Sequence-based design of bioactive small molecules that target precursor microRNAs

Nature Chemical Biology

Volumn 10, Issue 4, 2014, Pages 291-297

  Velagapudi, Sai Pradeep ^a,b   Gallo, Steven M ^b   Disney, Matthew D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZIMIDAZOLE; MESSENGER RNA; MICRORNA; MICRORNA 96; OLIGONUCLEOTIDE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; FOXO1 GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RNA SEQUENCE;

ANNEXIN A5; APOPTOSIS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DNA FINGERPRINTING; DNA, NEOPLASM; DRUG DESIGN; FORKHEAD TRANSCRIPTION FACTORS; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; IN SITU NICK-END LABELING; MICRORNAS; NUCLEASE PROTECTION ASSAYS; OLIGONUCLEOTIDES; POLYMERASE CHAIN REACTION; RIBONUCLEASE III; SMALL MOLECULE LIBRARIES; TRANSCRIPTION, GENETIC;

EID: 84897024057     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1452     Document Type: Article

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