IRF family proteins and type I interferon induction in dendritic cells

Cell Research

Volumn 16, Issue 2, 2006, Pages 134-140

  Tailor, Prafullakumar ^a   Tamura, Tomohiko ^a   Ozato, Keiko ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Activate transcription; Dendritic cells; IRF 3, 4, 5, 7, 8; Signaling pathway dependence; Type I interferon induction

Indexed keywords

INTERFERON; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR 4; INTERFERON REGULATORY FACTOR-4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

ANIMAL; CONFERENCE PAPER; DENDRITIC CELL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; TRANSCRIPTION INITIATION;

ANIMALS; DENDRITIC CELLS; GENE EXPRESSION REGULATION; INTERFERON REGULATORY FACTORS; INTERFERON TYPE I; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 9; TRANSCRIPTIONAL ACTIVATION;

EID: 32644464262     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/sj.cr.7310018     Document Type: Conference Paper

References (60)

1. Carbone FR, Heath WR. The role of dendritic cell subsets in immunity to viruses. Curr Opin Immunol 2003; 15:416-20.
2. Edwards AD, Chaussabel D, Tomlinson S, et al. Relationships among murine CD11c(high) dendritic cell subsets as revealed by baseline gene expression patterns. J Immunol 2003; 171:47-60.
3. Manz MG, Traver D, Miyamoto T, et al. Dendritic cell potentials of early lymphoid and myeloid progenitors. Blood 2001; 97:3333-41.
4. Tamura T, Ozato K. ICSBP/IRF-8: its regulatory roles in the development of myeloid cells. J Interferon Cytokine Res 2002; 22:145-52.
5. Levi BZ, Hashmueli S, Gleit-Kielmanowicz M, et al. ICSBP/TRF-8 transactivation: a tale of protein-protein interaction. J Interferon Cytokine Res 2002; 22:153-60.
6. Tamura T, Tailor P, Yamaoka K, et al. IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity. J Immunol 2005; 174:2573-81.
7. Tsujimura H, Tamura T, Gongora C, et al. ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro. Blood 2003; 101:961-9.
8. Schiavoni G, Mattei F, Sestili P, et al. ICSBP Is Essential for the Development of Mouse Type I Interferon-producing Cells and for the Generation and Activation of CD8 {alpha}+ Dendritic Cells. J Exp Med 2002; 196:1415-25.
9. + dendritic cells. Blood 2003; 101:305-10.
10. Suzuki S, Honma K, Matsuyama T, et al. Critical roles of interferon regulatory factor 4 in CD11bhighCD8alpha- dendritic cell development. Proc Natl Acad Sci U S A 2004; 101:8981-6.
11. Tsujimura H, Tamura T, Ozato K. Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells. J Immunol 2003; 170:1131-5.
12. Gilliet M, Boonstra A, Paturel C, et al. The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor. J Exp Med 2002; 195:953-8.
13. Laouar Y, Welte T, Fu XY, Flavell RA. STAT3 is required for Flt3L-dependent dendritic cell differentiation. Immunity 2003; 19:903-12.
14. Lehtonen A, Veckman V, Nikula T, et al. Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages. J Immunol 2005; 175:6570-9.
15. Grumont RJ, Gerondakis S. Rel induces interferon regulatory factor 4 (IRF-4) expression in lymphocytes: modulation of interferon-regulated gene expression by rel/nuclear factor kappaB. J Exp Med 2000; 191:1281-92.
16. Wu L, D'Amico A, Winkel KD, et al. RelB is essential for the development of myeloid-related CD8alpha- dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells. Immunity 1998; 9:839-47.
17. Honda K, Mizutani T, Taniguchi T. Negative regulation of IFN-alpha/beta signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells. Proc Natl Acad Sci U S A 2004; 101:2416-21.
18. Ichikawa E, Hida S, Omatsu Y, et al. Defective development of splenic and epidermal CD4+ dendritic cells in mice deficient for IFN regulatory factor-2. Proc Natl Acad Sci U S A 2004; 101:3909-14.
19. Taki S, Sato T, Ogasawara K, et al. Multistage Regulation of Th1-Type Immune Responses by the Transcription Factor IRF-1. Immunity 1997; 6:673-9.
20. Lohoff M, Ferrick D, Mittrucker H-W, et al. Interferon Regulatory Factor-1 Is Required for a T Helper 1 Immune Response In Vivo. Immunity 1997; 6:681-9.
21. Takaoka A, Yanai H, Kondo S, et al. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 2005; 434:243-9.
22. Negishi H, Ohba Y, Yanai H, et al. Negative regulation of Toll-like-receptor signaling by IRF-4. Proc Natl Acad Sci U S A 2005; 102:15989-94.
23. Tsujimura H, Tamura T, Kong HJ, et al. Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells. J Immunol 2004; 172:6820-27.
24. Luft T, Pang KC, Thomas E, et al. Type I FFNs enhance the terminal differentiation of dendritic cells. J Immunol 1998; 161:1947-53.
25. Santini SM, Di Pucchio T, Lapenta C, et al. A New Type I IFN-Mediated Pathway for the Rapid Differentiation of Monocytes into Highly Active Dendritic Cells. Stem Cells 2003; 21:357-62.
26. Banchereau J, Pascual V, Palucka AK. Autoimmunity through cytokine-induced dendritic cell activation. Immunity 2004; 20:539-50.
27. O'Keeffe M, Hochrein H, Vremec D, et al. Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulus. J Exp Med 2002; 196:1307-9.
28. Asselin-Paturel C, Trinchieri G. Production of type I interferons: plasmacytoid dendritic cells and beyond. J Exp Med 2005; 202:461-5.
29. Wakkach A, Fournier N, Brun V, et al. Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 2003; 18:605-7.
30. Cao X-T. cytokines required for the generation and function of regulatory dendritic cells. Cell Research 2005; 15:61.
31. Corinti S, Albanesi C, la Sala A, et al. Regulatory Activity of Autocrine IL-10 on Dendritic Cell Functions. J Immunol 2001; 166:4312-8.
32. Dalod M, Salazar-Mather TP, Malmgaard L, et al. Interferon α/β and Interleukin 12 Responses to Viral Infections: Pathways Regulating Dendritic Cell Cytokine Expression In Vivo. J Exp Med 2002; 195:517-8.
33. Biron CA. Interferons alpha and beta as immune regulators-a new look. Immunity 2001; 14:661-4.
34. Marie I, Durbin JE, Levy DE. Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7. EMBO J 1998; 17:6660-9.
35. Fitzgerald KA, McWhirter SM, Faia KL, et al. IKKε and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol 2003; 4:491-6.
36. Sharma S, tenOever BR, Grandvaux N, et al. Triggering the Interferon Antiviral Response Through an IKK-Related Pathway. Science 2003; 300:1148-51.
37. Agalioti T, Lomvardas S, Parekh B, et al. Ordered Recruitment of Chromatin Modifying and General Transcription Factors to the IFN-β Promoter. Cell 2000; 103:667-78.
38. Erlandsson L, Blumenthal R, Eloranta M-L, et al. Interferon-β is required for interferon-aα production in mouse fibroblasts. Current Biology 1998; 8:223-6.
39. Honda K, Yanai H, Negishi H, et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 2005; 434:772-7.
40. Munshi N, Agalioti T, Lomvardas S, et al. Coordination of a Transcriptional Switch by HMGI(Y) Acetylation. Science 2001; 293:1133-6.
41. Sato M, Suemori H, Hata N, et al. Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction. Immunity 2000; 13:539-48.
42. Lin R, Genin P, Mamane Y, Hiscott J. Selective DNA Binding and Association with the CREB Binding Protein Coactivator Contribute to Differential Activation of Alpha/Beta Interferon Genes by Interferon Regulatory Factors 3 and 7. Mol Cell Biol 2000; 20:6342-53.
43. Civas A, Island ML, Genin P, et al. Regulation of virus-induced interferon-A genes. Biochimie 2002; 84:643-54.
44. Dai J, Megjugorac NJ, Amrute SB, Fitzgerald-Bocarsly P. Regulation of IFN regulatory factor-7 and IFN-alpha production by enveloped virus and lipopolysaccharide in human plasmacytoid dendritic cells. J Immunol 2004; 173:1535-48.
45. Gautier G, Humbert M, Deauvieau F, et al. A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J Exp Med 2005; 201:1435-46.
46. Kawai T, Sato S, Ishii KJ, et al. Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat Immunol 2004; 5:1061-8.
47. Honda K, Ohba Y, Yanai H, et al. Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction. Nature 2005; 434:1035-40.
48. Diebold SS, Montoya M, Unger H, et al. Viral infection switches non-plasmacytoid dendritic cells into high interferon producers. Nature 2003; 424:324-28.
49. Kato H, Sato S, Yoneyama M, et al. Cell type-specific involvement of RIG-I in antiviral response. Immunity 2005; 23:19-28.
50. Yoneyama M, Kikuchi M, Natsukawa T, et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004; 5:730-7.
51. Kang DC, Gopalkrishnan RV, Wu Q, et al. mda-5 : An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties. Proc Natl Acad Sci U S A 2002; 99:637-42.
52. Yoneyama M, Kikuchi M, Matsumoto K, et al. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 2005; 175:2851-8.
53. Kawai T, Takahashi K, Sato S, et al. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol 2005; 6:981-8.
54. Seth RB, Sun L, Ea CK, Chen ZJ. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 2005; 122:669-82.
55. Xu LG, Wang YY, Han KJ, et al. VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling. Molecular Cell 2005; 19:727-40.
56. Meylan E, Curran J, Hofmann K, et al. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 2005; 437:1167-72.
57. Balachandran S, Thomas E, Barber GN. A FADD-dependent innate immune mechanism in mammalian cells. Nature 2004; 432:401-5.
58. Meylan E, Burns K, Hofmann K, et al. RTP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. Nat Immunol 2004; 5:503-7.
59. Saitoh T, Yamamoto M, Miyagishi M, et al. A20 is a negative regulator of IFN regulatory factor 3 signaling. J Immunol 2005; 174:1507-12.
60. Nardi V, Mohammad A, Dikovskaia E, Daley GQ. Interferons and IRF8/ICSBP Stimulate Immune Protection Against BCR/ABL-Induced Leukemia. Blood (ASH Annual Meeting Abstracts) 2004; 104:2965.