Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion

PLoS Genetics

Volumn 10, Issue 3, 2014, Pages

  Dayeh, Tasnim ^a   Volkov, Petr ^a   Salö, Sofia ^a   Hall, Elin ^a   Nilsson, Emma ^a   Olsson, Anders H ^a   Kirkpatrick, Clare L ^b   Wollheim, Claes B ^b   Eliasson, Lena ^a   Rönn, Tina ^a   Bacos, Karl ^a   Ling, Charlotte ^a  

^a LUND UNIVERSITY DIABETES CENTRE   (Sweden)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; GLUCAGON; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45A; HEMOGLOBIN A1C; INSULIN; MESSENGER RNA; POTASSIUM CHANNEL KCNQ1; TRANSCRIPTION FACTOR 7 LIKE 2; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ADULT; AGE; ARTICLE; BODY MASS; CDKN1A GENE; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EXO3L2 GENE; EXOCYTOSIS; FEMALE; FTO GENE; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GLUCAGON RELEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN RELEASE; KCNQ1 GENE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PDE7B GENE; PROMOTER REGION; SEPT9 GENE; TCF7L2 GENE; TRANSCRIPTION INITIATION SITE; TRANSCRIPTOMICS; DISEASE PREDISPOSITION; GENETIC EPIGENESIS; GENETICS; HUMAN GENOME; METABOLISM; PATHOLOGY; SECRETION (PROCESS);

CPG ISLANDS; DIABETES MELLITUS, TYPE 2; DISEASE SUSCEPTIBILITY; DNA METHYLATION; EPIGENESIS, GENETIC; EXOCYTOSIS; GENOME, HUMAN; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; PROMOTER REGIONS, GENETIC;

EID: 84897452599     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004160     Document Type: Article

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