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Volumn 110, Issue 44, 2013, Pages 17921-17926

Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL SPECIFICITY; CELL TYPE; CHROMATIN STRUCTURE; ENHANCER REGION; GENE CONTROL; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEOTIDE SEQUENCE; PANCREAS ISLET; PRIORITY JOURNAL; QUANTITATIVE TRAIT; REPORTER GENE;

EID: 84887072795     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1317023110     Document Type: Article
Times cited : (538)

References (33)
  • 1
    • 78650304236 scopus 로고    scopus 로고
    • Charting histone modifications and the functional organization of mammalian genomes
    • Zhou VW, Goren A, Bernstein BE (2011) Charting histone modifications and the functional organization of mammalian genomes. Nat Rev Genet 12(1):7-18.
    • (2011) Nat Rev Genet , vol.12 , Issue.1 , pp. 7-18
    • Zhou, V.W.1    Goren, A.2    Bernstein, B.E.3
  • 2
    • 79955583542 scopus 로고    scopus 로고
    • Mapping and analysis of chromatin state dynamics in nine human cell types
    • Ernst J, et al. (2011) Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473(7345):43-49.
    • (2011) Nature , vol.473 , Issue.7345 , pp. 43-49
    • Ernst, J.1
  • 3
    • 78650747491 scopus 로고    scopus 로고
    • Discovery and characterization of chromatin states for systematic annotation of the human genome
    • Ernst J, Kellis M (2010) Discovery and characterization of chromatin states for systematic annotation of the human genome. Nat Biotechnol 28(8):817-825.
    • (2010) Nat Biotechnol , vol.28 , Issue.8 , pp. 817-825
    • Ernst, J.1    Kellis, M.2
  • 4
    • 84857707318 scopus 로고    scopus 로고
    • ChromHMM: Automating chromatin-state discovery and characterization
    • Ernst J, Kellis M (2012) ChromHMM: Automating chromatin-state discovery and characterization. Nat Methods 9(3):215-216.
    • (2012) Nat Methods , vol.9 , Issue.3 , pp. 215-216
    • Ernst, J.1    Kellis, M.2
  • 5
    • 84862785201 scopus 로고    scopus 로고
    • Unsupervised pattern discovery in human chromatin structure through genomic segmentation
    • Hoffman MM, et al. (2012) Unsupervised pattern discovery in human chromatin structure through genomic segmentation. Nat Methods 9(5):473-476.
    • (2012) Nat Methods , vol.9 , Issue.5 , pp. 473-476
    • Hoffman, M.M.1
  • 6
    • 84875448918 scopus 로고    scopus 로고
    • Integrative annotation of chromatin elements from ENCODE data
    • Hoffman MM, et al. (2013) Integrative annotation of chromatin elements from ENCODE data. Nucleic Acids Res 41(2):827-841.
    • (2013) Nucleic Acids Res , vol.41 , Issue.2 , pp. 827-841
    • Hoffman, M.M.1
  • 7
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • ENCODE Project Consortium
    • Bernstein BE, et al.; ENCODE Project Consortium (2012) An integrated encyclopedia of DNA elements in the human genome. Nature 489(7414):57-74.
    • (2012) Nature , vol.489 , Issue.7414 , pp. 57-74
    • Bernstein, B.E.1
  • 9
    • 78049446282 scopus 로고    scopus 로고
    • Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci
    • NISC Comparative Sequencing Program
    • Stitzel ML, et al.; NISC Comparative Sequencing Program (2010) Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci. Cell Metab 12(5):443-455.
    • (2010) Cell Metab , vol.12 , Issue.5 , pp. 443-455
    • Stitzel, M.L.1
  • 10
    • 79955550445 scopus 로고    scopus 로고
    • A user's guide to the encyclopedia of DNA elements (ENCODE)
    • ENCODE Project Consortium
    • ENCODE Project Consortium (2011) A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol 9:e1001046.
    • (2011) PLoS Biol , vol.9
  • 11
    • 84865777819 scopus 로고    scopus 로고
    • ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
    • Landt SG, et al. (2012) ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Res 22(9):1813-1831.
    • (2012) Genome Res , vol.22 , Issue.9 , pp. 1813-1831
    • Landt, S.G.1
  • 12
    • 0023663887 scopus 로고
    • Position-independent, high-level expression of the human beta-globin gene in transgenic mice
    • Grosveld F, van Assendelft GB, Greaves DR, Kollias G (1987) Position-independent, high-level expression of the human beta-globin gene in transgenic mice. Cell 51(6): 975-985.
    • (1987) Cell , vol.51 , Issue.6 , pp. 975-985
    • Grosveld, F.1    Van Assendelft, G.B.2    Greaves, D.R.3    Kollias, G.4
  • 13
    • 84865800494 scopus 로고    scopus 로고
    • The long-range interaction landscape of gene promoters
    • Sanyal A, Lajoie BR, Jain G, Dekker J (2012) The long-range interaction landscape of gene promoters. Nature 489(7414):109-113.
    • (2012) Nature , vol.489 , Issue.7414 , pp. 109-113
    • Sanyal, A.1    Lajoie, B.R.2    Jain, G.3    Dekker, J.4
  • 15
    • 84879208137 scopus 로고    scopus 로고
    • Cohesin at active genes: A unifying theme for cohesin and gene expression from model organisms to humans
    • Dorsett D, Merkenschlager M (2013) Cohesin at active genes: A unifying theme for cohesin and gene expression from model organisms to humans. Curr Opin Cell Biol 25(3):327-333.
    • (2013) Curr Opin Cell Biol , vol.25 , Issue.3 , pp. 327-333
    • Dorsett, D.1    Merkenschlager, M.2
  • 16
    • 77951836691 scopus 로고    scopus 로고
    • A CTCF-independent role for cohesin in tissue-specific transcription
    • Schmidt D, et al. (2010) A CTCF-independent role for cohesin in tissue-specific transcription. Genome Res 20(5):578-588.
    • (2010) Genome Res , vol.20 , Issue.5 , pp. 578-588
    • Schmidt, D.1
  • 17
    • 84882738244 scopus 로고    scopus 로고
    • Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites
    • Yan J, et al. (2013) Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites. Cell 154(4):801-813.
    • (2013) Cell , vol.154 , Issue.4 , pp. 801-813
    • Yan, J.1
  • 18
    • 77955499945 scopus 로고    scopus 로고
    • From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
    • Musunuru K, et al. (2010) From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature 466(7307):714-719.
    • (2010) Nature , vol.466 , Issue.7307 , pp. 714-719
    • Musunuru, K.1
  • 19
    • 68149170044 scopus 로고    scopus 로고
    • The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling
    • Tuupanen S, et al. (2009) The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling. Nat Genet 41(8):885-890.
    • (2009) Nat Genet , vol.41 , Issue.8 , pp. 885-890
    • Tuupanen, S.1
  • 20
    • 84870674626 scopus 로고    scopus 로고
    • Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors
    • Sur IK, et al. (2012) Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors. Science 338(6112):1360-1363.
    • (2012) Science , vol.338 , Issue.6112 , pp. 1360-1363
    • Sur, I.K.1
  • 21
    • 84862908850 scopus 로고    scopus 로고
    • Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation
    • Li G, et al. (2012) Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. Cell 148(1-2):84-98.
    • (2012) Cell , vol.148 , Issue.1-2 , pp. 84-98
    • Li, G.1
  • 22
    • 12344269924 scopus 로고    scopus 로고
    • GO:TermFinder-Open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes
    • Boyle EI, et al. (2004) GO:TermFinder-Open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes. Bioinformatics 20(18):3710-3715.
    • (2004) Bioinformatics , vol.20 , Issue.18 , pp. 3710-3715
    • Boyle, E.I.1
  • 23
    • 49949096013 scopus 로고    scopus 로고
    • Gene Ontology term overlap as a measure of gene functional similarity
    • Mistry M, Pavlidis P (2008) Gene Ontology term overlap as a measure of gene functional similarity. BMC Bioinformatics 9:327.
    • (2008) BMC Bioinformatics , vol.9 , pp. 327
    • Mistry, M.1    Pavlidis, P.2
  • 24
    • 84865822182 scopus 로고    scopus 로고
    • Systematic localization of common disease-associated variation in regulatory DNA
    • Maurano MT, et al. (2012) Systematic localization of common disease-associated variation in regulatory DNA. Science 337(6099):1190-1195.
    • (2012) Science , vol.337 , Issue.6099 , pp. 1190-1195
    • Maurano, M.T.1
  • 25
    • 84873086126 scopus 로고    scopus 로고
    • Chromatin marks identify critical cell types for fine mapping complex trait variants
    • Trynka G, et al. (2013) Chromatin marks identify critical cell types for fine mapping complex trait variants. Nat Genet 45(2):124-130.
    • (2013) Nat Genet , vol.45 , Issue.2 , pp. 124-130
    • Trynka, G.1
  • 26
    • 84869436774 scopus 로고    scopus 로고
    • Interpreting noncoding genetic variation in complex traits and human disease
    • Ward LD, Kellis M (2012) Interpreting noncoding genetic variation in complex traits and human disease. Nat Biotechnol 30(11):1095-1106.
    • (2012) Nat Biotechnol , vol.30 , Issue.11 , pp. 1095-1106
    • Ward, L.D.1    Kellis, M.2
  • 27
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, et al. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125(2):315-326.
    • (2006) Cell , vol.125 , Issue.2 , pp. 315-326
    • Bernstein, B.E.1
  • 28
    • 84873310426 scopus 로고    scopus 로고
    • Genome-wide chromatin state transitions associated with developmental and environmental cues
    • Zhu J, et al. (2013) Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell 152(3):642-654.
    • (2013) Cell , vol.152 , Issue.3 , pp. 642-654
    • Zhu, J.1
  • 29
    • 78650453629 scopus 로고    scopus 로고
    • DNA search efficiency is modulated by charge composition and distribution in the intrinsically disordered tail
    • Vuzman D, Levy Y (2010) DNA search efficiency is modulated by charge composition and distribution in the intrinsically disordered tail. Proc Natl Acad Sci USA 107(49): 21004-21009.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.49 , pp. 21004-21009
    • Vuzman, D.1    Levy, Y.2
  • 30
    • 84876216563 scopus 로고    scopus 로고
    • Master transcription factors and mediator establish superenhancers at key cell identity genes
    • Whyte WA, et al. (2013) Master transcription factors and mediator establish superenhancers at key cell identity genes. Cell 153(2):307-319.
    • (2013) Cell , vol.153 , Issue.2 , pp. 307-319
    • Whyte, W.A.1
  • 31
    • 84876222028 scopus 로고    scopus 로고
    • Selective inhibition of tumor oncogenes by disruption of superenhancers
    • Lovén J, et al. (2013) Selective inhibition of tumor oncogenes by disruption of superenhancers. Cell 153(2):320-334.
    • (2013) Cell , vol.153 , Issue.2 , pp. 320-334
    • Lovén, J.1
  • 32
    • 84861335436 scopus 로고    scopus 로고
    • Pharmacogene regulatory elements: From discovery to applications
    • Smith RP, Lam ET, Markova S, Yee SW, Ahituv N (2012) Pharmacogene regulatory elements: From discovery to applications. Genome Med 4(5):45.
    • (2012) Genome Med , vol.4 , Issue.5 , pp. 45
    • Smith, R.P.1    Lam, E.T.2    Markova, S.3    Yee, S.W.4    Ahituv, N.5
  • 33
    • 70350453755 scopus 로고    scopus 로고
    • The human insulin gene is part of a large open chromatin domain specific for human islets
    • Mutskov V, Felsenfeld G (2009) The human insulin gene is part of a large open chromatin domain specific for human islets. Proc Natl Acad Sci USA 106(41):17419-17424.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.41 , pp. 17419-17424
    • Mutskov, V.1    Felsenfeld, G.2


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