메뉴 건너뛰기




Volumn 131, Issue 4, 2007, Pages 682-693

IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

Author keywords

CELLBIO; HUMDISEASE; SIGNALING

Indexed keywords

17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN; BREFELDIN A; CASPASE 8 INHIBITOR; GELDANAMYCIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; X LINKED INHIBITOR OF APOPTOSIS;

EID: 36148954336     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2007.10.037     Document Type: Article
Times cited : (940)

References (35)
  • 2
    • 3142719113 scopus 로고    scopus 로고
    • Requirement of Hsp90 activity for IκB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-κB activation
    • Broemer M., Krappmann D., and Scheidereit C. Requirement of Hsp90 activity for IκB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-κB activation. Oncogene 23 (2004) 5378-5386
    • (2004) Oncogene , vol.23 , pp. 5378-5386
    • Broemer, M.1    Krappmann, D.2    Scheidereit, C.3
  • 3
    • 0034710649 scopus 로고    scopus 로고
    • Structural and biochemical basis of apoptotic activation by Smac/DIABLO
    • Chai J., Du C., Wu J.W., Kyin S., Wang X., and Shi Y. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature 406 (2000) 855-862
    • (2000) Nature , vol.406 , pp. 855-862
    • Chai, J.1    Du, C.2    Wu, J.W.3    Kyin, S.4    Wang, X.5    Shi, Y.6
  • 4
    • 0036187476 scopus 로고    scopus 로고
    • TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90
    • Chen G., Cao P., and Goeddel D.V. TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90. Mol. Cell 9 (2002) 401-410
    • (2002) Mol. Cell , vol.9 , pp. 401-410
    • Chen, G.1    Cao, P.2    Goeddel, D.V.3
  • 9
    • 33645640920 scopus 로고    scopus 로고
    • The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases
    • Eckelman B.P., and Salvesen G.S. The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases. J. Biol. Chem. 281 (2006) 3254-3260
    • (2006) J. Biol. Chem. , vol.281 , pp. 3254-3260
    • Eckelman, B.P.1    Salvesen, G.S.2
  • 10
    • 0036629347 scopus 로고    scopus 로고
    • Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8
    • Fotin-Mleczek M., Henkler F., Samel D., Reichwein M., Hausser A., Parmryd I., Scheurich P., Schmid J.A., and Wajant H. Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8. J. Cell Sci. 115 (2002) 2757-2770
    • (2002) J. Cell Sci. , vol.115 , pp. 2757-2770
    • Fotin-Mleczek, M.1    Henkler, F.2    Samel, D.3    Reichwein, M.4    Hausser, A.5    Parmryd, I.6    Scheurich, P.7    Schmid, J.A.8    Wajant, H.9
  • 11
    • 8444220390 scopus 로고    scopus 로고
    • TRAF2 differentially regulates the canonical and noncanonical pathways of NF-κB activation in mature B cells
    • Grech A.P., Amesbury M., Chan T., Gardam S., Basten A., and Brink R. TRAF2 differentially regulates the canonical and noncanonical pathways of NF-κB activation in mature B cells. Immunity 21 (2004) 629-642
    • (2004) Immunity , vol.21 , pp. 629-642
    • Grech, A.P.1    Amesbury, M.2    Chan, T.3    Gardam, S.4    Basten, A.5    Brink, R.6
  • 14
    • 34547126428 scopus 로고    scopus 로고
    • The inhibitors of apoptosis (IAPs) as cancer targets
    • Hunter A.M., Lacasse E.C., and Korneluk R.G. The inhibitors of apoptosis (IAPs) as cancer targets. Apoptosis 12 (2007) 1543-1568
    • (2007) Apoptosis , vol.12 , pp. 1543-1568
    • Hunter, A.M.1    Lacasse, E.C.2    Korneluk, R.G.3
  • 15
    • 0032014073 scopus 로고    scopus 로고
    • DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κB and AP-1
    • Kasibhatla S., Brunner T., Genestier L., Echeverri F., Mahboubi A., and Green D.R. DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-κB and AP-1. Mol. Cell 1 (1998) 543-551
    • (1998) Mol. Cell , vol.1 , pp. 543-551
    • Kasibhatla, S.1    Brunner, T.2    Genestier, L.3    Echeverri, F.4    Mahboubi, A.5    Green, D.R.6
  • 16
    • 4444243683 scopus 로고    scopus 로고
    • A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death
    • Li L., Thomas R.M., Suzuki H., De Brabander J.K., Wang X., and Harran P.G. A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death. Science 305 (2004) 1471-1474
    • (2004) Science , vol.305 , pp. 1471-1474
    • Li, L.1    Thomas, R.M.2    Suzuki, H.3    De Brabander, J.K.4    Wang, X.5    Harran, P.G.6
  • 17
    • 0037149542 scopus 로고    scopus 로고
    • TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
    • Li X., Yang Y., and Ashwell J.D. TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2. Nature 416 (2002) 345-347
    • (2002) Nature , vol.416 , pp. 345-347
    • Li, X.1    Yang, Y.2    Ashwell, J.D.3
  • 21
    • 0029595282 scopus 로고
    • The TNF-R2-TRAF signaling complex contains two novel proteins related to baculoviral-inhibitor of apoptosis proteins
    • Rothe M., Pan M.G., Henzel W.J., Ayres T.M., and Goeddel D.V. The TNF-R2-TRAF signaling complex contains two novel proteins related to baculoviral-inhibitor of apoptosis proteins. Cell 83 (1995) 1243-1252
    • (1995) Cell , vol.83 , pp. 1243-1252
    • Rothe, M.1    Pan, M.G.2    Henzel, W.J.3    Ayres, T.M.4    Goeddel, D.V.5
  • 22
    • 33644853217 scopus 로고    scopus 로고
    • Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of TRAF2 and Smac
    • Samuel T., Welsh K., Lober T., Togo S.H., Zapata J.M., and Reed J.C. Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of TRAF2 and Smac. J. Biol. Chem. 281 (2006) 1080-1090
    • (2006) J. Biol. Chem. , vol.281 , pp. 1080-1090
    • Samuel, T.1    Welsh, K.2    Lober, T.3    Togo, S.H.4    Zapata, J.M.5    Reed, J.C.6
  • 25
    • 0030447483 scopus 로고    scopus 로고
    • The TNF-R2 signal transducers TRAF2 and c-IAP1 are components of the TNF-R1 signaling complex
    • Shu H.B., Takeuchi M., and Goeddel D.V. The TNF-R2 signal transducers TRAF2 and c-IAP1 are components of the TNF-R1 signaling complex. Proc. Natl. Acad. Sci. USA 93 (1996) 13973-13978
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13973-13978
    • Shu, H.B.1    Takeuchi, M.2    Goeddel, D.V.3
  • 26
    • 1042278168 scopus 로고    scopus 로고
    • Unlike DIABLO/Smac, Grim promotes global ubiquitination and specific degradation of XIAP and neither cause apoptosis
    • Silke J., Kratina T., Ekert P.G., Pakusch M., and Vaux D.L. Unlike DIABLO/Smac, Grim promotes global ubiquitination and specific degradation of XIAP and neither cause apoptosis. J. Biol. Chem. 279 (2004) 4313-4321
    • (2004) J. Biol. Chem. , vol.279 , pp. 4313-4321
    • Silke, J.1    Kratina, T.2    Ekert, P.G.3    Pakusch, M.4    Vaux, D.L.5
  • 28
    • 12344300349 scopus 로고    scopus 로고
    • IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms
    • Tenev T., Zachariou A., Wilson R., Ditzel M., and Meier P. IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms. Nat. Cell Biol. 7 (2005) 70-77
    • (2005) Nat. Cell Biol. , vol.7 , pp. 70-77
    • Tenev, T.1    Zachariou, A.2    Wilson, R.3    Ditzel, M.4    Meier, P.5
  • 29
    • 0029953942 scopus 로고    scopus 로고
    • Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors
    • Uren A.G., Pakusch M., Hawkins C.J., Puls K.L., and Vaux D.L. Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Proc. Natl. Acad. Sci. USA 93 (1996) 4974-4978
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4974-4978
    • Uren, A.G.1    Pakusch, M.2    Hawkins, C.J.3    Puls, K.L.4    Vaux, D.L.5
  • 31
    • 33749389926 scopus 로고    scopus 로고
    • The inhibitor of apoptosis protein fusion c-IAP2/MALT1 stimulates NF-κB activation independently of TRAF1 and TRAF2
    • Varfolomeev E., Wayson S.M., Dixit V.M., Fairbrother W.J., and Vucic D. The inhibitor of apoptosis protein fusion c-IAP2/MALT1 stimulates NF-κB activation independently of TRAF1 and TRAF2. J. Biol. Chem. 281 (2006) 29022-29029
    • (2006) J. Biol. Chem. , vol.281 , pp. 29022-29029
    • Varfolomeev, E.1    Wayson, S.M.2    Dixit, V.M.3    Fairbrother, W.J.4    Vucic, D.5
  • 32
    • 31544470589 scopus 로고    scopus 로고
    • 17-allylamino-17-demethoxygeldanamycin synergistically potentiates tumor necrosis factor-induced lung cancer cell death by blocking the nuclear factor-kappaB pathway
    • Wang X., Ju W., Renouard J., Aden J., Belinsky S.A., and Lin Y. 17-allylamino-17-demethoxygeldanamycin synergistically potentiates tumor necrosis factor-induced lung cancer cell death by blocking the nuclear factor-kappaB pathway. Cancer Res. 66 (2006) 1089-1095
    • (2006) Cancer Res. , vol.66 , pp. 1089-1095
    • Wang, X.1    Ju, W.2    Renouard, J.3    Aden, J.4    Belinsky, S.A.5    Lin, Y.6
  • 33
    • 24944489952 scopus 로고    scopus 로고
    • Stimulus specificity of gene expression programs determined by temporal control of IKK activity
    • Werner S.L., Barken D., and Hoffmann A. Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science 309 (2005) 1857-1861
    • (2005) Science , vol.309 , pp. 1857-1861
    • Werner, S.L.1    Barken, D.2    Hoffmann, A.3
  • 34
    • 2342445559 scopus 로고    scopus 로고
    • Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells
    • Yang Q.H., and Du C. Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells. J. Biol. Chem. 279 (2004) 16963-16970
    • (2004) J. Biol. Chem. , vol.279 , pp. 16963-16970
    • Yang, Q.H.1    Du, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.