Potential anti-aging agents suppress the level of constitutive mtorand DNA damage- signaling

Aging

Volumn 4, Issue 12, 2012, Pages 952-965

  Dorota Halicka, H ^a   Zhao, Hong ^a   Li, Jiangwei ^a   Lee, Yong Syu ^a   Hsieh, Tze Chen ^a   Wu, Joseph M ^a   Darzynkiewicz, Zbigniew ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

2 deoxyglucose; 4EBP1; Aspirin; Berberine; Calorie restriction; Cell cycle; H2AX phosphorylation; Metformin; Rapamycin; Replication stress; Resveratrol; Ribosomal protein S6; ROS; Senescence; Vitamin D3

Indexed keywords

ACETYLSALICYLIC ACID; ATM PROTEIN; BERBERINE; CELL CYCLE PROTEIN; COLECALCIFEROL; DEOXYGLUCOSE; DNA BINDING PROTEIN; EIF4EBP1 PROTEIN, HUMAN; H2AFX PROTEIN, HUMAN; HISTONE; METFORMIN; MTOR PROTEIN, HUMAN; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; RESVERATROL; S6 KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; STILBENE DERIVATIVE; TARGET OF RAPAMYCIN KINASE; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CELL AGING; DNA DAMAGE; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; LASER SCANNING CYTOMETRY; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; OXIDATIVE STRESS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ASPIRIN; BERBERINE; CELL AGING; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CHOLECALCIFEROL; DEOXYGLUCOSE; DNA DAMAGE; DNA-BINDING PROTEINS; DOWN-REGULATION; ENZYME ACTIVATION; FLOW CYTOMETRY; HISTONES; HUMANS; LASER SCANNING CYTOMETRY; MEMBRANE POTENTIAL, MITOCHONDRIAL; METFORMIN; MITOCHONDRIA; OXIDATIVE STRESS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; SIROLIMUS; STILBENES; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

EID: 84874925174     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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