E3 ligase activity of XIAP RING domain is required for XIAP-mediated cancer cell migration, but not for its RhoGDI binding activity

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Liu, Jinyi ^a   Zhang, Dongyun ^a   Luo, Wenjing ^b   Yu, Jianxiu ^a   Li, Jingxia ^a   Yu, Yonghui ^a   Zhang, Xinhai ^a   Chen, Jingyuan ^b   Wu, Xue Ru ^a   Huang, Chuanshu ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; F ACTIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE E3; X LINKED INHIBITOR OF APOPTOSIS; CASPASE; GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; UBIQUITIN PROTEIN LIGASE; XIAP PROTEIN, HUMAN;

ACTIN POLYMERIZATION; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CANCER CELL; CANCER INVASION; CELL MIGRATION; CELL MOTILITY; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; POINT MUTATION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; UBIQUITINATION; APOPTOSIS; CELL MOTION; CELL PROLIFERATION; ENZYMOLOGY; GENETICS; METABOLISM; NEOPLASM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; TUMOR CELL CULTURE; TUMOR CELL LINE;

APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; HUMANS; NEOPLASMS; PROTEIN STRUCTURE, TERTIARY; TUMOR CELLS, CULTURED; UBIQUITIN-PROTEIN LIGASES; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84859880440     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035682     Document Type: Article

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