Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis

Neoplasia

Volumn 13, Issue 10, 2011, Pages 971-979

  Laukens, Bram ^a,b,c,d   Jennewein, Claudia ^a   Schenk, Barbara ^d   Vanlangenakker, Nele ^b,c   Schier, Alexander ^a   Cristofanon, Silvia ^d   Zobel, Kerry ^e   Deshayes, Kurt ^e   Vucic, Domagoj ^e   Jeremias, Irmela ^f   Bertrand, Mathieu J M ^b,c   Vandenabeele, Peter ^b,c   Fulda, Simone ^a,d  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c GHENT UNIVERSITY   (Belgium)

^d GOETHE UNIVERSITY   (Germany)

^e GENENTECH INC   (United States)

^f INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; NECROSTATIN 1; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; RECEPTOR INTERACTING PROTEIN 1; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; Z VAD FMK;

APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; NECROPTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

EID: 80054817975     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.11610     Document Type: Article

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