IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high-fat meal

Circulation Research

Volumn 111, Issue 8, 2012, Pages 1054-1064

  Sun, Chongxiu ^a   Alkhoury, Kenan ^a   Wang, Ying I ^a   Foster, Greg A ^a   Radecke, Christopher E ^a   Tam, Kayan ^a   Edwards, Christina M ^a   Facciotti, Marc T ^a   Armstrong, Ehrin J ^b   Knowlton, Anne A ^c   Newman, John W ^c,d   Passerini, Anthony G ^a   Simon, Scott I ^a  

^a University of California   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

atherosclerosis; endothelial dysfunction; fatty acids; hypertriglyceridemia; triglycerides

Indexed keywords

APOLIPOPROTEIN C3; APOLIPOPROTEIN E; CHOLESTEROL; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERFERON REGULATORY FACTOR 1; LIPOPROTEIN; MICRORNA 126; OMEGA 3 FATTY ACID; TRANSCRIPTION FACTOR AP 1; TRIACYLGLYCEROL; TRIGLYCERIDE RICH LIPOPROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

AORTA; ARTICLE; ATHEROGENESIS; CELL ADHESION; CHEMICAL COMPOSITION; DENSITY; ENDOTHELIUM CELL; FAT INTAKE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; TRANSCRIPTION REGULATION; UPREGULATION;

AORTA; ATHEROSCLEROSIS; CELL ADHESION; CELL LINE; DIETARY FATS; DIETARY FATS, UNSATURATED; ENDOTHELIAL CELLS; HUMANS; HYPERTRIGLYCERIDEMIA; INTERFERON REGULATORY FACTOR-1; MICRORNAS; MONOCYTES; NF-KAPPA B; POSTPRANDIAL PERIOD; PROTEIN PROCESSING, POST-TRANSLATIONAL; TRANSCRIPTION FACTOR AP-1; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84867026573     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.270314     Document Type: Article

References (40)

1. Karpe F. Postprandial lipoprotein metabolism and atherosclerosis. J Intern Med. 1999;246:341-355. (Pubitemid 29479916)
2. Miller M, Stone NJ, Ballantyne C, Bittner V, Criqui MH, Ginsberg HN, Goldberg AC, Howard WJ, Jacobson MS, Kris-Etherton PM, Lennie TA, Levi M, Mazzone T, Pennathur S. Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association. Circulation. 2011;123:2292-2333.
3. Vogel RA, Corretti MC, Plotnick GD. Effect of a single high-fat meal on endothelial function in healthy subjects. Am J Cardiol. 1997;79:350-354. (Pubitemid 27093313)
4. Despres JP, Lemieux I, Bergeron J, Pibarot P, Mathieu P, Larose E, Rodes-Cabau J, Bertrand OF, Poirier P. Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk. Arterioscler Thromb Vasc Biol. 2008;28:1039-1049.
5. Chan JW, Motton D, Rutledge JC, Keim NL, Huser T. Raman spectroscopic analysis of biochemical changes in individual triglyceride-rich lipoproteins in the pre-and postprandial state. Analytic Chem. 2005;77:5870-5876. (Pubitemid 41324285)
6. Jackson KG, Wolstencroft EJ, Bateman PA, Yaqoob P, Williams CM. Greater enrichment of triacylglycerol-rich lipoproteins with apolipoproteins e and c-iii after meals rich in saturated fatty acids than after meals rich in unsaturated fatty acids. Am J Clin Nutr. 2005;81:25-34. (Pubitemid 43073372)
7. Williams CM, Maitin V, Jackson KG. Triacylglycerol-rich lipoprotein-gene interactions in endothelial cells. Biochem Soc Trans. 2004;32:994-998. (Pubitemid 39655525)
8. Wang L, Gill R, Pedersen TL, Higgins LJ, Newman JW, Rutledge JC. Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation. J Lipid Res. 2009;50:204-213.
9. Kawakami A, Aikawa M, Alcaide P, Luscinskas FW, Libby P, Sacks FM. Apolipoprotein CIII induces expression of vascular cell adhesion molecule-1 in vascular endothelial cells and increases adhesion of monocytic cells. Circulation. 2006;114:681-687. (Pubitemid 44252310)
10. Ley K, Laudanna C, Cybulsky MI, Nourshargh S. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol. 2007;7:678-689. (Pubitemid 47327397)
11. Ting HJ, Stice JP, Schaff UY, Hui DY, Rutledge JC, Knowlton AA, Passerini AG, Simon SI. Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha. Circ Res. 2007;100:381-390.
12. Wang YI, Schulze J, Raymond N, Tomita T, Tam K, Simon SI, Passerini AG. Endothelial inflammation correlates with subject triglycerides and waist size after a high-fat meal. Am J Physiol Heart Circ Physiol. 2011;300:H784-H791.
13. Gower RM, Wu H, Foster GA, Devaraj S, Jialal I, Ballantyne CM, Knowlton AA, Simon SI. Cd11c/cd18 expression is upregulated on blood monocytes during hypertriglyceridemia and enhances adhesion to vascular cell adhesion molecule-1. Arterioscler Thromb Vasc Biol. 2011;31:160-166.
14. Dagia NM, Harii N, Meli AE, Sun X, Lewis CJ, Kohn LD, Goetz DJ. Phenyl methimazole inhibits TNF-alpha-induced VCAM-1 expression in an IFN regulatory factor-1-dependent manner and reduces monocytic cell adhesion to endothelial cells. J Immunol. 2004;173:2041-2049. (Pubitemid 38971641)
15. Grapov D, Newman JW. Imdev: a graphical user interface to r multivariate analysis tools in Microsoft Excel. Bioinformatics. July 18, 2012. doi:10.1093/bioinformatics/bts439.; http://bioinformatics.oxfordjournals.org/ content/early/2012/07/18/bioinformatics.bts439.abstract. Accessed August 21, 2012.
16. Libby P. Inflammation and cardiovascular disease mechanisms. Am J Clin Nutr. 2006;83:456S-460S.
17. De Caterina R, Liao JK, Libby P. Fatty acid modulation of endothelial activation. Am J Clin Nutr. 2000;71:213S-223S. (Pubitemid 30046119)
18. Neish AS, Williams AJ, Palmer HJ, Whitley MZ, Collins T. Functional analysis of the human vascular cell adhesion molecule 1 promoter. J Exp Med. 1992;176:1583-1593.
19. Warfel JM, D'Agnillo F. Anthrax lethal toxin enhances TNF-induced endothelial VCAM-1 expression via an IFN regulatory factor-1-dependent mechanism. J Immunol. 2008;180:7516-7524.
20. Lechleitner S, Gille J, Johnson DR, Petzelbauer P. Interferon enhances tumor necrosis factor-induced vascular cell adhesion molecule 1 (cd106) expression in human endothelial cells by an interferon-related factor 1-dependent pathway. J Exp Med. 1998;187:2023-2030. (Pubitemid 28285571)
21. Harris TA, Yamakuchi M, Ferlito M, Mendell JT, Lowenstein CJ. MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc Natl Acad Sci USA. 2008;105:1516-1521. (Pubitemid 351346546)
22. Suarez Y, Wang C, Manes TD, Pober JS. Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of e-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation. J Immunol. 2010;184:21-25.
23. Bard JM, Charles MA, Juhan-Vague I, Vague P, Andre P, Safar M, Fruchart JC, Eschwege E. Accumulation of triglyceride-rich lipoprotein in subjects with abdominal obesity: the Biguanides and the Prevention of the Risk of Obesity (BIGPRO) 1 study. Arterioscler Thromb Vasc Biol. 2001;21:407-414. (Pubitemid 32199123)
24. Ziouzenkova O, Perrey S, Asatryan L, Hwang J, MacNaul KL, Moller DE, Rader DJ, Sevanian A, Zechner R, Hoefler G, Plutzky J. Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: evidence for an antiinflammatory role for lipoprotein lipase. Proc Natl Acad Sci USA. 2003;100:2730-2735. (Pubitemid 36297567)
25. Xu HE, Lambert MH, Montana VG, Parks DJ, Blanchard SG, Brown PJ, Sternbach DD, Lehmann JM, Wisely GB, Willson TM, Kliewer SA, Milburn MV. Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. Mol Cell. 1999;3:397-403. (Pubitemid 29290680)
26. Wong SW, Kwon MJ, Choi AM, Kim HP, Nakahira K, Hwang DH. Fatty acids modulate toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner. J Biol Chem. 2009;284:27384-27392.
27. Marx N, Sukhova GK, Collins T, Libby P, Plutzky J. PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation. 1999;99:3125-3131. (Pubitemid 29289077)
28. Schaeffler A, Gross P, Buettner R, Bollheimer C, Buechler C, Neumeier M, Kopp A, Schoelmerich J, Falk W. Fatty acid-induced induction of toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity. Immunology. 2009;126: 233-245.
29. Cao H, Gerhold K, Mayers JR, Wiest MM, Watkins SM, Hotamisligil GS. Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism. Cell. 2008;134:933-944.
30. Harvey KA, Walker CL, Xu Z, Whitley P, Pavlina TM, Hise M, Zaloga GP, Siddiqui RA. Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells. J Lipid Res. 2010;51:3470-3480.
31. Hart CM, Tolson JK, Block ER. Supplemental fatty acids alter lipid peroxidation and oxidant injury in endothelial cells. Am J Physiol. 1991;260:L481-L488.
32. Reissig D, Rassoul F, Salvetter J, Wagner O, Richter V. Effect of fatty acids on expression of endothelial leukocyte adhesion molecules. Eur J Nutr. 2003;42:224-227. (Pubitemid 36999074)
33. Wang L, Lim EJ, Toborek M, Hennig B. The role of fatty acids and caveolin-1 in tumor necrosis factor alpha-induced endothelial cell activation. Metabolism. 2008;57:1328-1339.
34. Nigam A, Frasure-Smith N, Lesperance F, Julien P. Relationship between n-3 and n-6 plasma fatty acid levels and insulin resistance in coronary patients with and without metabolic syndrome. Nutr Metab Cardiovasc Dis. 2009;19:264-270.
35. Goua M, Mulgrew S, Frank J, Rees D, Sneddon AA, Wahle KW. Regulation of adhesion molecule expression in human endothelial and smooth muscle cells by omega-3 fatty acids and conjugated linoleic acids: involvement of the transcription factor NF-kappaB? Prostagland Leukotriene Essent Fatty Acids. 2008;78:33-43.
36. Wang TM, Chen CJ, Lee TS, Chao HY, Wu WH, Hsieh SC, Sheu HH, Chiang AN. Docosahexaenoic acid attenuates VCAM-1 expression and NF-kappaB activation in TNF-alpha-treated human aortic endothelial cells. J Nutr Biochem. 2011;22:187-194.
37. Neish AS, Read MA, Thanos D, Pine R, Maniatis T, Collins T. Endothelial interferon regulatory factor 1 cooperates with NF-kappa B as a transcriptional activator of vascular cell adhesion molecule 1. Mol Cell Biol. 1995;15:2558-2569.
38. Neish AS, Khachigian LM, Park A, Baichwal VR, Collins T. Sp1 is a component of the cytokine-inducible enhancer in the promoter of vascular cell adhesion molecule-1. J Biol Chem. 1995;270:28903-28909.
39. Kielar ML, Jeyarajah DR, Penfield JG, Lu CY. Docosahexaenoic acid decreases IRF-1 mRNA and thus inhibits activation of both the IRF-E and NFkappa D response elements of the INOS promoter. Transplantation. 2000;69:2131-2137. (Pubitemid 30395049)
40. Harris TA, Yamakuchi M, Kondo M, Oettgen P, Lowenstein CJ. Ets-1 and ets-2 regulate the expression of microrna-126 in endothelial cells. Arterioscler Thromb Vasc Biol. 2010;30:1990-1997.