A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells

Oncogene

Volumn 24, Issue 49, 2005, Pages 7381-7388

  Bockbrader, Katrina M ^a   Tan, Mingjia ^a   Sun, Yi ^a  

^a UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

Author keywords

Anticancer drug; Apoptosis; Breast cancer; IAPs; Smac

Indexed keywords

CASPASE 3; ETOPOSIDE; INHIBITOR OF APOPTOSIS PROTEIN; ISOPROTEIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER CELL; CANCER CELL CULTURE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG POTENCY; ENZYME ACTIVATION; FEMALE; GLIOBLASTOMA; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; IC 50; MOLECULAR SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BREAST NEOPLASMS; CASPASE 3; CASPASES; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; ETOPOSIDE; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE GLYCOPROTEINS; MITOCHONDRIAL PROTEINS; MOLECULAR MIMICRY; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

INTRACISTERNAL A-PARTICLES;

EID: 27744526342     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1208888     Document Type: Article

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