-
2
-
-
0034832956
-
Regulation of cellular senescence by p53
-
Itahana K, Dimri G, Campisi J. Regulation of cellular senescence by p53. Eur J Biochem 2001; 268:2784-91.
-
(2001)
Eur J Biochem
, vol.268
, pp. 2784-2791
-
-
Itahana, K.1
Dimri, G.2
Campisi, J.3
-
3
-
-
34248185454
-
P53: Guardian of the genome and policeman of the oncogenes
-
Efeyan A, Serrano M. p53: guardian of the genome and policeman of the oncogenes. Cell Cycle 2007; 6:1006-10. (Pubitemid 46708570)
-
(2007)
Cell Cycle
, vol.6
, Issue.9
, pp. 1006-1010
-
-
Efeyan, A.1
Serrano, M.2
-
4
-
-
70349442548
-
The first 30 years of p53: Growing ever more complex
-
Levine AJ, Oren M. The first 30 years of p53: growing ever more complex. Nat Rev Cancer 2009; 9:749-58.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 749-758
-
-
Levine, A.J.1
Oren, M.2
-
5
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
Vousden KH, Prives C. Blinded by the light: The growing complexity of p53. Cell 2009; 137:413-31.
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
6
-
-
70450270900
-
Awakening guardian angels: Drugging the p53 pathway
-
Brown CJ, Lain S, Verma CS, Fersht AR, Lane DP. Awakening guardian angels: drugging the p53 pathway. Nat Rev Cancer 2009; 9:862-73.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 862-873
-
-
Brown, C.J.1
Lain, S.2
Verma, C.S.3
Fersht, A.R.4
Lane, D.P.5
-
8
-
-
77955747085
-
The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway
-
Korotchkina LG, Leontieva OV, Bukreeva EI, Demidenko ZN, Gudkov AV, Blagosklonny MV. The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway. Aging 2010; 2:344-52.
-
(2010)
Aging
, vol.2
, pp. 344-352
-
-
Korotchkina, L.G.1
Leontieva, O.V.2
Bukreeva, E.I.3
Demidenko, Z.N.4
Gudkov, A.V.5
Blagosklonny, M.V.6
-
10
-
-
70349492724
-
Pharmacologic p53 Activation Blocks Cell Cycle Progression but Fails to Induce Senescence in Epithelial Cancer Cells
-
Huang B, Deo D, Xia M, Vassilev LT. Pharmacologic p53 Activation Blocks Cell Cycle Progression but Fails to Induce Senescence in Epithelial Cancer Cells. Mol Cancer Res 2009; 7:1497-509.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1497-1509
-
-
Huang, B.1
Deo, D.2
Xia, M.3
Vassilev, L.T.4
-
11
-
-
77955709042
-
Combination of nutlin-3 and VX-680 selectively targets p53 mutant cells with reversible effects on cells expressing wild-type p53
-
Cheok CF, Kua N, Kaldis P, Lane DP. Combination of nutlin-3 and VX-680 selectively targets p53 mutant cells with reversible effects on cells expressing wild-type p53. Cell Death Differ 2010; 17:1486-500.
-
(2010)
Cell Death Differ
, vol.17
, pp. 1486-1500
-
-
Cheok, C.F.1
Kua, N.2
Kaldis, P.3
Lane, D.P.4
-
12
-
-
33750346173
-
Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma
-
Van Maerken T, Speleman F, Vermeulen J, Lambertz I, De Clercq S, De Smet E, et al. Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma. Cancer Res 2006; 66:9646-55.
-
(2006)
Cancer Res
, vol.66
, pp. 9646-9655
-
-
Van Maerken, T.1
Speleman, F.2
Vermeulen, J.3
Lambertz, I.4
De Clercq, S.5
De Smet, E.6
-
13
-
-
34547625742
-
Induction of p53-dependent senescence by the MDM2 antagonist nutlin-3a in mouse cells of fibroblast origin
-
Efeyan A, Ortega-Molina A, Velasco-Miguel S, Herranz D, Vassilev LT, Serrano M. Induction of p53-dependent senescence by the MDM2 antagonist nutlin-3a in mouse cells of fibroblast origin. Cancer Res 2007; 67:7350-7.
-
(2007)
Cancer Res
, vol.67
, pp. 7350-7357
-
-
Efeyan, A.1
Ortega-Molina, A.2
Velasco-Miguel, S.3
Herranz, D.4
Vassilev, L.T.5
Serrano, M.6
-
14
-
-
4344610526
-
Small-molecule antagonists of p53-MDM2 binding: Research tools and potential therapeutics
-
Vassilev LT. Small-molecule antagonists of p53-MDM2 binding: Research tools and potential therapeutics. Cell Cycle 2004; 3:419-21.
-
(2004)
Cell Cycle
, vol.3
, pp. 419-421
-
-
Vassilev, L.T.1
-
15
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev LT, Vu BT, Graves B, Carvajal D, Podlaski F, Filipovic Z, et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 2004; 303:844-8.
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
-
16
-
-
77953641048
-
Reduced transcriptional activity in the p53 pathway of senescent cells revealed by the MDM2 antagonist nutlin-3
-
Huang B, Vassilev LT. Reduced transcriptional activity in the p53 pathway of senescent cells revealed by the MDM2 antagonist nutlin-3. Aging 2009; 1:845-54.
-
(2009)
Aging
, vol.1
, pp. 845-854
-
-
Huang, B.1
Vassilev, L.T.2
-
17
-
-
17444388849
-
A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents
-
Chang BD, Broude EV, Dokmanovic M, Zhu H, Ruth A, Xuan Y, et al. A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents. Cancer Res 1999; 59:3761-7.
-
(1999)
Cancer Res
, vol.59
, pp. 3761-3767
-
-
Chang, B.D.1
Broude, E.V.2
Dokmanovic, M.3
Zhu, H.4
Ruth, A.5
Xuan, Y.6
-
18
-
-
0033606852
-
waf1/cip1in senescencelike terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs
-
waf1/cip1 in senescencelike terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs. Oncogene 1999; 18:4808-18.
-
(1999)
Oncogene
, vol.18
, pp. 4808-4818
-
-
Chang, B.D.1
Xuan, Y.2
Broude, E.V.3
Zhu, H.4
Schott, B.5
Fang, J.6
-
20
-
-
50549087736
-
Growth stimulation leads to cellular senescence when the cell cycle is blocked
-
Demidenko ZN, Blagosklonny MV. Growth stimulation leads to cellular senescence when the cell cycle is blocked. Cell Cycle 2008; 7:3355-61.
-
(2008)
Cell Cycle
, vol.7
, pp. 3355-3361
-
-
Demidenko, Z.N.1
Blagosklonny, M.V.2
-
21
-
-
67649316033
-
Rapamycin decelerates cellular senescence
-
Demidenko ZN, Zubova SG, Bukreeva EI, Pospelov VA, Pospelova TV, Blagosklonny MV. Rapamycin decelerates cellular senescence. Cell Cycle 2009; 8:1888-95.
-
(2009)
Cell Cycle
, vol.8
, pp. 1888-1895
-
-
Demidenko, Z.N.1
Zubova, S.G.2
Bukreeva, E.I.3
Pospelov, V.A.4
Pospelova, T.V.5
Blagosklonny, M.V.6
-
22
-
-
35948967957
-
P53 determines multidrug sensitivity of childhood neuroblastoma
-
Xue C, Haber M, Flemming C, Marshall GM, Lock RB, MacKenzie KL, et al. p53 determines multidrug sensitivity of childhood neuroblastoma. Cancer Res 2007; 67:10351-60.
-
(2007)
Cancer Res
, vol.67
, pp. 10351-10360
-
-
Xue, C.1
Haber, M.2
Flemming, C.3
Marshall, G.M.4
Lock, R.B.5
MacKenzie, K.L.6
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