-
1
-
-
84862909349
-
Five years of GWAS discovery
-
Visscher, P.M., Brown, M.A., McCarthy, M.I., Yang, J.(2012).Five years of GWAS discovery. Genet.Am. J. Hum.90,7-24
-
(2012)
Genet.Am. J. Hum
, vol.90
, pp. 7-24
-
-
Visscher, P.M.1
Brown, M.A.2
McCarthy, M.I.3
Yang, J.4
-
2
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff, L.A., Sethupathy, P., Junkins, H.A., Ramos, E.M., Mehta, J.P., Collins, F.S., and Manolio, T.A. (2009). Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc. Natl. Acad. Sci. USA 106, 9362-9367
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
3
-
-
70350724550
-
Population genomics in a disease targeted primary cell model
-
Grundberg, E., Kwan, T., Ge, B., Lam, K.C., Koka, V., Kindmark, A., Mallmin, H., Dias, J., Verlaan, D.J., Ouimet, M., et al. (2009). Population genomics in a disease targeted primary cell model. Genome Res. 19, 1942-1952
-
(2009)
Genome Res
, vol.19
, pp. 1942-1952
-
-
Grundberg, E.1
Kwan, T.2
Ge, B.3
Lam, K.C.4
Koka, V.5
Kindmark, A.6
Mallmin, H.7
Dias, J.8
Verlaan, D.J.9
Ouimet, M.10
-
4
-
-
69949176863
-
Common regulatory variation impacts gene expression in a cell type-dependent manner
-
Dimas, A.S., Deutsch, S., Stranger, B.E., Montgomery, S.B., Borel, C., Attar-Cohen, H., Ingle, C., Beazley, C., Gutierrez Arcelus, M., Sekowska, M., et al. (2009). Common regulatory variation impacts gene expression in a cell type-dependent manner. Science 325, 1246-1250
-
(2009)
Science
, vol.325
, pp. 1246-1250
-
-
Dimas, A.S.1
Deutsch, S.2
Stranger, B.E.3
Montgomery, S.B.4
Borel, C.5
Attar-Cohen, H.6
Ingle, C.7
Beazley, C.8
GutierrezArcelus, M.9
Sekowska, M.10
-
5
-
-
34548805282
-
A genome-wide association study of global gene expression
-
Dixon, A.L., Liang, L., Moffatt, M.F., Chen, W., Heath, S.,Wong, K.C., Taylor, J., Burnett, E., Gut, I., Farrall, M., et al.(2007). A genome-wide association study of global gene expression. Nat. Genet. 39, 1202-1207
-
(2012)
Nat. Genet
, vol.39
, pp. 1202-1207
-
-
Dixon, A.L.1
Liang, L.2
Moffatt, M.F.3
Chen, W.4
Heath, S.5
Wong, K.C.6
Taylor, J.7
Burnett, E.8
Gut, I.9
Farrall, M.10
-
6
-
-
84857111200
-
DNase I sensitivity QTLs are a major determinant of human expression variation
-
Degner, J.F., Pai, A.A., Pique-Regi, R., Veyrieras, J.B., Gaffney,D.J., Pickrell, J.K., De Leon, S., Michelini, K., Lewellen, N.,Crawford, G.E., et al. (2012). DNase I sensitivity QTLs are a major determinant of human expression variation. Nature 482, 390-394
-
(2012)
Nature
, vol.482
, pp. 390-394
-
-
Degner, J.F.1
Pai, A.A.2
Pique-Regi, R.3
Veyrieras, J.B.4
Gaffney, D.J.5
Pickrell, J.K.6
De Leon, S.7
Michelini, K.8
Lewellen, N.9
Crawford, G.E.10
-
7
-
-
84880080558
-
Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci
-
HaemGen Consortium
-
Paul, D.S., Albers, C.A., Rendon, A., Voss, K., Stephens, J., van der Harst, P., Chambers, J.C., Soranzo, N., Ouwehand, W.H.,and Deloukas, P.; HaemGen Consortium. (2013). Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci. Genome Res. 23, 1130-1141
-
(2013)
Genome Res
, vol.23
, pp. 1130-1141
-
-
Paul, D.S.1
Albers, C.A.2
Rendon, A.3
Voss, K.4
Stephens, J.5
Vander Harst, P.6
Chambers, J.C.7
Soranzo, N.8
Ouwehand, W.H.9
Deloukas, P.10
-
8
-
-
84873576566
-
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
-
Liu, Y., Aryee, M.J., Padyukov, L., Fallin, M.D., Hesselberg, E.,Runarsson, A., Reinius, L., Acevedo, N., Taub, M., Ronninger,M., et al. (2013). Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat. Biotechnol. 31, 142-147
-
(2012)
Nat. Biotechnol
, vol.31
, pp. 142-147
-
-
Liu, Y.1
Aryee, M.J.2
Padyukov, L.3
Fallin, M.D.4
Hesselberg, E.5
Runarsson, A.6
Reinius, L.7
Acevedo, N.8
Taub, M.9
Ronninger, M.10
-
9
-
-
84868198427
-
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
-
Kulis, M., Heath, S., Bibikova, M., Queirós, A.C., Navarro, A.,Clot, G., Mart́nez-Trillos, A., Castellano, G., Brun-Heath, I.,Pinyol, M., et al. (2012). Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia. Nat. Genet. 44, 1236-1242
-
(2012)
Nat. Genet
, vol.44
, pp. 1236-1242
-
-
Kulis, M.1
Heath, S.2
Bibikova, M.3
Queirós, A.C.4
Navarro, A.5
Clot, G.6
Martínez-Trillos, A.7
Castellano, G.8
Brun-Heath, I.9
Pinyol, M.10
-
10
-
-
84866871814
-
Multiple Tissue Human Expression Resource (MuTHER)Consortium
-
Mapping cis- and trans-regulatory effects across multiple tissues in twins
-
Grundberg, E., Small, K.S., Hedman, A.K., Nica, A.C., Buil, A.,Keildson, S., Bell, J.T., Yang, T.P., Meduri, E., Barrett, A., et al.;Multiple Tissue Human Expression Resource (MuTHER) Consortium. (2012). Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat. Genet. 44, 1084-1089
-
(2012)
Nat. Genet
, vol.44
, pp. 1084-1089
-
-
Grundberg, E.1
Small, K.S.2
Hedman, A.K.3
Nica, A.C.4
Buil, A.5
Keildson, S.6
Bell, J.T.7
Yang, T.P.8
Meduri, E.9
Barrett, A.10
-
11
-
-
84860572791
-
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population
-
MuTHER Consortium
-
Bell, J.T., Tsai, P.C., Yang, T.P., Pidsley, R., Nisbet, J., Glass, D.,Mangino, M., Zhai, G., Zhang, F., Valdes, A., et al.; MuTHER Consortium. (2012). Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet. 8, e1002629
-
(2012)
PLoS Genet
, vol.8
-
-
Bell, J.T.1
Tsai, P.C.2
Yang, T.P.3
Pidsley, R.4
Nisbet, J.5
Glass, D.6
Mangino, M.7
Zhai, G.8
Zhang, F.9
Valdes, A.10
-
12
-
-
84890166425
-
Role of epigenetics in human aging and longevity: Genome-wide DNA methylation profile in centenarians and centenarians' offspring
-
Gentilini, D., Mari, D., Castaldi, D., Remondini, D., Ogliari,G., Ostan, R., Bucci, L., Sirchia, S.M., Tabano, S., Cavagnini,F., et al. (2013). Role of epigenetics in human aging and longevity: genome-wide DNA methylation profile in centenarians and centenarians' offspring. Age (Dordr.) 35, 1961-1973
-
(2013)
Age (Dordr.)
, vol.35
, pp. 1961-1973
-
-
Gentilini, D.1
Mari, D.2
Castaldi, D.3
Remondini, D.4
Ogliari, G.5
Ostan, R.6
Bucci, L.7
Sirchia, S.M.8
Tabano, S.9
Cavagnini, F.10
-
13
-
-
84859150673
-
Genetic and nongenetic influences during pregnancy on infant global and site specific DNA methylation: Role for folate gene variants and vitamin B12
-
McKay, J.A., Groom, A., Potter, C., Coneyworth, L.J., Ford, D.,Mathers, J.C., and Relton, C.L. (2012). Genetic and nongenetic influences during pregnancy on infant global and site specific DNA methylation: role for folate gene variants and vitamin B12. PLoS ONE 7, e33290
-
(2012)
PLoS ONE 7
-
-
McKay, J.A.1
Groom, A.2
Potter, C.3
Coneyworth, L.J.4
Ford, D.5
Mathers, J.C.6
Relton, C.L.7
-
14
-
-
84867251622
-
450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy
-
Joubert, B.R., Haberg, S.E., Nilsen, R.M., Wang, X., Vollset,S.E., Murphy, S.K., Huang, Z., Hoyo, C., Midttun, O., Cupul-Uicab, L.A., et al. (2012). 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. Environ. Health Perspect. 120,1425-1431
-
(2012)
Environ. Health Perspect
, vol.120
, pp. 1425-1431
-
-
Joubert, B.R.1
Håberg, S.E.2
Nilsen, R.M.3
Wang, X.4
Vollset, S.E.5
Murphy, S.K.6
Huang, Z.7
Hoyo, C.8
Midttun, O.9
Cupul-Uicab, L.A.10
-
15
-
-
79953706343
-
Tobacco-smoking-related differential DNA methylation:27K discovery and replication
-
Breitling, L.P., Yang, R., Korn, B., Burwinkel, B., and Brenner,H. (2011). Tobacco-smoking-related differential DNA methylation:27K discovery and replication. Am. J. Hum. Genet. 88,450-457
-
(2012)
Am. J. Hum. Genet
, vol.120
, pp. 1425-1431
-
-
Breitling, L.P.1
Yang, R.2
Korn, B.3
Burwinkel, B.4
Brenner, H.5
-
16
-
-
46249117780
-
Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation
-
Kerkel, K., Spadola, A., Yuan, E., Kosek, J., Jiang, L., Hod, E., Li,K., Murty, V.V., Schupf, N., Vilain, E., et al. (2008). Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation. Nat.Genet. 40, 904-908
-
(2008)
Nat.Genet
, vol.40
, pp. 904-908
-
-
Kerkel, K.1
Spadola, A.2
Yuan, E.3
Kosek, J.4
Jiang, L.5
Hod, E.6
Li, K.7
Murty, V.V.8
Schupf, N.9
Vilain, E.10
-
17
-
-
77953223693
-
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain
-
Gibbs, J.R., van der Brug, M.P., Hernandez, D.G., Traynor, B.J.,Nalls, M.A., Lai, S.L., Arepalli, S., Dillman, A., Rafferty, I.P.,Troncoso, J., et al. (2010). Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet. 6, e1000952
-
(2010)
PLoS Genet
, vol.6
-
-
Gibbs, J.R.1
Van Der Brug, M.P.2
Hernandez, D.G.3
Traynor, B.J.4
Nalls, M.A.5
Lai, S.L.6
Arepalli, S.7
Dillman, A.8
Rafferty, I.P.9
Troncoso, J.10
-
18
-
-
78651552406
-
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell line
-
Bell, J.T., Pai, A.A., Pickrell, J.K., Gaffney, D.J., Pique-Regi, R.,Degner, J.F., Gilad, Y., and Pritchard, J.K. (2011). DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol. 12, R10
-
(2011)
Genome Biol
, vol.12
-
-
Bell, J.T.1
Pai, A.A.2
Pickrell, J.K.3
Gaffney, D.J.4
Pique-Regi, R.5
Degner, J.F.6
Gilad, Y.7
Pritchard, J.K.8
-
19
-
-
84874217134
-
The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue
-
MolPAGE Consortia
-
Drong, A.W., Nicholson, G., Hedman, A.K., Meduri, E.,Grundberg, E., Small, K.S., Shin, S.Y., Bell, J.T., Karpe, F.,Soranzo, N., et al.; MolPAGE Consortia. (2013). The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue.PLoS ONE 8, e55923
-
(2013)
PLoS ONE 8
-
-
Drong, A.W.1
Nicholson, G.2
Hedman, A.K.3
Meduri, E.4
Grundberg, E.5
Small, K.S.6
Shin, S.Y.7
Bell, J.T.8
Karpe, F.9
Soranzo, N.10
-
20
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22
-
Eckhardt, F., Lewin, J., Cortese, R., Rakyan, V.K., Attwood, J.,Burger, M., Burton, J., Cox, T.V., Davies, R., Down, T.A.,et al. (2006). DNA methylation profiling of human chromosomes 6, 20 and 22. Nat. Genet. 38, 1378-1385
-
(2006)
Nat Genet
, vol.38
, pp. 1378-1385
-
-
Eckhardt, F.1
Lewin, J.2
Cortese, R.3
Rakyan, V.K.4
Attwood, J.5
Burger, M.6
Burton, J.7
Cox, T.V.8
Davies, R.9
Down, T.A.10
-
21
-
-
59149084538
-
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissuespecific CpG island shores
-
Irizarry, R.A., Ladd-Acosta, C., Wen, B., Wu, Z., Montano, C.,Onyango, P., Cui, H., Gabo, K., Rongione, M., Webster, M.,et al. (2009). The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissuespecific CpG island shores. Nat. Genet. 41, 178-186
-
(2009)
Nat. Genet
, vol.41
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
Wu, Z.4
Montano, C.5
Onyango, P.6
Cui, H.7
Gabo, K.8
Rongione, M.9
Webster, M.10
-
22
-
-
80053304450
-
High density DNA methylation array with single CpG site resolutio
-
Bibikova, M., Barnes, B., Tsan, C., Ho, V., Klotzle, B., Le, J.M.,Delano, D., Zhang, L., Schroth, G.P., Gunderson, K.L., et al.(2011). High density DNA methylation array with single CpG site resolution. Genomics 98, 288-295
-
(2011)
Genomics
, vol.98
, pp. 288-295
-
-
Bibikova, M.1
Barnes, B.2
Tsan, C.3
Ho, V.4
Klotzle, B.5
Le, J.M.6
Delano, D.7
Zhang, L.8
Schroth, G.P.9
Gunderson, K.L.10
-
23
-
-
84862263248
-
The NIH Roadmap Epigenomics Program data resource
-
Chadwick, L.H. (2012). The NIH Roadmap Epigenomics Program data resource. Epigenomics 4, 317-324
-
(2012)
Epigenomics
, vol.4
, pp. 317-324
-
-
Chadwick, L.H.1
-
25
-
-
84890135412
-
R: A language and environment for statistical computing (Vienna: R Foundation for Statistical Computin
-
R Development Core Team,3-900051-07-0
-
R Development Core Team. (2010). R: A language and environment for statistical computing (Vienna: R Foundation for Statistical Computing), ISBN 3-900051-07-0. http://www.R-project.org
-
(2010)
ISBN
-
-
-
26
-
-
0036226603
-
BLAT-The BLAST-like alignment tool
-
Kent, W.J. (2002). BLAT-the BLAST-like alignment tool.Genome Res. 12, 656-664
-
(2002)
Genome Res
, vol.12
, pp. 56-664
-
-
Kent, W.J.1
-
27
-
-
84975742565
-
A map of human genome variation from population-scale sequencing
-
1000 Genomes Project Consortium
-
Abecasis, G.R., Altshuler, D., Auton, A., Brooks, L.D., Durbin,R.M., Gibbs, R.A., Hurles, M.E., and McVean, G.A.; 1000 Genomes Project Consortium. (2010). A map of human genome variation from population-scale sequencing. Nature 467, 1061-1073
-
(2010)
Nature
, vol.467
, pp. 1061-1073
-
-
Abecasis, G.R.1
Altshuler, D.2
Auton, A.3
Brooks, L.D.4
Durbin, R.M.5
Gibbs, R.A.6
Hurles, M.E.7
McVean, G.A.8
-
29
-
-
0042424602
-
Statistical significance for genomewide studies
-
Storey, J.D., and Tibshirani, R. (2003). Statistical significance for genomewide studies. Proc. Natl. Acad. Sci. USA 100, 9440-9445
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 9440-9445
-
-
Storey, J.D.1
Tibshirani, R.2
-
30
-
-
10444232639
-
The use of linear mixed models to estimate variance components from data on twin pairs by maximum likelihood
-
Visscher, P.M., Benyamin, B., and White, I. (2004). The use of linear mixed models to estimate variance components from data on twin pairs by maximum likelihood. Twin Res. 7,670-674
-
(2004)
Twin Res
, vol.7
, pp. 670-674
-
-
Visscher, P.M.1
Benyamin, B.2
White, I.3
-
31
-
-
35748941336
-
A genotype calling algorithm for the Illumina BeadArray platform
-
Teo, Y.Y., Inouye, M., Small, K.S., Gwilliam, R., Deloukas, P.,Kwiatkowski, D.P., and Clark, T.G. (2007). A genotype calling algorithm for the Illumina BeadArray platform. Bioinformatics 23, 2741-2746
-
(2007)
Bioinformatics
, vol.23
, pp. 2741-2746
-
-
Teo, Y.Y.1
Inouye, M.2
Small, K.S.3
Gwilliam, R.4
Deloukas, P.5
Kwiatkowski, D.P.6
Clark, T.G.7
-
32
-
-
79957607662
-
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes
-
GIANT Consortium; MAGIC Investigators;DIAGRAM Consortium; MuTHER Consortium
-
Small, K.S., Hedman, A.K., Grundberg, E., Nica, A.C., Thorleifsson,G., Kong, A., Thorsteindottir, U., Shin, S.Y., Richards,H.B., Soranzo, N., et al.; GIANT Consortium; MAGIC Investigators;DIAGRAM Consortium; MuTHER Consortium. (2011).Identification of an imprinted master trans regulator at theKLF14 locus related to multiple metabolic phenotypes. Nat.Genet. 43, 561-564
-
(2011)
Nat.Gene
, vol.43
, pp. 561-564
-
-
Small, K.S.1
Hedman, A.K.2
Grundberg, E.3
Nica, A.C.4
Thorleifsson, G.5
Kong, A.6
Thorsteindottir, U.7
Shin, S.Y.8
Richards, H.B.9
Soranzo, N.10
-
33
-
-
67651222400
-
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
-
Howie, B.N., Donnelly, P., and Marchini, J. (2009). A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 5,e1000529
-
(2009)
PLoS Genet
, vol.5
-
-
Howie, B.N.1
Donnelly, P.2
Marchini, J.3
-
34
-
-
34447324105
-
GenABEL: An R library for genome-wide association analysis
-
Aulchenko, Y.S., Ripke, S., Isaacs, A., and van Duijn, C.M.(2007). GenABEL: an R library for genome-wide association analysis. Bioinformatics 23, 1294-1296
-
(2014)
Bioinformatics
, vol.23
, pp. 1294-1296
-
-
Aulchenko, Y.S.1
Ripke, S.2
Isaacs, A.3
Van Duijn, C.M.4
-
35
-
-
77951152163
-
ProbABEL package for genome-wide association analysis of imputed data
-
Aulchenko, Y.S., Struchalin, M.V., and van Duijn, C.M. (2010).ProbABEL package for genome-wide associationanalysis of imputed data. BMC Bioinformatics 11, 134
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 134
-
-
Aulchenko, Y.S.1
Struchalin, M.V.2
Van Duijn, C.M.3
-
36
-
-
34547628858
-
Family-based association tests for genomewide association scans
-
Am. J. Hum
-
Chen, W.M., and Abecasis, G.R. (2007). Family-based association tests for genomewide association scans. Am. J. Hum. Genet. 81, 913-926
-
(2010)
Genet
, vol.81
, pp. 913-926
-
-
Chen, W.M.1
Abecasis, G.R.2
-
37
-
-
84862832570
-
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
-
Genetic Investigation of ANthropometric Traits (GIANT) Consortium; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
-
Yang, J., Ferreira, T., Morris, A.P., Medland, S.E., Madden, P.A.,Heath, A.C., Martin, N.G., Montgomery, G.W.,Weedon, M.N.,Loos, R.J., et al.; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. (2012). Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nat. Genet. 44, 369-375, S1-S3
-
(2012)
Nat. Genet
, vol.44
-
-
Yang, J.1
Ferreira, T.2
Morris, A.P.3
Medland, S.E.4
Madden, P.A.5
Heath, A.C.6
Martin, N.G.7
Montgomery, G.W.8
Weedon, M.N.9
Loos, R.J.10
-
38
-
-
84864462544
-
A map of the cis-regulatory sequences in the mouse genome
-
Shen, Y., Yue, F., McCleary, D.F., Ye, Z., Edsall, L., Kuan, S.,Wagner, U., Dixon, J., Lee, L., Lobanenkov, V.V., and Ren, B.(2012). A map of the cis-regulatory sequences in the mouse genome. Nature 488, 116-120
-
(2012)
Nature
, vol.488
, pp. 116-120
-
-
Shen, Y.1
Yue, F.2
McCleary, D.F.3
Ye, Z.4
Edsall, L.5
Kuan, S.6
Wagner, U.7
Dixon, J.8
Lee, L.9
Lobanenko, V.V.10
Ren, B.11
-
39
-
-
84868134071
-
Single nucleotide analysis of cytosine methylation by wholegenome shotgun bisulphite sequencing
-
Chapter 21
-
Johnson, M.D., Mueller, M., Game, L., and Aitman, T.J. (2012).Single nucleotide analysis of cytosine methylation by wholegenome shotgun bisulphite sequencing. Curr. Protoc. Mol.Biol. Chapter 21, 23
-
(2012)
Curr. Protoc. Mol.Biol
, pp. 23
-
-
Johnson, M.D.1
Mueller, M.2
Game, L.3
Aitman, T.J.4
-
40
-
-
84856306090
-
Genome-wide DNA methylation profiling using Infinium® assay
-
Bibikova, M., Le, J., Barnes, B., Saedinia-Melnyk, S., Zhou, L.,Shen, R., and Gunderson, K.L. (2009). Genome-wide DNA methylation profiling using Infinium® assay. Epigenomics 1, 177-200
-
(2009)
Epigenomics
, vol.1
, pp. 177-200
-
-
Bibikova, M.1
Le, J.2
Barnes, B.3
Saedinia-Melnyk, S.4
Zhou, L.5
Shen, R.6
Gunderson, K.L.7
-
41
-
-
70649095120
-
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
-
Doi, A., Park, I.H.,Wen, B., Murakami, P., Aryee, M.J., Irizarry,R., Herb, B., Ladd-Acosta, C., Rho, J., Loewer, S., et al. (2009).Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat. Genet. 41,1350-1353
-
(2009)
Nat. Genet
, vol.41
, pp. 1350-1353
-
-
Doi, A.1
Park, I.H.2
Wen, B.3
Murakami, P.4
Aryee, M.J.5
Irizarry, R.6
Herb, B.7
Ladd-Acosta, C.8
Rho, J.9
Loewer, S.10
-
42
-
-
63449103531
-
DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution
-
Zhang, Y., Rohde, C., Tierling, S., Jurkowski, T.P., Bock, C.,Santacruz, D., Ragozin, S., Reinhardt, R., Groth, M., Walter,J., and Jeltsch, A. (2009). DNA methylation analysis of chromosome21 gene promoters at single base pair and single alleleresolution. PLoS Genet. 5, e1000438
-
(2009)
PLoS Genet
, vol.5
-
-
Zhang, Y.1
Rohde, C.2
Tierling, S.3
Jurkowski, T.P.4
Bock, C.5
Santacruz, D.6
Ragozin, S.7
Reinhardt, R.8
Groth, M.9
Walter, J.10
Jeltsch, A.11
-
43
-
-
77649267695
-
Dynamic changes in the human methylome during differentiation
-
Laurent, L.,Wong, E., Li, G., Huynh, T., Tsirigos, A., Ong, C.T.,Low, H.M., Kin Sung, K.W., Rigoutsos, I., Loring, J., and Wei,C.L. (2010). Dynamic changes in the human methylome during differentiation. Genome Res. 20, 320-331
-
(2010)
Genome Res
, vol.20
, pp. 320-331
-
-
Laurent, L.1
Wong, E.2
Li, G.3
Huynh, T.4
Tsirigos, A.5
Ong, C.T.6
Low, H.M.7
Kin Sung, K.W.8
Rigoutsos, I.9
Loring, J.10
Wei, C.L.11
-
44
-
-
64349091471
-
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
-
Ball, M.P., Li, J.B., Gao, Y., Lee, J.H., LeProust, E.M., Park, I.H.,Xie, B., Daley, G.Q., and Church, G.M. (2009). Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat. Biotechnol. 27, 361-368
-
(2009)
Nat. Biotechnol
, vol.27
, pp. 361-368
-
-
Ball, M.P.1
Li, J.B.2
Gao, Y.3
Lee, J.H.4
LeProust, E.M.5
Park, I.H.6
Xie, B.7
Daley, G.Q.8
Church, G.M.9
-
45
-
-
84867145980
-
On the presence and role of human gene-body DNA methylation
-
Jjingo, D., Conley, A.B., Yi, S.V., Lunyak, V.V., and Jordan, I.K.(2012). On the presence and role of human gene-body DNA methylation. Oncotarget 3, 462-474
-
(2012)
Oncotarge
, vol.3
, pp. 462-474
-
-
Jjingo, D.1
Conley, A.B.2
Yi, S.V.3
Lunyak, V.V.4
Jordan, I.K.5
-
46
-
-
40449141957
-
Wholegenome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders
-
Rada-Iglesias, A., Ameur, A., Kapranov, P., Enroth, S., Komorowski,J., Gingeras, T.R., and Wadelius, C. (2008). Wholegenome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders. Genome Res.18, 380-392
-
(2008)
Genome Res
, vol.18
, pp. 380-392
-
-
Rada-Iglesias, A.1
Ameur, A.2
Kapranov, P.3
Enroth, S.4
Komorowski, J.5
Gingeras, T.R.6
Wadelius, C.7
-
47
-
-
4043136572
-
USF1 implicated in the aetiology of familial combined hyperlipidaemia and the metabolic syndrome
-
Shoulders, C.C., and Naoumova, R.P. (2004). USF1 implicated in the aetiology of familial combined hyperlipidaemia and the metabolic syndrome. Trends Mol. Med. 10, 362-365
-
(2004)
Trends Mol. Med
, vol.10
, pp. 362-365
-
-
Shoulders, C.C.1
Naoumova, R.P.2
-
48
-
-
65549104157
-
Histone modifications at human enhancers reflect global cell-type-specific gene expression
-
Heintzman, N.D., Hon, G.C., Hawkins, R.D., Kheradpour, P.,Stark, A., Harp, L.F., Ye, Z., Lee, L.K., Stuart, R.K., Ching,C.W., et al. (2009). Histone modifications at human enhancers reflect global cell-type-specific gene expression.Nature 459, 108-112
-
(2009)
Nature
, vol.459
, pp. 108-112
-
-
Heintzman, N.D.1
Hon, G.C.2
Hawkins, R.D.3
Kheradpour, P.4
Stark, A.5
Harp, L.F.6
Ye, Z.7
Lee, L.K.8
Stuart, R.K.9
Ching, C.W.10
-
49
-
-
78049337953
-
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
-
Speliotes, E.K.,Willer, C.J., Berndt, S.I., Monda, K.L., Thorleifsson,G., Jackson, A.U., Lango Allen, H., Lindgren, C.M., Luan,J., Mägi, R., et al.; MAGIC; Procardis Consortium. (2010). Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat. Genet. 42, 937-948
-
(2010)
Nat. Genet
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
Monda, K.L.4
Thorleifsson, G.5
Jackson, A.U.6
Lango Allen, H.7
Lindgren, C.M.8
Luan, J.9
Mägi, R.10
-
50
-
-
84865712382
-
Annotation of functional variation in personal genomes using RegulomeDB
-
Boyle, A.P., Hong, E.L., Hariharan, M., Cheng, Y., Schaub,M.A., Kasowski, M., Karczewski, K.J., Park, J., Hitz, B.C.,Weng, S., et al. (2012). Annotation of functional variation in personal genomes using RegulomeDB. Genome Res. 22,1790-1797
-
(2012)
Genome Res
, vol.22
, pp. 1790-1797
-
-
Boyle, A.P.1
Hong, E.L.2
Hariharan, M.3
Cheng, Y.4
Schaub, M.A.5
Kasowski, M.6
Karczewski, K.J.7
Park, J.8
Hitz, B.C.9
Weng, S.10
-
51
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
ENCODE Project Consortium
-
ENCODE Project Consortium. (2012). An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
-
52
-
-
84860419950
-
ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity
-
Hurtado del Pozo, C., Vesperinas-García, G., Rubio, M.A.,Corripio-Sánchez, R., Torres-García, A.J., Obregon, M.J., and Calvo, R.M. (2011). ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity. Biochim. Biophys. Acta 1811, 1194-1200
-
(2011)
Biochim. Biophys. Acta
, vol.1811
, pp. 1194-1200
-
-
Hurtado Del Pozo, C.1
Vesperinas-García, G.2
Rubio, M.A.3
Corripio-Sánchez, R.4
Torres-GarcÍa, A.J.5
Obregon, M.J.6
Calvo, R.M.7
-
53
-
-
84872589332
-
Electrical vs manual acupuncture stimulation in a rat model of polycystic ovary syndrome: Different effects on muscle and fat tissue insulin signaling
-
Johansson, J., Mannerås-Holm, L., Shao, R., Olsson, A., Lönn,M., Billig, H., and Stener-Victorin, E. (2013). Electrical vs manual acupuncture stimulation in a rat model of polycystic ovary syndrome: different effects on muscle and fat tissue insulin signaling. PLoS ONE 8, e54357
-
(2013)
PLoS ONE
, vol.8
-
-
Johansson J1
Mannerås-Holm, L.2
Shao, R.3
Olsson, A.4
Lönn, M.5
Billig, H.6
Stener-Victorin, E.7
-
54
-
-
33744805985
-
Genome-wide analysis of mammalian promoter architecture and evolution
-
Carninci, P., Sandelin, A., Lenhard, B., Katayama, S., Shimokawa,K., Ponjavic, J., Semple, C.A., Taylor, M.S., Engström,P.G., Frith, M.C., et al. (2006). Genome-wide analysis of mammalian promoter architecture and evolution. Nat. Genet.38, 626-635
-
(2006)
Nat. Genet
, vol.38
, pp. 626-635
-
-
Carninci, P.1
Sandeli, A.2
Lenhard, B.3
Katayama, S.4
Shimokawa, K.5
Ponjavic, J.6
Semple, C.A.7
Taylor, M.S.8
Engström, P.G.9
Frith, M.C.10
-
55
-
-
78649969065
-
The DNA methylome of human peripheral blood mononuclear cells
-
Li, Y., Zhu, J., Tian, G., Li, N., Li, Q., Ye, M., Zheng, H., Yu, J.,Wu, H., Sun, J., et al. (2010). The DNA methylome of human peripheral blood mononuclear cells. PLoS Biol. 8, e1000533
-
(2010)
PLoS Biol
, vol.8
-
-
Li, Y.1
Zhu, J.2
Tian, G.3
Li, N.4
Li, Q.5
Ye, M.6
Zheng, H.7
Yu, J.8
Wu, H.9
Sun, J.10
-
56
-
-
84864610761
-
Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence
-
Gordon, L., Joo, J.E., Powell, J.E., Ollikainen, M., Novakovic,B., Li, X., Andronikos, R., Cruickshank, M.N., Conneely,K.N., Smith, A.K., et al. (2012). Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence. Genome Res. 22, 1395-1406
-
(2012)
Genome Res
, vol.22
, pp. 1395-1406
-
-
Gordon, L.1
Joo, J.E.2
Powell, J.E.3
Ollikainen, M.4
Novakovic, B.5
Li, X.6
Andronikos, R.7
Cruickshank, M.N.8
Conneely, K.N.9
Smith, A.K.10
-
57
-
-
84857331867
-
Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome
-
Xie, W., Barr, C.L., Kim, A., Yue, F., Lee, A.Y., Eubanks, J.,Dempster, E.L., and Ren, B. (2012). Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome. Cell 148, 816-831
-
(2012)
Cell
, vol.148
, pp. 816-831
-
-
Xie, W.1
Barr, C.L.2
Kim, A.3
Yue, F.4
Lee, A.Y.5
Eubanks, J.6
Dempster, E.L.7
Ren, B.8
-
58
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister, R., Pelizzola, M., Dowen, R.H., Hawkins, R.D., Hon, G.,Tonti-Filippini, J., Nery, J.R., Lee, L., Ye, Z., Ngo, Q.M., et al.(2009). Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 462, 315-322
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
Hawkins, R.D.4
Hon, G.5
Tonti-Filippini, J.6
Nery, J.R.7
Lee, L.8
Ye, Z.9
Ngo, Q.M.10
-
59
-
-
67349190247
-
Linking DNA methylation and histone modification: Patterns and paradigms
-
Cedar, H., and Bergman, Y. (2009). Linking DNA methylation and histone modification: patterns and paradigms. Nat. Rev.Genet. 10, 295-304
-
(2009)
Nat. Rev.Genet
, vol.10
, pp. 295-304
-
-
Cedar, H.1
Bergman, Y.2
-
60
-
-
84865822182
-
Systematic localization of common disease-associated variation in regulatory DNA
-
Maurano, M.T., Humbert, R., Rynes, E., Thurman, R.E.,Haugen, E., Wang, H., Reynolds, A.P., Sandstrom, R., Qu, H.,Brody, J., et al. (2012). Systematic localization of common disease-associated variation in regulatory DNA. Science 337,1190-1195
-
(2012)
Science
, vol.337
, pp. 1190-1195
-
-
Maurano, M.T.1
Humbert, R.2
Rynes, E.3
Thurman, R.E.4
Haugen, E.5
Wang, H.6
Reynolds, A.P.7
Sandstrom, R.8
Qu, H.9
Brody, J.10
-
61
-
-
79955583542
-
Mapping and analysis of chromatin statedynamics in nine human cell types
-
Ernst, J., Kheradpour, P., Mikkelsen, T.S., Shoresh, N., Ward,L.D., Epstein, C.B., Zhang, X., Wang, L., Issner, R., Coyne,M., et al. (2011). Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473, 43-49
-
(2011)
Nature
, vol.473
, pp. 43-49
-
-
Ernst, J.1
Kheradpour, P.2
Mikkelsen, T.S.3
Shoresh, N.4
Ward, L.D.5
Epstein, C.B.6
Zhang, X.7
Wang, L.8
Issner, R.9
Coyne, M.10
|