Azalysine analogues as probes for protein lysine deacetylation and demethylation

Journal of the American Chemical Society

Volumn 134, Issue 11, 2012, Pages 5138-5148

  Dancy, Blair C R ^a   Ming, Shonoi A ^a   Papazyan, Romeo ^a   Jelinek, Christine A ^a   Majumdar, Ananya ^b   Sun, Yan ^a   Dancy, Beverley M ^a   Drury, William J ^a   Cotter, Robert J ^a   Taverna, Sean D ^a   Cole, Philip A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADP-RIBOSE; CHEMICAL PROBES; DEACETYLATION; DEMETHYLASE; DEMETHYLATION; HISTONE DEACETYLASES; MECHANISTIC ANALYSIS; POTENT INHIBITOR; SIRTUIN; WESTERN-BLOT ANALYSIS;

ALKYLATION; AMINO ACIDS; CHEMICAL ANALYSIS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES; PROBES; TEACHING;

ACETYLATION;

ADENOSINE DIPHOSPHATE RIBOSE; AZALYSINE DERIVATIVE; HISTONE DEACETYLASE 8; HISTONE DEMETHYLASE; LYSINE; SIRTUIN 1; UNCLASSIFIED DRUG;

ACYLATION AND DEACYLATION; ARTICLE; CATALYSIS; ENZYME MECHANISM; ENZYME STRUCTURE; HISTONE MODIFICATION; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDE SYNTHESIS; PROTEIN PROCESSING; WESTERN BLOTTING;

ACETYLATION; AZA COMPOUNDS; FLUORESCENT DYES; HISTONE DEACETYLASES; HISTONE DEMETHYLASES; LYSINE; METHYLATION; MOLECULAR STRUCTURE; PEPTIDES;

EID: 84863343722     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja209574z     Document Type: Article

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