MiR-137 suppresses cell growth in ovarian cancer by targeting AEG-1

Biochemical and Biophysical Research Communications

Volumn 441, Issue 2, 2013, Pages 357-363

  Guo, Jinling ^a   Xia, Bairong ^a   Meng, Fanling ^a   Lou, Ge ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

AEG 1; Cell growth; miR 137; Ovarian cancer

Indexed keywords

COMPLEMENTARY DNA; MICRORNA; MICRORNA 137; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE ELEVATED GENE 1; CANCER CELL; CANCER INHIBITION; CELL CYCLE; CELL GROWTH; CELL STRAIN HEK293; CELL VIABILITY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC TRANSDUCTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LENTIVIRINAE; MOUSE; NONHUMAN; NUDE MOUSE; ONCOGENE; OVARY CANCER; PLASMID; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS RECOMBINANT; WESTERN BLOTTING;

AEG-1; CELL GROWTH; MIR-137; OVARIAN CANCER;

3' UNTRANSLATED REGIONS; ANIMALS; CARCINOGENESIS; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; FEMALE; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; MICE; MICE, NUDE; MICRORNAS; OVARIAN NEOPLASMS;

MUS MUSCULUS;

EID: 84888013022     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.10.052     Document Type: Article

References (35)

1. D.M. Parkin, F. Bray, and P. Pisani Estimating the world cancer burden: Globocan 2000 Int. J. Cancer 94 2001 153 156
2. T.M. Zaid, T.L. Yeung, M.S. Thompson, C.S. Leung, T. Harding, N.N. Co, R.S. Schmandt, S.Y. Kwan, C. Rodriguez-Aguay, G. Lopez-Berestein, A.K. Sood, K.K. Wong, M.J. Birrer, and S.C. Mok Identification of FGFR4 as a potential therapeutic target for advanced-stage, high-grade serous ovarian cancer Clin. Cancer Res. 19 2013 809 820
3. R.T. Greenlee, M.B. Hill-Harmon, T. Murray, and M. Thun Cancer statistics, 2001 CA Cancer J. Clin. 51 2001 15 36
4. T.G. Grunewald, U. Kammerer, C. Winkler, D. Schindler, A. Sickmann, A. Honig, and E. Butt Overexpression of LASP-1 mediates migration and proliferation of human ovarian cancer cells and influences zyxin localization Br. J. Cancer 96 2007 296 305
5. D.M. Brown, and E. Ruoslahti Metadherin, a cell surface protein in breast tumours that mediates lung metastasis Cancer Cell 5 2004 365 374
6. Z.Z. Su, D.C. Kang, Y. Chen, O. Pekarskaya, W. Chao, D.J. Volsky, and P.B. Fisher Identification and cloning of human astrocyte genes displaying elevated expression after infection with HIV-1 or exposure to HIV-1 envelope glycoprotein by rapid subtraction hybridization, RaSH Oncogene 21 2002 3592 3602
7. J. Li, N. Zhang, L.B. Song, W.T. Liao, L.L. Jiang, L.Y. Gong, J. Wu, J. Yuan, H.Z. Zhang, M.S. Zeng, and M. Li Astrocyte elevated gene-1 is a novel prognostic marker for breast cancer progression and overall patient survival Clin. Cancer Res. 14 2008 3319 3326
8. L. Liu, J. Wu, Z. Ying, B. Chen, A. Han, Y. Liang, L. Song, J. Yuan, J. Li, and M. Li Astrocyte elevated gene-1 upregulates matrix metalloproteinase-9 and induces human glioma invasion Cancer Res. 70 2010 3750 3759
9. S.C. Ash, D.Q. Yang, and D.E. Britt LYRIC/AEG-1 overexpression modulates BCCIPalpha protein levels in prostate tumor cells Biochem. Biophys. Res. Commun. 371 2008 333 338
10. C. Yu, K. Chen, H. Zheng, X. Guo, W. Jia, M. Li, M. Zeng, J. Li, and L. Song Overexpression of astrocyte elevated gene-1 (AEG-1) is associated with esophageal squamous cell carcinoma (ESCC) progression and pathogenesis Carcinogenesis 30 2009 894 901
11. L. Emdad, D. Sarkar, Z.Z. Su, S.G. Lee, D.C. Kang, J.N. Bruce, D.J. Volsky, and P.B. Fisher Astrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration Pharmacol. Ther. 114 2007 155 170
12. G. Hu, Y. Wei, and Y. Kang The multifaceted role of MTDH/AEG-1 in cancer progression Clin. Cancer Res. 15 2009 5615 5620
13. X.X. He, Y. Chang, F.Y. Meng, M.Y. Wang, Q.H. Xie, F. Tang, P.Y. Li, Y.H. Song, and J.S. Lin MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo Oncogene 31 2012 3357 3369
14. F. Meng, C. Luo, L. Ma, Y. Hu, and G. Lou Clinical significance of astrocyte elevated gene-1 expression in human epithelial ovarian carcinoma Int. J. Gynecol. Pathol. 30 2011 145 150
15. E. Lund, S. Guttinger, A. Calado, J.E. Dahlberg, and U. Kutay Nuclear export of microRNA precursors Science 303 2004 95 98
16. S. Yang, Y. Li, J. Gao, T. Zhang, S. Li, A. Luo, H. Chen, F. Ding, X. Wang, and Z. Liu MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1 Oncogene 32 36 2013 4294 4303
17. R. Bhattacharya, M. Nicoloso, R. Arvizo, E. Wang, A. Cortez, S. Rossi, G.A. Calin, and P. Mukherjee MiR-15a and MiR-16 control Bmi-1 expression in ovarian cancer Cancer Res. 69 2009 9090 9095
18. C.J. Creighton, M.D. Fountain, Z. Yu, A.K. Nagaraja, H. Zhu, M. Khan, E. Olokpa, A. Zariff, P.H. Gunaratne, M.M. Matzuk, and M.L. Anderson Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers Cancer Res. 70 2010 1906 1915
19. Y. Guan, H. Yao, Z. Zheng, G. Qiu, and K. Sun MiR-125b targets BCL3 and suppresses ovarian cancer proliferation Int. J. Cancer 128 2011 2274 2283
20. A. Chao, C.Y. Lin, Y.S. Lee, C.L. Tsai, P.C. Wei, S. Hsueh, T.I. Wu, C.N. Tsai, C.J. Wang, A.S. Chao, T.H. Wang, and C.H. Lai Regulation of ovarian cancer progression by microRNA-187 through targeting disabled homolog-2 Oncogene 31 2012 764 775
21. Y.Q. Wang, R.D. Guo, R.M. Guo, W. Sheng, and L.R. Yin MicroRNA-182 promotes cell growth, invasion, and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas J. Cell. Biochem. 114 2013 1464 1473
22. Q. Chen, X. Chen, M. Zhang, Q. Fan, S. Luo, and X. Cao miR-137 is frequently down-regulated in gastric cancer and is a negative regulator of Cdc42 Dig. Dis. Sci. 56 2011 2009 2016
23. L. Chen, X. Wang, H. Wang, Y. Li, W. Yan, L. Han, K. Zhang, J. Zhang, Y. Wang, Y. Feng, P. Pu, T. Jiang, C. Kang, and C. Jiang miR-137 is frequently down-regulated in glioblastoma and is a negative regulator of Cox-2 Eur. J. Cancer 48 2012 3104 3111
24. X. Zhu, Y. Li, H. Shen, H. Li, L. Long, L. Hui, and W. Xu miR-137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6 FEBS Lett. 587 2013 73 81
25. L. Liang, X. Li, X. Zhang, Z. Lv, G. He, W. Zhao, X. Ren, Y. Li, X. Bian, W. Liao, W. Liu, G. Yang, and Y. Ding MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2 Gastroenterology 144 2013 624-635.e4
26. K. Althoff, A. Beckers, A. Odersky, P. Mestdagh, J. Köster, I.M. Bray, K. Bryan, J. Vandesompele, F. Speleman, R.L. Stallings, A. Schramm, A. Eggert, A. Sprüssel, and J.H. Schulte MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A Int. J. Cancer 133 2013 1064 1073
27. F. Zheng, Y.J. Liao, M.Y. Cai, Y.H. Liu, T.H. Liu, S.P. Chen, X.W. Bian, X.Y. Guan, M.C. Lin, Y.X. Zeng, H.F. Kung, and D. Xie The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2 Gut 61 2012 278 289
28. C.M. Metallo, P.A. Gameiro, E.L. Bell, K.R. Mattaini, J. Yang, K. Hiller, C.M. Jewell, Z.R. Johnson, D.J. Irvine, L. Guarente, J.K. Kelleher, M.G. Vander Heiden, O. Iliopoulos, and G. Stephanopoulos Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia Nature 481 2011 380 384
29. J. Xia, Z. Wu, C. Yu, W. He, H. Zheng, Y. He, W. Jian, L. Chen, L. Zhang, and W. Li miR-124 inhibits cell proliferation in gastric cancer through down-regulation of SPHK1 J. Pathol. 227 2012 470 480
30. M. Niyazi, I. Niyazi, and C. Belka Counting colonies of clonogenic assays by using densitometric software Radiat. Oncol. 2 2007 4
31. S.G. Lee, Z.Z. Su, L. Emdad, D. Sarkar, and P.B. Fisher Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc Proc. Natl. Acad. Sci. USA 14 2006 17390 17395
32. S.G. Lee, H.Y. Jeon, Z.Z. Su, J.E. Richards, N. Vozhilla, D. Sarkar, T. Van Maerken, and P.B. Fisher Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma Oncogene 28 2009 2476 2484
33. B.K. Yoo, L. Emdad, Z.Z. Su, A. Villanueva, D.Y. Chiang, N.D. Mukhopadhyay, A.S. Mills, S. Waxman, R.A. Fisher, J.M. Llovet, P.B. Fisher, and D. Sarkar Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression J. Clin. Invest. 119 2009 465 477
34. D.M. Kochanek, and D.G. Wells CPEB1 regulates the expression of MTDH/AEG-1 and glioblastoma cell migration Mol. Cancer Res. 11 2013 149 160
35. Y. Yang, J. Wu, H. Guan, J. Cai, L. Fang, J. Li, and M. Li MiR-136 promotes apoptosis of glioma cells by targeting AEG-1 and Bcl-2 FEBS Lett. 586 20 2012 3608 3612