-
1
-
-
13844292408
-
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
-
Sigurdsson S, Nordmark G, Goring HH, Lindroos K, Wiman AC, et al. (2005) Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet 76: 528-537.
-
(2005)
Am J Hum Genet
, vol.76
, pp. 528-537
-
-
Sigurdsson, S.1
Nordmark, G.2
Goring, H.H.3
Lindroos, K.4
Wiman, A.C.5
-
2
-
-
33646368404
-
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
-
Graham RR, Kozyrev SV, Baechler EC, Reddy MV, Plenge RM, et al. (2006) A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nat Genet 38: 550-555.
-
(2006)
Nat Genet
, vol.38
, pp. 550-555
-
-
Graham, R.R.1
Kozyrev, S.V.2
Baechler, E.C.3
Reddy, M.V.4
Plenge, R.M.5
-
3
-
-
34249860408
-
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
-
Graham RR, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, et al. (2007) Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci U S A 104: 6758-6763.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 6758-6763
-
-
Graham, R.R.1
Kyogoku, C.2
Sigurdsson, S.3
Vlasova, I.A.4
Davies, L.R.5
-
4
-
-
34547541897
-
Opposed independent effects and epistasis in the complex association of IRF5 to SLE
-
Ferreiro-Neira I, Calaza M, Alonso-Perez E, Marchini M, Scorza R, et al. (2007) Opposed independent effects and epistasis in the complex association of IRF5 to SLE. Genes Immun 8: 429-438.
-
(2007)
Genes Immun
, vol.8
, pp. 429-438
-
-
Ferreiro-Neira, I.1
Calaza, M.2
Alonso-Perez, E.3
Marchini, M.4
Scorza, R.5
-
5
-
-
42549152933
-
Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans
-
Kelly JA, Kelley JM, Kaufman KM, Kilpatrick J, Bruner GR, et al. (2008) Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans. Genes Immun 9: 187-194.
-
(2008)
Genes Immun
, vol.9
, pp. 187-194
-
-
Kelly, J.A.1
Kelley, J.M.2
Kaufman, K.M.3
Kilpatrick, J.4
Bruner, G.R.5
-
6
-
-
79953718368
-
Interferon regulatory factor 5 is critical for the development of lupus in MRL/lpr mice
-
Tada Y, Kondo S, Aoki S, Koarada S, Inoue H, et al. (2011) Interferon regulatory factor 5 is critical for the development of lupus in MRL/lpr mice. Arthritis Rheum 63: 738-748.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 738-748
-
-
Tada, Y.1
Kondo, S.2
Aoki, S.3
Koarada, S.4
Inoue, H.5
-
7
-
-
76249125968
-
IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosus
-
Richez C, Yasuda K, Bonegio RG, Watkins AA, Aprahamian T, et al. (2010) IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosus. Journal of Immunology 184: 796-806.
-
(2010)
Journal of Immunology
, vol.184
, pp. 796-806
-
-
Richez, C.1
Yasuda, K.2
Bonegio, R.G.3
Watkins, A.A.4
Aprahamian, T.5
-
8
-
-
77949518633
-
Critical role of IRF-5 in regulation of B-cell differentiation
-
Lien C, Fang CM, Huso D, Livak F, Lu R, et al. (2010) Critical role of IRF-5 in regulation of B-cell differentiation. Proc Natl Acad Sci U S A 107: 4664-4668.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4664-4668
-
-
Lien, C.1
Fang, C.M.2
Huso, D.3
Livak, F.4
Lu, R.5
-
9
-
-
77953368347
-
Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus
-
Savitsky DA, Yanai H, Tamura T, Taniguchi T, Honda K, (2010) Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus. Proc Natl Acad Sci U S A 107: 10154-10159.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 10154-10159
-
-
Savitsky, D.A.1
Yanai, H.2
Tamura, T.3
Taniguchi, T.4
Honda, K.5
-
10
-
-
15044345461
-
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
-
Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, et al. (2005) Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 434: 243-249.
-
(2005)
Nature
, vol.434
, pp. 243-249
-
-
Takaoka, A.1
Yanai, H.2
Kondo, S.3
Duncan, G.4
Negishi, H.5
-
11
-
-
20444368020
-
Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function
-
Mancl ME, Hu G, Sangster-Guity N, Olshalsky SL, Hoops K, et al. (2005) Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function. J Biol Chem 280: 21078-21090.
-
(2005)
J Biol Chem
, vol.280
, pp. 21078-21090
-
-
Mancl, M.E.1
Hu, G.2
Sangster-Guity, N.3
Olshalsky, S.L.4
Hoops, K.5
-
12
-
-
0037171938
-
Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53
-
Mori T, Anazawa Y, Iiizumi M, Fukuda S, Nakamura Y, et al. (2002) Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53. Oncogene 21: 2914-2918.
-
(2002)
Oncogene
, vol.21
, pp. 2914-2918
-
-
Mori, T.1
Anazawa, Y.2
Iiizumi, M.3
Fukuda, S.4
Nakamura, Y.5
-
13
-
-
5644280149
-
Modulation of gene expression in human central nervous system tumors under methionine deprivation-induced stress
-
Kokkinakis DM, Liu X, Chada S, Ahmed MM, Shareef MM, et al. (2004) Modulation of gene expression in human central nervous system tumors under methionine deprivation-induced stress. Cancer Res 64: 7513-7525.
-
(2004)
Cancer Res
, vol.64
, pp. 7513-7525
-
-
Kokkinakis, D.M.1
Liu, X.2
Chada, S.3
Ahmed, M.M.4
Shareef, M.M.5
-
14
-
-
33744906762
-
Differential activation of IFN regulatory factor (IRF)-3 and IRF-5 transcription factors during viral infection
-
Cheng TF, Brzostek S, Ando O, Van Scoy S, Kumar KP, et al. (2006) Differential activation of IFN regulatory factor (IRF)-3 and IRF-5 transcription factors during viral infection. J Immunol 176: 7462-7470.
-
(2006)
J Immunol
, vol.176
, pp. 7462-7470
-
-
Cheng, T.F.1
Brzostek, S.2
Ando, O.3
van Scoy, S.4
Kumar, K.P.5
-
15
-
-
13244281709
-
A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization
-
Lin RT, Yang L, Arguello M, Penafuerte C, Hiscott J, (2005) A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization. Journal of Biological Chemistry 280: 3088-3095.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 3088-3095
-
-
Lin, R.T.1
Yang, L.2
Arguello, M.3
Penafuerte, C.4
Hiscott, J.5
-
16
-
-
57349121051
-
Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination
-
Balkhi MY, Fitzgerald KA, Pitha PM, (2008) Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination. Mol Cell Biol 28: 7296-7308.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 7296-7308
-
-
Balkhi, M.Y.1
Fitzgerald, K.A.2
Pitha, P.M.3
-
17
-
-
20444380445
-
The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling
-
Schoenemeyer A, Barnes BJ, Mancl ME, Latz E, Goutagny N, et al. (2005) The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling. Journal of Biological Chemistry 280: 17005-17012.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 17005-17012
-
-
Schoenemeyer, A.1
Barnes, B.J.2
Mancl, M.E.3
Latz, E.4
Goutagny, N.5
-
18
-
-
0035968246
-
Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes
-
Barnes BJ, Moore PA, Pitha PM, (2001) Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes. Journal of Biological Chemistry 276: 23382-23390.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 23382-23390
-
-
Barnes, B.J.1
Moore, P.A.2
Pitha, P.M.3
-
19
-
-
33947506493
-
Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation
-
Lamothe B, Besse A, Campos AD, Webster WK, Wu H, et al. (2007) Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation. J Biol Chem 282: 4102-4112.
-
(2007)
J Biol Chem
, vol.282
, pp. 4102-4112
-
-
Lamothe, B.1
Besse, A.2
Campos, A.D.3
Webster, W.K.4
Wu, H.5
-
20
-
-
69549116880
-
The E3 ligase TRAF6 regulates Akt ubiquitination and activation
-
Yang WL, Wang J, Chan CH, Lee SW, Campos AD, et al. (2009) The E3 ligase TRAF6 regulates Akt ubiquitination and activation. Science 325: 1134-1138.
-
(2009)
Science
, vol.325
, pp. 1134-1138
-
-
Yang, W.L.1
Wang, J.2
Chan, C.H.3
Lee, S.W.4
Campos, A.D.5
-
21
-
-
37548999003
-
NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2
-
Yang Y, Yin C, Pandey A, Abbott D, Sassetti C, et al. (2007) NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2. J Biol Chem 282: 36223-36229.
-
(2007)
J Biol Chem
, vol.282
, pp. 36223-36229
-
-
Yang, Y.1
Yin, C.2
Pandey, A.3
Abbott, D.4
Sassetti, C.5
-
22
-
-
0242720415
-
TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology
-
Wu H, Arron JR, (2003) TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology. Bioessays 25: 1096-1105.
-
(2003)
Bioessays
, vol.25
, pp. 1096-1105
-
-
Wu, H.1
Arron, J.R.2
-
23
-
-
38549084725
-
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation
-
Hasegawa M, Fujimoto Y, Lucas PC, Nakano H, Fukase K, et al. (2008) A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation. EMBO J 27: 373-383.
-
(2008)
EMBO J
, vol.27
, pp. 373-383
-
-
Hasegawa, M.1
Fujimoto, Y.2
Lucas, P.C.3
Nakano, H.4
Fukase, K.5
-
24
-
-
33846936219
-
RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs
-
Park JH, Kim YG, McDonald C, Kanneganti TD, Hasegawa M, et al. (2007) RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs. J Immunol 178: 2380-2386.
-
(2007)
J Immunol
, vol.178
, pp. 2380-2386
-
-
Park, J.H.1
Kim, Y.G.2
McDonald, C.3
Kanneganti, T.D.4
Hasegawa, M.5
-
25
-
-
0037075551
-
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
-
Kobayashi K, Inohara N, Hernandez LD, Galan JE, Nunez G, et al. (2002) RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 416: 194-199.
-
(2002)
Nature
, vol.416
, pp. 194-199
-
-
Kobayashi, K.1
Inohara, N.2
Hernandez, L.D.3
Galan, J.E.4
Nunez, G.5
-
26
-
-
0037075549
-
Involvement of receptor-interacting protein 2 in innate and adaptive immune responses
-
Chin AI, Dempsey PW, Bruhn K, Miller JF, Xu Y, et al. (2002) Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature 416: 190-194.
-
(2002)
Nature
, vol.416
, pp. 190-194
-
-
Chin, A.I.1
Dempsey, P.W.2
Bruhn, K.3
Miller, J.F.4
Xu, Y.5
-
27
-
-
40449136493
-
The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals
-
Hitotsumatsu O, Ahmad RC, Tavares R, Wang M, Philpott D, et al. (2008) The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals. Immunity 28: 381-390.
-
(2008)
Immunity
, vol.28
, pp. 381-390
-
-
Hitotsumatsu, O.1
Ahmad, R.C.2
Tavares, R.3
Wang, M.4
Philpott, D.5
-
28
-
-
0036311933
-
Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes
-
Barnes BJ, Kellum MJ, Field AE, Pitha PM, (2002) Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes. Molecular and Cellular Biology 22: 5721-5740.
-
(2002)
Molecular and Cellular Biology
, vol.22
, pp. 5721-5740
-
-
Barnes, B.J.1
Kellum, M.J.2
Field, A.E.3
Pitha, P.M.4
-
29
-
-
0141919557
-
Interferon regulatory factor 5, a novel mediator of cell cycle arrest and cell death
-
Barnes BJ, Kellum MJ, Pinder KE, Frisancho JA, Pitha PM, (2003) Interferon regulatory factor 5, a novel mediator of cell cycle arrest and cell death. Cancer Research 63: 6424-6431.
-
(2003)
Cancer Research
, vol.63
, pp. 6424-6431
-
-
Barnes, B.J.1
Kellum, M.J.2
Pinder, K.E.3
Frisancho, J.A.4
Pitha, P.M.5
-
30
-
-
70049094025
-
NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis
-
Pandey AK, Yang Y, Jiang Z, Fortune SM, Coulombe F, et al. (2009) NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis. PLoS Pathog 5: e1000500.
-
(2009)
PLoS Pathog
, vol.5
-
-
Pandey, A.K.1
Yang, Y.2
Jiang, Z.3
Fortune, S.M.4
Coulombe, F.5
-
31
-
-
82955249021
-
NOD-like receptors and the innate immune system: coping with danger, damage and death
-
Kersse K, Bertrand MJ, Lamkanfi M, Vandenabeele P, (2011) NOD-like receptors and the innate immune system: coping with danger, damage and death. Cytokine Growth Factor Rev 22: 257-276.
-
(2011)
Cytokine Growth Factor Rev
, vol.22
, pp. 257-276
-
-
Kersse, K.1
Bertrand, M.J.2
Lamkanfi, M.3
Vandenabeele, P.4
-
32
-
-
80052174103
-
Peptidoglycan: a critical activator of the mammalian immune system during infection and homeostasis
-
Sorbara MT, Philpott DJ, (2011) Peptidoglycan: a critical activator of the mammalian immune system during infection and homeostasis. Immunol Rev 243: 40-60.
-
(2011)
Immunol Rev
, vol.243
, pp. 40-60
-
-
Sorbara, M.T.1
Philpott, D.J.2
-
33
-
-
66149086936
-
NOD-like receptors: role in innate immunity and inflammatory disease
-
Chen G, Shaw MH, Kim YG, Nunez G, (2009) NOD-like receptors: role in innate immunity and inflammatory disease. Annu Rev Pathol 4: 365-398.
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 365-398
-
-
Chen, G.1
Shaw, M.H.2
Kim, Y.G.3
Nunez, G.4
-
34
-
-
0032146749
-
Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1
-
Kudo N, Wolff B, Sekimoto T, Schreiner EP, Yoneda Y, et al. (1998) Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1. Exp Cell Res 242: 540-547.
-
(1998)
Exp Cell Res
, vol.242
, pp. 540-547
-
-
Kudo, N.1
Wolff, B.2
Sekimoto, T.3
Schreiner, E.P.4
Yoneda, Y.5
-
35
-
-
8844237615
-
Polyubiquitin chains: polymeric protein signals
-
Pickart CM, Fushman D, (2004) Polyubiquitin chains: polymeric protein signals. Curr Opin Chem Biol 8: 610-616.
-
(2004)
Curr Opin Chem Biol
, vol.8
, pp. 610-616
-
-
Pickart, C.M.1
Fushman, D.2
-
36
-
-
77952716624
-
The A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7
-
Ning S, Pagano JS, (2010) The A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7. J Virol 84: 6130-6138.
-
(2010)
J Virol
, vol.84
, pp. 6130-6138
-
-
Ning, S.1
Pagano, J.S.2
-
37
-
-
38149051652
-
Structure of the A20 OTU domain and mechanistic insights into deubiquitination
-
Komander D, Barford D, (2008) Structure of the A20 OTU domain and mechanistic insights into deubiquitination. Biochem J 409: 77-85.
-
(2008)
Biochem J
, vol.409
, pp. 77-85
-
-
Komander, D.1
Barford, D.2
-
38
-
-
78650915537
-
Deubiquitinases in the regulation of NF-kappaB signaling
-
Harhaj EW, Dixit VM, (2011) Deubiquitinases in the regulation of NF-kappaB signaling. Cell Res 21: 22-39.
-
(2011)
Cell Res
, vol.21
, pp. 22-39
-
-
Harhaj, E.W.1
Dixit, V.M.2
-
39
-
-
68149170034
-
ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways
-
Tao M, Scacheri PC, Marinis JM, Harhaj EW, Matesic LE, et al. (2009) ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways. Curr Biol 19: 1255-1263.
-
(2009)
Curr Biol
, vol.19
, pp. 1255-1263
-
-
Tao, M.1
Scacheri, P.C.2
Marinis, J.M.3
Harhaj, E.W.4
Matesic, L.E.5
-
40
-
-
23844463088
-
Signaling through IFN regulatory factor-5 sensitizes p53-deficient tumors to DNA damage-induced apoptosis and cell death
-
Hu G, Mancl ME, Barnes BJ, (2005) Signaling through IFN regulatory factor-5 sensitizes p53-deficient tumors to DNA damage-induced apoptosis and cell death. Cancer Res 65: 7403-7412.
-
(2005)
Cancer Res
, vol.65
, pp. 7403-7412
-
-
Hu, G.1
Mancl, M.E.2
Barnes, B.J.3
-
41
-
-
59149091466
-
IRF-5 is a mediator of the death receptor-induced apoptotic signaling pathway
-
Hu G, Barnes BJ, (2009) IRF-5 is a mediator of the death receptor-induced apoptotic signaling pathway. J Biol Chem 284: 2767-2777.
-
(2009)
J Biol Chem
, vol.284
, pp. 2767-2777
-
-
Hu, G.1
Barnes, B.J.2
-
42
-
-
79953143186
-
The interferon stimulated gene 54 promotes apoptosis
-
Stawowczyk M, Van Scoy S, Kumar KP, Reich NC, (2011) The interferon stimulated gene 54 promotes apoptosis. J Biol Chem 286: 7257-7266.
-
(2011)
J Biol Chem
, vol.286
, pp. 7257-7266
-
-
Stawowczyk, M.1
van Scoy, S.2
Kumar, K.P.3
Reich, N.C.4
-
43
-
-
34548656855
-
Signaling pathways downstream of pattern-recognition receptors and their cross talk
-
Lee MS, Kim YJ, (2007) Signaling pathways downstream of pattern-recognition receptors and their cross talk. Annu Rev Biochem 76: 447-480.
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 447-480
-
-
Lee, M.S.1
Kim, Y.J.2
-
44
-
-
42649114059
-
The IRF family transcription factors in immunity and oncogenesis
-
Tamura T, Yanai H, Savitsky D, Taniguchi T, (2008) The IRF family transcription factors in immunity and oncogenesis. Annu Rev Immunol 26: 535-584.
-
(2008)
Annu Rev Immunol
, vol.26
, pp. 535-584
-
-
Tamura, T.1
Yanai, H.2
Savitsky, D.3
Taniguchi, T.4
-
45
-
-
78649903914
-
Role for interferon regulatory factors in autoimmunity
-
Richez C, Barnetche T, Miceli-Richard C, Blanco P, Moreau JF, et al. (2010) Role for interferon regulatory factors in autoimmunity. Joint Bone Spine 77: 525-531.
-
(2010)
Joint Bone Spine
, vol.77
, pp. 525-531
-
-
Richez, C.1
Barnetche, T.2
Miceli-Richard, C.3
Blanco, P.4
Moreau, J.F.5
-
46
-
-
0038363463
-
Triggering the interferon antiviral response through an IKK-related pathway
-
Sharma S, tenOever BR, Grandvaux N, Zhou GP, Lin RT, et al. (2003) Triggering the interferon antiviral response through an IKK-related pathway. Science 300: 1148-1151.
-
(2003)
Science
, vol.300
, pp. 1148-1151
-
-
Sharma, S.1
tenOever, B.R.2
Grandvaux, N.3
Zhou, G.P.4
Lin, R.T.5
-
47
-
-
0038393016
-
IKK epsilon and TBK1 are essential components of the IRF3 signaling pathway
-
Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, et al. (2003) IKK epsilon and TBK1 are essential components of the IRF3 signaling pathway. Nature Immunology 4: 491-496.
-
(2003)
Nature Immunology
, vol.4
, pp. 491-496
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
-
48
-
-
0032915860
-
Structural and functional analysis of interferon regulatory factor 3: Localization of the transactivation and autoinhibitory domains
-
Lin RT, Mamane Y, Hiscott J, (1999) Structural and functional analysis of interferon regulatory factor 3: Localization of the transactivation and autoinhibitory domains. Molecular and Cellular Biology 19: 2465-2474.
-
(1999)
Molecular and Cellular Biology
, vol.19
, pp. 2465-2474
-
-
Lin, R.T.1
Mamane, Y.2
Hiscott, J.3
-
49
-
-
1642297150
-
Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation
-
Mori M, Yoneyama M, Ito T, Takahashi K, Inagaki F, et al. (2004) Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation. Journal of Biological Chemistry 279: 9698-9702.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 9698-9702
-
-
Mori, M.1
Yoneyama, M.2
Ito, T.3
Takahashi, K.4
Inagaki, F.5
-
50
-
-
34547930163
-
Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch
-
Panne D, McWhirter SM, Maniatis T, Harrison SC, (2007) Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch. J Biol Chem 282: 22816-22822.
-
(2007)
J Biol Chem
, vol.282
, pp. 22816-22822
-
-
Panne, D.1
McWhirter, S.M.2
Maniatis, T.3
Harrison, S.C.4
-
51
-
-
34548225910
-
Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains
-
Abbott DW, Yang Y, Hutti JE, Madhavarapu S, Kelliher MA, et al. (2007) Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains. Mol Cell Biol 27: 6012-6025.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6012-6025
-
-
Abbott, D.W.1
Yang, Y.2
Hutti, J.E.3
Madhavarapu, S.4
Kelliher, M.A.5
-
52
-
-
79955129532
-
Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands
-
Magalhaes JG, Lee J, Geddes K, Rubino S, Philpott DJ, et al. (2011) Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands. Eur J Immunol 41: 1445-1455.
-
(2011)
Eur J Immunol
, vol.41
, pp. 1445-1455
-
-
Magalhaes, J.G.1
Lee, J.2
Geddes, K.3
Rubino, S.4
Philpott, D.J.5
-
53
-
-
55549138004
-
Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5
-
Chen W, Lam SS, Srinath H, Jiang Z, Correia JJ, et al. (2008) Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5. Nat Struct Mol Biol 15: 1213-1220.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1213-1220
-
-
Chen, W.1
Lam, S.S.2
Srinath, H.3
Jiang, Z.4
Correia, J.J.5
-
54
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
-
Wertz IE, O'Rourke KM, Zhou H, Eby M, Aravind L, et al. (2004) De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature 430: 694-699.
-
(2004)
Nature
, vol.430
, pp. 694-699
-
-
Wertz, I.E.1
O'Rourke, K.M.2
Zhou, H.3
Eby, M.4
Aravind, L.5
-
55
-
-
33644850482
-
Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20
-
Lin R, Yang L, Nakhaei P, Sun Q, Sharif-Askari E, et al. (2006) Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20. J Biol Chem 281: 2095-2103.
-
(2006)
J Biol Chem
, vol.281
, pp. 2095-2103
-
-
Lin, R.1
Yang, L.2
Nakhaei, P.3
Sun, Q.4
Sharif-Askari, E.5
-
56
-
-
4944251748
-
A20 is a potent inhibitor of TLR3-and Sendai virus-induced activation of NF-kappa B and ISRE and IFN-beta promoter
-
Wang YY, Li LY, Han KJ, Zhai ZH, Shu HB, (2004) A20 is a potent inhibitor of TLR3-and Sendai virus-induced activation of NF-kappa B and ISRE and IFN-beta promoter. Febs Letters 576: 86-90.
-
(2004)
Febs Letters
, vol.576
, pp. 86-90
-
-
Wang, Y.Y.1
Li, L.Y.2
Han, K.J.3
Zhai, Z.H.4
Shu, H.B.5
-
57
-
-
0034602156
-
Multiple regulatory domains control IRF-7 activity in response to virus infection
-
Lin RT, Mamane Y, Hiscott J, (2000) Multiple regulatory domains control IRF-7 activity in response to virus infection. Journal of Biological Chemistry 275: 34320-34327.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 34320-34327
-
-
Lin, R.T.1
Mamane, Y.2
Hiscott, J.3
-
58
-
-
33744539146
-
IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways
-
Zhao J, Kong HJ, Li H, Huang B, Yang M, et al. (2006) IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. J Biol Chem 281: 10073-10080.
-
(2006)
J Biol Chem
, vol.281
, pp. 10073-10080
-
-
Zhao, J.1
Kong, H.J.2
Li, H.3
Huang, B.4
Yang, M.5
-
59
-
-
33344475413
-
Differential modification of Ras proteins by ubiquitination
-
Jura N, Scotto-Lavino E, Sobczyk A, Bar-Sagi D, (2006) Differential modification of Ras proteins by ubiquitination. Mol Cell 21: 679-687.
-
(2006)
Mol Cell
, vol.21
, pp. 679-687
-
-
Jura, N.1
Scotto-Lavino, E.2
Sobczyk, A.3
Bar-Sagi, D.4
|