Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TORindependent manner, by modulating housekeeping longevity assurance processes

Aging

Volumn 2, Issue 7, 2010, Pages 393-414

  Goldberg, Alexander A ^a   Richard, Vincent R ^a   Kyryakov, Pavlo ^a   Bourque, Simon D ^a   Beach, Adam ^a   Burstein, Michelle T ^a   Glebov, Anastasia ^a   Koupaki, Olivia ^a   Boukh Viner, Tatiana ^a   Gregg, Christopher ^a   Juneau, Mylène ^a   English, Ann M ^a   Thomas, David Y ^b   Titorenko, Vladimir I ^a  

^a Gina Cody School of Engineering and Computer Science   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Anti aging compounds; Caloric restriction; cellular aging; Chemical biology; Longevity; Yeast

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; LITHOCHOLIC ACID; RAPAMYCIN; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL PEPTIDE;

ARTICLE; BIOLOGICAL MODEL; CALORIC RESTRICTION; CELL AGING; GENETICS; HUMAN; LIPID METABOLISM; LONGEVITY; PHYSIOLOGY; YEAST;

CALORIC RESTRICTION; CELL AGING; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPID METABOLISM; LITHOCHOLIC ACID; LONGEVITY; MODELS, GENETIC; SACCHAROMYCES CEREVISIAE PROTEINS; SIROLIMUS; YEASTS;

EID: 78650799280     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100168     Document Type: Article

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