Molecular dissection of the CD2-CD58 counter-receptor interface identifies CD2 Tyr86 and CD58 Lys34 residues as the functional "hot spot"

Journal of Molecular Biology

Volumn 312, Issue 4, 2001, Pages 711-720

  Kim, Mikyung ^a,b   Sun, Zhen Yu J ^b   Byron, Olwyn ^c   Campbell, Gordon ^c   Wagner, Gerhard ^b   Wang, Jia huai ^a,b   Reinherz, Ellis L ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Adhesion complexes; Analytical ultracentrifugation; CD2 CD58; Isothermal titration calorimetry; Protein structure

Indexed keywords

CD2 ANTIGEN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; LYSINE; TYROSINE;

ARTICLE; BINDING AFFINITY; CALORIMETRY; CONCENTRATION RESPONSE; HYDROGEN BOND; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; ULTRACENTRIFUGATION;

EID: 0035965140     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4980     Document Type: Article

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