-
2
-
-
0034691130
-
Structure-based discovery of an organic compound that binds bcl-2 protein and induces apoptosis of tumor cells
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7124-7129
-
-
Wang, J.L.1
-
8
-
-
0031907428
-
Bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
-
(1998)
Nature Med.
, vol.4
, pp. 232-234
-
-
Jansen, B.1
-
10
-
-
0034015672
-
Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 1812-1823
-
-
Waters, J.S.1
-
11
-
-
0034096268
-
A novel bispecific antisense oligonucleotide inhibiting both bcl-2 and bcl-xL expression efficiently induces apoptosis in tumor cells
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2547-2555
-
-
Zangemeister-Wittke, U.1
-
14
-
-
0032697242
-
Cholangiocarcinomas express Fas ligand and disable the Fas receptor
-
(1999)
Hepatology
, vol.30
, pp. 1398-1404
-
-
Que, F.G.1
-
18
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
-
19
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
-
20
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
-
22
-
-
0030970013
-
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
-
(1997)
Nature
, vol.386
, pp. 517-521
-
-
Thome, M.1
-
23
-
-
7344220967
-
Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex
-
(1998)
Cell Death Differ.
, vol.5
, pp. 271-288
-
-
Rasper, D.M.1
-
25
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
(1999)
Nature Med.
, vol.5
, pp. 157-163
-
-
Walczak, H.1
-
31
-
-
0034732258
-
Wild-type p53 transactivates the KILLER/DRS gene through an intronic sequence-specific DNA-binding site
-
(2000)
Oncogene
, vol.19
, pp. 1735-1743
-
-
Takimoto, R.1
El-Deiry, W.S.2
-
33
-
-
0034026719
-
Steering anti-cancer drugs away from the TRAIL
-
(2000)
Nature Med.
, vol.6
, pp. 502-503
-
-
Nagata, S.1
-
34
-
-
0034022160
-
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
-
(2000)
Nature Med.
, vol.6
, pp. 564-567
-
-
Jo, M.1
-
35
-
-
0034142219
-
A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL
-
(2000)
Biochemistry
, vol.39
, pp. 633-640
-
-
Hymowitz, S.G.1
-
36
-
-
0033212968
-
Triggering cell death: The crystal structure of Apo2L/TRAIL in a complex with death receptor 5
-
(1999)
Mol. Cell
, vol.4
, pp. 563-571
-
-
Hymowitz, S.G.1
-
37
-
-
0009530192
-
Human ICE/CED-3 protease nomenclature
-
(1996)
Cell
, vol.87
, pp. 171
-
-
Alnemri, E.S.1
-
38
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1β processing monocytes
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
-
39
-
-
0026517239
-
Molecular cloning of the interleukin-1β converting enzyme
-
(1992)
Science
, vol.256
, pp. 97-100
-
-
Cerretti, D.P.1
-
41
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
-
42
-
-
0029956641
-
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
-
(1996)
Nature
, vol.384
, pp. 368-372
-
-
Kuida, K.1
-
45
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.A.1
-
47
-
-
0033005752
-
A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis
-
(1999)
FASEB J.
, vol.13
, pp. 253-261
-
-
Cursio, R.1
-
49
-
-
0032846978
-
A specific inhibitor of apoptosis decreases tissue injury after intestinal ischemia-reperfusion in mice
-
(1999)
J. Vasc. Surg.
, vol.30
, pp. 752-760
-
-
Farber, A.1
-
50
-
-
0032743421
-
Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 541-549
-
-
Daemen, M.A.1
-
52
-
-
0030804272
-
Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury
-
(1997)
J. Neurosci.
, vol.17
, pp. 7415-7424
-
-
Yakovlev, A.G.1
-
54
-
-
0034647003
-
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
-
(2000)
Science
, vol.288
, pp. 335-339
-
-
Li, M.1
-
55
-
-
0033008216
-
Caspase inhibition reduces apoptosis and increases survival of nigral transplants
-
(1999)
Nature Med.
, vol.5
, pp. 97-100
-
-
Schierle, G.S.1
-
56
-
-
0032977353
-
Neuroprotection by a caspase inhibitor in acute bacterial meningitis
-
(1999)
Nature Med.
, vol.5
, pp. 298-302
-
-
Braun, J.S.1
-
57
-
-
0033276621
-
Peptidomimetic fluoromethylketone rescues mice from lethal endoroxic shock
-
(1999)
Mol. Med.
, vol.5
, pp. 585-594
-
-
Grobmyer, S.R.1
-
59
-
-
0033103523
-
Caspase-8 is required for cell death induced by expanded polyglutamine repeats
-
(1999)
Neuron
, vol.22
, pp. 623-633
-
-
Sanchez, I.1
-
60
-
-
9344227302
-
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
-
(1996)
Nature Genet.
, vol.13
, pp. 442-449
-
-
Goldberg, Y.P.1
-
61
-
-
0033617402
-
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation
-
(1999)
Cell
, vol.97
, pp. 395-406
-
-
Gervais, F.G.1
-
63
-
-
0034717269
-
Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16007-16014
-
-
Lee, D.1
|