-
1
-
-
33645095226
-
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
-
Ng EW, Shima DT, Calias P, Cunningham ET Jr, Guyer DR, Adamis AP. Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nat. Rev. Drug Discov. 5(2), 123-132 (2006
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, Issue.2
, pp. 123-132
-
-
Ng, E.W.1
Shima, D.T.2
Calias, P.3
Cunningham, T.4
Guyer, D.R.5
Adamis, A.P.6
-
2
-
-
84870409612
-
Mipomersen: Evidence-based review of its potential in the treatment of homozygous and severe heterozygous familial hypercholesterolemia
-
Parhofer KG. Mipomersen: evidence-based review of its potential in the treatment of homozygous and severe heterozygous familial hypercholesterolemia. Core Evid. 7, 29-38 (2012
-
(2012)
Core Evid
, vol.7
, pp. 29-38
-
-
Parhofer, K.G.1
-
4
-
-
84877908608
-
Influence of diverse chemical modifications on the ADME characteristics and toxicology of antisense oligonucleotides
-
Dirin M, Winkler J. Influence of diverse chemical modifications on the ADME characteristics and toxicology of antisense oligonucleotides. Expert Opin. Biol. Ther. 13(6), 875-888 (2013
-
(2013)
Expert Opin. Biol. Ther
, vol.13
, Issue.6
, pp. 875-888
-
-
Dirin, M.1
Winkler, J.2
-
5
-
-
84896705346
-
Review of Phase II and Phase III clinical trials for Duchenne muscular dystrophy
-
Scully MA, Pandya S, Moxley RT. Review of Phase II and Phase III clinical trials for Duchenne muscular dystrophy. Expert Opin. Orphan Drugs 1(1), 33-46 (2013
-
(2013)
Expert Opin. Orphan Drugs
, vol.1
, Issue.1
, pp. 33-46
-
-
Scully, M.A.1
Pandya, S.2
Moxley, R.T.3
-
6
-
-
0032545933
-
Potent and specific genetic interference by doublestranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by doublestranded RNA in Caenorhabditis elegans. Nature 391(6669), 806-811 (1998
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
7
-
-
79961203099
-
Nanomedicines based on recombinant fusion proteins for targeting therapeutic siRNA oligonucleotides
-
Winkler J. Nanomedicines based on recombinant fusion proteins for targeting therapeutic siRNA oligonucleotides. Ther. Deliv. 2(7), 891-905 (2011
-
(2011)
Ther. Deliv
, vol.2
, Issue.7
, pp. 891-905
-
-
Winkler, J.1
-
9
-
-
76349111051
-
Rational design of cationic lipids for siRNA delivery
-
Semple SC, Akinc A, Chen J et al. Rational design of cationic lipids for siRNA delivery. Nat. Biotechnol. 28(2), 172-176 (2010
-
(2010)
Nat. Biotechnol
, vol.28
, Issue.2
, pp. 172-176
-
-
Semple, S.C.1
Akinc, A.2
Chen, J.3
-
10
-
-
84880915038
-
Oligonucleotide conjugates for therapeutic applications
-
Winkler J. Oligonucleotide conjugates for therapeutic applications. Ther. Deliv. 4(7), 791-809 (2013
-
(2013)
Ther. Deliv
, vol.4
, Issue.7
, pp. 791-809
-
-
Winkler, J.1
-
11
-
-
84863922166
-
Lipid-based nanoparticles for siRNA delivery in cancer therapy: Paradigms and challenges
-
Gomes-da-Silva LC, Fonseca NA, Moura V, Pedroso de Lima MC, Simoes S, Moreira JN. Lipid-based nanoparticles for siRNA delivery in cancer therapy: paradigms and challenges. Acc. Chem. Res. 45(7), 1163-1171 (2012
-
(2012)
Acc. Chem. Res
, vol.45
, Issue.7
, pp. 1163-1171
-
-
Gomes-Da-Silva, L.C.1
Fonseca, N.A.2
Moura, V.3
Pedroso De Lima, M.C.4
Simoes, S.5
Moreira, J.N.6
-
12
-
-
77954243341
-
Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms
-
Akinc A, Querbes W, De S et al. Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms. Mol. Ther. 18(7), 1357-1364 (2010
-
(2010)
Mol. Ther
, vol.18
, Issue.7
, pp. 1357-1364
-
-
Akinc, A.1
Querbes, W.2
De, S.3
-
13
-
-
83455206025
-
MicroRNAs and cancer therapeutics
-
Yeung ML, Jeang KT. MicroRNAs and cancer therapeutics. Pharm. Res. 28(12), 3043-3049 (2011
-
(2011)
Pharm. Res
, vol.28
, Issue.12
, pp. 3043-3049
-
-
Yeung, M.L.1
Jeang, K.T.2
-
14
-
-
84859464569
-
Blood cell origin of circulating micrornas a cautionary note for cancer biomarker studies
-
Pritchard CC, Kroh E, Wood B et al. Blood cell origin of circulating micrornas. a cautionary note for cancer biomarker studies. Cancer Prev. Res. (Phila.) 5(3), 492-497 (2012
-
(2012)
Cancer Prev. Res. (Phila
, vol.5
, Issue.3
, pp. 492-497
-
-
Pritchard, C.C.1
Kroh, E.2
Wood, B.3
-
15
-
-
84877258007
-
Treatment of HCV infection by targeting microRNA
-
Janssen HLA, Reesink HW, Lawitz EJ et al. Treatment of HCV infection by targeting microRNA. N. Engl. J. Med. 368(18), 1685-1694 (2013
-
(2013)
N. Engl. J. Med
, vol.368
, Issue.18
, pp. 1685-1694
-
-
Janssen, H.L.A.1
Reesink, H.W.2
Lawitz, E.J.3
-
16
-
-
84891765459
-
Miravirsen (SPC3649) can inhibit the biogenesis of miR?122
-
Gebert LFR, Rebhan MAE, Crivelli SEM, Denzler R, Stoffel M, Hall J. Miravirsen (SPC3649) can inhibit the biogenesis of miR?122. Nucleic Acids Res. 42(1), 609-621 (2014
-
(2014)
Nucleic Acids Res
, vol.42
, Issue.1
, pp. 609-621
-
-
Gebert, L.F.R.1
Rebhan, M.A.E.2
Crivelli, S.E.M.3
Denzler, R.4
Stoffel, M.5
Hall, J.6
-
17
-
-
79751473114
-
The microRNA miR?34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
-
Liu C, Kelnar K, Liu B et al. The microRNA miR?34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat. Med. 17(2), 211-215 (2011
-
(2011)
Nat. Med
, vol.17
, Issue.2
, pp. 211-215
-
-
Liu, C.1
Kelnar, K.2
Liu, B.3
-
18
-
-
0027751663
-
The C elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854 (1993
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
19
-
-
0035955361
-
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
-
Lau NC, Lim LP, Weinstein EG, Bartel DP. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294, 858-862 (2001
-
(2001)
Science
, vol.294
, pp. 858-862
-
-
Lau, N.C.1
Lim, L.P.2
Weinstein, E.G.3
Bartel, D.P.4
-
20
-
-
0035955406
-
Glimpses of a tiny RNA world
-
Ruvkun G. Glimpses of a tiny RNA world. Science 797-799 (2001
-
(2001)
Science
, pp. 797-799
-
-
Ruvkun, G.1
-
21
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, Snyder M. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Bernstein, B.E.1
Birney, E.2
Dunham, I.3
Green, E.D.4
Gunter, C.5
Snyder, M.6
-
22
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee Y, Kim M, Han J et al MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 23, 4051-4060 (2004
-
(2004)
EMBO J.
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
-
24
-
-
0037772254
-
The time of appearance of the C elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter
-
Johnson SM, Lin S-Y, Slack FJ. The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter. Dev. Biol. 259, 364-379 (2003
-
(2003)
Dev. Biol
, vol.259
, pp. 364-379
-
-
Johnson, S.M.1
Lin, S.-Y.2
Slack, F.J.3
-
25
-
-
84873525693
-
Identification and analysis of the proximal promoters of microRNA genes in Arabidopsis
-
Zhao X, Zhang H, Li L. Identification and analysis of the proximal promoters of microRNA genes in Arabidopsis. Genomics 101, 187-194 (2013
-
(2013)
Genomics
, vol.101
, pp. 187-194
-
-
Zhao, X.1
Zhang, H.2
Li, L.3
-
26
-
-
0037009364
-
MicroRNA maturation: Stepwise processing and subcellular localization
-
Lee Y, Jeon K, Lee JT, Kim S, Kim VN. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J. 21, 4663-4670 (2002
-
(2002)
EMBO J.
, vol.21
, pp. 4663-4670
-
-
Lee, Y.1
Jeon, K.2
Lee, J.T.3
Kim, S.4
Kim, V.N.5
-
27
-
-
33744520104
-
Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
-
Han J, Lee Y, Yeom K-H et al. Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125, 887-901 (2006
-
(2006)
Cell
, vol.125
, pp. 887-901
-
-
Han, J.1
Lee, Y.2
Yeom, K.-H.3
-
28
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 17, 3011-3016 (2003
-
(2003)
Genes Dev
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
MacAra, I.G.3
Cullen, B.R.4
-
29
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E, Güttinger S, Calado A, Dahlberg JE, Kutay U. Nuclear export of microRNA precursors. Science 303, 95-98 (2004
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Güttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
30
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C elegans
-
Ketting RF, Fischer SEJ, Bernstein E, Sijen T, Hannon GJ, Plasterk RHA. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15(20), 2654-2659 (2001
-
(2001)
Genes Dev
, vol.15
, Issue.20
, pp. 2654-2659
-
-
Ketting, R.F.1
Fischer, S.E.J.2
Bernstein, E.3
Sijen, T.4
Hannon, G.J.5
Plasterk, R.H.A.6
-
31
-
-
0036845374
-
Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
-
Zhang H, Kolb FA, Brondani V, Billy E, Filipowicz W. Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J. 21, 5875-5885 (2002
-
(2002)
EMBO J.
, vol.21
, pp. 5875-5885
-
-
Zhang, H.1
Kolb, F.A.2
Brondani, V.3
Billy, E.4
Filipowicz, W.5
-
32
-
-
0038076109
-
Negative feedback regulation of dicer-like1 in Arabidopsis by microRNA-guided mRNA degradation
-
Xie Z, Kasschau K, Carrington J. Negative feedback regulation of dicer-like1 in Arabidopsis by microRNA-guided mRNA degradation. Curr. Biol. 13, 784-789 (2003
-
(2003)
Curr. Biol
, vol.13
, pp. 784-789
-
-
Xie, Z.1
Kasschau, K.2
Carrington, J.3
-
33
-
-
23644433363
-
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
-
Chendrimada TP, Gregory RI, Kumaraswamy E et al. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436(7051), 740-744 (2005
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 740-744
-
-
Chendrimada, T.P.1
Gregory, R.I.2
Kumaraswamy, E.3
-
34
-
-
26944431852
-
Small RNA asymmetry in RNAi: Function in RISC assembly and gene regulation
-
Hutvagner G. Small RNA asymmetry in RNAi: function in RISC assembly and gene regulation. FEBS Lett. 579, 5850-5857 (2005
-
(2005)
FEBS Lett
, vol.579
, pp. 5850-5857
-
-
Hutvagner, G.1
-
35
-
-
5144225452
-
Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity
-
Rand TA, Ginalski K, Grishin NV, Wang X. Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity. Proc. Natl Acad. Sci. USA 101, 14385-14389 (2004
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 14385-14389
-
-
Rand, T.A.1
Ginalski, K.2
Grishin, N.V.3
Wang, X.4
-
36
-
-
33644768174
-
Control of translation and mRNA degradation by miRNAs and siRNAs
-
Valencia-Sanchez MA, Liu J, Hannon GJ, Parker R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev. 20, 515-524 (2006
-
(2006)
Genes Dev
, vol.20
, pp. 515-524
-
-
Valencia-Sanchez, M.A.1
Liu, J.2
Hannon, G.J.3
Parker, R.4
-
37
-
-
0142173075
-
Small RNAs with imperfect match to endogenous mRNA repress translation Implications for off-target activity of small inhibitory RNA in mammalian cells
-
Saxena S, Jónsson ZO, Dutta A. Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells. J. Biol. Chem. 278, 44312-44319 (2003
-
(2003)
J. Biol. Chem
, vol.278
, pp. 44312-44319
-
-
Saxena, S.1
Jónsson, Z.O.2
Dutta, A.3
-
38
-
-
20944450160
-
Combinatorial microRNA target predictions
-
Krek A, Grün D, Poy MN et al. Combinatorial microRNA target predictions. Nat. Genet. 37, 495-500 (2005
-
(2005)
Nat. Genet
, vol.37
, pp. 495-500
-
-
Krek, A.1
Grün, D.2
Poy, M.N.3
-
39
-
-
32444436121
-
Short RNAs repress translation after initiation in mammalian cells
-
Petersen CP, Bordeleau M-E, Pelletier J, Sharp PA. Short RNAs repress translation after initiation in mammalian cells. Mol. Cell 21, 533-542 (2006
-
(2006)
Mol. Cell
, vol.21
, pp. 533-542
-
-
Petersen, C.P.1
Bordeleau, M.-E.2
Pelletier, J.3
Sharp, P.A.4
-
40
-
-
79956227111
-
Shielding the messenger (RNA): MicroRNA-based anticancer therapies
-
Sotillo E, Thomas-Tikhonenko A. Shielding the messenger (RNA): microRNA-based anticancer therapies. Pharmacol. Ther. 131, 18-32 (2011
-
(2011)
Pharmacol. Ther
, vol.131
, pp. 18-32
-
-
Sotillo, E.1
Thomas-Tikhonenko, A.2
-
41
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20 (2005
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
42
-
-
84896396537
-
MicroRNA-targeting therapeutics for hepatitis C
-
Baek J, Kang S, Min H. MicroRNA-targeting therapeutics for hepatitis C. Arch. Pharm. Res. 37(3), 299-305 (2014
-
(2014)
Arch. Pharm. Res
, vol.37
, Issue.3
, pp. 299-305
-
-
Baek, J.1
Kang, S.2
Min, H.3
-
43
-
-
84878108145
-
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2
-
Shen J, Xia W, Khotskaya YB et al. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature 497, 383-387 (2013
-
(2013)
Nature
, vol.497
, pp. 383-387
-
-
Shen, J.1
Xia, W.2
Khotskaya, Y.B.3
-
44
-
-
82755189644
-
MicroRNA history: Discovery, recent applications, and next frontiers
-
Almeida MI, Reis RM, Calin GA. MicroRNA history: discovery, recent applications, and next frontiers. Mutat. Res. 717, 1-8 (2011
-
(2011)
Mutat. Res
, vol.717
, pp. 1-8
-
-
Almeida, M.I.1
Reis, R.M.2
Calin, G.A.3
-
45
-
-
81855224576
-
Epigenetics and genetics MicroRNAs en route to the clinic: Progress in validating and targeting microRNAs for cancer therapy
-
Kasinski AL, Slack FJ. Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat. Rev. Cancer 11, 849-864 (2011
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 849-864
-
-
Kasinski, A.L.1
Slack, F.J.2
-
47
-
-
84878112868
-
MiRNAs and cancer: An epigenetics view
-
Malumbres M. miRNAs and cancer: an epigenetics view. Mol. Aspects Med. 34, 863-874 (2013
-
(2013)
Mol. Aspects Med
, vol.34
, pp. 863-874
-
-
Malumbres, M.1
-
48
-
-
84877317891
-
Cross-platform microarray meta-analysis for the mouse jejunum selects novel reference genes with highly uniform levels of expression
-
Meyer FRL, Grausgruber H, Binter C et al. Cross-platform microarray meta-analysis for the mouse jejunum selects novel reference genes with highly uniform levels of expression. PLoS ONE 8, e63125 (2013
-
(2013)
PLoS ONE
, vol.8
, pp. e63125
-
-
Meyer, F.R.L.1
Grausgruber, H.2
Binter, C.3
-
49
-
-
33645241407
-
The RIN: An RNA integrity number for assigning integrity values to RNA measurements
-
Schroeder A, Mueller O, Stocker S et al. The RIN: an RNA integrity number for assigning integrity values to RNA measurements. BMC Mol. Biol. 7, 3 (2006
-
(2006)
BMC Mol. Biol
, vol.7
, pp. 3
-
-
Schroeder, A.1
Mueller, O.2
Stocker, S.3
-
50
-
-
42449098100
-
Normalization of microRNA expression levels in quantitative RT-PCR assays: Identification of suitable reference RNA targets in normal and cancerous human solid
-
Peltier H, Latham G. Normalization of microRNA expression levels in quantitative RT-PCR assays: identification of suitable reference RNA targets in normal and cancerous human solid. RNA 14(5), 844-852 (2008
-
(2008)
RNA
, vol.14
, Issue.5
, pp. 844-852
-
-
Peltier, H.1
Latham, G.2
-
51
-
-
0035161457
-
Unsuitability of using ribosomal RNA as loading control for Northern blot analyses related to the imbalance between messenger and ribosomal RNA content in rat mammary tumors
-
Solanas M, Moral R, Escrich E. Unsuitability of using ribosomal RNA as loading control for Northern blot analyses related to the imbalance between messenger and ribosomal RNA content in rat mammary tumors. Anal. Biochem. 288, 99-102 (2001
-
(2001)
Anal. Biochem
, vol.288
, pp. 99-102
-
-
Solanas, M.1
Moral, R.2
Escrich, E.3
-
52
-
-
84864967988
-
Selective depletion of rRNA enables whole transcriptome profiling of archival fixed tissue
-
Morlan JD, Qu K, Sinicropi DV. Selective depletion of rRNA enables whole transcriptome profiling of archival fixed tissue. PLoS ONE 7, e42882 (2012
-
(2012)
PLoS ONE
, vol.7
, pp. e42882
-
-
Morlan, J.D.1
Qu, K.2
Sinicropi, D.V.3
-
53
-
-
84879692466
-
Comparative analysis of RNA sequencing methods for degraded or lowinput samples
-
Adiconis X, Borges-Rivera D, Satija R et al. Comparative analysis of RNA sequencing methods for degraded or lowinput samples. Nat. Methods 10, 623-629 (2013
-
(2013)
Nat. Methods
, vol.10
, pp. 623-629
-
-
Adiconis, X.1
Borges-Rivera, D.2
Satija, R.3
-
54
-
-
79953207276
-
The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis
-
Gee HE, Buffa FM, Camps C et al. The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis. Br. J. Cancer 104, 1168-1177 (2011
-
(2011)
Br. J. Cancer
, vol.104
, pp. 1168-1177
-
-
Gee, H.E.1
Buffa, F.M.2
Camps, C.3
-
55
-
-
29144470346
-
Real-time quantification of microRNAs by stem-loop RT-PCR
-
Chen C, Ridzon Da, Broomer AJ et al. Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res. 33, e179 (2005
-
(2005)
Nucleic Acids Res
, vol.33
, pp. e179
-
-
Chen, C.1
Ridzon Da Broomer, A.J.2
-
56
-
-
38849140922
-
Protocol: A highly sensitive RT-PCR method for detection and quantification of microRNAs
-
Varkonyi-Gasic E, Wu R, Wood M, Walton EF, Hellens RP. Protocol: a highly sensitive RT-PCR method for detection and quantification of microRNAs. Plant Methods 3, 12 (2007
-
(2007)
Plant Methods
, vol.3
, pp. 12
-
-
Varkonyi-Gasic, E.1
Wu, R.2
Wood, M.3
Walton, E.F.4
Hellens, R.P.5
-
57
-
-
84869008360
-
A Novel Real-Time PCR Assay of microRNAs Using S-Poly(T), a Specific Oligo(dT) Reverse Transcription Primer with Excellent Sensitivity and Specificity
-
Kang K, Xiaoying Z, Hongtao L et al. A Novel Real-Time PCR Assay of microRNAs Using S-Poly(T), a Specific Oligo(dT) Reverse Transcription Primer with Excellent Sensitivity and Specificity. PLoS ONE 7(11), e48536 (2012
-
(2012)
PLoS ONE
, vol.7
, Issue.11
, pp. e48536
-
-
Kang, K.1
Xiaoying, Z.2
Hongtao, L.3
-
58
-
-
64149097786
-
The MIQE guidelines minimum information for publication of quantitative realtime PCR experiments
-
Bustin SA, Benes V, Garson JA et al. The MIQE guidelines. minimum information for publication of quantitative realtime PCR experiments. Clin. Chem. 55, 611-622 (2009
-
(2009)
Clin. Chem
, vol.55
, pp. 611-622
-
-
Bustin, S.A.1
Benes, V.2
Garson, J.A.3
-
59
-
-
18744396337
-
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, Dumitru CD, Shimizu M et al. Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl Acad. Sci. USA 99, 15524-15529 (2002
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
-
60
-
-
84896703318
-
Clinical relevance of circulating cell-free microRNAs in cancer
-
Schwarzenbach H, Nishida N, Calin GA, Pantel K. Clinical relevance of circulating cell-free microRNAs in cancer. Nat. Rev. Clin. Onocl. 11(3), 145-156 (2014
-
(2014)
Nat. Rev. Clin. Onocl
, vol.11
, Issue.3
, pp. 145-156
-
-
Schwarzenbach, H.1
Nishida, N.2
Calin, G.A.3
Pantel, K.4
-
61
-
-
84865062501
-
Molecular Pathways: MicroRNAs as cancer therapeutics
-
Melo SA, Kalluri R. Molecular Pathways: microRNAs as cancer therapeutics. Clin. Cancer Res. 18(16), 4234-4239 (2012
-
(2012)
Clin. Cancer Res
, vol.18
, Issue.16
, pp. 4234-4239
-
-
Melo, S.A.1
Kalluri, R.2
-
63
-
-
53349177819
-
Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases
-
Chen X, Ba Y, Ma L et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 18, 997-1006 (2008
-
(2008)
Cell Res
, vol.18
, pp. 997-1006
-
-
Chen, X.1
Ba, Y.2
Ma, L.3
-
64
-
-
77953192081
-
Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer
-
Huang Z, Huang D, Ni S, Peng Z, Sheng W, Du X. Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer. Int. J. Cancer 127, 118-126 (2010
-
(2010)
Int. J. Cancer
, vol.127
, pp. 118-126
-
-
Huang, Z.1
Huang, D.2
Ni, S.3
Peng, Z.4
Sheng, W.5
Du, X.6
-
65
-
-
82755187564
-
Extracellular microRNA: A new source of biomarkers
-
Etheridge A, Lee I, Hood L, Galas D, Wang K. Extracellular microRNA: a new source of biomarkers. Mutat. Res. 717, 85-90 (2011
-
(2011)
Mutat. Res
, vol.717
, pp. 85-90
-
-
Etheridge, A.1
Lee, I.2
Hood, L.3
Galas, D.4
Wang, K.5
-
67
-
-
84857672136
-
Metastami Rs non-coding microRNAs driving cancer invasion and metastasis
-
Lopez-Camarillo C, Marchat LA, Arechaga-Ocampo E et al. MetastamiRs. non-coding microRNAs driving cancer invasion and metastasis. Int. J. Mol. Sci. 13, 1347-1379 (2012
-
(2012)
Int. J. Mol. Sci
, vol.13
, pp. 1347-1379
-
-
Lopez-Camarillo, C.1
Marchat, L.A.2
Arechaga-Ocampo, E.3
-
68
-
-
84895980587
-
Regulation of microRNAs in cancer metastasis
-
Bouyssou JMC, Manier S, Huynh D, Issa S, Roccaro AM, Ghobrial IM. Regulation of microRNAs in cancer metastasis. Biochim. Biophys. Acta 1845(2), 255-265 (2014
-
(2014)
Biochim. Biophys. Acta
, vol.1845
, Issue.2
, pp. 255-265
-
-
Bouyssou, J.M.C.1
Manier, S.2
Huynh, D.3
Issa, S.4
Roccaro, A.M.5
Ghobrial, I.M.6
-
69
-
-
84893649514
-
The role of microRNAs in the regulation of cancer stem cells
-
Takahashi R-U, Miyazaki H, Ochiya T. The role of microRNAs in the regulation of cancer stem cells. Front. Genet. 4, 295 (2014
-
(2014)
Front. Genet
, vol.4
, Issue.295
-
-
Takahashi, R.-U.1
Miyazaki, H.2
Ochiya, T.3
-
70
-
-
84867740278
-
MicroRNAs involved in regulating epithelial-mesenchymal transition and cancer stem cells as molecular targets for cancer therapeutics
-
Xia H, Hui KM. MicroRNAs involved in regulating epithelial-mesenchymal transition and cancer stem cells as molecular targets for cancer therapeutics. Cancer Gene Ther. 19, 723-730 (2012
-
(2012)
Cancer Gene Ther
, vol.19
, pp. 723-730
-
-
Xia, H.1
Hui, K.M.2
-
71
-
-
80055092259
-
MicroRNAs, an active and versatile group in cancers
-
Liu J, Zheng M, Tang YL, Liang X-H, Yang Q. MicroRNAs, an active and versatile group in cancers. Int. J. Oral Sci. 3, 165-175 (2011
-
(2011)
Int. J. Oral Sci
, vol.3
, pp. 165-175
-
-
Liu, J.1
Zheng, M.2
Tang, Y.L.3
Liang, X.-H.4
Yang, Q.5
-
72
-
-
22244467087
-
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
-
Chan Ja, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 65, 6029-6033 (2005
-
(2005)
Cancer Res
, vol.65
, pp. 6029-6033
-
-
Chan, J.A.1
Krichevsky, A.M.2
Kosik, K.S.3
-
73
-
-
25444520537
-
MiR?15 and miR?16 induce apoptosis by targeting BCL2
-
Cimmino A, Calin G. miR?15 and miR?16 induce apoptosis by targeting BCL2. Proc. Natl Acad. Sci. USA 103, (2005
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.103
-
-
Cimmino, A.1
Calin, G.2
-
74
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson SM, Grosshans H, Shingara J et al. RAS is regulated by the let-7 microRNA family. Cell 120, 635-647 (2005
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
-
75
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin GA, Sevignani C, Dumitru CD et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl Acad. Sci. USA 101, 2999-3004 (2004
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
-
76
-
-
84878529330
-
CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia
-
Chen Y, Jacamo R, Konopleva M, Garzon R, Croce C, Andreeff M. CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia. J. Clin. Invest. 123(6), 2395-2407 (2013
-
(2013)
J. Clin. Invest
, vol.123
, Issue.6
, pp. 2395-2407
-
-
Chen, Y.1
Jacamo, R.2
Konopleva, M.3
Garzon, R.4
Croce, C.5
Andreeff, M.6
-
77
-
-
78650385772
-
MicroRNA-21: A novel therapeutic target in human cancer
-
Pan X, Wang Z-X, Wang R. MicroRNA-21: a novel therapeutic target in human cancer. Cancer Biol. Ther. 10(12), 1224-1232 (2010
-
(2010)
Cancer Biol. Ther
, vol.10
, Issue.12
, pp. 1224-1232
-
-
Pan, X.1
Wang, Z.-X.2
Wang, R.3
-
78
-
-
84869219338
-
MiR?34 - A microRNA replacement therapy is headed to the clinic
-
Bader AG. miR?34 - a microRNA replacement therapy is headed to the clinic. Front. Genet. 3, 120 (2012
-
(2012)
Front. Genet
, vol.3
, Issue.120
-
-
Bader, A.G.1
-
79
-
-
84888013022
-
MiR?137 suppresses cell growth in ovarian cancer by targeting AEG-1
-
Guo J, Xia B, Meng F, Lou G. miR?137 suppresses cell growth in ovarian cancer by targeting AEG-1. Biochem. Biophys. Res. Commun. 441, 357-363 (2013
-
(2013)
Biochem. Biophys. Res. Commun
, vol.441
, pp. 357-363
-
-
Guo, J.1
Xia, B.2
Meng, F.3
Lou, G.4
-
80
-
-
84871716820
-
MiR?137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6
-
Zhu X, Li Y, Shen H et al. miR?137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6. FEBS Lett. 587, 73-81 (2013
-
(2013)
FEBS Lett
, vol.587
, pp. 73-81
-
-
Zhu, X.1
Li, Y.2
Shen, H.3
-
81
-
-
84864183740
-
MiR-145 modulates multiple components of the insulin-like growth factor pathway in hepatocellular carcinoma
-
Law PTY, Ching AKK, Chan AWH et al. MiR-145 modulates multiple components of the insulin-like growth factor pathway in hepatocellular carcinoma. Carcinogenesis 33, 1134-1141 (2012
-
(2012)
Carcinogenesis
, vol.33
, pp. 1134-1141
-
-
Law, P.T.Y.1
Ching, A.K.K.2
Chan, A.W.H.3
-
82
-
-
84899490560
-
MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling
-
Wang Y, Hu C, Cheng J et al. MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling. Biochem. Biophys. Res. Commun. 446, 1255-1260 (2014
-
(2014)
Biochem. Biophys. Res. Commun
, vol.446
, pp. 1255-1260
-
-
Wang, Y.1
Hu, C.2
Cheng, J.3
-
83
-
-
84874444612
-
MiRNA-145 targets v-ets erythroblastosis virus E26 oncogene homolog 1 to suppress the invasion, metastasis, and angiogenesis of gastric cancer cells
-
Zheng L, Pu J, Qi T et al. miRNA-145 targets v-ets erythroblastosis virus E26 oncogene homolog 1 to suppress the invasion, metastasis, and angiogenesis of gastric cancer cells. Mol. Cancer Res. 11, 182-193 (2013
-
(2013)
Mol. Cancer Res
, vol.11
, pp. 182-193
-
-
Zheng, L.1
Pu, J.2
Qi, T.3
-
84
-
-
84895417104
-
MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis
-
Chan SH, Huang WC, Chang JW et al. MicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasis. Oncogene 33(36), 4496-4507 (2014
-
(2014)
Oncogene
, vol.33
, Issue.36
, pp. 4496-4507
-
-
Chan, S.H.1
Huang, W.C.2
Chang, J.W.3
-
85
-
-
80053139025
-
MicroRNA-149, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma
-
Jin L, Hu WL, Jiang CC et al. MicroRNA-149. a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma. Proc. Natl Acad. Sci. USA 108(38), 15840-15845 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.38
, pp. 15840-15845
-
-
Jin, L.1
Hu, W.L.2
Jiang, C.C.3
-
86
-
-
84888204275
-
MicroRNA-181a enhances the chemoresistance of human cervical squamous cell carcinoma to cisplatin by targeting PRKCD
-
Chen Y, Ke G, Han D, Liang S, Yang G, Wu X. MicroRNA-181a enhances the chemoresistance of human cervical squamous cell carcinoma to cisplatin by targeting PRKCD. Exp. Cell Res. 320, 12-20 (2014
-
(2014)
Exp. Cell Res
, vol.320
, pp. 12-20
-
-
Chen, Y.1
Ke, G.2
Han, D.3
Liang, S.4
Yang, G.5
Wu, X.6
-
87
-
-
84888008102
-
MiR?181a-Twist1 pathway in the chemoresistance of tongue squamous cell carcinoma
-
Liu M, Wang J, Huang H, Hou J, Zhang B, Wang A. miR?181a-Twist1 pathway in the chemoresistance of tongue squamous cell carcinoma. Biochem. Biophys. Res. Commun. 441, 364-370 (2013
-
(2013)
Biochem. Biophys. Res. Commun
, vol.441
, pp. 364-370
-
-
Liu, M.1
Wang, J.2
Huang, H.3
Hou, J.4
Zhang, B.5
Wang, A.6
-
88
-
-
81855206547
-
Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR?210 expression caused by stabilizing HIF-1?.
-
Wang H, Bian S, Yang CS. Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR?210 expression caused by stabilizing HIF-1?. Carcinogenesis 32, 1881-1889 (2011
-
(2011)
Carcinogenesis
, vol.32
, pp. 1881-1889
-
-
Wang, H.1
Bian, S.2
Yang, C.S.3
-
89
-
-
79952751773
-
MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway
-
Alajez NM, Lenarduzzi M, Ito E et al. MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway. Cancer Res. 71, 2381-2391 (2011
-
(2011)
Cancer Res
, vol.71
, pp. 2381-2391
-
-
Alajez, N.M.1
Lenarduzzi, M.2
Ito, E.3
-
90
-
-
84899674559
-
MiR-330-mediated regulation of SH3GL2 expression enhances malignant behaviors of glioblastoma stem cells by activating ERK and PI3K/AKT signaling pathways
-
Yao Y, Xue Y, Ma J et al. MiR-330-mediated regulation of SH3GL2 expression enhances malignant behaviors of glioblastoma stem cells by activating ERK and PI3K/AKT signaling pathways. PLoS ONE 9, e95060 (2014
-
(2014)
PLoS ONE
, vol.9
, pp. e95060
-
-
Yao, Y.1
Xue, Y.2
Ma, J.3
-
91
-
-
84873745294
-
Yan J. MiR?330 regulates the proliferation of colorectal cancer cells by targeting Cdc42
-
Li Y, Zhu X, Xu W, Wang D, Yan J. miR?330 regulates the proliferation of colorectal cancer cells by targeting Cdc42. Biochem. Biophys. Res. Commun. 431, 560-565 (2013
-
(2013)
Biochem. Biophys. Res. Commun
, vol.431
, pp. 560-565
-
-
Li, Y.1
Zhu, X.2
Xu, W.3
Wang, D.4
-
92
-
-
84899723953
-
MicroRNA-338 inhibits growth, invasion and metastasis of gastric cancer by targeting NRP1 expression
-
Peng Y, Liu YM, Li LC, Wang LL, Wu XL. MicroRNA-338 inhibits growth, invasion and metastasis of gastric cancer by targeting NRP1 expression. PLoS ONE 9, e94422 (2014
-
(2014)
PLoS ONE
, vol.9
, pp. e94422
-
-
Peng, Y.1
Liu, Y.M.2
Li, L.C.3
Wang, L.L.4
Wu, X.L.5
-
93
-
-
84896442949
-
MicroRNA-363-mediated downregulation of S1PR1 suppresses the proliferation of hepatocellular carcinoma cells
-
Zhou P, Huang G, Zhao Y et al. MicroRNA-363-mediated downregulation of S1PR1 suppresses the proliferation of hepatocellular carcinoma cells. Cell Signal 26, 1347-1354 (2014
-
(2014)
Cell Signal
, vol.26
, pp. 1347-1354
-
-
Zhou, P.1
Huang, G.2
Zhao, Y.3
-
94
-
-
84899624549
-
A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via upregulation of miRNA-4284 and JNK/AP-1 signaling
-
Yang F, Nam S, Brown CE et al. A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via upregulation of miRNA-4284 and JNK/AP-1 signaling. PLoS ONE 9, e94443 (2014
-
(2014)
PLoS ONE
, vol.9
, pp. e94443
-
-
Yang, F.1
Nam, S.2
Brown, C.E.3
-
95
-
-
34248217444
-
Methylation of human microRNA genes in normal and neoplastic cells
-
Weber B, Stresemann C, Brueckner B, Lyko F. Methylation of human microRNA genes in normal and neoplastic cells. Cell Cycle 6(9), 1001-1005 (2007
-
(2007)
Cell Cycle
, vol.6
, Issue.9
, pp. 1001-1005
-
-
Weber, B.1
Stresemann, C.2
Brueckner, B.3
Lyko, F.4
-
96
-
-
0343621494
-
Aberrant CpG-island methylation has non
-
random and tumour-typespecific patterns
-
Costello JF, Frühwald MC, Smiraglia DJ et al. Aberrant CpG-island methylation has non-random and tumour-typespecific patterns. Nat. Genet. 24, 132-138 (2000
-
(2000)
Nat. Genet
, vol.24
, pp. 132-138
-
-
Costello, J.F.1
Frühwald, M.C.2
Smiraglia, D.J.3
-
97
-
-
31744433660
-
Evidence for an instructive mechanism of de novo methylation in cancer cells
-
Keshet I, Schlesinger Y, Farkash S et al. Evidence for an instructive mechanism of de novo methylation in cancer cells. Nat. Genet. 38, 149-153 (2006
-
(2006)
Nat. Genet
, vol.38
, pp. 149-153
-
-
Keshet, I.1
Schlesinger, Y.2
Farkash, S.3
-
98
-
-
82755161786
-
Epigenetic regulation of microRNAs in cancer: An integrated review of literature
-
Kunej T, Godnic I, Ferdin J, Horvat S, Dovc P, Calin GA. Epigenetic regulation of microRNAs in cancer: an integrated review of literature. Mutat. Res. 717, 77-84 (2011
-
(2011)
Mutat. Res
, vol.717
, pp. 77-84
-
-
Kunej, T.1
Godnic, I.2
Ferdin, J.3
Horvat, S.4
Dovc, P.5
Calin, G.A.6
-
99
-
-
33744805399
-
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
-
Saito Y, Liang G, Egger G et al. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9, 435-443 (2006
-
(2006)
Cancer Cell
, vol.9
, pp. 435-443
-
-
Saito, Y.1
Liang, G.2
Egger, G.3
-
100
-
-
44349124725
-
Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer
-
Zhang L, Volinia S, Bonome T et al. Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer. Proc. Natl Acad. Sci. USA 105, 7004-7009 (2008
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 7004-7009
-
-
Zhang, L.1
Volinia, S.2
Bonome, T.3
-
101
-
-
32944462300
-
Rapid alteration of microRNA levels by histone deacetylase inhibition
-
Scott GK, Mattie MD, Berger CE, Benz SC, Benz CC. Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res. 66, 1277-1281 (2006
-
(2006)
Cancer Res
, vol.66
, pp. 1277-1281
-
-
Scott, G.K.1
Mattie, M.D.2
Berger, C.E.3
Benz, S.C.4
Benz, C.C.5
-
102
-
-
51049119231
-
Diagnostic and prognostic microRNAs in stage II colon cancer
-
Schepeler T, Reinert JT, Ostenfeld MS et al. Diagnostic and prognostic microRNAs in stage II colon cancer. Cancer Res. 68, 6416-6424 (2008
-
(2008)
Cancer Res
, vol.68
, pp. 6416-6424
-
-
Schepeler, T.1
Reinert, J.T.2
Ostenfeld, M.S.3
-
103
-
-
42249089850
-
MicroRNA gene expression profile of hepatitis C virus-associated hepatocellular carcinoma
-
Varnholt H, Drebber U, Schulze F et al. MicroRNA gene expression profile of hepatitis C virus-associated hepatocellular carcinoma. Hepatology 47, 1223-1232 (2008
-
(2008)
Hepatology
, vol.47
, pp. 1223-1232
-
-
Varnholt, H.1
Drebber, U.2
Schulze, F.3
-
104
-
-
84875372911
-
Natural RNA circles function as efficient microRNA sponges
-
Hansen TB, Jensen TI, Clausen BH et al. Natural RNA circles function as efficient microRNA sponges. Nature 495, 384-388 (2013
-
(2013)
Nature
, vol.495
, pp. 384-388
-
-
Hansen, T.B.1
Jensen, T.I.2
Clausen, B.H.3
-
105
-
-
77953957633
-
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
-
Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 465, 1033-1038 (2010
-
(2010)
Nature
, vol.465
, pp. 1033-1038
-
-
Poliseno, L.1
Salmena, L.2
Zhang, J.3
Carver, B.4
Haveman, W.J.5
Pandolfi, P.P.6
-
106
-
-
84881503516
-
Pseudogene OCT4-pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for miR?145 in hepatocellular carcinoma
-
Wang L, Guo Z-Y, Zhang R et al. Pseudogene OCT4-pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for miR?145 in hepatocellular carcinoma. Carcinogenesis 34, 1773-1781 (2013
-
(2013)
Carcinogenesis
, vol.34
, pp. 1773-1781
-
-
Wang, L.1
Guo, Z.-Y.2
Zhang, R.3
-
107
-
-
84868106545
-
MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer
-
Wang Y, Zheng X, Zhang Z et al. MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer. PLoS ONE 7(10), e41693 (2012
-
(2012)
PLoS ONE
, vol.7
, Issue.10
, pp. e41693
-
-
Wang, Y.1
Zheng, X.2
Zhang, Z.3
-
108
-
-
84878650763
-
MiR?149 inhibits non-smallcell lung cancer cells EMT by targeting FOXM1
-
Ke Y, Zhao W, Xiong J, Cao R. miR?149 inhibits non-smallcell lung cancer cells EMT by targeting FOXM1. Biochem. Res. Int. 2013, 506731 (2013
-
(2013)
Biochem. Res. Int
, vol.2013
, pp. 506731
-
-
Ke, Y.1
Zhao, W.2
Xiong, J.3
Cao, R.4
-
109
-
-
79952783987
-
MicroRNAs as therapeutic targets in cancer
-
Nana-Sinkam SP, Croce CM. MicroRNAs as therapeutic targets in cancer. Transl. Res. 157, 216-225 (2011
-
(2011)
Transl. Res
, vol.157
, pp. 216-225
-
-
Nana-Sinkam, S.P.1
Croce, C.M.2
-
110
-
-
84869866890
-
MicroRNA and cancer
-
Jansson MD, Lund AH. MicroRNA and cancer. Mol. Oncol. 6(6), 590-610 (2012
-
(2012)
Mol. Oncol
, vol.6
, Issue.6
, pp. 590-610
-
-
Jansson, M.D.1
Lund, A.H.2
-
111
-
-
84887101163
-
MicroRNAs and other noncoding RNAs as targets for anticancer drug development
-
Ling H, Fabbri M, Calin GA. MicroRNAs and other noncoding RNAs as targets for anticancer drug development. Nat. Rev. Drug Discov. 12(11), 847-865 (2013
-
(2013)
Nat. Rev. Drug Discov
, vol.12
, Issue.11
, pp. 847-865
-
-
Ling, H.1
Fabbri, M.2
Calin, G.A.3
-
112
-
-
80052102044
-
Diabetes complications: The microRNA perspective
-
Kantharidis P, Wang B, Carew RM, Lan HY. Diabetes complications: The microRNA perspective. Diabetes 60(7), 1832-1837 (2011
-
(2011)
Diabetes
, vol.60
, Issue.7
, pp. 1832-1837
-
-
Kantharidis, P.1
Wang, B.2
Carew, R.M.3
Lan, H.Y.4
-
113
-
-
84900797916
-
MicroRNA-7a regulates pancreatic cell function
-
Latreille M, Hausser J, Stützer I et al. MicroRNA-7a regulates pancreatic ? cell function. J. Clin. Invest. 124(6), 2722-2735 (2014
-
(2014)
J. Clin. Invest
, vol.124
, Issue.6
, pp. 2722-2735
-
-
Latreille, M.1
Hausser, J.2
Stützer, I.3
-
114
-
-
84868475728
-
MicroRNA therapeutics for cardiovascular disease: Opportunities and obstacles
-
van Rooij E, Olson EN. MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles. Nat. Rev. Drug Discov. 11(11), 860-872 (2012
-
(2012)
Nat. Rev. Drug Discov
, vol.11
, Issue.11
, pp. 860-872
-
-
Van Rooij, E.1
Olson, E.N.2
-
115
-
-
84859500144
-
MicroRNA dysregulation in schizophrenia
-
Beveridge NJ, Cairns MJ. MicroRNA dysregulation in schizophrenia. Neurobiol. Dis. 46(2), 263-271 (2012
-
(2012)
Neurobiol. Dis
, vol.46
, Issue.2
, pp. 263-271
-
-
Beveridge, N.J.1
Cairns, M.J.2
-
116
-
-
84880956260
-
A blood based 12-miRNA signature of Alzheimer disease patients
-
Leidinger P, Backes C, Deutscher S et al. A blood based 12-miRNA signature of Alzheimer disease patients. Genome Biol. 14(7), R78 (2013
-
(2013)
Genome Biol
, vol.14
, Issue.7
, pp. R78
-
-
Leidinger, P.1
Backes, C.2
Deutscher, S.3
-
117
-
-
79956032718
-
Hsa-miR?34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease
-
Gaughwin PM, Ciesla M, Lahiri N, Tabrizi SJ, Brundin P, Björkqvist M. Hsa-miR?34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease. Hum. Mol. Genet. 20(11), 2225-2237 (2011
-
(2011)
Hum. Mol. Genet
, vol.20
, Issue.11
, pp. 2225-2237
-
-
Gaughwin, P.M.1
Ciesla, M.2
Lahiri, N.3
Tabrizi, S.J.4
Brundin, P.5
Björkqvist, M.6
-
118
-
-
84881245624
-
Circulating MicroRNAs as biomarkers for disease staging in multiple sclerosis
-
Gandhi R, Healy B, Gholipour T et al. Circulating MicroRNAs as biomarkers for disease staging in multiple sclerosis. Ann. Neurol. 73(6), 729-740 (2013
-
(2013)
Ann. Neurol
, vol.73
, Issue.6
, pp. 729-740
-
-
Gandhi, R.1
Healy, B.2
Gholipour, T.3
-
120
-
-
83255194160
-
Chemical modification and design of anti-miRNA oligonucleotides
-
Lennox KA, Behlke MA. Chemical modification and design of anti-miRNA oligonucleotides. Gene Ther. 18(12), 1111-1120 (2011
-
(2011)
Gene Ther
, vol.18
, Issue.12
, pp. 1111-1120
-
-
Lennox, K.A.1
Behlke, M.A.2
-
121
-
-
84892919070
-
Methods to enable the design of bioactive small molecules targeting RNA
-
Disney MD, Yildirim I, Childs-Disney JL. Methods to enable the design of bioactive small molecules targeting RNA. Org. Biomol. Chem. 12(7), 1029-1039 (2014
-
(2014)
Org. Biomol. Chem
, vol.12
, Issue.7
, pp. 1029-1039
-
-
Disney, M.D.1
Yildirim, I.2
Childs-Disney, J.L.3
-
122
-
-
66349108231
-
A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
-
Bramsen JB, Laursen MB, Nielsen AF et al. A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity. Nucleic Acids Res. 37(9), 2867-2881 (2009
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.9
, pp. 2867-2881
-
-
Bramsen, J.B.1
Laursen, M.B.2
Nielsen, A.F.3
-
124
-
-
0036294527
-
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
-
Zeng Y, Wagner E, Cullen B. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell 9, 1327-1333 (2002
-
(2002)
Mol. Cell
, vol.9
, pp. 1327-1333
-
-
Zeng, Y.1
Wagner, E.2
Cullen, B.3
-
125
-
-
12844285548
-
Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs
-
Yi R, Doehle B, Qin Y. Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs. RNA 11( 2), 220-226 (2005
-
(2005)
RNA
, vol.11
, Issue.2
, pp. 220-226
-
-
Yi, R.1
Doehle, B.2
Qin, Y.3
-
126
-
-
84868361171
-
Arresting the culprit: Targeted antagomir delivery to sequester oncogenic miR?221 in HCC
-
Kasinski AL, Slack FJ. Arresting the culprit: Targeted antagomir delivery to sequester oncogenic miR?221 in HCC. Mol. Ther. Nucleic Acids 1, e12 (2012
-
(2012)
Mol. Ther. Nucleic Acids
, vol.1
, pp. e12
-
-
Kasinski, A.L.1
Slack, F.J.2
-
127
-
-
0035962892
-
A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H
-
Zamaratski E, Pradeepkumar PI, Chattopadhyaya J. A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H. J. Biochem. Biophys. Methods 48(3), 189-208 (2001
-
(2001)
J. Biochem. Biophys. Methods
, vol.48
, Issue.3
, pp. 189-208
-
-
Zamaratski, E.1
Pradeepkumar, P.I.2
Chattopadhyaya, J.3
-
128
-
-
79953202455
-
Silencing of microRNA families by seed-targeting tiny LNAs
-
Obad S, dos Santos CO, Petri A et al. Silencing of microRNA families by seed-targeting tiny LNAs. Nat. Genet. 43(4), 371-378 (2011
-
(2011)
Nat. Genet
, vol.43
, Issue.4
, pp. 371-378
-
-
Obad, S.1
Dos Santos, C.O.2
Petri, A.3
-
129
-
-
0035113736
-
Locked nucleic acid (LNA): Finetuning the recognition of DNA and RNA
-
Braasch DA, Corey DR. Locked nucleic acid (LNA): finetuning the recognition of DNA and RNA. Chem. Biol. 8(1), 1-7 (2001
-
(2001)
Chem. Biol
, vol.8
, Issue.1
, pp. 1-7
-
-
Braasch, D.A.1
Corey, D.R.2
-
130
-
-
74049124186
-
Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
-
Jackson AL, Linsley PS. Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application. Nat. Rev. Drug Discov. 9(1), 57-67 (2010
-
(2010)
Nat. Rev. Drug Discov
, vol.9
, Issue.1
, pp. 57-67
-
-
Jackson, A.L.1
Linsley, P.S.2
-
131
-
-
0034015113
-
Phosphorothioate oligodeoxynucleotides: What is their origin and what is unique about them?
-
Eckstein F. Phosphorothioate oligodeoxynucleotides: what is their origin and what is unique about them?. Antisense Nucleic Acid Drug Dev. 10(2), 117-121 (2000
-
(2000)
Antisense Nucleic Acid Drug Dev
, vol.10
, Issue.2
, pp. 117-121
-
-
Eckstein, F.1
-
132
-
-
28444469246
-
Silencing of microRNAs in vivo with 'antagomirs'
-
Krutzfeldt J, Rajewsky N, Braich R et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 438(7068), 685-689 (2005
-
(2005)
Nature
, vol.438
, Issue.7068
, pp. 685-689
-
-
Krutzfeldt, J.1
Rajewsky, N.2
Braich, R.3
-
133
-
-
38649105459
-
Gait MJ. MiR?122 targeting with LNA/2'-Omethyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA-peptide conjugates
-
Fabani MM, Gait MJ. miR?122 targeting with LNA/2'-Omethyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA-peptide conjugates. RNA 14(2), 336-346 (2008
-
(2008)
RNA
, vol.14
, Issue.2
, pp. 336-346
-
-
Fabani, M.M.1
-
134
-
-
79251581020
-
The art of microRNA research
-
van Rooij E. The art of microRNA research. Circ. Res. 108(2), 219-234 (2011
-
(2011)
Circ. Res
, vol.108
, Issue.2
, pp. 219-234
-
-
Van Rooij, E.1
-
135
-
-
84891498808
-
Antagomirs and microRNA in status epilepticus
-
Henshall DC. Antagomirs and microRNA in status epilepticus. Epilepsia 54, 17-19 (2013
-
(2013)
Epilepsia
, vol.54
, pp. 17-19
-
-
Henshall, D.C.1
-
136
-
-
79960595150
-
MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis
-
Kurowska-Stolarska M, Alivernini S, Ballantine LE et al. MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proc. Natl Acad. Sci. USA 108(27), 11193-11198 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.27
, pp. 11193-11198
-
-
Kurowska-Stolarska, M.1
Alivernini, S.2
Ballantine, L.E.3
-
137
-
-
80053897836
-
Silencing of microRNA?21 in vivo ameliorates autoimmune splenomegaly in lupus mice
-
Garchow BG, Bartulos Encinas O, Leung YT et al. Silencing of microRNA?21 in vivo ameliorates autoimmune splenomegaly in lupus mice. EMBO Mol. Med. 3(10), 605-615 (2011
-
(2011)
EMBO Mol. Med
, vol.3
, Issue.10
, pp. 605-615
-
-
Garchow, B.G.1
Bartulos Encinas, O.2
Leung, Y.T.3
-
138
-
-
79960015327
-
Antagonism of miR?33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
-
Rayner KJ, Sheedy FJ, Esau CC et al. Antagonism of miR?33 in mice promotes reverse cholesterol transport and regression of atherosclerosis. J. Clin. Invest. 121(7), 2921-2931 (2011
-
(2011)
J. Clin. Invest
, vol.121
, Issue.7
, pp. 2921-2931
-
-
Rayner, K.J.1
Sheedy, F.J.2
Esau, C.C.3
-
139
-
-
84857683479
-
An antagomir to microRNA Let7f promotes neuroprotection in an ischemic stroke model
-
Selvamani A, Sathyan P, Miranda RC, Sohrabji F. An antagomir to microRNA Let7f promotes neuroprotection in an ischemic stroke model. PLoS ONE 7(2), e32662 (2012
-
(2012)
PLoS ONE
, vol.7
, Issue.2
, pp. e32662
-
-
Selvamani, A.1
Sathyan, P.2
Miranda, R.C.3
Sohrabji, F.4
-
140
-
-
78149303249
-
MicroRNA sponges: Progress and possibilities
-
Ebert MS, Sharp PA. MicroRNA sponges: progress and possibilities. RNA 16(11), 2043-2050 (2010
-
(2010)
RNA
, vol.16
, Issue.11
, pp. 2043-2050
-
-
Ebert, M.S.1
Sharp, P.A.2
-
141
-
-
54749089002
-
Small-molecule inhibitors of microRNA miR?21 function
-
Gumireddy K, Young DD, Xiong X, Hogenesch JB, Huang Q, Deiters A. Small-molecule inhibitors of microRNA miR?21 function. Angew. Chem. Int. Ed. Engl. 47(39), 7482-7484 (2008
-
(2008)
Angew. Chem. Int. Ed. Engl
, vol.47
, Issue.39
, pp. 7482-7484
-
-
Gumireddy, K.1
Young, D.D.2
Xiong, X.3
Hogenesch, J.B.4
Huang, Q.5
Deiters, A.6
-
142
-
-
77449141681
-
Small molecule modifiers of the microRNA and RNA interference pathway
-
Deiters A. Small molecule modifiers of the microRNA and RNA interference pathway. AAPS J. 12(1), 51-60 (2010
-
(2010)
AAPS J.
, vol.12
, Issue.1
, pp. 51-60
-
-
Deiters, A.1
-
143
-
-
84897024057
-
Sequence-based design of bioactive small molecules that target precursor microRNAs
-
Velagapudi SP, Gallo SM, Disney MD. Sequence-based design of bioactive small molecules that target precursor microRNAs. Nat. Chem. Biol. 10(4), 291-297 (2014
-
(2014)
Nat. Chem. Biol
, vol.10
, Issue.4
, pp. 291-297
-
-
Velagapudi, S.P.1
Gallo, S.M.2
Disney, M.D.3
-
144
-
-
77953312157
-
Small molecule modifiers of microRNA miR?122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma
-
Young DD, Connelly CM, Grohmann C, Deiters A. Small molecule modifiers of microRNA miR?122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. J. Am. Chem. Soc. 132(23), 7976-7981 (2010
-
(2010)
J. Am. Chem. Soc
, vol.132
, Issue.23
, pp. 7976-7981
-
-
Young, D.D.1
Connelly, C.M.2
Grohmann, C.3
Deiters, A.4
-
145
-
-
84894488215
-
Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor
-
Velagapudi SP, Disney MD. Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor. Chem. Commun. (Camb) 50(23), 3027-3029 (2014
-
(2014)
Chem. Commun. (Camb
, vol.50
, Issue.23
, pp. 3027-3029
-
-
Velagapudi, S.P.1
Disney, M.D.2
-
146
-
-
53349168896
-
Enhancement of RNAi by a small molecule antibiotic enoxacin
-
Zhang Q, Zhang C, Xi Z. Enhancement of RNAi by a small molecule antibiotic enoxacin. Cell Res. 18(10), 1077-1079 (2008
-
(2008)
Cell Res
, vol.18
, Issue.10
, pp. 1077-1079
-
-
Zhang, Q.1
Zhang, C.2
Xi, Z.3
-
147
-
-
79952717616
-
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
-
Melo S, Villanueva A, Moutinho C et al. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proc. Natl Acad. Sci. USA, 108(11), 4394-4399 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.11
, pp. 4394-4399
-
-
Melo, S.1
Villanueva, A.2
Moutinho, C.3
-
148
-
-
84895522921
-
Enoxacin elevates microRNA levels in rat frontal cortex and prevents learned helplessness
-
Smalheiser NR, Zhang H, Dwivedi Y. Enoxacin elevates microRNA levels in rat frontal cortex and prevents learned helplessness. Front. Psychiatry 5, 6 (2014
-
(2014)
Front. Psychiatry
, vol.5
, Issue.6
-
-
Smalheiser, N.R.1
Zhang, H.2
Dwivedi, Y.3
-
149
-
-
66449136951
-
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
-
Kota J, Chivukula RR, O'Donnell KA et al. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137(6), 1005-1017 (2009
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O'donnell, K.A.3
-
150
-
-
84861902017
-
Lipid-based nanoparticle delivery of Pre-miR?107 inhibits the tumorigenicity of head and neck squamous cell carcinoma
-
Piao L, Zhang M, Datta J et al. Lipid-based nanoparticle delivery of Pre-miR?107 inhibits the tumorigenicity of head and neck squamous cell carcinoma. Mol. Ther. 20(6), 1261-1269 (2012
-
(2012)
Mol. Ther
, vol.20
, Issue.6
, pp. 1261-1269
-
-
Piao, L.1
Zhang, M.2
Datta, J.3
-
151
-
-
84886415287
-
Cationic lipid nanoparticles for therapeutic delivery of siRNA and miRNA to murine liver tumor
-
Hsu S-H, Yu B, Wang X et al. Cationic lipid nanoparticles for therapeutic delivery of siRNA and miRNA to murine liver tumor. Nanomed. Nanotechnol. 9(8), 1169-1180 (2013
-
(2013)
Nanomed. Nanotechnol
, vol.9
, Issue.8
, pp. 1169-1180
-
-
Hsu, S.-H.1
Yu, B.2
Wang, X.3
-
152
-
-
43049176170
-
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
-
Akinc A, Zumbuehl A, Goldberg M et al. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat. Biotechnol. 26(5), 561-569 (2008
-
(2008)
Nat. Biotechnol
, vol.26
, Issue.5
, pp. 561-569
-
-
Akinc, A.1
Zumbuehl, A.2
Goldberg, M.3
-
154
-
-
79961043075
-
MicroRNA delivery by cationic lipoplexes for lung cancer therapy
-
Wu Y, Crawford M, Yu B, Mao Y, Nana-Sinkam SP, Lee LJ. MicroRNA delivery by cationic lipoplexes for lung cancer therapy. Mol. Pharm. 8(4), 1381-1389 (2011
-
(2011)
Mol. Pharm
, vol.8
, Issue.4
, pp. 1381-1389
-
-
Wu, Y.1
Crawford, M.2
Yu, B.3
Mao, Y.4
Nana-Sinkam, S.P.5
Lee, L.J.6
-
155
-
-
84878858306
-
Therapeutic delivery of microRNA-29b by cationic lipoplexes for lung cancer
-
Wu Y, Crawford M, Mao Y et al. Therapeutic delivery of microRNA-29b by cationic lipoplexes for lung cancer. Mol. Ther. Nucleic Acids 2, e84 (2013
-
(2013)
Mol. Ther. Nucleic Acids
, vol.2
, pp. e84
-
-
Wu, Y.1
Crawford, M.2
Mao, Y.3
-
156
-
-
84875740719
-
Systemic delivery of microRNA-34a for cancer stem cell therapy
-
Shi S, Han L, Gong T, Zhang Z, Sun X. Systemic delivery of microRNA-34a for cancer stem cell therapy. Angew. Chem. Int. Ed. Engl. 52(14), 3901-3905 (2013
-
(2013)
Angew. Chem. Int. Ed. Engl
, vol.52
, Issue.14
, pp. 3901-3905
-
-
Shi, S.1
Han, L.2
Gong, T.3
Zhang, Z.4
Sun, X.5
-
157
-
-
77956269093
-
Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy
-
Chen Y, Zhu X, Zhang X, Liu B, Huang L. Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy. Mol. Ther. 18(9), 1650-1656 (2010
-
(2010)
Mol. Ther
, vol.18
, Issue.9
, pp. 1650-1656
-
-
Chen, Y.1
Zhu, X.2
Zhang, X.3
Liu, B.4
Huang, L.5
-
158
-
-
79957900919
-
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice
-
Trang P, Wiggins JF, Daige CL et al. Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice. Mol. Ther. 19(6), 1116-1122 (2011
-
(2011)
Mol. Ther
, vol.19
, Issue.6
, pp. 1116-1122
-
-
Trang, P.1
Wiggins, J.F.2
Daige, C.L.3
-
159
-
-
36049042009
-
Sticky overhangs enhance siRNA-mediated gene silencing
-
Bolcato-Bellemin A-L, Bonnet M-E, Creusat G, Erbacher P, Behr JP. Sticky overhangs enhance siRNA-mediated gene silencing. Proc. Natl Acad. Sci. USA 104(41), 16050-16055 (2007
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, Issue.41
, pp. 16050-16055
-
-
Bolcato-Bellemin, A.-L.1
Bonnet, M.-E.2
Creusat, G.3
Erbacher, P.4
Behr, J.P.5
-
160
-
-
84863229706
-
Efficient delivery of sticky siRNA and potent gene silencing in a prostate cancer model using a generation 5 triethanolamine-core PAMAM dendrimer
-
Liu X, Liu C, Laurini E et al. Efficient delivery of sticky siRNA and potent gene silencing in a prostate cancer model using a generation 5 triethanolamine-core PAMAM dendrimer. Mol. Pharm. 9(3), 470-481 (2011
-
(2011)
Mol. Pharm
, vol.9
, Issue.3
, pp. 470-481
-
-
Liu, X.1
Liu, C.2
Laurini, E.3
-
161
-
-
84862808036
-
Cationic polyurethanes-short branch PEI-mediated delivery of Mir145 inhibited epithelial-mesenchymal transdifferentiation and cancer stem-like properties and in lung adenocarcinoma
-
Chiou GY, Cherng JY, Hsu HS et al. Cationic polyurethanes-short branch PEI-mediated delivery of Mir145 inhibited epithelial-mesenchymal transdifferentiation and cancer stem-like properties and in lung adenocarcinoma. J. Control. Release 159(2), 240-250 (2012
-
(2012)
J. Control. Release
, vol.159
, Issue.2
, pp. 240-250
-
-
Chiou, G.Y.1
Cherng, J.Y.2
Hsu, H.S.3
-
162
-
-
83355166283
-
Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI
-
Yang YP, Chien Y, Chiou GY et al. Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI. Biomaterials 33(5), 1462-1476 (2012
-
(2012)
Biomaterials
, vol.33
, Issue.5
, pp. 1462-1476
-
-
Yang, Y.P.1
Chien, Y.2
Chiou, G.Y.3
-
163
-
-
79955774513
-
A brain-targeted rabies virus glycoprotein-disulfide linked PEI nanocarrier for delivery of neurogenic microRNA
-
Hwang do W, Son S, Jang J et al. A brain-targeted rabies virus glycoprotein-disulfide linked PEI nanocarrier for delivery of neurogenic microRNA. Biomaterials 32(21), 4968-4975 (2011
-
(2011)
Biomaterials
, vol.32
, Issue.21
, pp. 4968-4975
-
-
-
164
-
-
68549104191
-
Nanotechnologies and controlled release systems for the delivery of antisense oligonucleotides and small interfering RNA
-
Fattal E, Barratt G. Nanotechnologies and controlled release systems for the delivery of antisense oligonucleotides and small interfering RNA. Br. J. Pharmacol. 157(2), 179-194 (2009
-
(2009)
Br. J. Pharmacol
, vol.157
, Issue.2
, pp. 179-194
-
-
Fattal, E.1
Barratt, G.2
-
165
-
-
84862993281
-
Nanoparticle-based therapy in an in vivo microRNA-155 (miR?155)-dependent mouse model of lymphoma
-
Babar IA, Cheng CJ, Booth CJ et al. Nanoparticle-based therapy in an in vivo microRNA-155 (miR?155)-dependent mouse model of lymphoma. Proc. Natl Acad. Sci. USA 109(26), e1695-e1704 (2012
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, Issue.26
, pp. e1695-e1704
-
-
Babar, I.A.1
Cheng, C.J.2
Booth, C.J.3
-
166
-
-
84860720576
-
Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing
-
Cheng CJ, Saltzman WM. Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing. Mol. Pharm. 9(5), 1481-1488 (2012
-
(2012)
Mol. Pharm
, vol.9
, Issue.5
, pp. 1481-1488
-
-
Cheng, C.J.1
Saltzman, W.M.2
-
167
-
-
84861473531
-
Inhibition of neuroblastoma tumor growth by targeted delivery of microRNA-34a using anti-disialoganglioside GD2 coated nanoparticles
-
Tivnan A, Orr WS, Gubala V et al. Inhibition of neuroblastoma tumor growth by targeted delivery of microRNA-34a using anti-disialoganglioside GD2 coated nanoparticles. PLoS ONE 7(5), e38129 (2012
-
(2012)
PLoS ONE
, vol.7
, Issue.5
, pp. e38129
-
-
Tivnan, A.1
Orr, W.S.2
Gubala, V.3
-
168
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
Soutschek J, Akinc A, Bramlage B et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 432(7014), 173-178 (2004
-
(2004)
Nature
, vol.432
, Issue.7014
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
-
170
-
-
84862908547
-
Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
-
Montecalvo A, Larregina AT, Shufesky WJ et al. Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood 119(3), 756-766 (2012
-
(2012)
Blood
, vol.119
, Issue.3
, pp. 756-766
-
-
Montecalvo, A.1
Larregina, A.T.2
Shufesky, W.J.3
-
171
-
-
84893577906
-
A paradigm shift for extracellular vesicles as small RNA carriers: From cellular waste elimination to therapeutic applications
-
Hagiwara K, Ochiya T, Kosaka N. A paradigm shift for extracellular vesicles as small RNA carriers: from cellular waste elimination to therapeutic applications. Drug Deliv. Transl. Res. 4, 31-37 (2014
-
(2014)
Drug Deliv. Transl. Res
, vol.4
, pp. 31-37
-
-
Hagiwara, K.1
Ochiya, T.2
Kosaka, N.3
-
172
-
-
79953858598
-
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
-
Alvarez-Erviti L, Seow Y, Yin H, Betts C, Lakhal S, Wood MJ. Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes. Nat. Biotechnol. 29(4), 341-345 (2011
-
(2011)
Nat. Biotechnol
, vol.29
, Issue.4
, pp. 341-345
-
-
Alvarez-Erviti, L.1
Seow, Y.2
Yin, H.3
Betts, C.4
Lakhal, S.5
Wood, M.J.6
-
173
-
-
84871923602
-
Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells
-
Ohno SI, Takanashi M, Sudo K et al. Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells. Mol. Ther. 21(1), 185-191 (2013
-
(2013)
Mol. Ther
, vol.21
, Issue.1
, pp. 185-191
-
-
Ohno, S.I.1
Takanashi, M.2
Sudo, K.3
-
174
-
-
84862785747
-
Development of a microRNA delivery system based on bacteriophage MS2 virus-like particles
-
Pan Y, Zhang Y, Jia T, Zhang K, Li J, Wang L. Development of a microRNA delivery system based on bacteriophage MS2 virus-like particles. FEBS J. 279(7), 1198-1208 (2012
-
(2012)
FEBS J.
, vol.279
, Issue.7
, pp. 1198-1208
-
-
Pan, Y.1
Zhang, Y.2
Jia, T.3
Zhang, K.4
Li, J.5
Wang, L.6
-
175
-
-
79958858482
-
Targeted delivery of mutant tolerant anti-coxsackievirus artificial microRNAs using folate conjugated bacteriophage Phi29 pRNA
-
Ye X, Liu Z, Hemida MG, Yang D. Targeted delivery of mutant tolerant anti-coxsackievirus artificial microRNAs using folate conjugated bacteriophage Phi29 pRNA. PLoS ONE 6(6), e21215 (2011
-
(2011)
PLoS ONE
, vol.6
, Issue.6
, pp. e21215
-
-
Ye, X.1
Liu, Z.2
Hemida, M.G.3
Yang, D.4
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