 57-59

  Duong Thi, Minh Dao ^a   Bergström, Gunnar ^b   Mandenius, Carl Fredrik ^b   Bergström, Maria ^a   Fex, Tomas ^c   Ohlson, Sten ^d  

^a LINNAEUS UNIVERSITY   (Sweden)

^b LINKÖPING UNIVERSITY   (Sweden)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Affinity determination; Fragment based drug discovery; Surface plasmon resonance; Thrombin; Weak affinity chromatography

Indexed keywords

AFFINITY CHROMATOGRAPHY; ENZYMES; ISOTHERMS; MOLECULES; PLASMONS; RESONANCE;

AFFINITY CONSTANTS; AFFINITY DETERMINATION; DRUG DISCOVERY; LANGMUIR ISOTHERM; PROTEIN INTERACTION; STEADY-STATE RESPONSE; STRONG CORRELATION; THROMBIN;

SURFACE PLASMON RESONANCE;

DIMETHYL SULFOXIDE; IMMOBILIZED PROTEIN; THROMBIN; MOLECULAR LIBRARY; PROTEIN BINDING;

AFFINITY CHROMATOGRAPHY; ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; SURFACE PLASMON RESONANCE; WEAK AFFINITY CHROMATOGRAPHY; HUMAN; KINETICS; METABOLISM; MOLECULAR LIBRARY; PROCEDURES;

CHROMATOGRAPHY, AFFINITY; HUMANS; KINETICS; PROTEIN BINDING; SMALL MOLECULE LIBRARIES; SURFACE PLASMON RESONANCE; THROMBIN;

EID: 84903973479     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2014.05.023     Document Type: Article

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