Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets

PLoS Genetics

Volumn 10, Issue 11, 2014, Pages

  Olsson, Anders H ^a   Volkov, Petr ^a   Bacos, Karl ^a   Dayeh, Tasnim ^a   Hall, Elin ^a   Nilsson, Emma A ^a   Ladenvall, Claes ^a   Rönn, Tina ^a   Ling, Charlotte ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE T1; GROWTH FACTOR RECEPTOR BOUND PROTEIN 10; HLA DQA1 ANTIGEN; INSULIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; MESSENGER RNA; TRANSCRIPTION FACTOR PDX 1; GLUTATHIONE S-TRANSFERASE T1; GLUTATHIONE TRANSFERASE; GPX7 PROTEIN, HUMAN; PEROXIDASE; SORTING NEXIN;

ADCY5 GENE; ARTICLE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; CPG ISLAND; DIABETES MELLITUS; DNA METHYLATION; EPIGENETICS; FOLLOW UP; GENE; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GPX7 GENE; GRB10 GENE; GSTT1 GENE; HLA DQA1 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; INS GENE; INSULIN RELEASE; KCNJ11 GENE; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PDX1 GENE; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; SNX19 GENE; TRANSCRIPTION INITIATION SITE; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOLOGY; SECRETION (PROCESS);

DIABETES MELLITUS, TYPE 2; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; GENOME-WIDE ASSOCIATION STUDY; GLUTATHIONE TRANSFERASE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; PEROXIDASES; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; RNA, MESSENGER; SORTING NEXINS;

EID: 84912105627     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004735     Document Type: Article

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