Expression of X-linked inhibitor of apoptosis protein in human colorectal cancer and its correlation with prognosis

Journal of Surgical Oncology

Volumn 100, Issue 8, 2009, Pages 708-712

  Xiang, Guoan ^a   Wen, Xiaomin ^b   Wang, Hanning ^a   Chen, Kaiyun ^a   Liu, Hao ^b  

^a GUANGDONG SECOND PROVINCIAL GENERAL HOSPITAL   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Colorectal cancer; Disease free survival; Immunohistochemistry; Overall survival; X linked inhibitor of apoptosis protein

Indexed keywords

X LINKED INHIBITOR OF APOPTOSIS;

ADULT; AGED; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INVASION; CANCER STAGING; CARCINOGENICITY; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE FREE SURVIVAL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM CELL; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; TUMOR DIFFERENTIATION; X CHROMOSOME LINKAGE;

ADULT; AGED; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PROGNOSIS; RNA, MESSENGER; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 73449115334     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.21408     Document Type: Article

References (23)

1. Jemal A, Siegel R, Ward E, et al.: Cancer statistics, 2006. CA Cancer J Clin 2006;56:106-130.
2. Weitz J, Koch M, Debus J, et al.: Colorectal cancer. Lancet 2005;65:153-165.
3. Katoh H, Yamashita K, Satoh T, et al.: Validation of prognostic impact of preoperative carcinoembryonic antigen (CEA) in Dukes' C colorectal cancer. A prospective study. Anticancer Res 2008;28:1933-1941.
4. Deveraux QL, Takahashi R, Salvesen GS, et al.: X-linked IAP is a direct inhibitor of cell death proteases. Nature 1997;388:300-304.
5. Li Y, Jian Z, Xia K, et al.: XIAP is related to the chemoresistance and inhibited its expression by RNA interference sensitize pancreatic carcinoma cells to chemotherapeutics. Pancreas 2006;32:288-296.
6. Holcik M, Yeh C, Korneluk RG, et al.: Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death. Oncogene 2000;19:4174-4177.
7. Liston P, Young SS, Mackenzie AE, et al.: Life and death decisions: The role of the IAPs in modulating programmed cell death. Apoptosis 2004;2:423-441.
8. Lin JH, Deng G, Huang Q, et al.: KIAP, a novel member of the inhibitor of apoptosis protein family. Biochem Biophys Res Commun 2000;279:820-831.
9. Kasof GM, Gomes BC: Livin, a novel inhibitor of apoptosis protein family member. J Biol Chem 2001;276:3238-3246.
10. Holcik M, Gibson H, Korneluk RG: XIAP: Apoptotic brake and promising therapeutic target. Apoptosis 2001;6:253-261.
11. Schimmer AD, Dalili S, Batey RA, et al.: Targeting the XIAP for the treatment of malignancy. Cell Death Differ 2006;13:179-188.
12. Dean EJ, Ranson M, Blackhall F, et al.: X-linked inhibitor of apoptosis protein as a therapeutic target. Expert Opin Ther Targets 2007;11:1459-1471.
13. Augello C, Caruso L, Maggioni M, et al.: Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma. BMC Cancer 2009;9:125.
14. Liu J, Li M, Xia S: Expression and clinical significance of antiapoptosis gene XIAP in prostate cancer. Zhonghua Nan Ke Xue 2004;10:832-835.
15. Nagi C, Xiao GQ, Li G, et al.: Immunohistochemical detection of X-linked inhibitor of apoptosis in head and neck squamous cell carcinoma. Ann Diagn Pathol 2007;11:402-406.
16. Testa U, Riccioni R: Deregulation of apoptosis in acute myeloid leukemia. Haematologica 2007;92:81-94.
17. Burstein DE, Idrees MT, Li G, et al.: Immunohistochemical detection of the X-linked inhibitor of apoptosis protein (XIAP) in cervical squamous intraepithelial neoplasia and squamous carcinoma. Ann Diagn Pathol 2008;12:85-89.
18. Tamm I, Richter S, Oltersdorf D, et al.: High expression levels of x-linked inhibitor of apoptosis protein and survivin correlate with poor overall survival in childhood de novo acute myeloid leukemia. Clin Cancer Res 2004;10:3737-3744.
19. Emanuel PO, Phelps RG, Mudgil A, et al.: Immunohistochemical detection of XIAP in melanoma. J Cutan Pathol 2008;35:292-297.
20. Mizutani Y, Nakanishi H, Li YN, et al.: Overexpression of XIAP expression in renal cell carcinoma predicts a worse prognosis. Int J Oncol 2007;30:919-925.
21. Amantana A, London CA, Iversen PL, et al.: X-linked inhibitor of apoptosis protein inhibition induces apoptosis and enhances chemotherapy sensitivity in human prostate cancer cells. Mol Cancer Ther 2004;3:699-707.
22. Connolly K, Mitter R, Muir M, et al.: Stable XIAP knockdown clones of HCT116 colon cancer cells are more sensitive to TRAIL, taxanes and irradiation in vitro. Cancer Chemother Pharmacol 2009;64:307-316.
23. Vogler M, Walczak H, Stadel D, et al.: Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma. Cancer Res 2009;69:2425-2434.