메뉴 건너뛰기




Volumn 66, Issue 2, 2015, Pages 222-247

Interferon Regulatory Factor Signalings in Cardiometabolic Diseases

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSOL RECEPTOR; INTERFERON; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 2; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 4; INTERFERON REGULATORY FACTOR 5; INTERFERON REGULATORY FACTOR 6; INTERFERON REGULATORY FACTOR 7; INTERFERON REGULATORY FACTOR 9; PATTERN RECOGNITION RECEPTOR;

EID: 84937574251     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.115.04898     Document Type: Review
Times cited : (45)

References (277)
  • 1
    • 79952827722 scopus 로고    scopus 로고
    • Environmental risk conditions and pathways to cardiometabolic diseases in indigenous populations
    • Daniel M, Lekkas P, Cargo M, Stankov I, Brown A., Environmental risk conditions and pathways to cardiometabolic diseases in indigenous populations. Annu Rev Public Health 2011;32:327-347. doi: 10.1146/annurev.publhealth.012809.103557
    • (2011) Annu Rev Public Health , vol.32 , pp. 327-347
    • Daniel, M.1    Lekkas, P.2    Cargo, M.3    Stankov, I.4    Brown, A.5
  • 2
    • 84922381210 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2015 update: A report from the American Heart Association
    • Mozaffarian D, Benjamin EJ, Go AS, American Heart Association Statistics Committee and Stroke Statistics Subcommittee Heart disease and stroke statistics-2015 update: A report from the American Heart Association. Circulation 2015;131:e29-322. doi: 10.1161/CIR.0000000000000152
    • (2015) Circulation , vol.131 , pp. e29-322
    • Mozaffarian, D.1    Benjamin, E.J.2    Go, A.S.3
  • 3
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS., Inflammation and metabolic disorders. Nature 2006;444:860-867. doi: 10.1038/nature05485
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 4
    • 33845914986 scopus 로고    scopus 로고
    • Mechanisms linking obesity with cardiovascular disease
    • Van Gaal LF, Mertens IL, De Block CE., Mechanisms linking obesity with cardiovascular disease. Nature 2006;444:875-880. doi: 10.1038/nature05487
    • (2006) Nature , vol.444 , pp. 875-880
    • Van Gaal, L.F.1    Mertens, I.L.2    De Block, C.E.3
  • 5
    • 84929607347 scopus 로고    scopus 로고
    • Reply to: "Interferon regulatory factor 9 plays a dual function in health and disease"
    • Zhang XJ, Wang PX, Zhang P, Li H., Reply to: "Interferon regulatory factor 9 plays a dual function in health and disease". J Hepatol 2015;62:1447-1448. doi: 10.1016/j.jhep.2015.02.013
    • (2015) J Hepatol , vol.62 , pp. 1447-1448
    • Zhang, X.J.1    Wang, P.X.2    Zhang, P.3    Li, H.4
  • 6
    • 77950355734 scopus 로고    scopus 로고
    • Anti-inflammatory Agents: Present and Future
    • Dinarello CA., Anti-inflammatory Agents: Present and Future. Cell 2010;140:935-950. doi: 10.1016/j.cell.2010.02.043
    • (2010) Cell , vol.140 , pp. 935-950
    • Dinarello, C.A.1
  • 7
    • 0036212849 scopus 로고    scopus 로고
    • Innate immune recognition
    • Janeway CA Jr, Medzhitov R., Innate immune recognition. Annu Rev Immunol 2002;20:197-216. doi: 10.1146/annurev.immunol.20.083001.084359
    • (2002) Annu Rev Immunol , vol.20 , pp. 197-216
    • Janeway, C.A.1    Medzhitov, R.2
  • 8
    • 42649114059 scopus 로고    scopus 로고
    • The IRF family transcription factors in immunity and oncogenesis
    • Tamura T, Yanai H, Savitsky D, Taniguchi T., The IRF family transcription factors in immunity and oncogenesis. Annu Rev Immunol 2008;26:535-584. doi: 10.1146/annurev.immunol.26.021607.090400
    • (2008) Annu Rev Immunol , vol.26 , pp. 535-584
    • Tamura, T.1    Yanai, H.2    Savitsky, D.3    Taniguchi, T.4
  • 9
    • 84919795881 scopus 로고    scopus 로고
    • Interferon regulatory factors: At the crossroads of immunity, metabolism, and disease
    • Zhao GN, Jiang DS, Li H., Interferon regulatory factors: At the crossroads of immunity, metabolism, and disease. Biochim Biophys Acta 2015;1852:365-378. doi: 10.1016/j.bbadis.2014.04.030
    • (2015) Biochim Biophys Acta , vol.1852 , pp. 365-378
    • Zhao, G.N.1    Jiang, D.S.2    Li, H.3
  • 10
    • 84949529544 scopus 로고    scopus 로고
    • Interferon regulatory factors as novel potential targets in the treatment of cardiovascular diseases
    • Zhang XJ, Jiang DS, Li H., Interferon regulatory factors as novel potential targets in the treatment of cardiovascular diseases. Br J Pharmacol 2014. doi: 10.1111/bph.12881
    • (2014) Br J Pharmacol
    • Zhang, X.J.1    Jiang, D.S.2    Li, H.3
  • 11
    • 77449101221 scopus 로고    scopus 로고
    • Regulation of immunity and oncogenesis by the IRF transcription factor family
    • Savitsky D, Tamura T, Yanai H, Taniguchi T., Regulation of immunity and oncogenesis by the IRF transcription factor family. Cancer Immunol Immunother 2010;59:489-510. doi: 10.1007/s00262-009-0804-6
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 489-510
    • Savitsky, D.1    Tamura, T.2    Yanai, H.3    Taniguchi, T.4
  • 12
    • 33748051738 scopus 로고    scopus 로고
    • IRFs: Master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
    • Honda K, Taniguchi T., IRFs: Master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol 2006;6:644-658. doi: 10.1038/nri1900
    • (2006) Nat Rev Immunol , vol.6 , pp. 644-658
    • Honda, K.1    Taniguchi, T.2
  • 13
    • 0033557741 scopus 로고    scopus 로고
    • Assembly requirements of PU.1-Pip (IRF-4) activator complexes: Inhibiting function in vivo using fused dimers
    • Brass AL, Zhu AQ, Singh H., Assembly requirements of PU.1-Pip (IRF-4) activator complexes: Inhibiting function in vivo using fused dimers. EMBO J 1999;18:977-991. doi: 10.1093/emboj/18.4.977
    • (1999) EMBO J , vol.18 , pp. 977-991
    • Brass, A.L.1    Zhu, A.Q.2    Singh, H.3
  • 14
    • 0033400453 scopus 로고    scopus 로고
    • Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4
    • Gupta S, Jiang M, Anthony A, Pernis AB., Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4. J Exp Med 1999;190:1837-1848.
    • (1999) J Exp Med , vol.190 , pp. 1837-1848
    • Gupta, S.1    Jiang, M.2    Anthony, A.3    Pernis, A.B.4
  • 15
    • 0036311933 scopus 로고    scopus 로고
    • Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes
    • Barnes BJ, Kellum MJ, Field AE, Pitha PM., Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes. Mol Cell Biol 2002;22:5721-5740.
    • (2002) Mol Cell Biol , vol.22 , pp. 5721-5740
    • Barnes, B.J.1    Kellum, M.J.2    Field, A.E.3    Pitha, P.M.4
  • 16
    • 0038608016 scopus 로고    scopus 로고
    • Virus-induced heterodimer formation between IRF-5 and IRF-7 modulates assembly of the IFNA enhanceosome in vivo and transcriptional activity of IFNA genes
    • Barnes BJ, Field AE, Pitha-Rowe PM., Virus-induced heterodimer formation between IRF-5 and IRF-7 modulates assembly of the IFNA enhanceosome in vivo and transcriptional activity of IFNA genes. J Biol Chem 2003;278:16630-16641. doi: 10.1074/jbc.M212609200
    • (2003) J Biol Chem , vol.278 , pp. 16630-16641
    • Barnes, B.J.1    Field, A.E.2    Pitha-Rowe, P.M.3
  • 17
    • 13444283466 scopus 로고    scopus 로고
    • Roles of interferon-regulatory factors in T-helper-cell differentiation
    • Lohoff M, Mak TW., Roles of interferon-regulatory factors in T-helper-cell differentiation. Nat Rev Immunol 2005;5:125-135. doi: 10.1038/nri1552
    • (2005) Nat Rev Immunol , vol.5 , pp. 125-135
    • Lohoff, M.1    Mak, T.W.2
  • 18
    • 0024380583 scopus 로고
    • Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes
    • Harada H, Fujita T, Miyamoto M, Kimura Y, Maruyama M, Furia A, Miyata T, Taniguchi T., Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell 1989;58:729-739.
    • (1989) Cell , vol.58 , pp. 729-739
    • Harada, H.1    Fujita, T.2    Miyamoto, M.3    Kimura, Y.4    Maruyama, M.5    Furia, A.6    Miyata, T.7    Taniguchi, T.8
  • 19
    • 0036176484 scopus 로고    scopus 로고
    • Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation
    • Reich NC., Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation. J Interferon Cytokine Res 2002;22:103-109. doi: 10.1089/107999002753452719
    • (2002) J Interferon Cytokine Res , vol.22 , pp. 103-109
    • Reich, N.C.1
  • 22
    • 0034686471 scopus 로고    scopus 로고
    • Interferon regulatory factor (IRF)-1 and IRF-2 regulate interferon gamma-dependent cyclooxygenase 2 expression
    • Blanco JC, Contursi C, Salkowski CA, DeWitt DL, Ozato K, Vogel SN., Interferon regulatory factor (IRF)-1 and IRF-2 regulate interferon gamma-dependent cyclooxygenase 2 expression. J Exp Med 2000;191:2131-2144.
    • (2000) J Exp Med , vol.191 , pp. 2131-2144
    • Blanco, J.C.1    Contursi, C.2    Salkowski, C.A.3    DeWitt, D.L.4    Ozato, K.5    Vogel, S.N.6
  • 23
    • 58149268052 scopus 로고    scopus 로고
    • Induction, function and regulation of IL-17-producing T cells
    • Mills KH., Induction, function and regulation of IL-17-producing T cells. Eur J Immunol 2008;38:2636-2649. doi: 10.1002/eji.200838535
    • (2008) Eur J Immunol , vol.38 , pp. 2636-2649
    • Mills, K.H.1
  • 24
    • 0141559412 scopus 로고    scopus 로고
    • Differential signaling by CpG DNA in DCs and B cells: Not just TLR9
    • Verthelyi D, Zeuner RA., Differential signaling by CpG DNA in DCs and B cells: Not just TLR9. Trends Immunol 2003;24:519-522.
    • (2003) Trends Immunol , vol.24 , pp. 519-522
    • Verthelyi, D.1    Zeuner, R.A.2
  • 25
    • 84908674558 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 as key element of the interferon signature in plasmacytoid dendritic cells from systemic lupus erythematosus patients: Novel genetic associations in the mexican mestizo population
    • Santana-de Anda K, Gomez-Martin D, Monsivais-Urenda AE, Salgado-Bustamante M, Gonzalez-Amaro R, Alcocer-Varela J., Interferon regulatory factor 3 as key element of the interferon signature in plasmacytoid dendritic cells from systemic lupus erythematosus patients: Novel genetic associations in the mexican mestizo population. Clin Exp Immunol 2014;178:428-437.
    • (2014) Clin Exp Immunol , vol.178 , pp. 428-437
    • Santana-de Anda, K.1    Gomez-Martin, D.2    Monsivais-Urenda, A.E.3    Salgado-Bustamante, M.4    Gonzalez-Amaro, R.5    Alcocer-Varela, J.6
  • 26
    • 23244464285 scopus 로고    scopus 로고
    • Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling
    • Kim KI, Malakhova OA, Hoebe K, Yan M, Beutler B, Zhang DE., Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling. J Immunol 2005;175:847-854.
    • (2005) J Immunol , vol.175 , pp. 847-854
    • Kim, K.I.1    Malakhova, O.A.2    Hoebe, K.3    Yan, M.4    Beutler, B.5    Zhang, D.E.6
  • 28
    • 84904397782 scopus 로고    scopus 로고
    • IRF4 at the crossroads of effector T-cell fate decision
    • Huber M, Lohoff M., IRF4 at the crossroads of effector T-cell fate decision. Eur J Immunol 2014;44:1886-1895. doi: 10.1002/eji.201344279
    • (2014) Eur J Immunol , vol.44 , pp. 1886-1895
    • Huber, M.1    Lohoff, M.2
  • 30
    • 52049093870 scopus 로고    scopus 로고
    • Interferon regulatory factor 4 and 8 in B-cell development
    • Lu R., Interferon regulatory factor 4 and 8 in B-cell development. Trends Immunol 2008;29:487-492. doi: 10.1016/j.it.2008.07.006
    • (2008) Trends Immunol , vol.29 , pp. 487-492
    • Lu, R.1
  • 32
    • 84922496108 scopus 로고    scopus 로고
    • Activation and function of interferon regulatory factor 5
    • Ryzhakov G, Eames HL, Udalova IA., Activation and function of interferon regulatory factor 5. J Interferon Cytokine Res 2015;35:71-78. doi: 10.1089/jir.2014.0023
    • (2015) J Interferon Cytokine Res , vol.35 , pp. 71-78
    • Ryzhakov, G.1    Eames, H.L.2    Udalova, I.A.3
  • 34
    • 84896347326 scopus 로고    scopus 로고
    • Interferon regulatory factor 5 and autoimmune lupus
    • Xu WD, Pan HF, Xu Y, Ye DQ., Interferon regulatory factor 5 and autoimmune lupus. Expert Rev Mol Med 2013 15 e6. doi: 10.1017/erm.2013.7
    • (2013) Expert Rev Mol Med , vol.15 , pp. e6
    • Xu, W.D.1    Pan, H.F.2    Xu, Y.3    Ye, D.Q.4
  • 38
    • 18644374446 scopus 로고    scopus 로고
    • Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes
    • Kondo S, Schutte BC, Richardson RJ, Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. Nat Genet 2002;32:285-289. doi: 10.1038/ng985
    • (2002) Nat Genet , vol.32 , pp. 285-289
    • Kondo, S.1    Schutte, B.C.2    Richardson, R.J.3
  • 41
    • 0032434924 scopus 로고    scopus 로고
    • Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7
    • Sato M, Hata N, Asagiri M, Nakaya T, Taniguchi T, Tanaka N., Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7. FEBS Lett 1998;441:106-110.
    • (1998) FEBS Lett , vol.441 , pp. 106-110
    • Sato, M.1    Hata, N.2    Asagiri, M.3    Nakaya, T.4    Taniguchi, T.5    Tanaka, N.6
  • 42
    • 0036179714 scopus 로고    scopus 로고
    • Structure and function of IRF-7
    • Zhang L, Pagano JS., Structure and function of IRF-7. J Interferon Cytokine Res 2002;22:95-101. doi: 10.1089/107999002753452700
    • (2002) J Interferon Cytokine Res , vol.22 , pp. 95-101
    • Zhang, L.1    Pagano, J.S.2
  • 43
    • 82955245641 scopus 로고    scopus 로고
    • Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis
    • Carmona FD, Gutala R, Simeón CP, Spanish Scleroderma Group Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis. Ann Rheum Dis 2012;71:114-119. doi: 10.1136/annrheumdis-2011-200275
    • (2012) Ann Rheum Dis , vol.71 , pp. 114-119
    • Carmona, F.D.1    Gutala, R.2    Simeón, C.P.3
  • 44
    • 30344462965 scopus 로고    scopus 로고
    • Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex
    • Kanno Y, Levi BZ, Tamura T, Ozato K., Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex. J Interferon Cytokine Res 2005;25:770-779. doi: 10.1089/jir.2005.25.770
    • (2005) J Interferon Cytokine Res , vol.25 , pp. 770-779
    • Kanno, Y.1    Levi, B.Z.2    Tamura, T.3    Ozato, K.4
  • 45
    • 0036178254 scopus 로고    scopus 로고
    • ICSBP/IRF-8: Its regulatory roles in the development of myeloid cells
    • Tamura T, Ozato K., ICSBP/IRF-8: Its regulatory roles in the development of myeloid cells. J Interferon Cytokine Res 2002;22:145-152. doi: 10.1089/107999002753452755
    • (2002) J Interferon Cytokine Res , vol.22 , pp. 145-152
    • Tamura, T.1    Ozato, K.2
  • 46
    • 33750839981 scopus 로고    scopus 로고
    • Stages of germinal center transit are defined by B cell transcription factor coexpression and relative abundance
    • Cattoretti G, Shaknovich R, Smith PM, Jäck HM, Murty VV, Alobeid B., Stages of germinal center transit are defined by B cell transcription factor coexpression and relative abundance. J Immunol 2006;177:6930-6939.
    • (2006) J Immunol , vol.177 , pp. 6930-6939
    • Cattoretti, G.1    Shaknovich, R.2    Smith, P.M.3    Jäck, H.M.4    Murty, V.V.5    Alobeid, B.6
  • 47
    • 79956279442 scopus 로고    scopus 로고
    • Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation
    • Ouyang X, Zhang R, Yang J, Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation. Nat Commun 2011;2:314. doi: 10.1038/ncomms1311
    • (2011) Nat Commun , vol.2 , pp. 314
    • Ouyang, X.1    Zhang, R.2    Yang, J.3
  • 49
    • 0025243645 scopus 로고
    • Interferon-dependent transcriptional activation: Signal transduction without second messenger involvement?
    • Levy D, Darnell JE Jr, Interferon-dependent transcriptional activation: Signal transduction without second messenger involvement? New Biol 1990;2:923-928.
    • (1990) New Biol , vol.2 , pp. 923-928
    • Levy, D.1    Darnell, J.E.2
  • 50
    • 84903904112 scopus 로고    scopus 로고
    • STAT2 and IRF9: Beyond ISGF3
    • Fink K, Grandvaux N., STAT2 and IRF9: Beyond ISGF3. JAKSTAT 2013 2 e27521. doi: 10.4161/jkst.27521
    • (2013) JAKSTAT , vol.2 , pp. e27521
    • Fink, K.1    Grandvaux, N.2
  • 51
    • 84904915021 scopus 로고    scopus 로고
    • The IRF family transcription factors at the interface of innate and adaptive immune responses
    • Ikushima H, Negishi H, Taniguchi T., The IRF family transcription factors at the interface of innate and adaptive immune responses. Cold Spring Harb Symp Quant Biol 2013;78:105-116. doi: 10.1101/sqb.2013.78.020321
    • (2013) Cold Spring Harb Symp Quant Biol , vol.78 , pp. 105-116
    • Ikushima, H.1    Negishi, H.2    Taniguchi, T.3
  • 52
    • 84904157420 scopus 로고    scopus 로고
    • Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells
    • Kwa MQ, Nguyen T, Huynh J, Ramnath D, De Nardo D, Lam PY, Reynolds EC, Hamilton JA, Sweet MJ, Scholz GM., Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells. J Biol Chem 2014;289:19758-19768. doi: 10.1074/jbc.M114.584540
    • (2014) J Biol Chem , vol.289 , pp. 19758-19768
    • Kwa, M.Q.1    Nguyen, T.2    Huynh, J.3    Ramnath, D.4    De Nardo, D.5    Lam, P.Y.6    Reynolds, E.C.7    Hamilton, J.A.8    Sweet, M.J.9    Scholz, G.M.10
  • 53
    • 33750064259 scopus 로고    scopus 로고
    • Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program
    • Negishi H, Fujita Y, Yanai H, Sakaguchi S, Ouyang X, Shinohara M, Takayanagi H, Ohba Y, Taniguchi T, Honda K., Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program. Proc Natl Acad Sci U S A 2006;103:15136-15141. doi: 10.1073/pnas.0607181103
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 15136-15141
    • Negishi, H.1    Fujita, Y.2    Yanai, H.3    Sakaguchi, S.4    Ouyang, X.5    Shinohara, M.6    Takayanagi, H.7    Ohba, Y.8    Taniguchi, T.9    Honda, K.10
  • 56
    • 33645841633 scopus 로고    scopus 로고
    • IκB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9
    • Hoshino K, Sugiyama T, Matsumoto M, Tanaka T, Saito M, Hemmi H, Ohara O, Akira S, Kaisho T., IκB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9. Nature 2006;440:949-953. doi: 10.1038/nature04641
    • (2006) Nature , vol.440 , pp. 949-953
    • Hoshino, K.1    Sugiyama, T.2    Matsumoto, M.3    Tanaka, T.4    Saito, M.5    Hemmi, H.6    Ohara, O.7    Akira, S.8    Kaisho, T.9
  • 57
    • 2442689141 scopus 로고    scopus 로고
    • Toll-like receptor 9 signaling activates NF-κB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells
    • Tsujimura H, Tamura T, Kong HJ, Nishiyama A, Ishii KJ, Klinman DM, Ozato K., Toll-like receptor 9 signaling activates NF-κB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells. J Immunol 2004;172:6820-6827.
    • (2004) J Immunol , vol.172 , pp. 6820-6827
    • Tsujimura, H.1    Tamura, T.2    Kong, H.J.3    Nishiyama, A.4    Ishii, K.J.5    Klinman, D.M.6    Ozato, K.7
  • 58
    • 33744539146 scopus 로고    scopus 로고
    • IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways
    • Zhao J, Kong HJ, Li H, Huang B, Yang M, Zhu C, Bogunovic M, Zheng F, Mayer L, Ozato K, Unkeless J, Xiong H., IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. J Biol Chem 2006;281:10073-10080. doi: 10.1074/jbc.M507788200
    • (2006) J Biol Chem , vol.281 , pp. 10073-10080
    • Zhao, J.1    Kong, H.J.2    Li, H.3    Huang, B.4    Yang, M.5    Zhu, C.6    Bogunovic, M.7    Zheng, F.8    Mayer, L.9    Ozato, K.10    Unkeless, J.11    Xiong, H.12
  • 63
    • 28644433321 scopus 로고    scopus 로고
    • SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways
    • Huang J, Liu T, Xu LG, Chen D, Zhai Z, Shu HB., SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways. EMBO J 2005;24:4018-4028. doi: 10.1038/sj.emboj.7600863
    • (2005) EMBO J , vol.24 , pp. 4018-4028
    • Huang, J.1    Liu, T.2    Xu, L.G.3    Chen, D.4    Zhai, Z.5    Shu, H.B.6
  • 65
    • 0346496019 scopus 로고    scopus 로고
    • The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens
    • He YW, Li H, Zhang J, Hsu CL, Lin E, Zhang N, Guo J, Forbush KA, Bevan MJ., The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens. Nat Immunol 2004;5:88-97. doi: 10.1038/ni1021
    • (2004) Nat Immunol , vol.5 , pp. 88-97
    • He, Y.W.1    Li, H.2    Zhang, J.3    Hsu, C.L.4    Lin, E.5    Zhang, N.6    Guo, J.7    Forbush, K.A.8    Bevan, M.J.9
  • 66
    • 84879602096 scopus 로고    scopus 로고
    • Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. Albicans
    • del Fresno C, Soulat D, Roth S, Blazek K, Udalova I, Sancho D, Ruland J, Ardavín C., Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans. Immunity 2013;38:1176-1186. doi: 10.1016/j.immuni.2013.05.010
    • (2013) Immunity , vol.38 , pp. 1176-1186
    • Del Fresno, C.1    Soulat, D.2    Roth, S.3    Blazek, K.4    Udalova, I.5    Sancho, D.6    Ruland, J.7    Ardavín, C.8
  • 67
    • 77249132637 scopus 로고    scopus 로고
    • Recognition of viruses by cytoplasmic sensors
    • Wilkins C, Gale M Jr, Recognition of viruses by cytoplasmic sensors. Curr Opin Immunol 2010;22:41-47. doi: 10.1016/j.coi.2009.12.003
    • (2010) Curr Opin Immunol , vol.22 , pp. 41-47
    • Wilkins, C.1    Gale, M.2
  • 68
    • 0038363463 scopus 로고    scopus 로고
    • Triggering the interferon antiviral response through an IKK-related pathway
    • Sharma S, tenOever BR, Grandvaux N, Zhou GP, Lin R, Hiscott J., Triggering the interferon antiviral response through an IKK-related pathway. Science 2003;300:1148-1151. doi: 10.1126/science.1081315
    • (2003) Science , vol.300 , pp. 1148-1151
    • Sharma, S.1    TenOever, B.R.2    Grandvaux, N.3    Zhou, G.P.4    Lin, R.5    Hiscott, J.6
  • 69
    • 33644850482 scopus 로고    scopus 로고
    • Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20
    • Lin R, Yang L, Nakhaei P, Sun Q, Sharif-Askari E, Julkunen I, Hiscott J., Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20. J Biol Chem 2006;281:2095-2103. doi: 10.1074/jbc.M510326200
    • (2006) J Biol Chem , vol.281 , pp. 2095-2103
    • Lin, R.1    Yang, L.2    Nakhaei, P.3    Sun, Q.4    Sharif-Askari, E.5    Julkunen, I.6    Hiscott, J.7
  • 72
    • 84857846174 scopus 로고    scopus 로고
    • Activation of interferon regulatory factor 5 by site specific phosphorylation
    • Chang Foreman HC, Van Scoy S, Cheng TF, Reich NC., Activation of interferon regulatory factor 5 by site specific phosphorylation. PLoS One 2012 7 e33098. doi: 10.1371/journal.pone.0033098
    • (2012) PLoS One , vol.7 , pp. e33098
    • Chang Foreman, H.C.1    Van Scoy, S.2    Cheng, T.F.3    Reich, N.C.4
  • 73
    • 30444450839 scopus 로고    scopus 로고
    • Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
    • Stetson DB, Medzhitov R., Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 2006;24:93-103. doi: 10.1016/j.immuni.2005.12.003
    • (2006) Immunity , vol.24 , pp. 93-103
    • Stetson, D.B.1    Medzhitov, R.2
  • 74
    • 0035061538 scopus 로고    scopus 로고
    • IRF family of transcription factors as regulators of host defense
    • Taniguchi T, Ogasawara K, Takaoka A, Tanaka N., IRF family of transcription factors as regulators of host defense. Annu Rev Immunol 2001;19:623-655. doi: 10.1146/annurev.immunol.19.1.623
    • (2001) Annu Rev Immunol , vol.19 , pp. 623-655
    • Taniguchi, T.1    Ogasawara, K.2    Takaoka, A.3    Tanaka, N.4
  • 75
    • 0034948757 scopus 로고    scopus 로고
    • The interferon system and interferon regulatory factor transcription factors - studies from gene knockout mice
    • Sato M, Taniguchi T, Tanaka N., The interferon system and interferon regulatory factor transcription factors-studies from gene knockout mice. Cytokine Growth Factor Rev 2001;12:133-142.
    • (2001) Cytokine Growth Factor Rev , vol.12 , pp. 133-142
    • Sato, M.1    Taniguchi, T.2    Tanaka, N.3
  • 76
    • 19344375679 scopus 로고    scopus 로고
    • A cytomegaloviral protein reveals a dual role for STAT2 in IFN-γ signaling and antiviral responses
    • Zimmermann A, Trilling M, Wagner M, Wilborn M, Bubic I, Jonjic S, Koszinowski U, Hengel H., A cytomegaloviral protein reveals a dual role for STAT2 in IFN-γ signaling and antiviral responses. J Exp Med 2005;201:1543-1553. doi: 10.1084/jem.20041401
    • (2005) J Exp Med , vol.201 , pp. 1543-1553
    • Zimmermann, A.1    Trilling, M.2    Wagner, M.3    Wilborn, M.4    Bubic, I.5    Jonjic, S.6    Koszinowski, U.7    Hengel, H.8
  • 77
    • 84908267694 scopus 로고    scopus 로고
    • InTRIMsic immunity: Positive and negative regulation of immune signaling by tripartite motif proteins
    • Versteeg GA, Benke S, García-Sastre A, Rajsbaum R., InTRIMsic immunity: Positive and negative regulation of immune signaling by tripartite motif proteins. Cytokine Growth Factor Rev 2014;25:563-576. doi: 10.1016/j.cytogfr.2014.08.001
    • (2014) Cytokine Growth Factor Rev , vol.25 , pp. 563-576
    • Versteeg, G.A.1    Benke, S.2    García-Sastre, A.3    Rajsbaum, R.4
  • 78
    • 0035444577 scopus 로고    scopus 로고
    • Complete suppression of insulitis and diabetes in NOD mice lacking interferon regulatory factor-1
    • Nakazawa T, Satoh J, Takahashi K, Complete suppression of insulitis and diabetes in NOD mice lacking interferon regulatory factor-1. J Autoimmun 2001;17:119-125. doi: 10.1006/jaut.2001.0531
    • (2001) J Autoimmun , vol.17 , pp. 119-125
    • Nakazawa, T.1    Satoh, J.2    Takahashi, K.3
  • 80
    • 0037712882 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 immunoreactivity in neurons and inflammatory cells following ischemic stroke in rodents and humans
    • Alexander M, Forster C, Sugimoto K, Clark HB, Vogel S, Ross ME, Iadecola C., Interferon regulatory factor-1 immunoreactivity in neurons and inflammatory cells following ischemic stroke in rodents and humans. Acta Neuropathol 2003;105:420-424. doi: 10.1007/s00401-002-0658-x
    • (2003) Acta Neuropathol , vol.105 , pp. 420-424
    • Alexander, M.1    Forster, C.2    Sugimoto, K.3    Clark, H.B.4    Vogel, S.5    Ross, M.E.6    Iadecola, C.7
  • 82
    • 0023788435 scopus 로고
    • Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements
    • Miyamoto M, Fujita T, Kimura Y, Maruyama M, Harada H, Sudo Y, Miyata T, Taniguchi T., Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements. Cell 1988;54:903-913.
    • (1988) Cell , vol.54 , pp. 903-913
    • Miyamoto, M.1    Fujita, T.2    Kimura, Y.3    Maruyama, M.4    Harada, H.5    Sudo, Y.6    Miyata, T.7    Taniguchi, T.8
  • 85
    • 84872298261 scopus 로고    scopus 로고
    • High mobility group Box 1 inhibits human pulmonary artery endothelial cell migration via a Toll-like receptor 4- and interferon response factor 3-dependent mechanism(s)
    • Bauer EM, Shapiro R, Billiar TR, Bauer PM., High mobility group Box 1 inhibits human pulmonary artery endothelial cell migration via a Toll-like receptor 4- and interferon response factor 3-dependent mechanism(s). J Biol Chem 2013;288:1365-1373. doi: 10.1074/jbc.M112.434142
    • (2013) J Biol Chem , vol.288 , pp. 1365-1373
    • Bauer, E.M.1    Shapiro, R.2    Billiar, T.R.3    Bauer, P.M.4
  • 87
    • 0029618697 scopus 로고
    • Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes
    • Au WC, Moore PA, Lowther W, Juang YT, Pitha PM., Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes. Proc Natl Acad Sci U S A 1995;92:11657-11661.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 11657-11661
    • Au, W.C.1    Moore, P.A.2    Lowther, W.3    Juang, Y.T.4    Pitha, P.M.5
  • 88
    • 84888131271 scopus 로고    scopus 로고
    • Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization
    • Eguchi J, Kong X, Tenta M, Wang X, Kang S, Rosen ED., Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization. Diabetes 2013;62:3394-3403. doi: 10.2337/db12-1327
    • (2013) Diabetes , vol.62 , pp. 3394-3403
    • Eguchi, J.1    Kong, X.2    Tenta, M.3    Wang, X.4    Kang, S.5    Rosen, E.D.6
  • 89
    • 84903989695 scopus 로고    scopus 로고
    • IRF4 is a key thermogenic transcriptional partner of PGC-1α
    • Kong X, Banks A, Liu T, IRF4 is a key thermogenic transcriptional partner of PGC-1α. Cell 2014;158:69-83. doi: 10.1016/j.cell.2014.04.049
    • (2014) Cell , vol.158 , pp. 69-83
    • Kong, X.1    Banks, A.2    Liu, T.3
  • 90
    • 84876523418 scopus 로고    scopus 로고
    • Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension
    • Lenna S, Farina AG, Martyanov V, Christmann RB, Wood TA, Farber HW, Scorza R, Whitfield ML, Lafyatis R, Trojanowska M., Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension. Arthritis Rheum 2013;65:1357-1366. doi: 10.1002/art.37891
    • (2013) Arthritis Rheum , vol.65 , pp. 1357-1366
    • Lenna, S.1    Farina, A.G.2    Martyanov, V.3    Christmann, R.B.4    Wood, T.A.5    Farber, H.W.6    Scorza, R.7    Whitfield, M.L.8    Lafyatis, R.9    Trojanowska, M.10
  • 93
    • 84900844706 scopus 로고    scopus 로고
    • In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing
    • Courties G, Heidt T, Sebas M, In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing. J Am Coll Cardiol 2014;63:1556-1566. doi: 10.1016/j.jacc.2013.11.023
    • (2014) J Am Coll Cardiol , vol.63 , pp. 1556-1566
    • Courties, G.1    Heidt, T.2    Sebas, M.3
  • 94
    • 0035968246 scopus 로고    scopus 로고
    • Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes
    • Barnes BJ, Moore PA, Pitha PM., Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes. J Biol Chem 2001;276:23382-23390. doi: 10.1074/jbc.M101216200
    • (2001) J Biol Chem , vol.276 , pp. 23382-23390
    • Barnes, B.J.1    Moore, P.A.2    Pitha, P.M.3
  • 97
    • 84897045727 scopus 로고    scopus 로고
    • Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy
    • Jiang DS, Liu Y, Zhou H, Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy. Hypertension 2014;63:713-722. doi: 10.1161/HYPERTENSIONAHA.113.02653
    • (2014) Hypertension , vol.63 , pp. 713-722
    • Jiang, D.S.1    Liu, Y.2    Zhou, H.3
  • 99
    • 0030820054 scopus 로고    scopus 로고
    • IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency
    • Zhang L, Pagano JS., IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency. Mol Cell Biol 1997;17:5748-5757.
    • (1997) Mol Cell Biol , vol.17 , pp. 5748-5757
    • Zhang, L.1    Pagano, J.S.2
  • 101
    • 84894057277 scopus 로고    scopus 로고
    • IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling
    • Jiang DS, Wei X, Zhang XF, IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling. Nat Commun 2014;5:3303. doi: 10.1038/ncomms4303
    • (2014) Nat Commun , vol.5 , pp. 3303
    • Jiang, D.S.1    Wei, X.2    Zhang, X.F.3
  • 103
    • 84881030779 scopus 로고    scopus 로고
    • Interferon regulatory factor 9 protects against hepatic insulin resistance and steatosis in male mice
    • Wang XA, Zhang R, Jiang D, Interferon regulatory factor 9 protects against hepatic insulin resistance and steatosis in male mice. Hepatology 2013;58:603-616. doi: 10.1002/hep.26368
    • (2013) Hepatology , vol.58 , pp. 603-616
    • Wang, X.A.1    Zhang, R.2    Jiang, D.3
  • 106
    • 84855858769 scopus 로고    scopus 로고
    • Loss of regulator of G protein signaling 5 exacerbates obesity, hepatic steatosis, inflammation and insulin resistance
    • Deng W, Wang X, Xiao J, Chen K, Zhou H, Shen D, Li H, Tang Q., Loss of regulator of G protein signaling 5 exacerbates obesity, hepatic steatosis, inflammation and insulin resistance. PLoS One 2012 7 e30256. doi: 10.1371/journal.pone.0030256
    • (2012) PLoS One , vol.7 , pp. e30256
    • Deng, W.1    Wang, X.2    Xiao, J.3    Chen, K.4    Zhou, H.5    Shen, D.6    Li, H.7    Tang, Q.8
  • 107
    • 40549135297 scopus 로고    scopus 로고
    • Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: Lessons from genetically engineered mice
    • Postic C, Girard J., Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: Lessons from genetically engineered mice. J Clin Invest 2008;118:829-838. doi: 10.1172/JCI34275
    • (2008) J Clin Invest , vol.118 , pp. 829-838
    • Postic, C.1    Girard, J.2
  • 108
    • 0037900979 scopus 로고    scopus 로고
    • Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors
    • Lee CH, Olson P, Evans RM., Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology 2003;144:2201-2207. doi: 10.1210/en.2003-0288
    • (2003) Endocrinology , vol.144 , pp. 2201-2207
    • Lee, C.H.1    Olson, P.2    Evans, R.M.3
  • 109
    • 75449094816 scopus 로고    scopus 로고
    • Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications
    • Fabbrini E, Sullivan S, Klein S., Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications. Hepatology 2010;51:679-689. doi: 10.1002/hep.23280
    • (2010) Hepatology , vol.51 , pp. 679-689
    • Fabbrini, E.1    Sullivan, S.2    Klein, S.3
  • 110
    • 0035024343 scopus 로고    scopus 로고
    • A potent PPARalpha agonist stimulates mitochondrial fatty acid beta-oxidation in liver and skeletal muscle
    • Minnich A, Tian N, Byan L, Bilder G., A potent PPARalpha agonist stimulates mitochondrial fatty acid beta-oxidation in liver and skeletal muscle. Am J Physiol Endocrinol Metab 2001 280 E270 E279
    • (2001) Am J Physiol Endocrinol Metab , vol.280 , pp. E270-E279
    • Minnich, A.1    Tian, N.2    Byan, L.3    Bilder, G.4
  • 111
    • 24744457984 scopus 로고    scopus 로고
    • Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation
    • Fu Y, Luo N, Klein RL, Garvey WT., Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation. J Lipid Res 2005;46:1369-1379. doi: 10.1194/jlr.M400373-JLR200
    • (2005) J Lipid Res , vol.46 , pp. 1369-1379
    • Fu, Y.1    Luo, N.2    Klein, R.L.3    Garvey, W.T.4
  • 112
    • 0034685589 scopus 로고    scopus 로고
    • Activation of PPARdelta alters lipid metabolism in db/Db mice
    • Leibowitz MD, Fiévet C, Hennuyer N, Activation of PPARdelta alters lipid metabolism in db/db mice. FEBS Lett 2000;473:333-336.
    • (2000) FEBS Lett , vol.473 , pp. 333-336
    • Leibowitz, M.D.1    Fiévet, C.2    Hennuyer, N.3
  • 113
    • 78650878363 scopus 로고    scopus 로고
    • NF-κB, inflammation, and metabolic disease
    • Baker RG, Hayden MS, Ghosh S., NF-κB, inflammation, and metabolic disease. Cell Metab 2011;13:11-22. doi: 10.1016/j.cmet.2010.12.008
    • (2011) Cell Metab , vol.13 , pp. 11-22
    • Baker, R.G.1    Hayden, M.S.2    Ghosh, S.3
  • 114
    • 67650914230 scopus 로고    scopus 로고
    • AMPK in Health and Disease
    • Steinberg GR, Kemp BE., AMPK in Health and Disease. Physiol Rev 2009;89:1025-1078. doi: 10.1152/physrev.00011.2008
    • (2009) Physiol Rev , vol.89 , pp. 1025-1078
    • Steinberg, G.R.1    Kemp, B.E.2
  • 118
    • 84937548844 scopus 로고    scopus 로고
    • Regulatory function of interferon regulatory factor 3 in obesity, inflammation and insulin resistance
    • Tang P, Zhang Y., Regulatory function of interferon regulatory factor 3 in obesity, inflammation and insulin resistance. J Immunol 2014;192.
    • (2014) J Immunol , pp. 192
    • Tang, P.1    Zhang, Y.2
  • 119
    • 79955611314 scopus 로고    scopus 로고
    • Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice
    • Kim S, Jin Y, Choi Y, Park T., Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice. Biochem Pharmacol 2011;81:1343-1351. doi: 10.1016/j.bcp.2011.03.012
    • (2011) Biochem Pharmacol , vol.81 , pp. 1343-1351
    • Kim, S.1    Jin, Y.2    Choi, Y.3    Park, T.4
  • 120
    • 84901337869 scopus 로고    scopus 로고
    • IL-21 is a major negative regulator of IRF4-dependent lipolysis affecting Tregs in adipose tissue and systemic insulin sensitivity
    • Fabrizi M, Marchetti V, Mavilio M, IL-21 is a major negative regulator of IRF4-dependent lipolysis affecting Tregs in adipose tissue and systemic insulin sensitivity. Diabetes 2014;63:2086-2096. doi: 10.2337/db13-0939
    • (2014) Diabetes , vol.63 , pp. 2086-2096
    • Fabrizi, M.1    Marchetti, V.2    Mavilio, M.3
  • 121
    • 84901347132 scopus 로고    scopus 로고
    • IL-21 and IRF4: A complex partnership in immune and metabolic regulation
    • Knudsen NH, Lee CH., IL-21 and IRF4: A complex partnership in immune and metabolic regulation. Diabetes 2014;63:1838-1840. doi: 10.2337/db14-0273
    • (2014) Diabetes , vol.63 , pp. 1838-1840
    • Knudsen, N.H.1    Lee, C.H.2
  • 123
    • 0038644820 scopus 로고    scopus 로고
    • A hybrid IRF9-STAT2 protein recapitulates interferon-stimulated gene expression and antiviral response
    • Kraus TA, Lau JF, Parisien JP, Horvath CM., A hybrid IRF9-STAT2 protein recapitulates interferon-stimulated gene expression and antiviral response. J Biol Chem 2003;278:13033-13038. doi: 10.1074/jbc.M212972200
    • (2003) J Biol Chem , vol.278 , pp. 13033-13038
    • Kraus, T.A.1    Lau, J.F.2    Parisien, J.P.3    Horvath, C.M.4
  • 124
    • 0036851826 scopus 로고    scopus 로고
    • Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies
    • Dzau VJ, Braun-Dullaeus RC, Sedding DG., Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies. Nat Med 2002;8:1249-1256. doi: 10.1038/nm1102-1249
    • (2002) Nat Med , vol.8 , pp. 1249-1256
    • Dzau, V.J.1    Braun-Dullaeus, R.C.2    Sedding, D.G.3
  • 125
  • 127
    • 74149093839 scopus 로고    scopus 로고
    • Puerarin attenuates high-glucose-and diabetes-induced vascular smooth muscle cell proliferation by blocking PKCbeta2/Rac1-dependent signaling
    • Zhu LH, Wang L, Wang D, Jiang H, Tang QZ, Yan L, Bian ZY, Wang XA, Li H., Puerarin attenuates high-glucose-and diabetes-induced vascular smooth muscle cell proliferation by blocking PKCbeta2/Rac1-dependent signaling. Free Radic Biol Med 2010;48:471-482. doi: 10.1016/j.freeradbiomed.2009.10.040
    • (2010) Free Radic Biol Med , vol.48 , pp. 471-482
    • Zhu, L.H.1    Wang, L.2    Wang, D.3    Jiang, H.4    Tang, Q.Z.5    Yan, L.6    Bian, Z.Y.7    Wang, X.A.8    Li, H.9
  • 128
    • 80054926880 scopus 로고    scopus 로고
    • Micromanaging vascular smooth muscle cell differentiation and phenotypic modulation
    • Davis-Dusenbery BN, Wu C, Hata A., Micromanaging vascular smooth muscle cell differentiation and phenotypic modulation. Arterioscler Thromb Vasc Biol 2011;31:2370-2377. doi: 10.1161/ATVBAHA.111.226670
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 2370-2377
    • Davis-Dusenbery, B.N.1    Wu, C.2    Hata, A.3
  • 129
    • 12844286997 scopus 로고    scopus 로고
    • Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture
    • Newby AC., Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture. Physiol Rev 2005;85:1-31. doi: 10.1152/physrev.00048.2003
    • (2005) Physiol Rev , vol.85 , pp. 1-31
    • Newby, A.C.1
  • 130
    • 80054993002 scopus 로고    scopus 로고
    • Vascular inflammation and repair: Implications for re-endothelialization, restenosis, and stent thrombosis
    • Inoue T, Croce K, Morooka T, Sakuma M, Node K, Simon DI., Vascular inflammation and repair: Implications for re-endothelialization, restenosis, and stent thrombosis. JACC Cardiovasc Interv 2011;4:1057-1066. doi: 10.1016/j.jcin.2011.05.025
    • (2011) JACC Cardiovasc Interv , vol.4 , pp. 1057-1066
    • Inoue, T.1    Croce, K.2    Morooka, T.3    Sakuma, M.4    Node, K.5    Simon, D.I.6
  • 131
    • 84857293493 scopus 로고    scopus 로고
    • Epigenetic control of smooth muscle cell differentiation and phenotypic switching in vascular development and disease
    • Alexander MR, Owens GK., Epigenetic control of smooth muscle cell differentiation and phenotypic switching in vascular development and disease. Annu Rev Physiol 2012;74:13-40. doi: 10.1146/annurev-physiol-012110-142315
    • (2012) Annu Rev Physiol , vol.74 , pp. 13-40
    • Alexander, M.R.1    Owens, G.K.2
  • 132
    • 0034601755 scopus 로고    scopus 로고
    • Roles of P-selectin in inflammation, neointimal formation, and vascular remodeling in balloon-injured rat carotid arteries
    • Hayashi S, Watanabe N, Nakazawa K, Suzuki J, Tsushima K, Tamatani T, Sakamoto S, Isobe M., Roles of P-selectin in inflammation, neointimal formation, and vascular remodeling in balloon-injured rat carotid arteries. Circulation 2000;102:1710-1717.
    • (2000) Circulation , vol.102 , pp. 1710-1717
    • Hayashi, S.1    Watanabe, N.2    Nakazawa, K.3    Suzuki, J.4    Tsushima, K.5    Tamatani, T.6    Sakamoto, S.7    Isobe, M.8
  • 134
    • 34748871414 scopus 로고    scopus 로고
    • Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation
    • Wang Y, Bai Y, Qin L, Zhang P, Yi T, Teesdale SA, Zhao L, Pober JS, Tellides G., Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation. Circ Res 2007;101:560-569. doi: 10.1161/CIRCRESAHA.107.151068
    • (2007) Circ Res , vol.101 , pp. 560-569
    • Wang, Y.1    Bai, Y.2    Qin, L.3    Zhang, P.4    Yi, T.5    Teesdale, S.A.6    Zhao, L.7    Pober, J.S.8    Tellides, G.9
  • 135
    • 34047219787 scopus 로고    scopus 로고
    • Inhibition of intrinsic interferon-gamma function prevents neointima formation after balloon injury
    • Kusaba K, Kai H, Koga M, Takayama N, Ikeda A, Yasukawa H, Seki Y, Egashira K, Imaizumi T., Inhibition of intrinsic interferon-gamma function prevents neointima formation after balloon injury. Hypertension 2007;49:909-915. doi: 10.1161/01.HYP.0000259668.37901.8c
    • (2007) Hypertension , vol.49 , pp. 909-915
    • Kusaba, K.1    Kai, H.2    Koga, M.3    Takayama, N.4    Ikeda, A.5    Yasukawa, H.6    Seki, Y.7    Egashira, K.8    Imaizumi, T.9
  • 138
    • 0037010005 scopus 로고    scopus 로고
    • Oral tolerance with heat shock protein 65 attenuates Mycobacterium tuberculosis-induced and high-fat-diet-driven atherosclerotic lesions
    • Harats D, Yacov N, Gilburd B, Shoenfeld Y, George J., Oral tolerance with heat shock protein 65 attenuates Mycobacterium tuberculosis-induced and high-fat-diet-driven atherosclerotic lesions. J Am Coll Cardiol 2002;40:1333-1338.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 1333-1338
    • Harats, D.1    Yacov, N.2    Gilburd, B.3    Shoenfeld, Y.4    George, J.5
  • 140
    • 0026474273 scopus 로고
    • Induction of PDGF-responsive genes in vascular smooth muscle. Implications for the early response to vessel injury
    • Marmur JD, Poon M, Rossikhina M, Taubman MB., Induction of PDGF-responsive genes in vascular smooth muscle. Implications for the early response to vessel injury. Circulation 1992;86:III53-III60.
    • (1992) Circulation , vol.86 , pp. III53-III60
    • Marmur, J.D.1    Poon, M.2    Rossikhina, M.3    Taubman, M.B.4
  • 141
    • 0038417515 scopus 로고    scopus 로고
    • Clinical utility of endothelial function testing: Ready for prime time?
    • Kuvin JT, Karas RH., Clinical utility of endothelial function testing: Ready for prime time? Circulation 2003;107:3243-3247. doi: 10.1161/01.CIR.0000075928.54461.33
    • (2003) Circulation , vol.107 , pp. 3243-3247
    • Kuvin, J.T.1    Karas, R.H.2
  • 142
    • 79956218655 scopus 로고    scopus 로고
    • The inflammatory response to double stranded DNA in endothelial cells is mediated by NFκB and TNFα
    • Patel SJ, Jindal R, King KR, Tilles AW, Yarmush ML., The inflammatory response to double stranded DNA in endothelial cells is mediated by NFκB and TNFα. PLoS One 2011 6 e19910. doi: 10.1371/journal.pone.0019910
    • (2011) PLoS One , vol.6 , pp. e19910
    • Patel, S.J.1    Jindal, R.2    King, K.R.3    Tilles, A.W.4    Yarmush, M.L.5
  • 143
    • 54349126568 scopus 로고    scopus 로고
    • Molecular characterization of IRF3 and IRF7 in rainbow trout, Oncorhynchus mykiss: Functional analysis and transcriptional modulation
    • Holland JW, Bird S, Williamson B, Woudstra C, Mustafa A, Wang T, Zou J, Blaney SC, Collet B, Secombes CJ., Molecular characterization of IRF3 and IRF7 in rainbow trout, Oncorhynchus mykiss: Functional analysis and transcriptional modulation. Mol Immunol 2008;46:269-285. doi: 10.1016/j.molimm.2008.08.265
    • (2008) Mol Immunol , vol.46 , pp. 269-285
    • Holland, J.W.1    Bird, S.2    Williamson, B.3    Woudstra, C.4    Mustafa, A.5    Wang, T.6    Zou, J.7    Blaney, S.C.8    Collet, B.9    Secombes, C.J.10
  • 144
    • 0142186757 scopus 로고    scopus 로고
    • IFN-alpha and IL-12 activate IFN regulatory factor 1 (IRF-1), IRF-4, and IRF-8 gene expression in human NK and T cells
    • Lehtonen A, Lund R, Lahesmaa R, Julkunen I, Sareneva T, Matikainen S., IFN-alpha and IL-12 activate IFN regulatory factor 1 (IRF-1), IRF-4, and IRF-8 gene expression in human NK and T cells. Cytokine 2003;24:81-90.
    • (2003) Cytokine , vol.24 , pp. 81-90
    • Lehtonen, A.1    Lund, R.2    Lahesmaa, R.3    Julkunen, I.4    Sareneva, T.5    Matikainen, S.6
  • 147
    • 79957463838 scopus 로고    scopus 로고
    • SIRT1 acts as a modulator of neointima formation following vascular injury in mice
    • Li L, Zhang HN, Chen HZ, SIRT1 acts as a modulator of neointima formation following vascular injury in mice. Circ Res 2011;108:1180-1189. doi: 10.1161/CIRCRESAHA.110.237875
    • (2011) Circ Res , vol.108 , pp. 1180-1189
    • Li, L.1    Zhang, H.N.2    Chen, H.Z.3
  • 148
    • 0036733629 scopus 로고    scopus 로고
    • Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms
    • Longo GM, Xiong W, Greiner TC, Zhao Y, Fiotti N, Baxter BT., Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest 2002;110:625-632. doi: 10.1172/JCI15334
    • (2002) J Clin Invest , vol.110 , pp. 625-632
    • Longo, G.M.1    Xiong, W.2    Greiner, T.C.3    Zhao, Y.4    Fiotti, N.5    Baxter, B.T.6
  • 149
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • Heineke J, Molkentin JD., Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 2006;7:589-600. doi: 10.1038/nrm1983
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 152
    • 0034720847 scopus 로고    scopus 로고
    • Left ventricular remodeling after myocardial infarction: Pathophysiology and therapy
    • Sutton MG, Sharpe N., Left ventricular remodeling after myocardial infarction: Pathophysiology and therapy. Circulation 2000;101:2981-2988.
    • (2000) Circulation , vol.101 , pp. 2981-2988
    • Sutton, M.G.1    Sharpe, N.2
  • 154
    • 34249283088 scopus 로고    scopus 로고
    • Overexpression of myofibrillogenesis regulator-1 aggravates cardiac hypertrophy induced by angiotensin II in mice
    • Li HL, She ZG, Li TB, Wang AB, Yang Q, Wei YS, Wang YG, Liu DP., Overexpression of myofibrillogenesis regulator-1 aggravates cardiac hypertrophy induced by angiotensin II in mice. Hypertension 2007;49:1399-1408. doi: 10.1161/HYPERTENSIONAHA.106.085399
    • (2007) Hypertension , vol.49 , pp. 1399-1408
    • Li, H.L.1    She, Z.G.2    Li, T.B.3    Wang, A.B.4    Yang, Q.5    Wei, Y.S.6    Wang, Y.G.7    Liu, D.P.8
  • 155
    • 74949112895 scopus 로고    scopus 로고
    • LIM and cysteine-rich domains 1 regulates cardiac hypertrophy by targeting calcineurin/nuclear factor of activated T cells signaling
    • Bian ZY, Huang H, Jiang H, Shen DF, Yan L, Zhu LH, Wang L, Cao F, Liu C, Tang QZ, Li H., LIM and cysteine-rich domains 1 regulates cardiac hypertrophy by targeting calcineurin/nuclear factor of activated T cells signaling. Hypertension 2010;55:257-263. doi: 10.1161/HYPERTENSIONAHA.109.135665
    • (2010) Hypertension , vol.55 , pp. 257-263
    • Bian, Z.Y.1    Huang, H.2    Jiang, H.3    Shen, D.F.4    Yan, L.5    Zhu, L.H.6    Wang, L.7    Cao, F.8    Liu, C.9    Tang, Q.Z.10    Li, H.11
  • 156
    • 84896989506 scopus 로고    scopus 로고
    • Dickkopf-3 attenuates pressure overload-induced cardiac remodelling
    • Zhang Y, Liu Y, Zhu XH, Dickkopf-3 attenuates pressure overload-induced cardiac remodelling. Cardiovasc Res 2014;102:35-45. doi: 10.1093/cvr/cvu004
    • (2014) Cardiovasc Res , vol.102 , pp. 35-45
    • Zhang, Y.1    Liu, Y.2    Zhu, X.H.3
  • 158
    • 79960413821 scopus 로고    scopus 로고
    • Signature microRNA expression profile of essential hypertension and its novel link to human cytomegalovirus infection
    • Li S, Zhu J, Zhang W, Signature microRNA expression profile of essential hypertension and its novel link to human cytomegalovirus infection. Circulation 2011;124:175-184. doi: 10.1161/CIRCULATIONAHA.110.012237
    • (2011) Circulation , vol.124 , pp. 175-184
    • Li, S.1    Zhu, J.2    Zhang, W.3
  • 159
    • 0025770664 scopus 로고
    • Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system
    • Weber KT, Brilla CG., Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system. Circulation 1991;83:1849-1865.
    • (1991) Circulation , vol.83 , pp. 1849-1865
    • Weber, K.T.1    Brilla, C.G.2
  • 161
    • 84872013157 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy
    • Lu J, Bian ZY, Zhang R, Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy. Basic Res Cardiol 2013;108:326. doi: 10.1007/s00395-012-0326-9
    • (2013) Basic Res Cardiol , vol.108 , pp. 326
    • Lu, J.1    Bian, Z.Y.2    Zhang, R.3
  • 162
    • 0037470133 scopus 로고    scopus 로고
    • The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity
    • Gusterson RJ, Jazrawi E, Adcock IM, Latchman DS., The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity. J Biol Chem 2003;278:6838-6847. doi: 10.1074/jbc.M211762200
    • (2003) J Biol Chem , vol.278 , pp. 6838-6847
    • Gusterson, R.J.1    Jazrawi, E.2    Adcock, I.M.3    Latchman, D.S.4
  • 165
    • 67949112796 scopus 로고    scopus 로고
    • The IκB kinase β/nuclear factor κB signaling pathway protects the heart from hemodynamic stress mediated by the regulation of manganese superoxide dismutase expression
    • Hikoso S, Yamaguchi O, Nakano Y, The IκB kinase β/nuclear factor κB signaling pathway protects the heart from hemodynamic stress mediated by the regulation of manganese superoxide dismutase expression. Circ Res 2009;105:70-79. doi: 10.1161/CIRCRESAHA.108.193318
    • (2009) Circ Res , vol.105 , pp. 70-79
    • Hikoso, S.1    Yamaguchi, O.2    Nakano, Y.3
  • 166
    • 62249162170 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore and ischemia-reperfusion injury
    • Baines CP., The mitochondrial permeability transition pore and ischemia-reperfusion injury. Basic Res Cardiol 2009;104:181-188. doi: 10.1007/s00395-009-0004-8
    • (2009) Basic Res Cardiol , vol.104 , pp. 181-188
    • Baines, C.P.1
  • 167
    • 0034991316 scopus 로고    scopus 로고
    • Pathophysiology, clinical manifestations, and prevention of ischemia-reperfusion injury
    • Collard CD, Gelman S., Pathophysiology, clinical manifestations, and prevention of ischemia-reperfusion injury. Anesthesiology 2001;94:1133-1138.
    • (2001) Anesthesiology , vol.94 , pp. 1133-1138
    • Collard, C.D.1    Gelman, S.2
  • 169
    • 42049108814 scopus 로고    scopus 로고
    • Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury
    • Murphy E, Steenbergen C., Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury. Physiol Rev 2008;88:581-609. doi: 10.1152/physrev.00024.2007
    • (2008) Physiol Rev , vol.88 , pp. 581-609
    • Murphy, E.1    Steenbergen, C.2
  • 170
    • 0032487493 scopus 로고    scopus 로고
    • Changes in interferon-regulatory factor-1 mRNA levels after transient ischemia in rat brain
    • Paschen W, Gissel C, Althausen S, Doutheil J., Changes in interferon-regulatory factor-1 mRNA levels after transient ischemia in rat brain. Neuroreport 1998;9:3147-3151.
    • (1998) Neuroreport , vol.9 , pp. 3147-3151
    • Paschen, W.1    Gissel, C.2    Althausen, S.3    Doutheil, J.4
  • 171
    • 0033557359 scopus 로고    scopus 로고
    • The transcription factor interferon regulatory factor 1 is expressed after cerebral ischemia and contributes to ischemic brain injury
    • Iadecola C, Salkowski CA, Zhang F, Aber T, Nagayama M, Vogel SN, Ross ME., The transcription factor interferon regulatory factor 1 is expressed after cerebral ischemia and contributes to ischemic brain injury. J Exp Med 1999;189:719-727.
    • (1999) J Exp Med , vol.189 , pp. 719-727
    • Iadecola, C.1    Salkowski, C.A.2    Zhang, F.3    Aber, T.4    Nagayama, M.5    Vogel, S.N.6    Ross, M.E.7
  • 172
    • 84903166194 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cell-derived IFN-α promotes murine liver ischemia/reperfusion injury by induction of hepatocyte IRF-1
    • Castellaneta A, Yoshida O, Kimura S, Yokota S, Geller DA, Murase N, Thomson AW., Plasmacytoid dendritic cell-derived IFN-α promotes murine liver ischemia/reperfusion injury by induction of hepatocyte IRF-1. Hepatology 2014;60:267-277. doi: 10.1002/hep.27037
    • (2014) Hepatology , vol.60 , pp. 267-277
    • Castellaneta, A.1    Yoshida, O.2    Kimura, S.3    Yokota, S.4    Geller, D.A.5    Murase, N.6    Thomson, A.W.7
  • 173
    • 67650566633 scopus 로고    scopus 로고
    • Donor graft interferon regulatory factor-1 gene transfer worsens liver transplant ischemia/reperfusion injury
    • Kim KH, Dhupar R, Ueki S, Cardinal J, Pan P, Cao Z, Cho SW, Murase N, Tsung A, Geller DA., Donor graft interferon regulatory factor-1 gene transfer worsens liver transplant ischemia/reperfusion injury. Surgery 2009;146:181-189. doi: 10.1016/j.surg.2009.06.011
    • (2009) Surgery , vol.146 , pp. 181-189
    • Kim, K.H.1    Dhupar, R.2    Ueki, S.3    Cardinal, J.4    Pan, P.5    Cao, Z.6    Cho, S.W.7    Murase, N.8    Tsung, A.9    Geller, D.A.10
  • 176
    • 84880134559 scopus 로고    scopus 로고
    • Chloroquine pretreatment inhibits toll-like receptor 3 signaling after stroke
    • Cui G, Ye X, Zuo T, Zhao H, Zhao Q, Chen W, Hua F., Chloroquine pretreatment inhibits toll-like receptor 3 signaling after stroke. Neurosci Lett 2013;548:101-104. doi: 10.1016/j.neulet.2013.02.072
    • (2013) Neurosci Lett , vol.548 , pp. 101-104
    • Cui, G.1    Ye, X.2    Zuo, T.3    Zhao, H.4    Zhao, Q.5    Chen, W.6    Hua, F.7
  • 177
    • 79958248587 scopus 로고    scopus 로고
    • Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury
    • Stevens SL, Leung PY, Vartanian KB, Gopalan B, Yang T, Simon RP, Stenzel-Poore MP., Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury. J Neurosci 2011;31:8456-8463. doi: 10.1523/JNEUROSCI.0821-11.2011
    • (2011) J Neurosci , vol.31 , pp. 8456-8463
    • Stevens, S.L.1    Leung, P.Y.2    Vartanian, K.B.3    Gopalan, B.4    Yang, T.5    Simon, R.P.6    Stenzel-Poore, M.P.7
  • 178
    • 68549089184 scopus 로고    scopus 로고
    • Systemic lipopolysaccharide protects the brain from ischemic injury by reprogramming the response of the brain to stroke: A critical role for IRF3
    • Marsh B, Stevens SL, Packard AE, Gopalan B, Hunter B, Leung PY, Harrington CA, Stenzel-Poore MP., Systemic lipopolysaccharide protects the brain from ischemic injury by reprogramming the response of the brain to stroke: A critical role for IRF3. J Neurosci 2009;29:9839-9849. doi: 10.1523/JNEUROSCI.2496-09.2009
    • (2009) J Neurosci , vol.29 , pp. 9839-9849
    • Marsh, B.1    Stevens, S.L.2    Packard, A.E.3    Gopalan, B.4    Hunter, B.5    Leung, P.Y.6    Harrington, C.A.7    Stenzel-Poore, M.P.8
  • 180
    • 84906159752 scopus 로고    scopus 로고
    • Interferon regulatory factor 9 is an essential mediator of heart dysfunction and cell death following myocardial ischemia/reperfusion injury
    • Zhang Y, Liu X, She ZG, Jiang DS, Wan N, Xia H, Zhu XH, Wei X, Zhang XD, Li H., Interferon regulatory factor 9 is an essential mediator of heart dysfunction and cell death following myocardial ischemia/reperfusion injury. Basic Res Cardiol 2014;109:434. doi: 10.1007/s00395-014-0434-9
    • (2014) Basic Res Cardiol , vol.109 , pp. 434
    • Zhang, Y.1    Liu, X.2    She, Z.G.3    Jiang, D.S.4    Wan, N.5    Xia, H.6    Zhu, X.H.7    Wei, X.8    Zhang, X.D.9    Li, H.10
  • 181
    • 84906898008 scopus 로고    scopus 로고
    • A critical role for interferon regulatory factor 9 in cerebral ischemic stroke
    • Chen HZ, Guo S, Li ZZ, A critical role for interferon regulatory factor 9 in cerebral ischemic stroke. J Neurosci 2014;34:11897-11912. doi: 10.1523/JNEUROSCI.1545-14.2014
    • (2014) J Neurosci , vol.34 , pp. 11897-11912
    • Chen, H.Z.1    Guo, S.2    Li, Z.Z.3
  • 183
    • 27544434763 scopus 로고    scopus 로고
    • Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
    • Chen WY, Wang DH, Yen RC, Luo J, Gu W, Baylin SB., Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell 2005;123:437-448. doi: 10.1016/j.cell.2005.08.011
    • (2005) Cell , vol.123 , pp. 437-448
    • Chen, W.Y.1    Wang, D.H.2    Yen, R.C.3    Luo, J.4    Gu, W.5    Baylin, S.B.6
  • 184
    • 3142654210 scopus 로고    scopus 로고
    • Inferences, questions and possibilities in Toll-like receptor signalling
    • Beutler B., Inferences, questions and possibilities in Toll-like receptor signalling. Nature 2004;430:257-263. doi: 10.1038/nature02761
    • (2004) Nature , vol.430 , pp. 257-263
    • Beutler, B.1
  • 185
    • 47149105036 scopus 로고    scopus 로고
    • Toll-like receptors and adaptor molecules in liver disease: Update
    • Seki E, Brenner DA., Toll-like receptors and adaptor molecules in liver disease: Update. Hepatology 2008;48:322-335. doi: 10.1002/hep.22306
    • (2008) Hepatology , vol.48 , pp. 322-335
    • Seki, E.1    Brenner, D.A.2
  • 186
    • 78649696296 scopus 로고    scopus 로고
    • Endogenous toll-like receptor ligands and their biological significance
    • Yu L, Wang L, Chen S., Endogenous toll-like receptor ligands and their biological significance. J Cell Mol Med 2010;14:2592-2603. doi: 10.1111/j.1582-4934.2010.01127.x
    • (2010) J Cell Mol Med , vol.14 , pp. 2592-2603
    • Yu, L.1    Wang, L.2    Chen, S.3
  • 187
    • 68349143099 scopus 로고    scopus 로고
    • Toll-like receptors: Link between "danger" ligands and plaque instability
    • Balogh S, Kiss I, Csaszar A., Toll-like receptors: Link between "danger" ligands and plaque instability. Curr Drug Targets 2009;10:513-518.
    • (2009) Curr Drug Targets , vol.10 , pp. 513-518
    • Balogh, S.1    Kiss, I.2    Csaszar, A.3
  • 188
    • 84904730993 scopus 로고    scopus 로고
    • Understanding and modulating the Toll like Receptors (TLRs) and NOD like Receptors (NLRs) cross talk in type 2 diabetes
    • Prajapati B, Jena PK, Rajput P, Purandhar K, Seshadri S., Understanding and modulating the Toll like Receptors (TLRs) and NOD like Receptors (NLRs) cross talk in type 2 diabetes. Curr Diabetes Rev 2014;10:190-200.
    • (2014) Curr Diabetes Rev , vol.10 , pp. 190-200
    • Prajapati, B.1    Jena, P.K.2    Rajput, P.3    Purandhar, K.4    Seshadri, S.5
  • 189
    • 84902657591 scopus 로고    scopus 로고
    • Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease
    • Miura K, Ohnishi H., Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease. World J Gastroenterol 2014;20:7381-7391. doi: 10.3748/wjg.v20.i23.7381
    • (2014) World J Gastroenterol , vol.20 , pp. 7381-7391
    • Miura, K.1    Ohnishi, H.2
  • 190
    • 84855508991 scopus 로고    scopus 로고
    • Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice
    • Kim SJ, Choi Y, Choi YH, Park T., Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice. J Nutr Biochem 2012;23:113-122. doi: 10.1016/j.jnutbio.2010.10.012
    • (2012) J Nutr Biochem , vol.23 , pp. 113-122
    • Kim, S.J.1    Choi, Y.2    Choi, Y.H.3    Park, T.4
  • 191
    • 77955492173 scopus 로고    scopus 로고
    • Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
    • Ehses JA, Meier DT, Wueest S, Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet. Diabetologia 2010;53:1795-1806. doi: 10.1007/s00125-010-1747-3
    • (2010) Diabetologia , vol.53 , pp. 1795-1806
    • Ehses, J.A.1    Meier, D.T.2    Wueest, S.3
  • 192
    • 77952315676 scopus 로고    scopus 로고
    • Tlr2 is critical for diet-induced metabolic syndrome in a murine model
    • Himes RW, Smith CW., Tlr2 is critical for diet-induced metabolic syndrome in a murine model. FASEB J 2010;24:731-739. doi: 10.1096/fj.09-141929
    • (2010) FASEB J , vol.24 , pp. 731-739
    • Himes, R.W.1    Smith, C.W.2
  • 193
    • 79959267977 scopus 로고    scopus 로고
    • Toll-like receptors, inflammation, metabolism and obesity
    • Fresno M, Alvarez R, Cuesta N., Toll-like receptors, inflammation, metabolism and obesity. Arch Physiol Biochem 2011;117:151-164. doi: 10.3109/13813455.2011.562514
    • (2011) Arch Physiol Biochem , vol.117 , pp. 151-164
    • Fresno, M.1    Alvarez, R.2    Cuesta, N.3
  • 194
    • 34548272744 scopus 로고    scopus 로고
    • Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis
    • Rivera CA, Adegboyega P, van Rooijen N, Tagalicud A, Allman M, Wallace M., Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis. J Hepatol 2007;47:571-579. doi: 10.1016/j.jhep.2007.04.019
    • (2007) J Hepatol , vol.47 , pp. 571-579
    • Rivera, C.A.1    Adegboyega, P.2    Van Rooijen, N.3    Tagalicud, A.4    Allman, M.5    Wallace, M.6
  • 195
    • 33750584214 scopus 로고    scopus 로고
    • TLR4 links innate immunity and fatty acid-induced insulin resistance
    • Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS., TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 2006;116:3015-3025. doi: 10.1172/JCI28898
    • (2006) J Clin Invest , vol.116 , pp. 3015-3025
    • Shi, H.1    Kokoeva, M.V.2    Inouye, K.3    Tzameli, I.4    Yin, H.5    Flier, J.S.6
  • 197
    • 84875938855 scopus 로고    scopus 로고
    • DNA methylation impairs TLR9 induced Foxp3 expression by attenuating IRF-7 binding activity in fulminant type 1 diabetes
    • Wang Z, Zheng Y, Hou C, Yang L, Li X, Lin J, Huang G, Lu Q, Wang CY, Zhou Z., DNA methylation impairs TLR9 induced Foxp3 expression by attenuating IRF-7 binding activity in fulminant type 1 diabetes. J Autoimmun 2013;41:50-59. doi: 10.1016/j.jaut.2013.01.009
    • (2013) J Autoimmun , vol.41 , pp. 50-59
    • Wang, Z.1    Zheng, Y.2    Hou, C.3    Yang, L.4    Li, X.5    Lin, J.6    Huang, G.7    Lu, Q.8    Wang, C.Y.9    Zhou, Z.10
  • 198
    • 23744454577 scopus 로고    scopus 로고
    • TLR signalling and activation of IRFs: Revisiting old friends from the NF-κB pathway
    • Moynagh PN., TLR signalling and activation of IRFs: Revisiting old friends from the NF-κB pathway. Trends Immunol 2005;26:469-476. doi: 10.1016/j.it.2005.06.009
    • (2005) Trends Immunol , vol.26 , pp. 469-476
    • Moynagh, P.N.1
  • 199
    • 84863161186 scopus 로고    scopus 로고
    • Hepatic TRAF2 regulates glucose metabolism through enhancing glucagon responses
    • Chen Z, Sheng L, Shen H, Zhao Y, Wang S, Brink R, Rui L., Hepatic TRAF2 regulates glucose metabolism through enhancing glucagon responses. Diabetes 2012;61:566-573. doi: 10.2337/db11-0474
    • (2012) Diabetes , vol.61 , pp. 566-573
    • Chen, Z.1    Sheng, L.2    Shen, H.3    Zhao, Y.4    Wang, S.5    Brink, R.6    Rui, L.7
  • 200
    • 84937431765 scopus 로고    scopus 로고
    • Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity
    • Chen Z, Shen H, Sun C, Yin L, Tang F, Zheng P, Liu Y, Brink R, Rui L., Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity. Am J Physiol Endocrinol Metab 2015 308 E460 E469. doi: 10.1152/ajpendo.00470.2014
    • (2015) Am J Physiol Endocrinol Metab , vol.308 , pp. E460-E469
    • Chen, Z.1    Shen, H.2    Sun, C.3    Yin, L.4    Tang, F.5    Zheng, P.6    Liu, Y.7    Brink, R.8    Rui, L.9
  • 202
    • 32644464262 scopus 로고    scopus 로고
    • IRF family proteins and type I interferon induction in dendritic cells
    • Tailor P, Tamura T, Ozato K., IRF family proteins and type I interferon induction in dendritic cells. Cell Res 2006;16:134-140. doi: 10.1038/sj.cr.7310018
    • (2006) Cell Res , vol.16 , pp. 134-140
    • Tailor, P.1    Tamura, T.2    Ozato, K.3
  • 204
    • 84898828288 scopus 로고    scopus 로고
    • Mindin/Spondin 2 inhibits hepatic steatosis, insulin resistance, and obesity via interaction with peroxisome proliferator-activated receptor α in mice
    • Zhu LH, Wang A, Luo P, Wang X, Jiang DS, Deng W, Zhang X, Wang T, Liu Y, Gao L, Zhang S, Zhang X, Zhang J, Li H., Mindin/Spondin 2 inhibits hepatic steatosis, insulin resistance, and obesity via interaction with peroxisome proliferator-activated receptor α in mice. J Hepatol 2014;60:1046-1054. doi: 10.1016/j.jhep.2014.01.011
    • (2014) J Hepatol , vol.60 , pp. 1046-1054
    • Zhu, L.H.1    Wang, A.2    Luo, P.3    Wang, X.4    Jiang, D.S.5    Deng, W.6    Zhang, X.7    Wang, T.8    Liu, Y.9    Gao, L.10    Zhang, S.11    Zhang, X.12    Zhang, J.13    Li, H.14
  • 205
    • 79955129532 scopus 로고    scopus 로고
    • Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands
    • Magalhaes JG, Lee J, Geddes K, Rubino S, Philpott DJ, Girardin SE., Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands. Eur J Immunol 2011;41:1445-1455. doi: 10.1002/eji.201040827
    • (2011) Eur J Immunol , vol.41 , pp. 1445-1455
    • Magalhaes, J.G.1    Lee, J.2    Geddes, K.3    Rubino, S.4    Philpott, D.J.5    Girardin, S.E.6
  • 207
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson GK., Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005;352:1685-1695. doi: 10.1056/NEJMra043430
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 210
    • 8444252436 scopus 로고    scopus 로고
    • TLR signaling: An emerging bridge from innate immunity to atherogenesis
    • Michelsen KS, Doherty TM, Shah PK, Arditi M., TLR signaling: An emerging bridge from innate immunity to atherogenesis. J Immunol 2004;173:5901-5907.
    • (2004) J Immunol , vol.173 , pp. 5901-5907
    • Michelsen, K.S.1    Doherty, T.M.2    Shah, P.K.3    Arditi, M.4
  • 211
    • 84866148207 scopus 로고    scopus 로고
    • Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists
    • Curtiss LK, Black AS, Bonnet DJ, Tobias PS., Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists. J Lipid Res 2012;53:2126-2132. doi: 10.1194/jlr.M028431
    • (2012) J Lipid Res , vol.53 , pp. 2126-2132
    • Curtiss, L.K.1    Black, A.S.2    Bonnet, D.J.3    Tobias, P.S.4
  • 212
    • 77950020916 scopus 로고    scopus 로고
    • Toll like receptor 4 in atherosclerosis and plaque destabilization
    • den Dekker WK, Cheng C, Pasterkamp G, Duckers HJ., Toll like receptor 4 in atherosclerosis and plaque destabilization. Atherosclerosis 2010;209:314-320. doi: 10.1016/j.atherosclerosis.2009.09.075
    • (2010) Atherosclerosis , vol.209 , pp. 314-320
    • Den Dekker, W.K.1    Cheng, C.2    Pasterkamp, G.3    Duckers, H.J.4
  • 214
    • 84865263402 scopus 로고    scopus 로고
    • Toll-like receptor 7 protects from atherosclerosis by constraining "inflammatory" macrophage activation
    • Salagianni M, Galani IE, Lundberg AM, Toll-like receptor 7 protects from atherosclerosis by constraining "inflammatory" macrophage activation. Circulation 2012;126:952-962. doi: 10.1161/CIRCULATIONAHA.111.067678
    • (2012) Circulation , vol.126 , pp. 952-962
    • Salagianni, M.1    Galani, I.E.2    Lundberg, A.M.3
  • 217
    • 0035179082 scopus 로고    scopus 로고
    • Upregulation of TRAF-3 by shear stress blocks CD40-mediated endothelial activation
    • Urbich C, Mallat Z, Tedgui A, Clauss M, Zeiher AM, Dimmeler S., Upregulation of TRAF-3 by shear stress blocks CD40-mediated endothelial activation. J Clin Invest 2001;108:1451-1458. doi: 10.1172/JCI13620
    • (2001) J Clin Invest , vol.108 , pp. 1451-1458
    • Urbich, C.1    Mallat, Z.2    Tedgui, A.3    Clauss, M.4    Zeiher, A.M.5    Dimmeler, S.6
  • 218
    • 34648814152 scopus 로고    scopus 로고
    • A20 attenuates vascular smooth muscle cell proliferation and migration through blocking PI3k/Akt singling in vitro and in vivo
    • Wang AB, Li HL, Zhang R, She ZG, Chen HZ, Huang Y, Liu DP, Liang CC., A20 attenuates vascular smooth muscle cell proliferation and migration through blocking PI3k/Akt singling in vitro and in vivo. J Biomed Sci 2007;14:357-371. doi: 10.1007/s11373-007-9150-x
    • (2007) J Biomed Sci , vol.14 , pp. 357-371
    • Wang, A.B.1    Li, H.L.2    Zhang, R.3    She, Z.G.4    Chen, H.Z.5    Huang, Y.6    Liu, D.P.7    Liang, C.C.8
  • 219
    • 0042818084 scopus 로고    scopus 로고
    • A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis
    • Longo CR, Arvelo MB, Patel VI, Daniel S, Mahiou J, Grey ST, Ferran C., A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis. Circulation 2003;108:1113-1118. doi: 10.1161/01.CIR.0000083718.76889.D0
    • (2003) Circulation , vol.108 , pp. 1113-1118
    • Longo, C.R.1    Arvelo, M.B.2    Patel, V.I.3    Daniel, S.4    Mahiou, J.5    Grey, S.T.6    Ferran, C.7
  • 220
    • 36749057932 scopus 로고    scopus 로고
    • The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-κB target genes
    • Wolfrum S, Teupser D, Tan M, Chen KY, Breslow JL., The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-κB target genes. Proc Natl Acad Sci U S A 2007;104:18601-18606. doi: 10.1073/pnas.0709011104
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 18601-18606
    • Wolfrum, S.1    Teupser, D.2    Tan, M.3    Chen, K.Y.4    Breslow, J.L.5
  • 221
    • 33745599620 scopus 로고    scopus 로고
    • A20 inhibits oxidized low-density lipoprotein-induced apoptosis through negative Fas/Fas ligand-dependent activation of caspase-8 and mitochondrial pathways in murine RAW264.7 macrophages
    • Li HL, Wang AB, Zhang R, Wei YS, Chen HZ, She ZG, Huang Y, Liu DP, Liang CC., A20 inhibits oxidized low-density lipoprotein-induced apoptosis through negative Fas/Fas ligand-dependent activation of caspase-8 and mitochondrial pathways in murine RAW264.7 macrophages. J Cell Physiol 2006;208:307-318. doi: 10.1002/jcp.20665
    • (2006) J Cell Physiol , vol.208 , pp. 307-318
    • Li, H.L.1    Wang, A.B.2    Zhang, R.3    Wei, Y.S.4    Chen, H.Z.5    She, Z.G.6    Huang, Y.7    Liu, D.P.8    Liang, C.C.9
  • 222
    • 84910072274 scopus 로고    scopus 로고
    • A20 regulates atherogenic interferon (IFN)-γ signaling in vascular cells by modulating basal IFNβ levels
    • Moll HP, Lee A, Minussi DC, da Silva CG, Csizmadia E, Bhasin M, Ferran C., A20 regulates atherogenic interferon (IFN)-γ signaling in vascular cells by modulating basal IFNβ levels. J Biol Chem 2014;289:30912-30924. doi: 10.1074/jbc.M114.591966
    • (2014) J Biol Chem , vol.289 , pp. 30912-30924
    • Moll, H.P.1    Lee, A.2    Minussi, D.C.3    Da Silva, C.G.4    Csizmadia, E.5    Bhasin, M.6    Ferran, C.7
  • 226
    • 79955832940 scopus 로고    scopus 로고
    • Toll-like receptors as potential therapeutic targets in cardiac dysfunction
    • Hofmann U, Ertl G, Frantz S., Toll-like receptors as potential therapeutic targets in cardiac dysfunction. Expert Opin Ther Targets 2011;15:753-765. doi: 10.1517/14728222.2011.566560
    • (2011) Expert Opin Ther Targets , vol.15 , pp. 753-765
    • Hofmann, U.1    Ertl, G.2    Frantz, S.3
  • 229
    • 84904003624 scopus 로고    scopus 로고
    • Central blockade of TLR4 improves cardiac function and attenuates myocardial inflammation in angiotensin II-induced hypertension
    • Dange RB, Agarwal D, Masson GS, Vila J, Wilson B, Nair A, Francis J., Central blockade of TLR4 improves cardiac function and attenuates myocardial inflammation in angiotensin II-induced hypertension. Cardiovasc Res 2014;103:17-27. doi: 10.1093/cvr/cvu067
    • (2014) Cardiovasc Res , vol.103 , pp. 17-27
    • Dange, R.B.1    Agarwal, D.2    Masson, G.S.3    Vila, J.4    Wilson, B.5    Nair, A.6    Francis, J.7
  • 230
    • 34547941623 scopus 로고    scopus 로고
    • Association between toll-like receptor 8 expression and adverse clinical outcomes in patients with enterovirus-associated dilated cardiomyopathy
    • Satoh M, Akatsu T, Ishikawa Y, Minami Y, Takahashi Y, Nakamura M., Association between toll-like receptor 8 expression and adverse clinical outcomes in patients with enterovirus-associated dilated cardiomyopathy. Am Heart J 2007;154:581-588. doi: 10.1016/j.ahj.2007.05.010
    • (2007) Am Heart J , vol.154 , pp. 581-588
    • Satoh, M.1    Akatsu, T.2    Ishikawa, Y.3    Minami, Y.4    Takahashi, Y.5    Nakamura, M.6
  • 231
    • 68949145035 scopus 로고    scopus 로고
    • Cutting edge: Cardiac myosin activates innate immune responses through TLRs
    • Zhang P, Cox CJ, Alvarez KM, Cunningham MW., Cutting edge: Cardiac myosin activates innate immune responses through TLRs. J Immunol 2009;183:27-31. doi: 10.4049/jimmunol.0800861
    • (2009) J Immunol , vol.183 , pp. 27-31
    • Zhang, P.1    Cox, C.J.2    Alvarez, K.M.3    Cunningham, M.W.4
  • 232
    • 84898059190 scopus 로고    scopus 로고
    • Double-stranded RNA-dependent protein kinase deficiency protects the heart from systolic overload-induced congestive heart failure
    • Wang H, Xu X, Fassett J, Kwak D, Liu X, Hu X, Falls TJ, Bell JC, Li H, Bitterman P, Bache RJ, Chen Y., Double-stranded RNA-dependent protein kinase deficiency protects the heart from systolic overload-induced congestive heart failure. Circulation 2014;129:1397-1406. doi: 10.1161/CIRCULATIONAHA.113.002209
    • (2014) Circulation , vol.129 , pp. 1397-1406
    • Wang, H.1    Xu, X.2    Fassett, J.3    Kwak, D.4    Liu, X.5    Hu, X.6    Falls, T.J.7    Bell, J.C.8    Li, H.9    Bitterman, P.10    Bache, R.J.11    Chen, Y.12
  • 233
    • 0042519617 scopus 로고    scopus 로고
    • A20 is dynamically regulated in the heart and inhibits the hypertrophic response
    • Cook SA, Novikov MS, Ahn Y, Matsui T, Rosenzweig A., A20 is dynamically regulated in the heart and inhibits the hypertrophic response. Circulation 2003;108:664-667. doi: 10.1161/01.CIR.0000086978.95976.41
    • (2003) Circulation , vol.108 , pp. 664-667
    • Cook, S.A.1    Novikov, M.S.2    Ahn, Y.3    Matsui, T.4    Rosenzweig, A.5
  • 234
    • 77955504366 scopus 로고    scopus 로고
    • Tumor suppressor A20 protects against cardiac hypertrophy and fibrosis by blocking transforming growth factor-beta-activated kinase 1-dependent signaling
    • Huang H, Tang QZ, Wang AB, Chen M, Yan L, Liu C, Jiang H, Yang Q, Bian ZY, Bai X, Zhu LH, Wang L, Li H., Tumor suppressor A20 protects against cardiac hypertrophy and fibrosis by blocking transforming growth factor-beta-activated kinase 1-dependent signaling. Hypertension 2010;56:232-239. doi: 10.1161/HYPERTENSIONAHA.110.149963
    • (2010) Hypertension , vol.56 , pp. 232-239
    • Huang, H.1    Tang, Q.Z.2    Wang, A.B.3    Chen, M.4    Yan, L.5    Liu, C.6    Jiang, H.7    Yang, Q.8    Bian, Z.Y.9    Bai, X.10    Zhu, L.H.11    Wang, L.12    Li, H.13
  • 235
    • 34247106590 scopus 로고    scopus 로고
    • Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction
    • Li HL, Zhuo ML, Wang D, Wang AB, Cai H, Sun LH, Yang Q, Huang Y, Wei YS, Liu PP, Liu DP, Liang CC., Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction. Circulation 2007;115:1885-1894. doi: 10.1161/CIRCULATIONAHA.106.656835
    • (2007) Circulation , vol.115 , pp. 1885-1894
    • Li, H.L.1    Zhuo, M.L.2    Wang, D.3    Wang, A.B.4    Cai, H.5    Sun, L.H.6    Yang, Q.7    Huang, Y.8    Wei, Y.S.9    Liu, P.P.10    Liu, D.P.11    Liang, C.C.12
  • 236
    • 77951194340 scopus 로고    scopus 로고
    • Human T cell lymphotropic virus 1 manipulates interferon regulatory signals by controlling the TAK1-IRF3 and IRF4 pathways
    • Suzuki S, Zhou Y, Refaat A, Takasaki I, Koizumi K, Yamaoka S, Tabuchi Y, Saiki I, Sakurai H., Human T cell lymphotropic virus 1 manipulates interferon regulatory signals by controlling the TAK1-IRF3 and IRF4 pathways. J Biol Chem 2010;285:4441-4446. doi: 10.1074/jbc.M109.031476
    • (2010) J Biol Chem , vol.285 , pp. 4441-4446
    • Suzuki, S.1    Zhou, Y.2    Refaat, A.3    Takasaki, I.4    Koizumi, K.5    Yamaoka, S.6    Tabuchi, Y.7    Saiki, I.8    Sakurai, H.9
  • 237
    • 0037177171 scopus 로고    scopus 로고
    • New concepts in diastolic dysfunction and diastolic heart failure: Part II: Causal mechanisms and treatment
    • Zile MR, Brutsaert DL., New concepts in diastolic dysfunction and diastolic heart failure: Part II: Causal mechanisms and treatment. Circulation 2002;105:1503-1508.
    • (2002) Circulation , vol.105 , pp. 1503-1508
    • Zile, M.R.1    Brutsaert, D.L.2
  • 238
    • 80052877375 scopus 로고    scopus 로고
    • Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1-Smad signalling
    • Yan L, Wei X, Tang QZ, Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1-Smad signalling. Cardiovasc Res 2011;92:85-94. doi: 10.1093/cvr/cvr159
    • (2011) Cardiovasc Res , vol.92 , pp. 85-94
    • Yan, L.1    Wei, X.2    Tang, Q.Z.3
  • 239
    • 84865143490 scopus 로고    scopus 로고
    • Disruption of mindin exacerbates cardiac hypertrophy and fibrosis
    • Bian ZY, Wei X, Deng S, Disruption of mindin exacerbates cardiac hypertrophy and fibrosis. J Mol Med (Berl) 2012;90:895-910. doi: 10.1007/s00109-012-0883-2
    • (2012) J Mol Med (Berl) , vol.90 , pp. 895-910
    • Bian, Z.Y.1    Wei, X.2    Deng, S.3
  • 240
    • 0036510366 scopus 로고    scopus 로고
    • Negative regulation of toll-like receptor-mediated signaling by Tollip
    • Zhang G, Ghosh S., Negative regulation of toll-like receptor-mediated signaling by Tollip. J Biol Chem 2002;277:7059-7065. doi: 10.1074/jbc.M109537200
    • (2002) J Biol Chem , vol.277 , pp. 7059-7065
    • Zhang, G.1    Ghosh, S.2
  • 243
    • 33746596242 scopus 로고    scopus 로고
    • CARD tricks: Controlling the interactions of CARD6 with RICK and microtubules
    • Dufner A, Mak TW., CARD tricks: Controlling the interactions of CARD6 with RICK and microtubules. Cell Cycle 2006;5:797-800.
    • (2006) Cell Cycle , vol.5 , pp. 797-800
    • Dufner, A.1    Mak, T.W.2
  • 245
    • 1242336786 scopus 로고    scopus 로고
    • Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice
    • Oyama J, Blais C Jr, Liu X, Pu M, Kobzik L, Kelly RA, Bourcier T., Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice. Circulation 2004;109:784-789. doi: 10.1161/01.CIR.0000112575.66565.84
    • (2004) Circulation , vol.109 , pp. 784-789
    • Oyama, J.1    Blais, C.2    Liu, X.3    Pu, M.4    Kobzik, L.5    Kelly, R.A.6    Bourcier, T.7
  • 249
    • 80053974958 scopus 로고    scopus 로고
    • LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury
    • Vartanian KB, Stevens SL, Marsh BJ, Williams-Karnesky R, Lessov NS, Stenzel-Poore MP., LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury. J Neuroinflammation 2011;8:140. doi: 10.1186/1742-2094-8-140
    • (2011) J Neuroinflammation , vol.8 , pp. 140
    • Vartanian, K.B.1    Stevens, S.L.2    Marsh, B.J.3    Williams-Karnesky, R.4    Lessov, N.S.5    Stenzel-Poore, M.P.6
  • 250
    • 47549085328 scopus 로고    scopus 로고
    • Preconditioning with a TLR2 specific ligand increases resistance to cerebral ischemia/reperfusion injury
    • Hua F, Ma J, Ha T, Kelley J, Williams DL, Kao RL, Kalbfleisch JH, Browder IW, Li C., Preconditioning with a TLR2 specific ligand increases resistance to cerebral ischemia/reperfusion injury. J Neuroimmunol 2008;199:75-82. doi: 10.1016/j.jneuroim.2008.05.009
    • (2008) J Neuroimmunol , vol.199 , pp. 75-82
    • Hua, F.1    Ma, J.2    Ha, T.3    Kelley, J.4    Williams, D.L.5    Kao, R.L.6    Kalbfleisch, J.H.7    Browder, I.W.8    Li, C.9
  • 253
    • 77957858212 scopus 로고    scopus 로고
    • Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia
    • Hyakkoku K, Hamanaka J, Tsuruma K, Shimazawa M, Tanaka H, Uematsu S, Akira S, Inagaki N, Nagai H, Hara H., Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia. Neuroscience 2010;171:258-267. doi: 10.1016/j.neuroscience.2010.08.054
    • (2010) Neuroscience , vol.171 , pp. 258-267
    • Hyakkoku, K.1    Hamanaka, J.2    Tsuruma, K.3    Shimazawa, M.4    Tanaka, H.5    Uematsu, S.6    Akira, S.7    Inagaki, N.8    Nagai, H.9    Hara, H.10
  • 254
    • 70350551801 scopus 로고    scopus 로고
    • Toll-like receptor 4 is a key mediator of murine steatotic liver warm ischemia/reperfusion injury
    • Ellett JD, Evans ZP, Atkinson C, Schmidt MG, Schnellmann RG, Chavin KD., Toll-like receptor 4 is a key mediator of murine steatotic liver warm ischemia/reperfusion injury. Liver Transpl 2009;15:1101-1109. doi: 10.1002/lt.21782
    • (2009) Liver Transpl , vol.15 , pp. 1101-1109
    • Ellett, J.D.1    Evans, Z.P.2    Atkinson, C.3    Schmidt, M.G.4    Schnellmann, R.G.5    Chavin, K.D.6
  • 257
    • 80051999172 scopus 로고    scopus 로고
    • Toll-like receptor 4 knockout mice are protected from endothelial overactivation in the absence of Kupffer cells after total hepatic ischemia/reperfusion
    • Ellett JD, Atkinson C, Evans ZP, Amani Z, Balish E, Schmidt MG, Schnellmann RG, Chavin KD., Toll-like receptor 4 knockout mice are protected from endothelial overactivation in the absence of Kupffer cells after total hepatic ischemia/reperfusion. Liver Transpl 2011;17:1089-1098. doi: 10.1002/lt.22333
    • (2011) Liver Transpl , vol.17 , pp. 1089-1098
    • Ellett, J.D.1    Atkinson, C.2    Evans, Z.P.3    Amani, Z.4    Balish, E.5    Schmidt, M.G.6    Schnellmann, R.G.7    Chavin, K.D.8
  • 258
    • 23244459411 scopus 로고    scopus 로고
    • TLR2 mRNA upregulation in ischemic lobes in mouse partial hepatic ischemia/reperfusion injury model
    • Zhang J, Wu H, Wang L, Zhang J, Wang H, Zheng Q., TLR2 mRNA upregulation in ischemic lobes in mouse partial hepatic ischemia/reperfusion injury model. J Huazhong Univ Sci Technolog Med Sci 2004;24:144-146.
    • (2004) J Huazhong Univ Sci Technolog Med Sci , vol.24 , pp. 144-146
    • Zhang, J.1    Wu, H.2    Wang, L.3    Zhang, J.4    Wang, H.5    Zheng, Q.6
  • 259
    • 23244454596 scopus 로고    scopus 로고
    • Protection against hepatic ischemia/reperfusion injury via downregulation of toll-like receptor 2 expression by inhibition of Kupffer cell function
    • Zhang JX, Wu HS, Wang H, Zhang JH, Wang Y, Zheng QC., Protection against hepatic ischemia/reperfusion injury via downregulation of toll-like receptor 2 expression by inhibition of Kupffer cell function. World J Gastroenterol 2005;11:4423-4426.
    • (2005) World J Gastroenterol , vol.11 , pp. 4423-4426
    • Zhang, J.X.1    Wu, H.S.2    Wang, H.3    Zhang, J.H.4    Wang, Y.5    Zheng, Q.C.6
  • 260
    • 75449096565 scopus 로고    scopus 로고
    • Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury
    • Bamboat ZM, Balachandran VP, Ocuin LM, Obaid H, Plitas G, DeMatteo RP., Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury. Hepatology 2010;51:621-632. doi: 10.1002/hep.23365
    • (2010) Hepatology , vol.51 , pp. 621-632
    • Bamboat, Z.M.1    Balachandran, V.P.2    Ocuin, L.M.3    Obaid, H.4    Plitas, G.5    DeMatteo, R.P.6
  • 263
    • 77749291737 scopus 로고    scopus 로고
    • Innate immunity mediates myocardial preconditioning through Toll-like receptor 2 and TIRAP-dependent signaling pathways
    • Dong JW, Vallejo JG, Tzeng HP, Thomas JA, Mann DL., Innate immunity mediates myocardial preconditioning through Toll-like receptor 2 and TIRAP-dependent signaling pathways. Am J Physiol Heart Circ Physiol 2010 298 H1079 H1087. doi: 10.1152/ajpheart.00306.2009
    • (2010) Am J Physiol Heart Circ Physiol , vol.298 , pp. H1079-H1087
    • Dong, J.W.1    Vallejo, J.G.2    Tzeng, H.P.3    Thomas, J.A.4    Mann, D.L.5
  • 265
    • 84914707849 scopus 로고    scopus 로고
    • Activation of liver X receptor improves viability of adipose-derived mesenchymal stem cells to attenuate myocardial ischemia injury through TLR4/NF-κB and Keap-1/Nrf-2 signaling pathways
    • Wang Y, Li C, Cheng K, Zhang R, Narsinh K, Li S, Li X, Qin X, Zhang R, Li C, Su T, Chen J, Cao F., Activation of liver X receptor improves viability of adipose-derived mesenchymal stem cells to attenuate myocardial ischemia injury through TLR4/NF-κB and Keap-1/Nrf-2 signaling pathways. Antioxid Redox Signal 2014;21:2543-2557. doi: 10.1089/ars.2013.5683
    • (2014) Antioxid Redox Signal , vol.21 , pp. 2543-2557
    • Wang, Y.1    Li, C.2    Cheng, K.3    Zhang, R.4    Narsinh, K.5    Li, S.6    Li, X.7    Qin, X.8    Zhang, R.9    Li, C.10    Su, T.11    Chen, J.12    Cao, F.13
  • 266
    • 58149500135 scopus 로고    scopus 로고
    • Toll-like receptor signaling: A critical modulator of cell survival and ischemic injury in the heart
    • Chao W., Toll-like receptor signaling: A critical modulator of cell survival and ischemic injury in the heart. Am J Physiol Heart Circ Physiol 2009 296 H1 12. doi: 10.1152/ajpheart.00995.2008
    • (2009) Am J Physiol Heart Circ Physiol , vol.296 , pp. H1-12
    • Chao, W.1
  • 267
    • 79952175742 scopus 로고    scopus 로고
    • Interferon regulatory factor 1 mediates acetylation and release of high mobility group box 1 from hepatocytes during murine liver ischemia-reperfusion injury
    • Dhupar R, Klune JR, Evankovich J, Cardinal J, Zhang M, Ross M, Murase N, Geller DA, Billiar TR, Tsung A., Interferon regulatory factor 1 mediates acetylation and release of high mobility group box 1 from hepatocytes during murine liver ischemia-reperfusion injury. Shock 2011;35:293-301. doi: 10.1097/SHK.0b013e3181f6aab0
    • (2011) Shock , vol.35 , pp. 293-301
    • Dhupar, R.1    Klune, J.R.2    Evankovich, J.3    Cardinal, J.4    Zhang, M.5    Ross, M.6    Murase, N.7    Geller, D.A.8    Billiar, T.R.9    Tsung, A.10
  • 270
    • 84880569986 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor-associated factor 5 is an essential mediator of ischemic brain infarction
    • Wang L, Lu Y, Guan H, Jiang D, Guan Y, Zhang X, Nakano H, Zhou Y, Zhang Y, Yang L, Li H., Tumor necrosis factor receptor-associated factor 5 is an essential mediator of ischemic brain infarction. J Neurochem 2013;126:400-414. doi: 10.1111/jnc.12207
    • (2013) J Neurochem , vol.126 , pp. 400-414
    • Wang, L.1    Lu, Y.2    Guan, H.3    Jiang, D.4    Guan, Y.5    Zhang, X.6    Nakano, H.7    Zhou, Y.8    Zhang, Y.9    Yang, L.10    Li, H.11
  • 271
    • 84870723813 scopus 로고    scopus 로고
    • A20 is up-regulated in primary mouse hepatocytes subjected to hypoxia and reperfusion
    • Sun J, Sun L, Zhang N, Lu X, Zhang H., A20 is up-regulated in primary mouse hepatocytes subjected to hypoxia and reperfusion. Cell Biochem Funct 2012;30:683-686. doi: 10.1002/cbf.2850
    • (2012) Cell Biochem Funct , vol.30 , pp. 683-686
    • Sun, J.1    Sun, L.2    Zhang, N.3    Lu, X.4    Zhang, H.5
  • 273
    • 32544434769 scopus 로고    scopus 로고
    • Neuroprotective effect of A20 on TNF-induced postischemic apoptosis
    • Yu L, Miao H, Hou Y, Zhang B, Guo L., Neuroprotective effect of A20 on TNF-induced postischemic apoptosis. Neurochem Res 2006;31:21-32. doi: 10.1007/s11064-005-9004-8
    • (2006) Neurochem Res , vol.31 , pp. 21-32
    • Yu, L.1    Miao, H.2    Hou, Y.3    Zhang, B.4    Guo, L.5
  • 274
    • 79960448766 scopus 로고    scopus 로고
    • Aggravation of post-ischemic liver injury by overexpression of A20, an NF-κB suppressor
    • Yu J, Lee HS, Lee SM, Yu HC, Moon WS, Chung MJ, Park JW, Park BH., Aggravation of post-ischemic liver injury by overexpression of A20, an NF-κB suppressor. J Hepatol 2011;55:328-336. doi: 10.1016/j.jhep.2010.11.029
    • (2011) J Hepatol , vol.55 , pp. 328-336
    • Yu, J.1    Lee, H.S.2    Lee, S.M.3    Yu, H.C.4    Moon, W.S.5    Chung, M.J.6    Park, J.W.7    Park, B.H.8
  • 275
    • 84937425943 scopus 로고    scopus 로고
    • Toll-interacting protein contributes to mortality following myocardial infarction through promoting inflammation and apoptosis
    • Wan N, Liu X, Zhang XJ, Zhao Y, Hu G, Wan F, Zhang R, Zhu X, Xia H, Li H., Toll-interacting protein contributes to mortality following myocardial infarction through promoting inflammation and apoptosis. Br J Pharmacol 2015. doi: 10.1111/bph.13130
    • (2015) Br J Pharmacol
    • Wan, N.1    Liu, X.2    Zhang, X.J.3    Zhao, Y.4    Hu, G.5    Wan, F.6    Zhang, R.7    Zhu, X.8    Xia, H.9    Li, H.10
  • 276
    • 73349101856 scopus 로고    scopus 로고
    • Dynamic evolution of immune system regulators: The history of the interferon regulatory factor family
    • Nehyba J, Hrdlicková R, Bose HR., Dynamic evolution of immune system regulators: The history of the interferon regulatory factor family. Mol Biol Evol 2009;26:2539-2550. doi: 10.1093/molbev/msp167
    • (2009) Mol Biol Evol , vol.26 , pp. 2539-2550
    • Nehyba, J.1    Hrdlicková, R.2    Bose, H.R.3
  • 277
    • 84879254416 scopus 로고    scopus 로고
    • Lineage-specific expansion of IFIT gene family: An insight into coevolution with IFN gene family
    • Liu Y, Zhang YB, Liu TK, Gui JF., Lineage-specific expansion of IFIT gene family: An insight into coevolution with IFN gene family. PLoS One 2013 8 e66859. doi: 10.1371/journal.pone.0066859
    • (2013) PLoS One , vol.8 , pp. e66859
    • Liu, Y.1    Zhang, Y.B.2    Liu, T.K.3    Gui, J.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.