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Volumn 6, Issue 6, 2012, Pages 590-610

MicroRNA and cancer

Author keywords

Cancer; MicroRNA; Non coding RNA; Therapy

Indexed keywords

ANTAGOMIR; ANTINEOPLASTIC AGENT; DICER; LOCKED NUCLEIC ACID; MICRORNA; MICRORNA 10B; MICRORNA 122; MICRORNA 26A; MICRORNA 9; MICRORNA INHIBITOR; PROTEIN P53; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84869866890     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2012.09.006     Document Type: Review
Times cited : (990)

References (237)
  • 1
    • 76749134307 scopus 로고    scopus 로고
    • Many families of C. elegans microRNAs are not essential for development or viability
    • Alvarez-Saavedra E., Horvitz H.R. Many families of C. elegans microRNAs are not essential for development or viability. Curr. Biol. 2010, 20:367-373.
    • (2010) Curr. Biol. , vol.20 , pp. 367-373
    • Alvarez-Saavedra, E.1    Horvitz, H.R.2
  • 2
    • 39949085583 scopus 로고    scopus 로고
    • Stress granules: the Tao of RNA triage
    • Anderson P., Kedersha N. Stress granules: the Tao of RNA triage. Trends Biochem. Sci. 2008, 33:141-150.
    • (2008) Trends Biochem. Sci. , vol.33 , pp. 141-150
    • Anderson, P.1    Kedersha, N.2
  • 5
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 8
    • 77956279586 scopus 로고    scopus 로고
    • The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex
    • Boominathan L. The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex. PLoS One 2010, 5:e10615.
    • (2010) PLoS One , vol.5
    • Boominathan, L.1
  • 10
    • 54049084380 scopus 로고    scopus 로고
    • A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
    • Bracken C.P., Gregory P.A., Kolesnikoff N., Bert A.G., Wang J., Shannon M.F., Goodall G.J. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res. 2008, 68:7846-7854.
    • (2008) Cancer Res. , vol.68 , pp. 7846-7854
    • Bracken, C.P.1    Gregory, P.A.2    Kolesnikoff, N.3    Bert, A.G.4    Wang, J.5    Shannon, M.F.6    Goodall, G.J.7
  • 12
    • 58849158388 scopus 로고    scopus 로고
    • How does SIRT1 affect metabolism, senescence and cancer?
    • Brooks C.L., Gu W. How does SIRT1 affect metabolism, senescence and cancer?. Nat. Rev. Cancer 2009, 9:123-128.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 123-128
    • Brooks, C.L.1    Gu, W.2
  • 13
  • 16
    • 79952694643 scopus 로고    scopus 로고
    • Myc: maestro of microRNAs
    • Bui T.V., Mendell J.T. Myc: maestro of microRNAs. Genes Cancer 2010, 1:568-575.
    • (2010) Genes Cancer , vol.1 , pp. 568-575
    • Bui, T.V.1    Mendell, J.T.2
  • 17
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U., Schubert J., Wellner U., Schmalhofer O., Vincan E., Spaderna S., Brabletz T. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep. 2008, 9:582-589.
    • (2008) EMBO Rep. , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6    Brabletz, T.7
  • 18
    • 79955599925 scopus 로고    scopus 로고
    • CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation
    • Burns D.M., D'Ambrogio A., Nottrott S., Richter J.D. CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation. Nature 2011, 473:105-108.
    • (2011) Nature , vol.473 , pp. 105-108
    • Burns, D.M.1    D'Ambrogio, A.2    Nottrott, S.3    Richter, J.D.4
  • 33
    • 84862222969 scopus 로고    scopus 로고
    • The microRNA-17-92 family of microRNA clusters in development and disease
    • Concepcion C.P., Bonetti C., Ventura A. The microRNA-17-92 family of microRNA clusters in development and disease. Cancer J. 2012, 18:262-267.
    • (2012) Cancer J. , vol.18 , pp. 262-267
    • Concepcion, C.P.1    Bonetti, C.2    Ventura, A.3
  • 36
    • 34548803950 scopus 로고    scopus 로고
    • MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
    • Corney D.C., Flesken-Nikitin A., Godwin A.K., Wang W., Nikitin A.Y. MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res. 2007, 67:8433-8438.
    • (2007) Cancer Res. , vol.67 , pp. 8433-8438
    • Corney, D.C.1    Flesken-Nikitin, A.2    Godwin, A.K.3    Wang, W.4    Nikitin, A.Y.5
  • 40
    • 70349320158 scopus 로고    scopus 로고
    • Causes and consequences of microRNA dysregulation in cancer
    • Croce C.M. Causes and consequences of microRNA dysregulation in cancer. Nat. Rev. Genet. 2009, 10:704-714.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 704-714
    • Croce, C.M.1
  • 41
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • Davis B.N., Hilyard A.C., Lagna G., Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008, 454:56-61.
    • (2008) Nature , vol.454 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 43
    • 33745700209 scopus 로고    scopus 로고
    • Sequence variations of microRNAs in human cancer: alterations in predicted secondary structure do not affect processing
    • Diederichs S., Haber D.A. Sequence variations of microRNAs in human cancer: alterations in predicted secondary structure do not affect processing. Cancer Res. 2006, 66:6097-6104.
    • (2006) Cancer Res. , vol.66 , pp. 6097-6104
    • Diederichs, S.1    Haber, D.A.2
  • 47
    • 84861866572 scopus 로고    scopus 로고
    • The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC
    • Fabian M.R., Sonenberg N. The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC. Nat. Struct. Mol. Biol. 2012, 19:586-593.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 586-593
    • Fabian, M.R.1    Sonenberg, N.2
  • 50
    • 40549104113 scopus 로고    scopus 로고
    • Elevated serum-circulating RNA in patients with conventional renal cell cancer
    • Feng G., Li G., Gentil-Perret A., Tostain J., Genin C. Elevated serum-circulating RNA in patients with conventional renal cell cancer. Anticancer Res. 2008, 28:321-326.
    • (2008) Anticancer Res. , vol.28 , pp. 321-326
    • Feng, G.1    Li, G.2    Gentil-Perret, A.3    Tostain, J.4    Genin, C.5
  • 53
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • Frankel L.B., Christoffersen N.R., Jacobsen A., Lindow M., Krogh A., Lund A.H. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J. Biol. Chem. 2008, 283:1026-1033.
    • (2008) J. Biol. Chem. , vol.283 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 54
    • 84868627011 scopus 로고    scopus 로고
    • MicroRNA regulation of Autophagy. Carcinogenesis
    • Frankel, L.B., Lund, A.H. MicroRNA regulation of Autophagy. Carcinogenesis, http://dx.doi.org/10.1093/carcin/bgs266.
    • Frankel, L.B.1    Lund, A.H.2
  • 55
    • 34548168073 scopus 로고    scopus 로고
    • MiR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1
    • Galardi S., Mercatelli N., Giorda E., Massalini S., Frajese G.V., Ciafre S.A., Farace M.G. miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1. J. Biol. Chem. 2007, 282:23716-23724.
    • (2007) J. Biol. Chem. , vol.282 , pp. 23716-23724
    • Galardi, S.1    Mercatelli, N.2    Giorda, E.3    Massalini, S.4    Frajese, G.V.5    Ciafre, S.A.6    Farace, M.G.7
  • 57
    • 77957561284 scopus 로고    scopus 로고
    • Reassessing the TARBP2 mutation rate in hereditary nonpolyposis colorectal cancer
    • author reply 818
    • Garre P., Perez-Segura P., Diaz-Rubio E., Caldes T., de la Hoya M. Reassessing the TARBP2 mutation rate in hereditary nonpolyposis colorectal cancer. Nat. Genet. 2010, 42:817-818. author reply 818.
    • (2010) Nat. Genet. , vol.42 , pp. 817-818
    • Garre, P.1    Perez-Segura, P.2    Diaz-Rubio, E.3    Caldes, T.4    de la Hoya, M.5
  • 58
    • 64049107465 scopus 로고    scopus 로고
    • MiR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis
    • Gebeshuber C.A., Zatloukal K., Martinez J. miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis. EMBO Rep. 2009, 10:400-405.
    • (2009) EMBO Rep. , vol.10 , pp. 400-405
    • Gebeshuber, C.A.1    Zatloukal, K.2    Martinez, J.3
  • 59
    • 33748028804 scopus 로고    scopus 로고
    • Cell cycle control and beyond: emerging roles for the retinoblastoma gene family
    • Genovese C., Trani D., Caputi M., Claudio P.P. Cell cycle control and beyond: emerging roles for the retinoblastoma gene family. Oncogene 2006, 25:5201-5209.
    • (2006) Oncogene , vol.25 , pp. 5201-5209
    • Genovese, C.1    Trani, D.2    Caputi, M.3    Claudio, P.P.4
  • 61
    • 34548268220 scopus 로고    scopus 로고
    • Regulation of p27Kip1 by miRNA 221/222 in glioblastoma
    • Gillies J.K., Lorimer I.A. Regulation of p27Kip1 by miRNA 221/222 in glioblastoma. Cell Cycle 2007, 6:2005-2009.
    • (2007) Cell Cycle , vol.6 , pp. 2005-2009
    • Gillies, J.K.1    Lorimer, I.A.2
  • 63
    • 78149408296 scopus 로고    scopus 로고
    • A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer
    • Hanke M., Hoefig K., Merz H., Feller A.C., Kausch I., Jocham D., Warnecke J.M., Sczakiel G. A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer. Urol. Oncol. 2010, 28:655-661.
    • (2010) Urol. Oncol. , vol.28 , pp. 655-661
    • Hanke, M.1    Hoefig, K.2    Merz, H.3    Feller, A.C.4    Kausch, I.5    Jocham, D.6    Warnecke, J.M.7    Sczakiel, G.8
  • 66
    • 35548957247 scopus 로고    scopus 로고
    • MicroRNAs join the p53 network - another piece in the tumour-suppression puzzle
    • He L., He X., Lowe S.W., Hannon G.J. microRNAs join the p53 network - another piece in the tumour-suppression puzzle. Nat. Rev. Cancer 2007, 7:819-822.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 819-822
    • He, L.1    He, X.2    Lowe, S.W.3    Hannon, G.J.4
  • 68
    • 84859309077 scopus 로고    scopus 로고
    • MicroRNAs and stem cells: control of pluripotency, reprogramming, and lineage commitment
    • Heinrich E.M., Dimmeler S. MicroRNAs and stem cells: control of pluripotency, reprogramming, and lineage commitment. Circ. Res. 2012, 110:1014-1022.
    • (2012) Circ. Res. , vol.110 , pp. 1014-1022
    • Heinrich, E.M.1    Dimmeler, S.2
  • 69
    • 84858055716 scopus 로고    scopus 로고
    • The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle
    • Henley S.A., Dick F.A. The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle. Cell Div. 2012, 7:10.
    • (2012) Cell Div. , vol.7 , pp. 10
    • Henley, S.A.1    Dick, F.A.2
  • 70
    • 74249123570 scopus 로고    scopus 로고
    • The miR-34 family in cancer and apoptosis
    • Hermeking H. The miR-34 family in cancer and apoptosis. Cell. Death. Differ. 2010, 17:193-199.
    • (2010) Cell. Death. Differ. , vol.17 , pp. 193-199
    • Hermeking, H.1
  • 71
    • 84866423871 scopus 로고    scopus 로고
    • MicroRNAs in the p53 network: micromanagement of tumour suppression
    • Hermeking H. MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat. Rev. Cancer 2012, 12:613-626.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 613-626
    • Hermeking, H.1
  • 72
    • 77954517267 scopus 로고    scopus 로고
    • MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems
    • Herranz H., Cohen S.M. MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems. Genes Dev. 2010, 24:1339-1344.
    • (2010) Genes Dev. , vol.24 , pp. 1339-1344
    • Herranz, H.1    Cohen, S.M.2
  • 73
    • 84984765621 scopus 로고    scopus 로고
    • Canalization of development by microRNAs
    • Hornstein E., Shomron N. Canalization of development by microRNAs. Nat. Genet. 2006, 38(Suppl. 1):S20-S24.
    • (2006) Nat. Genet. , vol.38 , Issue.SUPPL 1
    • Hornstein, E.1    Shomron, N.2
  • 78
    • 77956547097 scopus 로고    scopus 로고
    • Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells
    • Iliopoulos D., Lindahl-Allen M., Polytarchou C., Hirsch H.A., Tsichlis P.N., Struhl K. Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Mol. Cell. 2010, 39:761-772.
    • (2010) Mol. Cell. , vol.39 , pp. 761-772
    • Iliopoulos, D.1    Lindahl-Allen, M.2    Polytarchou, C.3    Hirsch, H.A.4    Tsichlis, P.N.5    Struhl, K.6
  • 79
    • 84858126071 scopus 로고    scopus 로고
    • MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
    • Iorio M.V., Croce C.M. MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol. Med. 2012, 4:143-159.
    • (2012) EMBO Mol. Med. , vol.4 , pp. 143-159
    • Iorio, M.V.1    Croce, C.M.2
  • 86
    • 81855224576 scopus 로고    scopus 로고
    • Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy
    • Kasinski A.L., Slack F.J. Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat. Rev. Cancer 2011, 11:849-864.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 849-864
    • Kasinski, A.L.1    Slack, F.J.2
  • 87
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • Kastan M.B., Bartek J. Cell-cycle checkpoints and cancer. Nature 2004, 432:316-323.
    • (2004) Nature , vol.432 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 89
    • 77957564277 scopus 로고    scopus 로고
    • A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibility
    • Kedde M., van Kouwenhove M., Zwart W., Oude Vrielink J.A., Elkon R., Agami R. A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibility. Nat. Cell. Biol. 2010, 12:1014-1020.
    • (2010) Nat. Cell. Biol. , vol.12 , pp. 1014-1020
    • Kedde, M.1    van Kouwenhove, M.2    Zwart, W.3    Oude Vrielink, J.A.4    Elkon, R.5    Agami, R.6
  • 94
    • 78649429749 scopus 로고    scopus 로고
    • MicroRNAs and their therapeutic potential for human diseases: microRNAs, miR-143 and -145, function as anti-oncomirs and the application of chemically modified miR-143 as an anti-cancer drug
    • Kitade Y., Akao Y. MicroRNAs and their therapeutic potential for human diseases: microRNAs, miR-143 and -145, function as anti-oncomirs and the application of chemically modified miR-143 as an anti-cancer drug. J. Pharmacol. Sci. 2010, 114:276-280.
    • (2010) J. Pharmacol. Sci. , vol.114 , pp. 276-280
    • Kitade, Y.1    Akao, Y.2
  • 102
    • 34247593034 scopus 로고    scopus 로고
    • Impaired microRNA processing enhances cellular transformation and tumorigenesis
    • Kumar M.S., Lu J., Mercer K.L., Golub T.R., Jacks T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat. Genet. 2007, 39:673-677.
    • (2007) Nat. Genet. , vol.39 , pp. 673-677
    • Kumar, M.S.1    Lu, J.2    Mercer, K.L.3    Golub, T.R.4    Jacks, T.5
  • 104
    • 77956214409 scopus 로고    scopus 로고
    • Variability in the incidence of miRNAs and genes in fragile sites and the role of repeats and CpG islands in the distribution of genetic material
    • Lagana A., Russo F., Sismeiro C., Giugno R., Pulvirenti A., Ferro A. Variability in the incidence of miRNAs and genes in fragile sites and the role of repeats and CpG islands in the distribution of genetic material. PLoS One 2010, 5:e11166.
    • (2010) PLoS One , vol.5
    • Lagana, A.1    Russo, F.2    Sismeiro, C.3    Giugno, R.4    Pulvirenti, A.5    Ferro, A.6
  • 105
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana M., Rauhut R., Lendeckel W., Tuschl T. Identification of novel genes coding for small expressed RNAs. Science 2001, 294:853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 111
    • 34249946434 scopus 로고    scopus 로고
    • The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells
    • Laneve P., Di Marcotullio L., Gioia U., Fiori M.E., Ferretti E., Gulino A., Bozzoni I., Caffarelli E. The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells. Proc. Natl. Acad. Sci. USA 2007, 104:7957-7962.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 7957-7962
    • Laneve, P.1    Di Marcotullio, L.2    Gioia, U.3    Fiori, M.E.4    Ferretti, E.5    Gulino, A.6    Bozzoni, I.7    Caffarelli, E.8
  • 114
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau N.C., Lim L.P., Weinstein E.G., Bartel D.P. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 2001, 294:858-862.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 118
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee R.C., Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science 2001, 294:862-864.
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 119
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 121
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee Y.S., Dutta A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev. 2007, 21:1025-1030.
    • (2007) Genes Dev. , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 123
    • 84870823182 scopus 로고    scopus 로고
    • Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo. Oncogene
    • Leucci, E., Zriwil, A., Gregersen, L.H., Jensen, K.T., Obad, S., Bellan, C., Leoncini, L., Kauppinen, S., Lund, A.H. Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo. Oncogene, http://dx.doi.org/10.1038/onc.2012.15.
    • Leucci, E.1    Zriwil, A.2    Gregersen, L.H.3    Jensen, K.T.4    Obad, S.5    Bellan, C.6    Leoncini, L.7    Kauppinen, S.8    Lund, A.H.9
  • 124
    • 36949029208 scopus 로고    scopus 로고
    • Small regulatory RNAs may sharpen spatial expression patterns
    • Levine E., McHale P., Levine H. Small regulatory RNAs may sharpen spatial expression patterns. PLoS Comput. Biol. 2007, 3:e233.
    • (2007) PLoS Comput. Biol. , vol.3
    • Levine, E.1    McHale, P.2    Levine, H.3
  • 125
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis B.P., Burge C.B., Bartel D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005, 120:15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 126
    • 76749157966 scopus 로고    scopus 로고
    • MiR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway
    • Li J., Donath S., Li Y., Qin D., Prabhakar B.S., Li P. miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway. PLoS Genet. 2010, 6:e1000795.
    • (2010) PLoS Genet. , vol.6
    • Li, J.1    Donath, S.2    Li, Y.3    Qin, D.4    Prabhakar, B.S.5    Li, P.6
  • 131
    • 84865093689 scopus 로고    scopus 로고
    • MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN
    • Liu B., Wu X., Liu B., Wang C., Liu Y., Zhou Q., Xu K. MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN. Biochim. Biophys. Acta 2012, 1822:1692-1704.
    • (2012) Biochim. Biophys. Acta , vol.1822 , pp. 1692-1704
    • Liu, B.1    Wu, X.2    Liu, B.3    Wang, C.4    Liu, Y.5    Zhou, Q.6    Xu, K.7
  • 134
    • 76749102887 scopus 로고    scopus 로고
    • E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis
    • Lize M., Pilarski S., Dobbelstein M. E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis. Cell. Death Differ. 2010, 17:452-458.
    • (2010) Cell. Death Differ. , vol.17 , pp. 452-458
    • Lize, M.1    Pilarski, S.2    Dobbelstein, M.3
  • 135
    • 84860408968 scopus 로고    scopus 로고
    • DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer
    • Lopez-Serra P., Esteller M. DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer. Oncogene 2012, 31:1609-1622.
    • (2012) Oncogene , vol.31 , pp. 1609-1622
    • Lopez-Serra, P.1    Esteller, M.2
  • 139
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma L., Teruya-Feldstein J., Weinberg R.A. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007, 449:682-688.
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 140
    • 77955871461 scopus 로고    scopus 로고
    • The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor
    • Manfredi J.J. The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor. Genes Dev. 2010, 24:1580-1589.
    • (2010) Genes Dev. , vol.24 , pp. 1580-1589
    • Manfredi, J.J.1
  • 144
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • Mayr C., Bartel D.P. Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 2009, 138:673-684.
    • (2009) Cell , vol.138 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2
  • 145
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • Mayr C., Hemann M.T., Bartel D.P. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 2007, 315:1576-1579.
    • (2007) Science , vol.315 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 146
    • 77956339881 scopus 로고    scopus 로고
    • OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
    • Medina P.P., Nolde M., Slack F.J. OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature 2010, 467:86-90.
    • (2010) Nature , vol.467 , pp. 86-90
    • Medina, P.P.1    Nolde, M.2    Slack, F.J.3
  • 149
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F., Henson R., Wehbe-Janek H., Ghoshal K., Jacob S.T., Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007, 133:647-658.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 150
    • 42449110323 scopus 로고    scopus 로고
    • MiRSNPs or MiR-polymorphisms, new players in microRNA mediated regulation of the cell: introducing microRNA pharmacogenomics
    • Mishra P.J., Mishra P.J., Banerjee D., Bertino J.R. MiRSNPs or MiR-polymorphisms, new players in microRNA mediated regulation of the cell: introducing microRNA pharmacogenomics. Cell Cycle 2008, 7:853-858.
    • (2008) Cell Cycle , vol.7 , pp. 853-858
    • Mishra, P.J.1    Mishra, P.J.2    Banerjee, D.3    Bertino, J.R.4
  • 152
    • 34548687035 scopus 로고    scopus 로고
    • Mir-29 regulates Mcl-1 protein expression and apoptosis
    • Mott J.L., Kobayashi S., Bronk S.F., Gores G.J. mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 2007, 26:6133-6140.
    • (2007) Oncogene , vol.26 , pp. 6133-6140
    • Mott, J.L.1    Kobayashi, S.2    Bronk, S.F.3    Gores, G.J.4
  • 154
    • 78951475020 scopus 로고    scopus 로고
    • P53 and its mutants in tumor cell migration and invasion
    • Muller P.A., Vousden K.H., Norman J.C. p53 and its mutants in tumor cell migration and invasion. J. Cell. Biol. 2011, 192:209-218.
    • (2011) J. Cell. Biol. , vol.192 , pp. 209-218
    • Muller, P.A.1    Vousden, K.H.2    Norman, J.C.3
  • 155
    • 79956190689 scopus 로고    scopus 로고
    • MicroRNA profiling in cancer
    • Munker R., Calin G.A. MicroRNA profiling in cancer. Clin. Sci. (Lond.) 2011, 121:141-158.
    • (2011) Clin. Sci. (Lond.) , vol.121 , pp. 141-158
    • Munker, R.1    Calin, G.A.2
  • 157
    • 0842324788 scopus 로고    scopus 로고
    • Recycling the cell cycle: cyclins revisited
    • Murray A.W. Recycling the cell cycle: cyclins revisited. Cell 2004, 116:221-234.
    • (2004) Cell , vol.116 , pp. 221-234
    • Murray, A.W.1
  • 159
    • 77953032534 scopus 로고    scopus 로고
    • Emerging paradigms of regulated microRNA processing
    • Newman M.A., Hammond S.M. Emerging paradigms of regulated microRNA processing. Genes Dev. 2010, 24:1086-1092.
    • (2010) Genes Dev. , vol.24 , pp. 1086-1092
    • Newman, M.A.1    Hammond, S.M.2
  • 160
    • 66049112674 scopus 로고    scopus 로고
    • Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening
    • Ng E.K., Chong W.W., Jin H., Lam E.K., Shin V.Y., Yu J., Poon T.C., Ng S.S., Sung J.J. Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut 2009, 58:1375-1381.
    • (2009) Gut , vol.58 , pp. 1375-1381
    • Ng, E.K.1    Chong, W.W.2    Jin, H.3    Lam, E.K.4    Shin, V.Y.5    Yu, J.6    Poon, T.C.7    Ng, S.S.8    Sung, J.J.9
  • 161
    • 53749098061 scopus 로고    scopus 로고
    • Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression
    • Nishino J., Kim I., Chada K., Morrison S.J. Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. Cell 2008, 135:227-239.
    • (2008) Cell , vol.135 , pp. 227-239
    • Nishino, J.1    Kim, I.2    Chada, K.3    Morrison, S.J.4
  • 170
    • 70349577785 scopus 로고    scopus 로고
    • Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling
    • Paroo Z., Ye X., Chen S., Liu Q. Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling. Cell 2009, 139:112-122.
    • (2009) Cell , vol.139 , pp. 112-122
    • Paroo, Z.1    Ye, X.2    Chen, S.3    Liu, Q.4
  • 171
    • 65349162096 scopus 로고    scopus 로고
    • Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression
    • Peter M.E. Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression. Cell Cycle 2009, 8:843-852.
    • (2009) Cell Cycle , vol.8 , pp. 843-852
    • Peter, M.E.1
  • 173
    • 58149328931 scopus 로고    scopus 로고
    • MiR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression
    • Pickering M.T., Stadler B.M., Kowalik T.F. miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression. Oncogene 2008, 28:140-145.
    • (2008) Oncogene , vol.28 , pp. 140-145
    • Pickering, M.T.1    Stadler, B.M.2    Kowalik, T.F.3
  • 174
    • 70349437076 scopus 로고    scopus 로고
    • P53 and E2f: partners in life and death
    • Polager S., Ginsberg D. p53 and E2f: partners in life and death. Nat. Rev. Cancer 2009, 9:738-748.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 738-748
    • Polager, S.1    Ginsberg, D.2
  • 175
    • 77953957633 scopus 로고    scopus 로고
    • A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
    • Poliseno L., Salmena L., Zhang J., Carver B., Haveman W.J., Pandolfi P.P. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 2010, 465:1033-1038.
    • (2010) Nature , vol.465 , pp. 1033-1038
    • Poliseno, L.1    Salmena, L.2    Zhang, J.3    Carver, B.4    Haveman, W.J.5    Pandolfi, P.P.6
  • 176
    • 80053604703 scopus 로고    scopus 로고
    • Spatiotemporal aspects of MicroRNA-mediated gene regulation
    • Pothof J., van Gent D.C. Spatiotemporal aspects of MicroRNA-mediated gene regulation. Adv. Exp. Med. Biol. 2011, 722:75-85.
    • (2011) Adv. Exp. Med. Biol. , vol.722 , pp. 75-85
    • Pothof, J.1    van Gent, D.C.2
  • 178
    • 80051590849 scopus 로고    scopus 로고
    • Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice
    • Pramanik D., Campbell N.R., Karikari C., Chivukula R., Kent O.A., Mendell J.T., Maitra A. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol. Cancer Ther. 2011, 10:1470-1480.
    • (2011) Mol. Cancer Ther. , vol.10 , pp. 1470-1480
    • Pramanik, D.1    Campbell, N.R.2    Karikari, C.3    Chivukula, R.4    Kent, O.A.5    Mendell, J.T.6    Maitra, A.7
  • 181
    • 57649091633 scopus 로고    scopus 로고
    • The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform
    • Resnick K.E., Alder H., Hagan J.P., Richardson D.L., Croce C.M., Cohn D.E. The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform. Gynecol. Oncol. 2009, 112:55-59.
    • (2009) Gynecol. Oncol. , vol.112 , pp. 55-59
    • Resnick, K.E.1    Alder, H.2    Hagan, J.P.3    Richardson, D.L.4    Croce, C.M.5    Cohn, D.E.6
  • 184
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
    • Saito Y., Liang G., Egger G., Friedman J.M., Chuang J.C., Coetzee G.A., Jones P.A. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 2006, 9:435-443.
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3    Friedman, J.M.4    Chuang, J.C.5    Coetzee, G.A.6    Jones, P.A.7
  • 185
    • 79960912980 scopus 로고    scopus 로고
    • Control of microRNA biogenesis and transcription by cell signaling pathways
    • Saj A., Lai E.C. Control of microRNA biogenesis and transcription by cell signaling pathways. Curr. Opin. Genet. Develop. 2011, 21:504-510.
    • (2011) Curr. Opin. Genet. Develop. , vol.21 , pp. 504-510
    • Saj, A.1    Lai, E.C.2
  • 186
    • 79961170994 scopus 로고    scopus 로고
    • A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?
    • Salmena L., Poliseno L., Tay Y., Kats L., Pandolfi P.P. A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?. Cell 2011, 146:353-358.
    • (2011) Cell , vol.146 , pp. 353-358
    • Salmena, L.1    Poliseno, L.2    Tay, Y.3    Kats, L.4    Pandolfi, P.P.5
  • 188
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites
    • Sandberg R., Neilson J.R., Sarma A., Sharp P.A., Burge C.B. Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites. Science 2008, 320:1643-1647.
    • (2008) Science , vol.320 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 189
    • 77954210384 scopus 로고    scopus 로고
    • MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by down-regulation of Cdc25A
    • Sarkar S., Dey B.K., Dutta A. MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by down-regulation of Cdc25A. Mol. Biol. Cell. 2010, 21:2138-2149.
    • (2010) Mol. Biol. Cell. , vol.21 , pp. 2138-2149
    • Sarkar, S.1    Dey, B.K.2    Dutta, A.3
  • 190
    • 32944462300 scopus 로고    scopus 로고
    • Rapid alteration of microRNA levels by histone deacetylase inhibition
    • Scott G.K., Mattie M.D., Berger C.E., Benz S.C., Benz C.C. Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res. 2006, 66:1277-1281.
    • (2006) Cancer Res. , vol.66 , pp. 1277-1281
    • Scott, G.K.1    Mattie, M.D.2    Berger, C.E.3    Benz, S.C.4    Benz, C.C.5
  • 191
    • 67349123973 scopus 로고    scopus 로고
    • Redefining microRNA targets
    • Seitz H. Redefining microRNA targets. Curr. Biol. 2009, 19:870-873.
    • (2009) Curr. Biol. , vol.19 , pp. 870-873
    • Seitz, H.1
  • 192
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr C.J. Cancer cell cycles. Science 1996, 274:1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 194
    • 67651002343 scopus 로고    scopus 로고
    • Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell
    • Sotiropoulou G., Pampalakis G., Lianidou E., Mourelatos Z. Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell. RNA 2009, 15:1443-1461.
    • (2009) RNA , vol.15 , pp. 1443-1461
    • Sotiropoulou, G.1    Pampalakis, G.2    Lianidou, E.3    Mourelatos, Z.4
  • 195
    • 29244434544 scopus 로고    scopus 로고
    • MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
    • Stucki M., Clapperton J.A., Mohammad D., Yaffe M.B., Smerdon S.J., Jackson S.P. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 2005, 123:1213-1226.
    • (2005) Cell , vol.123 , pp. 1213-1226
    • Stucki, M.1    Clapperton, J.A.2    Mohammad, D.3    Yaffe, M.B.4    Smerdon, S.J.5    Jackson, S.P.6
  • 199
  • 200
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest
    • Tarasov V., Jung P., Verdoodt B., Lodygin D., Epanchintsev A., Menssen A., Meister G., Hermeking H. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 2007, 6:1586-1593.
    • (2007) Cell Cycle , vol.6 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3    Lodygin, D.4    Epanchintsev, A.5    Menssen, A.6    Meister, G.7    Hermeking, H.8
  • 201
    • 34848868157 scopus 로고    scopus 로고
    • Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
    • Tazawa H., Tsuchiya N., Izumiya M., Nakagama H. Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc. Natl. Acad. Sci. USA 2007, 104:15472-15477.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 15472-15477
    • Tazawa, H.1    Tsuchiya, N.2    Izumiya, M.3    Nakagama, H.4
  • 204
    • 49249121155 scopus 로고    scopus 로고
    • Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
    • Toyota M., Suzuki H., Sasaki Y., Maruyama R., Imai K., Shinomura Y., Tokino T. Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res. 2008, 68:4123-4132.
    • (2008) Cancer Res. , vol.68 , pp. 4123-4132
    • Toyota, M.1    Suzuki, H.2    Sasaki, Y.3    Maruyama, R.4    Imai, K.5    Shinomura, Y.6    Tokino, T.7
  • 208
    • 77950348609 scopus 로고    scopus 로고
    • Genome-wide dissection of microRNA functions and cotargeting networks using gene set signatures
    • Tsang J.S., Ebert M.S., van Oudenaarden A. Genome-wide dissection of microRNA functions and cotargeting networks using gene set signatures. Mol. Cell. 2010, 38:140-153.
    • (2010) Mol. Cell. , vol.38 , pp. 140-153
    • Tsang, J.S.1    Ebert, M.S.2    van Oudenaarden, A.3
  • 211
    • 77049099101 scopus 로고    scopus 로고
    • Lin28: a microRNA regulator with a macro role
    • Viswanathan S.R., Daley G.Q. Lin28: a microRNA regulator with a macro role. Cell 2010, 140:445-449.
    • (2010) Cell , vol.140 , pp. 445-449
    • Viswanathan, S.R.1    Daley, G.Q.2
  • 214
    • 77952543499 scopus 로고    scopus 로고
    • The p53 orchestra: Mdm2 and Mdmx set the tone
    • Wade M., Wang Y.V., Wahl G.M. The p53 orchestra: Mdm2 and Mdmx set the tone. Trends Cell. Biol. 2010, 20:299-309.
    • (2010) Trends Cell. Biol. , vol.20 , pp. 299-309
    • Wade, M.1    Wang, Y.V.2    Wahl, G.M.3
  • 215
    • 77956542998 scopus 로고    scopus 로고
    • CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer
    • Wang J., Liu X., Wu H., Ni P., Gu Z., Qiao Y., Chen N., Sun F., Fan Q. CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer. Nucleic Acids Res. 2010, 38:5366-5383.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 5366-5383
    • Wang, J.1    Liu, X.2    Wu, H.3    Ni, P.4    Gu, Z.5    Qiao, Y.6    Chen, N.7    Sun, F.8    Fan, Q.9
  • 217
    • 34248217444 scopus 로고    scopus 로고
    • Methylation of human microRNA genes in normal and neoplastic cells
    • Weber B., Stresemann C., Brueckner B., Lyko F. Methylation of human microRNA genes in normal and neoplastic cells. Cell Cycle 2007, 6:1001-1005.
    • (2007) Cell Cycle , vol.6 , pp. 1001-1005
    • Weber, B.1    Stresemann, C.2    Brueckner, B.3    Lyko, F.4
  • 218
    • 84866550833 scopus 로고    scopus 로고
    • Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer
    • Wee E.J., Peters K., Nair S.S., Hulf T., Stein S., Wagner S., Bailey P., Lee S.Y., Qu W.J., Brewster B., French J.D., Dobrovic A., Francis G.D., Clark S.J., Brown M.A. Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer. Oncogene 2012, 31:4182-4195.
    • (2012) Oncogene , vol.31 , pp. 4182-4195
    • Wee, E.J.1    Peters, K.2    Nair, S.S.3    Hulf, T.4    Stein, S.5    Wagner, S.6    Bailey, P.7    Lee, S.Y.8    Qu, W.J.9    Brewster, B.10    French, J.D.11    Dobrovic, A.12    Francis, G.D.13    Clark, S.J.14    Brown, M.A.15
  • 219
    • 34249812122 scopus 로고    scopus 로고
    • MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
    • Welch C., Chen Y., Stallings R.L. MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene 2007, 26:5017-5022.
    • (2007) Oncogene , vol.26 , pp. 5017-5022
    • Welch, C.1    Chen, Y.2    Stallings, R.L.3
  • 220
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • Wightman B., Ha I., Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 1993, 75:855-862.
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 221
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods K., Thomson J.M., Hammond S.M. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J. Biol. Chem. 2007, 282:2130-2134.
    • (2007) J. Biol. Chem. , vol.282 , pp. 2130-2134
    • Woods, K.1    Thomson, J.M.2    Hammond, S.M.3
  • 222
    • 77951092028 scopus 로고    scopus 로고
    • Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region
    • Wu S., Huang S., Ding J., Zhao Y., Liang L., Liu T., Zhan R., He X. Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region. Oncogene 2010, 29:2302-2308.
    • (2010) Oncogene , vol.29 , pp. 2302-2308
    • Wu, S.1    Huang, S.2    Ding, J.3    Zhao, Y.4    Liang, L.5    Liu, T.6    Zhan, R.7    He, X.8
  • 226
    • 79551610902 scopus 로고    scopus 로고
    • MiR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress
    • Xiao J., Lin H., Luo X., Wang Z. miR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress. EMBO J. 2011, 30:524-532.
    • (2011) EMBO J. , vol.30 , pp. 524-532
    • Xiao, J.1    Lin, H.2    Luo, X.3    Wang, Z.4
  • 229
    • 62449117918 scopus 로고    scopus 로고
    • MiR-34, SIRT1 and p53: the feedback loop
    • Yamakuchi M., Lowenstein C.J. MiR-34, SIRT1 and p53: the feedback loop. Cell Cycle 2009, 8:712-715.
    • (2009) Cell Cycle , vol.8 , pp. 712-715
    • Yamakuchi, M.1    Lowenstein, C.J.2
  • 230
    • 70349220767 scopus 로고    scopus 로고
    • Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis
    • Yan H.L., Xue G., Mei Q., Wang Y.Z., Ding F.X., Liu M.F., Lu M.H., Tang Y., Yu H.Y., Sun S.H. Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis. EMBO J. 2009, 28:2719-2732.
    • (2009) EMBO J. , vol.28 , pp. 2719-2732
    • Yan, H.L.1    Xue, G.2    Mei, Q.3    Wang, Y.Z.4    Ding, F.X.5    Liu, M.F.6    Lu, M.H.7    Tang, Y.8    Yu, H.Y.9    Sun, S.H.10
  • 231
    • 70350111289 scopus 로고    scopus 로고
    • MiR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A
    • Yang X., Feng M., Jiang X., Wu Z., Li Z., Aau M., Yu Q. miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A. Genes Dev. 2009, 23:2388-2393.
    • (2009) Genes Dev. , vol.23 , pp. 2388-2393
    • Yang, X.1    Feng, M.2    Jiang, X.3    Wu, Z.4    Li, Z.5    Aau, M.6    Yu, Q.7
  • 232
    • 40749111551 scopus 로고    scopus 로고
    • A skin microRNA promotes differentiation by repressing 'stemness'
    • Yi R., Poy M.N., Stoffel M., Fuchs E. A skin microRNA promotes differentiation by repressing 'stemness'. Nature 2008, 452:225-229.
    • (2008) Nature , vol.452 , pp. 225-229
    • Yi, R.1    Poy, M.N.2    Stoffel, M.3    Fuchs, E.4
  • 233
    • 34547843634 scopus 로고    scopus 로고
    • Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers
    • Yu Z., Li Z., Jolicoeur N., Zhang L., Fortin Y., Wang E., Wu M., Shen S.H. Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers. Nucleic Acids Res. 2007, 35:4535-4541.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 4535-4541
    • Yu, Z.1    Li, Z.2    Jolicoeur, N.3    Zhang, L.4    Fortin, Y.5    Wang, E.6    Wu, M.7    Shen, S.H.8
  • 235
    • 84871958603 scopus 로고    scopus 로고
    • Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. Oncogene
    • Zhang, J., Sun, Q., Zhang, Z., Ge, S., Han, Z.G., Chen, W.T. Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. Oncogene, http://dx.doi.org/10.1038/onc.2012.28.
    • Zhang, J.1    Sun, Q.2    Zhang, Z.3    Ge, S.4    Han, Z.G.5    Chen, W.T.6
  • 236
    • 79951500251 scopus 로고    scopus 로고
    • The ATM kinase induces microRNA biogenesis in the DNA damage response
    • Zhang X., Wan G., Berger F.G., He X., Lu X. The ATM kinase induces microRNA biogenesis in the DNA damage response. Mol. Cell. 2011, 41:371-383.
    • (2011) Mol. Cell. , vol.41 , pp. 371-383
    • Zhang, X.1    Wan, G.2    Berger, F.G.3    He, X.4    Lu, X.5


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