-
1
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
DOI 10.1126/science.1071924
-
Chen G, Goeddel DV (2002) TNF-R1 signaling: A beautiful pathway. Science 296: 1634-1635. (Pubitemid 34579145)
-
(2002)
Science
, vol.296
, Issue.5573
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
3
-
-
0027420579
-
Tumor necrosis factor: An updated review of its biology
-
Tracey KJ, Cerami A (1993) Tumor necrosis factor: An updated review of its biology. Crit Care Med 21(10, Suppl):S415-S422. (Pubitemid 23304331)
-
(1993)
Critical Care Medicine
, vol.21
, Issue.10 SUPPL.
-
-
Tracey, K.J.1
Cerami, A.2
-
4
-
-
85047692516
-
Signalling pathways of the TNF superfamily: A double-edged sword
-
Aggarwal BB (2003) Signalling pathways of the TNF superfamily: A double-edged sword. Nat Rev Immunol 3:745-756.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 745-756
-
-
Aggarwal, B.B.1
-
5
-
-
0033576675
-
More than one way to die: Apoptosis, necrosis and reactive oxygen damage
-
Fiers W, Beyaert R, Declercq W, Vandenabeele P (1999) More than one way to die: Apoptosis, necrosis and reactive oxygen damage. Oncogene 18:7719-7730. (Pubitemid 30052757)
-
(1999)
Oncogene
, vol.18
, Issue.54
, pp. 7719-7730
-
-
Fiers, W.1
Beyaert, R.2
Declercq, W.3
Vandenabeele, P.4
-
6
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
KarinM, LinA(2002) NF-kappaB at the crossroads of life and death. Nat Immunol 3:221-227.
-
(2002)
Nat Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
7
-
-
34249820757
-
TNF-Induced Activation of the Nox1 NADPH Oxidase and Its Role in the Induction of Necrotic Cell Death
-
DOI 10.1016/j.molcel.2007.04.021, PII S1097276507002584
-
Kim YS, Morgan MJ, Choksi S, Liu ZG (2007) TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death. Mol Cell 26: 675-687. (Pubitemid 46856240)
-
(2007)
Molecular Cell
, vol.26
, Issue.5
, pp. 675-687
-
-
Kim, Y.-S.1
Morgan, M.J.2
Choksi, S.3
Liu, Z.-g.4
-
8
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
DOI 10.1016/S0092-8674(03)00521-X
-
Micheau O, Tschopp J (2003) Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114:181-190. (Pubitemid 36936912)
-
(2003)
Cell
, vol.114
, Issue.2
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
9
-
-
33749178260
-
Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
-
DOI 10.1016/j.bbabio.2006.06.014, PII S000527280600212X, Mitochondria: from Molecular Insight to Physiology and Pathology
-
Festjens N, Vanden Berghe T, Vandenabeele P (2006) Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response. Biochim Biophys Acta 1757:1371-1387. (Pubitemid 44472550)
-
(2006)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1757
, Issue.9-10
, pp. 1371-1387
-
-
Festjens, N.1
Vanden, B.T.2
Vandenabeele, P.3
-
10
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho YS, et al. (2009) Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137:1112-1123.
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
-
12
-
-
0242656497
-
Death receptor-induced cell killing
-
Thorburn A (2004) Death receptor-induced cell killing. Cell Signal 16:139-144.
-
(2004)
Cell Signal
, vol.16
, pp. 139-144
-
-
Thorburn, A.1
-
13
-
-
57649167477
-
Necroptosis: A specialized pathway of programmed necrosis
-
Galluzzi L, Kroemer G (2008) Necroptosis: A specialized pathway of programmed necrosis. Cell 135:1161-1163.
-
(2008)
Cell
, vol.135
, pp. 1161-1163
-
-
Galluzzi, L.1
Kroemer, G.2
-
14
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev A, et al. (2005) Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 1:112-119.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 112-119
-
-
Degterev, A.1
-
15
-
-
0029090167
-
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity
-
Goossens V, Grooten J, De Vos K, Fiers W (1995) Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity. Proc Natl Acad Sci USA 92:8115-8119.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8115-8119
-
-
Goossens, V.1
Grooten, J.2
De Vos, K.3
Fiers, W.4
-
16
-
-
0042525938
-
NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
-
DOI 10.1093/emboj/cdg379
-
Sakon S, et al. (2003) NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. EMBO J 22:3898-3909. (Pubitemid 36975716)
-
(2003)
EMBO Journal
, vol.22
, Issue.15
, pp. 3898-3909
-
-
Sakon, S.1
Xue, X.2
Takekawa, M.3
Sasazuki, T.4
Okazaki, T.5
Kojima, Y.6
Piao, J.-H.7
Yagita, H.8
Okumura, K.9
Doi, T.10
Nakano, H.11
-
17
-
-
1642299768
-
Tumor Necrosis Factor-induced Nonapoptotic Cell Death Requires Receptor-interacting Protein-mediated Cellular Reactive Oxygen Species Accumulation
-
DOI 10.1074/jbc.M313141200
-
Lin Y, et al. (2004) Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation. J Biol Chem 279:10822-10828. (Pubitemid 38372695)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.11
, pp. 10822-10828
-
-
Lin, Y.1
Choksi, S.2
Shen, H.-M.3
Yang, Q.-F.4
Hur, G.M.5
Kim, Y.S.6
Tran, J.H.7
Nedospasov, S.A.8
Liu, Z.-G.9
-
18
-
-
10044265209
-
JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species
-
DOI 10.1101/gad.1223004
-
Ventura JJ, Cogswell P, Flavell RA, Baldwin AS, Jr., Davis RJ (2004) JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species. Genes Dev 18:2905-2915. (Pubitemid 39602309)
-
(2004)
Genes and Development
, vol.18
, Issue.23
, pp. 2905-2915
-
-
Ventura, J.-J.1
Cogswell, P.2
Flavell, R.A.3
Baldwin Jr., A.S.4
Davis, R.J.5
-
19
-
-
14844327760
-
Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
DOI 10.1016/j.cell.2004.12.041
-
Kamata H, et al. (2005) Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120: 649-661. (Pubitemid 40343077)
-
(2005)
Cell
, vol.120
, Issue.5
, pp. 649-661
-
-
Kamata, H.1
Honda, S.-I.2
Maeda, S.3
Chang, L.4
Hirata, H.5
Karin, M.6
-
20
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler N, et al. (2000) Fas triggers an alternative, caspase-8- independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 1:489-495.
-
(2000)
Nat Immunol
, vol.1
, pp. 489-495
-
-
Holler, N.1
-
21
-
-
0033214236
-
Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis
-
DOI 10.1101/gad.13.19.2514
-
Lin Y, Devin A, Rodriguez Y, Liu ZG (1999) Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 13:2514-2526. (Pubitemid 29489643)
-
(1999)
Genes and Development
, vol.13
, Issue.19
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.-G.4
-
22
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang DW, et al. (2009) RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325:332-336.
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
-
23
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
He S, et al. (2009) Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 137:1100-1111.
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
-
24
-
-
66149091940
-
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene
-
Luo J, et al. (2009) A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell 137:835-848.
-
(2009)
Cell
, vol.137
, pp. 835-848
-
-
Luo, J.1
-
25
-
-
84859469205
-
Use of mixed lineage like kinase polypeptides (mlkl polypeptides) in cancer therapy
-
International Patent A61K38/45; C12N9/12
-
Mollenhauer J, et al. (2010) Use of mixed lineage like kinase polypeptides (mlkl polypeptides) in cancer therapy. International Patent A61K38/45; C12N9/12.
-
(2010)
-
-
Mollenhauer, J.1
-
26
-
-
33344477350
-
Chemical genetic analysis of the time course of signal transduction by JNK
-
Ventura JJ, et al. (2006) Chemical genetic analysis of the time course of signal transduction by JNK. Mol Cell 21:701-710.
-
(2006)
Mol Cell
, vol.21
, pp. 701-710
-
-
Ventura, J.J.1
-
27
-
-
84862907788
-
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
-
Sun L, et al. (2011) Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 148:213-227.
-
(2011)
Cell
, vol.148
, pp. 213-227
-
-
Sun, L.1
|