Role of p53 and p21(waf1/cip1) in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

Oncogene

Volumn 18, Issue 34, 1999, Pages 4808-4818

  Chang, Bey Dih ^a   Xuan, Yongzhi ^a   Broude, Eugenia V ^a   Zhu, Hongming ^a   Schott, Brigitte ^a   Fang, Jing ^a   Roninson, Igor B ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Cell death; Drug effects; p21; p53; Senescence

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN; PROTEIN P21; PROTEIN P53; BETA GALACTOSIDASE; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; FLUORESCENT DYE; ORGANIC COMPOUND; PKH2 GL; PKH2-GL;

ARTICLE; CANCER CELL CULTURE; CELL AGING; CELL DEATH; CELL PROLIFERATION; COLON CARCINOMA; CONTROLLED STUDY; DRUG CYTOTOXICITY; FIBROSARCOMA; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; MITOSIS INHIBITION; PRIORITY JOURNAL; PROMOTER REGION; CARCINOMA; CELL CULTURE; CELL DIVISION; COLON TUMOR; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; REGULATORY SEQUENCE;

ANTINEOPLASTIC AGENTS; BETA-GALACTOSIDASE; CARCINOMA; CELL AGING; CELL DEATH; CELL DIVISION; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DOXORUBICIN; FIBROSARCOMA; FLUORESCENT DYES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ORGANIC CHEMICALS; REGULATORY SEQUENCES, NUCLEIC ACID; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0033606852     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203078     Document Type: Article

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