Tumor promoter-induced cellular senescence: Cell cycle arrest followed by geroconversion

Oncotarget

Volumn 5, Issue 24, 2014, Pages 12715-12727

  Leontieva, Olga V ^a   Blagosklonny, Mikhail V ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Aging; Cancer; MTOR; Phorbol ester; PMA; Rapalogs; Senescence; TPA

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL ESTER; PROTEIN KINASE B; PROTEIN P21; S6 KINASE; CARCINOGEN; PHORBOL 13 ACETATE 12 MYRISTATE; RAPAMYCIN;

ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CANCER INHIBITION; CELL AGING; CELL CYCLE ARREST; CELL PROLIFERATION; CELL STRUCTURE; CELLULAR PARAMETERS; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GEROCONVERSION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN TARGETING; SENESCENCE; SIGNAL TRANSDUCTION; TUMOR PROMOTION; BREAST TUMOR; CELL CYCLE CHECKPOINT; CHEMICALLY INDUCED; DRUG EFFECTS; DRUG INTERACTION; FEMALE; FIBROSARCOMA; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

BREAST NEOPLASMS; CARCINOGENS; CELL AGING; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG INTERACTIONS; FEMALE; FIBROSARCOMA; HUMANS; MAP KINASE SIGNALING SYSTEM; PHOSPHORYLATION; SIROLIMUS; TETRADECANOYLPHORBOL ACETATE;

EID: 84921326024     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3011     Document Type: Article

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