CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex.

Cell death & disease

Volumn 4, Issue , 2013, Pages

  Maas, C ^a   Tromp, J M ^b   van Laar, J ^b   Thijssen, R ^b   Elias, J A ^b   Malara, A ^b   Krippner Heidenreich, A ^b   Silke, J ^b   van Oers, M H ^b   Eldering, E ^b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ABT-737; BIPHENYL DERIVATIVE; BIRC2 PROTEIN, HUMAN; BIRC3 PROTEIN, HUMAN; CD40 ANTIGEN; CD40 LIGAND; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; MULTIPROTEIN COMPLEX; NITROPHENOL; PIPERAZINE DERIVATIVE; PROTEASOME; SIGNAL PEPTIDE; SULFONAMIDE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

3T3 CELL LINE; ANIMAL; BIOSYNTHESIS; CELL DEATH; CHRONIC LYMPHATIC LEUKEMIA; DRUG EFFECTS; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOUSE; MUTATION; PATHOLOGY; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION;

3T3 CELLS; ANIMALS; ANTIGENS, CD40; BIPHENYL COMPOUNDS; CD40 LIGAND; CELL DEATH; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MICE; MULTIPROTEIN COMPLEXES; MUTATION; NF-KAPPA B; NITROPHENOLS; PIPERAZINES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; SIGNAL TRANSDUCTION; SULFONAMIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84895855314     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.305     Document Type: Article

References (0)