메뉴 건너뛰기




Volumn 14, Issue 7, 2013, Pages

A blood based 12-miRNA signature of Alzheimer disease patients

Author keywords

Alzheimer disease; Biomarker; miRNA; Next generation sequencing; Quantitative real time PCR

Indexed keywords

BRAIN MIR 112; BRAIN MIR 161; HSA LET 7D 3P; HSA LET 7F 5P; HSA MIR 103A 3P; HSA MIR 1285 5P; HSA MIR 151A 3P; HSA MIR 26A 5P; HSA MIR 26B 5P; HSA MIR 5010 3P; HSA MIR 532 5P; MICRORNA; MICRORNA 107; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

EID: 84880956260     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2013-14-7-r78     Document Type: Article
Times cited : (401)

References (72)
  • 2
    • 0031695197 scopus 로고    scopus 로고
    • Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
    • Brookmeyer R, Gray S, Kawas C: Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. Am J Public Health 1998, 88:1337-1342.
    • (1998) Am J Public Health , vol.88 , pp. 1337-1342
    • Brookmeyer, R.1    Gray, S.2    Kawas, C.3
  • 3
    • 79960347757 scopus 로고    scopus 로고
    • Perspective: prevention is better than cure
    • Gandy S: Perspective: prevention is better than cure. Nature 2011, 475: S15.
    • (2011) Nature , vol.475
    • Gandy, S.1
  • 4
    • 84923857119 scopus 로고    scopus 로고
    • Deutsche Gesellschaft für Psychiatrie PuND, (DGN) DGfrN: S3-Leitlinie "Demenzen" 2009.
    • Deutsche Gesellschaft für Psychiatrie PuND, (DGN) DGfrN: S3-Leitlinie "Demenzen" 2009.
  • 6
    • 52049090426 scopus 로고    scopus 로고
    • Amyloid beta protein and tau in cerebrospinal fluid and plasma as biomarkers for dementia: a review of recent literature
    • Frankfort SV, Tulner LR, van Campen JP, Verbeek MM, Jansen RW, Beijnen JH: Amyloid beta protein and tau in cerebrospinal fluid and plasma as biomarkers for dementia: a review of recent literature. Curr Clin Pharmacol 2008, 3:123-131.
    • (2008) Curr Clin Pharmacol , vol.3 , pp. 123-131
    • Frankfort, S.V.1    Tulner, L.R.2    van Campen, J.P.3    Verbeek, M.M.4    Jansen, R.W.5    Beijnen, J.H.6
  • 7
    • 68149160101 scopus 로고    scopus 로고
    • [Biomarkers for early diagnosis of Alzheimer's disease: current update and future directions]
    • Malaplate-Armand C, Desbene C, Pillot T, Olivier JL: [Biomarkers for early diagnosis of Alzheimer's disease: current update and future directions]. Rev Neurol (Paris) 2009, 165:511-520.
    • (2009) Rev Neurol (Paris) , vol.165 , pp. 511-520
    • Malaplate-Armand, C.1    Desbene, C.2    Pillot, T.3    Olivier, J.L.4
  • 12
    • 84860494301 scopus 로고    scopus 로고
    • Combination of p53(ser15) and p21/p21 (thr145) in peripheral blood lymphocytes as potential Alzheimer's disease biomarkers
    • Tan M, Wang S, Song J, Jia J: Combination of p53(ser15) and p21/p21 (thr145) in peripheral blood lymphocytes as potential Alzheimer's disease biomarkers. Neurosci Lett 2012, 516:226-231.
    • (2012) Neurosci Lett , vol.516 , pp. 226-231
    • Tan, M.1    Wang, S.2    Song, J.3    Jia, J.4
  • 14
    • 34347376692 scopus 로고    scopus 로고
    • Characterization of microRNA expression profiles in normal human tissues
    • Liang Y, Ridzon D, Wong L, Chen C: Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 2007, 8:166.
    • (2007) BMC Genomics , vol.8 , pp. 166
    • Liang, Y.1    Ridzon, D.2    Wong, L.3    Chen, C.4
  • 16
    • 38749095507 scopus 로고    scopus 로고
    • The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1
    • Wang WX, Rajeev BW, Stromberg AJ, Ren N, Tang G, Huang Q, Rigoutsos I, Nelson PT: The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 2008, 28:1213-1223.
    • (2008) J Neurosci , vol.28 , pp. 1213-1223
    • Wang, W.X.1    Rajeev, B.W.2    Stromberg, A.J.3    Ren, N.4    Tang, G.5    Huang, Q.6    Rigoutsos, I.7    Nelson, P.T.8
  • 17
    • 80054025163 scopus 로고    scopus 로고
    • MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid beta, novel targets in sporadic Alzheimer's disease
    • Geekiyanage H, Chan C: MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid beta, novel targets in sporadic Alzheimer's disease. J Neurosci 2011, 31:14820-14830.
    • (2011) J Neurosci , vol.31 , pp. 14820-14830
    • Geekiyanage, H.1    Chan, C.2
  • 18
    • 79151483332 scopus 로고    scopus 로고
    • MicroRNA-101 downregulates Alzheimer's amyloidbeta precursor protein levels in human cell cultures and is differentially expressed
    • Long JM, Lahiri DK: MicroRNA-101 downregulates Alzheimer's amyloidbeta precursor protein levels in human cell cultures and is differentially expressed. Biochem Biophys Res Commun 2010, 404:889-895.
    • (2010) Biochem Biophys Res Commun , vol.404 , pp. 889-895
    • Long, J.M.1    Lahiri, D.K.2
  • 19
    • 84860369464 scopus 로고    scopus 로고
    • Blood serum miRNA: noninvasive biomarkers for Alzheimer's disease
    • Geekiyanage H, Jicha GA, Nelson PT, Chan C: Blood serum miRNA: noninvasive biomarkers for Alzheimer's disease. Exp Neurol 2011, 235:491-496.
    • (2011) Exp Neurol , vol.235 , pp. 491-496
    • Geekiyanage, H.1    Jicha, G.A.2    Nelson, P.T.3    Chan, C.4
  • 21
    • 84923857118 scopus 로고    scopus 로고
    • miRBase.
    • miRBase.
  • 22
    • 78651293534 scopus 로고    scopus 로고
    • miRBase: integrating microRNA annotation and deep-sequencing data
    • Kozomara A, Griffiths-Jones S: miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res 2010, 39:D152-157.
    • (2010) Nucleic Acids Res , vol.39 , pp. D152-D157
    • Kozomara, A.1    Griffiths-Jones, S.2
  • 23
    • 84923857117 scopus 로고    scopus 로고
    • TAM-tool for annotations of human miRNAs.
    • TAM-tool for annotations of human miRNAs. [http://202.38.126.151/hmdd/tools/tam.html].
  • 24
    • 77955286897 scopus 로고    scopus 로고
    • TAM: a method for enrichment and depletion analysis of a microRNA category in a list of microRNAs
    • Lu M, Shi B, Wang J, Cao Q, Cui Q: TAM: a method for enrichment and depletion analysis of a microRNA category in a list of microRNAs. BMC Bioinformatics 2010, 11:419.
    • (2010) BMC Bioinformatics , vol.11 , pp. 419
    • Lu, M.1    Shi, B.2    Wang, J.3    Cao, Q.4    Cui, Q.5
  • 29
    • 35148814074 scopus 로고    scopus 로고
    • Transcriptional profiling of Alzheimer blood mononuclear cells by microarray
    • Maes OC, Xu S, Yu B, Chertkow HM, Wang E, Schipper HM: Transcriptional profiling of Alzheimer blood mononuclear cells by microarray. Neurobiol Aging 2007, 28:1795-1809.
    • (2007) Neurobiol Aging , vol.28 , pp. 1795-1809
    • Maes, O.C.1    Xu, S.2    Yu, B.3    Chertkow, H.M.4    Wang, E.5    Schipper, H.M.6
  • 30
    • 77957265786 scopus 로고    scopus 로고
    • miR-106b aberrantly expressed in a double transgenic mouse model for Alzheimer's disease targets TGF-beta type II receptor
    • Wang H, Liu J, Zong Y, Xu Y, Deng W, Zhu H, Liu Y, Ma C, Huang L, Zhang L, Qin C: miR-106b aberrantly expressed in a double transgenic mouse model for Alzheimer's disease targets TGF-beta type II receptor. Brain Res 2010, 1357:166-174.
    • (2010) Brain Res , vol.1357 , pp. 166-174
    • Wang, H.1    Liu, J.2    Zong, Y.3    Xu, Y.4    Deng, W.5    Zhu, H.6    Liu, Y.7    Ma, C.8    Huang, L.9    Zhang, L.10    Qin, C.11
  • 32
    • 77952336221 scopus 로고    scopus 로고
    • Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3
    • Shioya M, Obayashi S, Tabunoki H, Arima K, Saito Y, Ishida T, Satoh J: Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3. Neuropathol Appl Neurobiol 2010, 36:320-330.
    • (2010) Neuropathol Appl Neurobiol , vol.36 , pp. 320-330
    • Shioya, M.1    Obayashi, S.2    Tabunoki, H.3    Arima, K.4    Saito, Y.5    Ishida, T.6    Satoh, J.7
  • 33
    • 80053477918 scopus 로고    scopus 로고
    • Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function
    • Delay C, Calon F, Mathews P, Hebert SS: Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function. Mol Neurodegener 2011, 6:70.
    • (2011) Mol Neurodegener , vol.6 , pp. 70
    • Delay, C.1    Calon, F.2    Mathews, P.3    Hebert, S.S.4
  • 35
    • 71349085957 scopus 로고    scopus 로고
    • Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling
    • Moloney AM, Griffin RJ, Timmons S, O'Connor R, Ravid R, O'Neill C: Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling. Neurobiol Aging 2010, 31:224-243.
    • (2010) Neurobiol Aging , vol.31 , pp. 224-243
    • Moloney, A.M.1    Griffin, R.J.2    Timmons, S.3    O'Connor, R.4    Ravid, R.5    O'Neill, C.6
  • 39
    • 84859918676 scopus 로고    scopus 로고
    • Cyclin D2 in the basal process of neural progenitors is linked to non-equivalent cell fates
    • Tsunekawa Y, Britto JM, Takahashi M, Polleux F, Tan SS, Osumi N: Cyclin D2 in the basal process of neural progenitors is linked to non-equivalent cell fates. EMBO J 2012, 31:1879-1892.
    • (2012) EMBO J , vol.31 , pp. 1879-1892
    • Tsunekawa, Y.1    Britto, J.M.2    Takahashi, M.3    Polleux, F.4    Tan, S.S.5    Osumi, N.6
  • 41
    • 84867832050 scopus 로고    scopus 로고
    • MicroRNAs as active players in the pathogenesis of multiple sclerosis
    • Fenoglio C, Ridolfi E, Galimberti D, Scarpini E: MicroRNAs as active players in the pathogenesis of multiple sclerosis. Int J Mol Sci 2012, 13:13227-13239.
    • (2012) Int J Mol Sci , vol.13 , pp. 13227-13239
    • Fenoglio, C.1    Ridolfi, E.2    Galimberti, D.3    Scarpini, E.4
  • 43
    • 84923857116 scopus 로고    scopus 로고
    • Human MiRNA & Disease Database.
  • 44
    • 77954996105 scopus 로고    scopus 로고
    • MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study
    • Nelson PT, Wang WX: MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study. J Alzheimers Dis 2010, 21:75-79.
    • (2010) J Alzheimers Dis , vol.21 , pp. 75-79
    • Nelson, P.T.1    Wang, W.X.2
  • 51
    • 77149132365 scopus 로고    scopus 로고
    • Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls
    • Keller A, Leidinger P, Lange J, Borries A, Schroers H, Scheffler M, Lenhof HP, Ruprecht K, Meese E: Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls. PLoS One 2009, 4:e7440.
    • (2009) PLoS One , vol.4
    • Keller, A.1    Leidinger, P.2    Lange, J.3    Borries, A.4    Schroers, H.5    Scheffler, M.6    Lenhof, H.P.7    Ruprecht, K.8    Meese, E.9
  • 52
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM: Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 53
    • 84923857115 scopus 로고    scopus 로고
    • FASTX-Toolkit. [http://hannonlab.cshl.edu/fastx_toolkit/].
  • 54
    • 84855293838 scopus 로고    scopus 로고
    • miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades
    • Friedländer MR, Mackowiak SD, Li N, Chen W, Rajewsky N: miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. Nucleic Acids Res 2012, 40:37-52.
    • (2012) Nucleic Acids Res , vol.40 , pp. 37-52
    • Friedländer, M.R.1    Mackowiak, S.D.2    Li, N.3    Chen, W.4    Rajewsky, N.5
  • 56
    • 78651293534 scopus 로고    scopus 로고
    • miRBase: integrating microRNA annotation and deep-sequencing data
    • Kozomara A, Griffiths-Jones S: miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res 2011, 39:D152-157.
    • (2011) Nucleic Acids Res , vol.39 , pp. D152-D157
    • Kozomara, A.1    Griffiths-Jones, S.2
  • 57
    • 33644875300 scopus 로고    scopus 로고
    • snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs
    • Lestrade L, Weber MJ: snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. Nucleic Acids Res 2006, 34:D158-162.
    • (2006) Nucleic Acids Res , vol.34 , pp. D158-D162
    • Lestrade, L.1    Weber, M.J.2
  • 58
    • 84923857114 scopus 로고    scopus 로고
    • Ensembl. [ftp://ftp.ensembl.org/pub/release-67/fasta/homo_sapiens/ncrna/].
  • 60
    • 84923857113 scopus 로고    scopus 로고
    • GEO Database. [http://www.ncbi.nlm.nih.gov/geo/].
  • 61
    • 0035829361 scopus 로고    scopus 로고
    • Controlling the false discovery rate in behavior genetics research
    • Benjamini Y, Drai D, Elmer G, Kafkafi N, Golani I: Controlling the false discovery rate in behavior genetics research. Behav Brain Res 2001, 125:279-284.
    • (2001) Behav Brain Res , vol.125 , pp. 279-284
    • Benjamini, Y.1    Drai, D.2    Elmer, G.3    Kafkafi, N.4    Golani, I.5
  • 62
    • 33645762226 scopus 로고
    • A sharper bonferroni procedure for multiple tests of significance
    • Hochberg Y: A sharper bonferroni procedure for multiple tests of significance. Biometrica 1988, 75:185-193.
    • (1988) Biometrica , vol.75 , pp. 185-193
    • Hochberg, Y.1
  • 63
    • 84923857112 scopus 로고    scopus 로고
    • Vienna: R Foundation for Statistical Computing 2008.
    • Team R: R: A Languageand Environment for Statistical Computing. Vienna: R Foundation for Statistical Computing 2008.
  • 64
    • 84923857111 scopus 로고    scopus 로고
    • miRDB. [http://mirdb.org/miRDB/].
  • 65
    • 44149083586 scopus 로고    scopus 로고
    • miRDB: a microRNA target prediction and functional annotation database with a wiki interface
    • Wang X: miRDB: a microRNA target prediction and functional annotation database with a wiki interface. RNA 2008, 14:1012-1017.
    • (2008) RNA , vol.14 , pp. 1012-1017
    • Wang, X.1
  • 66
    • 38849145861 scopus 로고    scopus 로고
    • Prediction of both conserved and nonconserved microRNA targets in animals
    • Wang X, El Naqa IM: Prediction of both conserved and nonconserved microRNA targets in animals. Bioinformatics 2008, 24:325-332.
    • (2008) Bioinformatics , vol.24 , pp. 325-332
    • Wang, X.1    El Naqa, I.M.2
  • 67
    • 84923857110 scopus 로고    scopus 로고
    • TargetScan. [http://www.targetscan.org/vert_50/seedmatch.html].
  • 68
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP: Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005, 120:15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 69
    • 84923857109 scopus 로고    scopus 로고
    • GeneTrail. [http://genetrail.bioinf.uni-sb.de/].
  • 71
    • 0001677717 scopus 로고
    • Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
    • Benjamini Y, Hochberg Y: Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing. J Roy Stat SocB 1995, 57:289-300.
    • (1995) J Roy Stat SocB , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.