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Volumn 1, Issue 3, 2001, Pages 203-213

Cell senescence and cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; RNA; TELOMERASE; TELOMERASE RNA; TUMOR PROTEIN;

EID: 0035754079     PISSN: 1474175X     EISSN: None     Source Type: Journal    
DOI: 10.1038/35106045     Document Type: Article
Times cited : (239)

References (12)
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    • A biomarker that identifies senescent human cells in culture and in aging skin in vivo
    • Dimri, G. P. et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl Acad. Sci. USA 92, 9363-9367 (1995).
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    • Artandi, S. E. and DePinho, R. A. A critical role for telomeres in suppressing and facilitating carcinogenesis. Curr. Opin. Genet. Dev. 10, 39-46 (2000).
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    • Artandi, S.E.1    DePinho, R.A.2
  • 5
    • 0026055983 scopus 로고
    • Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1
    • Hara, E., Tsurui, H., Shinozaki, A., Nakada, S. and Oda, K. Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1. Biochem. Biophys. Res. Commun. 179, 528-534 (1991).
    • (1991) Biochem. Biophys. Res. Commun. , vol.179 , pp. 528-534
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  • 6
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    • A role for both RB and p53 in the regulation of human cellular senescence
    • Shay, J. W., Pereira-Smith, O. M. and Wright, W. E. A role for both RB and p53 in the regulation of human cellular senescence. Exp. Cell Res. 196, 33-39 (1991).
    • (1991) Exp. Cell Res. , vol.196 , pp. 33-39
    • Shay, J.W.1    Pereira-Smith, O.M.2    Wright, W.E.3
  • 7
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Hartey, C. B., Futcher, A. B. and Greider, C.W. Telomeres shorten during ageing of human fibroblasts. Nature 345, 458-460 (1990).
    • (1990) Nature , vol.345 , pp. 458-460
    • Hartey, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 8
    • 0010045614 scopus 로고    scopus 로고
    • Extension of life-span by introduction of telomerase into normal human cells
    • Bodnar, A. G. et al. Extension of life-span by introduction of telomerase into normal human cells. Science 279, 349-352 (1998).
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  • 9
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    • Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative We span
    • Vaziri, H. and Benchimol, S. Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative We span. Curr. Biol. 8, 279-282 (1998). References 8 and 9 show how telomerase expression immortalizes human cells.
    • (1998) Curr. Biol. , vol.8 , pp. 279-282
    • Vaziri, H.1    Benchimol, S.2
  • 10
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    • Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
    • Kiyono, T. et al. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 396, 84-88 (1998). Human epithelial cells seem to have, in addition to telomere shortening, a second checkpoint that determines replicative lifespan.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.