Small molecule epigenetic inhibitors targeted to histone lysine methyltransferases and demethylases

Quarterly Reviews of Biophysics

Volumn 46, Issue 4, 2014, Pages 349-373

  Wang, Zhanxin ^a,b   Patel, Dinshaw J ^b  

^a Beijing Normal University   (China)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; HISTONE; HISTONE DEMETHYLASE; HISTONE LYSINE METHYLTRANSFERASE; LYSINE;

ANIMAL; BINDING SITE; CHEMISTRY; CHROMATIN; DRUG ANTAGONISM; DRUG DESIGN; DRUG SCREENING; GENETIC EPIGENESIS; GENOME; HUMAN; IC 50; METHYLATION; NUCLEOSOME; REVIEW;

ALLOSTERIC SITE; ANIMALS; CHROMATIN; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; EPIGENESIS, GENETIC; GENOME; HISTONE DEMETHYLASES; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; INHIBITORY CONCENTRATION 50; LYSINE; METHYLATION; NUCLEOSOMES;

EID: 84902919626     PISSN: 00335835     EISSN: 14698994     Source Type: Journal    
DOI: 10.1017/S0033583513000085     Document Type: Review

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